Reconciling a Salmonella enterica metabolic model with experimental data confirms that overexpression of the glyoxylate shunt can rescue a lethal ppc deletion mutant

FEMS Microbiology Letters

Volumn 342, Issue 1, 2013, Pages 62-69

  Fong, Nicole L ^a   Lerman, Joshua A ^a   Lam, Irene ^a   Palsson, Bernhard O ^a   Charusanti, Pep ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Gap filling; Mathematical modeling; Metabolic reconstruction; Systems biology

Indexed keywords

GLYOXYLIC ACID;

ACEBA GENE; ACEBAK GENE; ACEK GENE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL VIABILITY; BIOLOGICAL MODEL; COMPARATIVE STUDY; COMPUTER MODEL; CONTROLLED STUDY; DELETION MUTANT; EXPERIMENTAL STUDY; FEASIBILITY STUDY; GENE; GENE INACTIVATION; GENE INDUCTION; GENE OVEREXPRESSION; GLUCOSE TRANSPORT; GROWTH RATE; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONHUMAN; OPERON; PPC GENE; PRIORITY JOURNAL; SALMONELLA ENTERICA;

CARBOHYDRATE METABOLISM, INBORN ERRORS; GENE DELETION; GENE EXPRESSION; GLYOXYLATES; LIVER DISEASES; METABOLIC NETWORKS AND PATHWAYS; MICROBIAL VIABILITY; MODELS, THEORETICAL; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); SALMONELLA TYPHIMURIUM; SYSTEMS BIOLOGY;

SALMONELLA ENTERICA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

EID: 84876321687     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/1574-6968.12109     Document Type: Article

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