Identification of metabolites in WZS-miniature pig urine after oral administration of Danshen decoction by HPLC coupled with diode array detection with electrospray ionization tandem ion trap and time-of-flight mass spectrometry

Biomedical Chromatography

Volumn 27, Issue 6, 2013, Pages 720-735

  Zhao, Xin ^a   Yang, Dong Hui ^a   Zhou, Qi Le ^b   Xu, Feng ^a   Zhang, Lei ^a   Liang, Jing ^a   Liu, Guang Xue ^a   Cai, Shao Qing ^a   Yang, Xiu Wei ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b CAPITAL NORMAL UNIVERSITY   (China)

Author keywords

Danshen decoction; HPLC DAD ESI IT TOF MS; Metabolites; Phenolic acid; WZS miniature pig

Indexed keywords

ALKYLATION; AMINO ACIDS; BIOMOLECULES; BODY FLUIDS; COLUMN CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; INDIUM COMPOUNDS; MAMMALS; MASS SPECTROMETRY;

DANSHEN; DANSHEN DECOCTION; DIODE ARRAY DETECTION; HPLC-DAD-ESI-IT-TOF/MS; HPLC/DAD; ION TRAPS; ORAL ADMINISTRATION; PHENOLIC ACIDS; PIG URINE; WZS-MINIATURE PIG;

METABOLITES;

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; CAFFEIC ACID; DRUG METABOLITE; FERULIC ACID; GLYCINE METHYL ESTER; ISOFERULIC ACID; PROTOCATECHUALDEHYDE; PROTOCATECHUIC ACID; ROSMARINIC ACID; SALVIA MILTIORRHIZA EXTRACT; SALVIANOLIC ACID B;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLUMN CHROMATOGRAPHY; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG URINE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; GLUCURONIDATION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGENATION; IN VIVO STUDY; INTESTINE ABSORPTION; ION TRAP MASS SPECTROMETRY; MALE; METHYLATION; MINIPIG; NONHUMAN; SULFATION; TIME OF FLIGHT MASS SPECTROMETRY; URINALYSIS;

SUIDAE;

EID: 84876346781     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2851     Document Type: Article

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