메뉴 건너뛰기




Volumn 9, Issue 4, 2012, Pages 234-241

GNAI1 suppresses tumor cell migration and invasion and is post-transcriptionally regulated by MiR-320a/c/d in hepatocellular carcinoma

Author keywords

GNAI1; HCC; Invasion; Migration; MiR 320

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA 1; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MESSENGER RNA; MICRORNA; MICRORNA 320A; MICRORNA 320C; MICRORNA 320D; MICRORNA 9; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84876321449     PISSN: 20953941     EISSN: None     Source Type: Journal    
DOI: 10.7497/j.issn.2095-3941.2012.04.003     Document Type: Article
Times cited : (64)

References (28)
  • 1
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman AG. G proteins: Transducers of receptor-generated signals. Annu Rev Biochem 1987; 56: 615-649.
    • (1987) Annu Rev Biochem , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 2
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon MI, Strathmann MP, Gautam N. Diversity of G proteins in signal transduction, Science 1991; 252: 802-808.
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 3
    • 0027291886 scopus 로고
    • Inhibition of adenylyl cyclase by Gi alpha
    • Taussig R, Iñiguez-Lluhi JA, Gilman AG. Inhibition of adenylyl cyclase by Gi alpha. Science 1993; 261: 218-221.
    • (1993) Scienc , vol.261 , pp. 218-221
    • Taussig, R.1    Iñiguez-Lluhi, J.A.2    Gilman, A.G.3
  • 4
    • 0035952638 scopus 로고    scopus 로고
    • G protein coupled receptor signaling through the Src and Stat3 pathway: Role in proliferation and transformation
    • Ram PT, Iyengar R. G protein coupled receptor signaling through the Src and Stat3 pathway: Role in proliferation and transformation. Oncogene 2001; 20: 1601-1606.
    • (2001) Oncogene , vol.20 , pp. 1601-1606
    • Ram, P.T.1    Iyengar, R.2
  • 5
    • 6944227703 scopus 로고    scopus 로고
    • Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family
    • Embry AC, Glick JL, Linder ME, et al. Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family. Mol Pharmacol 2004; 66: 1325-1331.
    • (2004) Mol Pharmacol , vol.66 , pp. 1325-1331
    • Embry, A.C.1    Glick, J.L.2    Linder, M.E.3
  • 6
    • 0344654769 scopus 로고    scopus 로고
    • G protein G alpha q/11 and G alpha i1, 2 are activated by pancreastatin receptors in rat liver: Studies with GTP-gamma 35S and azido-GTP-alpha-32P
    • Santos-Alvarez J, Sánchez-Margalet V. G protein G alpha q/11 and G alpha i1, 2 are activated by pancreastatin receptors in rat liver: Studies with GTP-gamma 35S and azido-GTP-alpha-32P. J Cell Biochem 1999; 73: 469-477.
    • (1999) J Cell Biochem , vol.73 , pp. 469-477
    • Santos-Alvarez, J.1    Sánchez-Margalet, V.2
  • 7
    • 34250858195 scopus 로고    scopus 로고
    • Differential partitioning of Galphai1 with the cellular microtubules: A possible mechanism of development of Taxol resistance in human ovarian carcinoma cells
    • Parekh HK, Adikari M, Vennapusa B. Differential partitioning of Galphai1 with the cellular microtubules: A possible mechanism of development of Taxol resistance in human ovarian carcinoma cells. J Mol Signal 2006; 10: 3.
    • (2006) J Mol Signal , vol.10 , pp. 3
    • Parekh, H.K.1    Adikari, M.2    Vennapusa, B.3
  • 8
    • 61849102897 scopus 로고    scopus 로고
    • Inhibitory heterotrimeric GTPbinding proteins inhibit hydrogen peroxide-induced apoptosis by up-regulation of Bcl-2 via NF-kappaB in H1299 human lung cancer cells
    • Seo M, Nam HJ, Kim SY, et al. Inhibitory heterotrimeric GTPbinding proteins inhibit hydrogen peroxide-induced apoptosis by up-regulation of Bcl-2 via NF-kappaB in H1299 human lung cancer cells. Biochem Biophys Res Commun 2009; 381: 153-158.
    • (2009) Biochem Biophys Res Commun , vol.381 , pp. 153-158
    • Seo, M.1    Nam, H.J.2    Kim, S.Y.3
  • 9
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: Target recognition and regulatory functions. Cell 2009; 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 10
    • 33747159113 scopus 로고    scopus 로고
    • The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila
    • Thompson BJ, Cohen SM. The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 2006; 126: 767-774.
    • (2006) Cell , vol.126 , pp. 767-774
    • Thompson, B.J.1    Cohen, S.M.2
  • 11
    • 77957664647 scopus 로고    scopus 로고
    • MicroRNAs as regulators of differentiation and cell fate decisions
    • Ivey KN, Srivastava D. MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell 2010; 7: 36-41.
    • (2010) Cell Stem Cell , vol.7 , pp. 36-41
    • Ivey, K.N.1    Srivastava, D.2
  • 12
    • 72049096984 scopus 로고    scopus 로고
    • MicroRNAs and apoptosis: Implications in the molecular therapy of human disease
    • Yang BF, Lu YJ, Wang ZG. MicroRNAs and apoptosis: Implications in the molecular therapy of human disease. Clin Exp Pharmacol Physiol 2009; 36: 951-960.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 951-960
    • Yang, B.F.1    Lu, Y.J.2    Wang, Z.G.3
  • 13
    • 58149085504 scopus 로고    scopus 로고
    • MicroRNA control in the immune system: Basic principles
    • Xiao C, Rajewsky K. MicroRNA control in the immune system: Basic principles. Cell 2009; 136: 26-36.
    • (2009) Cell , vol.136 , pp. 26-36
    • Xiao, C.1    Rajewsky, K.2
  • 14
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • Poy MN, Eliasson L, Krutzfeldt J, et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 2004; 432: 226-230.
    • (2004) Nature , vol.432 , pp. 226-230
    • Poy, M.N.1    Eliasson, L.2    Krutzfeldt, J.3
  • 15
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 16
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grün D, Poy MN, et al. Combinatorial microRNA target predictions, Nat Genet 2005; 37: 495-500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grün, D.2    Poy, M.N.3
  • 17
    • 77951092028 scopus 로고    scopus 로고
    • Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region
    • Wu S, Huang S, Ding J, et al. Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. Oncogene 2010; 29: 2302-2308.
    • (2010) Oncogene , vol.29 , pp. 2302-2308
    • Wu, S.1    Huang, S.2    Ding, J.3
  • 18
    • 0942276399 scopus 로고    scopus 로고
    • CXCL16 signals via Gi, phosphatidylinositol 3-kinase, Akt, I kappa B kinase, and nuclear factor-kappa B and induces cell-cell adhesion and aortic smooth muscle cell proliferation
    • Chandrasekar B, Bysani S, Mummidi S. CXCL16 signals via Gi, phosphatidylinositol 3-kinase, Akt, I kappa B kinase, and nuclear factor-kappa B and induces cell-cell adhesion and aortic smooth muscle cell proliferation. Biol Chem 2004; 279: 3188-3196.
    • (2004) Biol Chem , vol.279 , pp. 3188-3196
    • Chandrasekar, B.1    Bysani, S.2    Mummidi, S.3
  • 19
    • 33845996572 scopus 로고    scopus 로고
    • Lysophospholipids control integrin-dependent adhesion in splenic B cells through G(i) and G(12)/G(13) family G-proteins but not through G(q)/G(11)
    • Rieken S, Herroeder S, Sassmann A, et al. Lysophospholipids control integrin-dependent adhesion in splenic B cells through G(i) and G(12)/G(13) family G-proteins but not through G(q)/G(11). J Biol Chem. 2006; 281: 36985-36992.
    • (2006) J Biol Chem , vol.281 , pp. 36985-36992
    • Rieken, S.1    Herroeder, S.2    Sassmann, A.3
  • 20
    • 21644476500 scopus 로고    scopus 로고
    • Thrombopoietin complements G(i)-but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation
    • Campus F, Lova P, Bertoni A, et al. Thrombopoietin complements G(i)-but not G(q)-dependent pathways for integrin{alpha}(IIb){beta}(3) activation and platelet aggregation. J Biol Chem 2005; 280: 24386-24395.
    • (2005) J Biol Chem , vol.280 , pp. 24386-24395
    • Campus, F.1    Lova, P.2    Bertoni, A.3
  • 21
    • 78149247966 scopus 로고    scopus 로고
    • Differentiation of human T cells alters their repertoire of G protein alpha-subunits
    • Foley JF, Singh SP, Cantu M, et al. Differentiation of human T cells alters their repertoire of G protein alpha-subunits. J Biol Chem 2010; 285: 35537-35550.
    • (2010) J Biol Chem , vol.285 , pp. 35537-35550
    • Foley, J.F.1    Singh, S.P.2    Cantu, M.3
  • 22
    • 77950622025 scopus 로고    scopus 로고
    • MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma
    • Yao J, Liang L, Huang S, et al. MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma. Hepatology 2010; 51: 846-856.
    • (2010) Hepatology , vol.51 , pp. 846-856
    • Yao, J.1    Liang, L.2    Huang, S.3
  • 24
    • 37549037081 scopus 로고    scopus 로고
    • Endogenous RGS proteins attenuate Galpha (i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells
    • Hurst JH, Henkel PA, Brown AL, et al. Endogenous RGS proteins attenuate Galpha (i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells. Cell Signal 2008; 20: 381-389.
    • (2008) Cell Signal , vol.20 , pp. 381-389
    • Hurst, J.H.1    Henkel, P.A.2    Brown, A.L.3
  • 25
    • 51049119231 scopus 로고    scopus 로고
    • Diagnostic and prognostic microRNAs in stage II colon cancer
    • Schepeler T, Reinert JT, Ostenfeld MS, et al. Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res 2008; 68: 6416-6424.
    • (2008) Cancer Res , vol.68 , pp. 6416-6424
    • Schepeler, T.1    Reinert, J.T.2    Ostenfeld, M.S.3
  • 26
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • Yan LX, Huang XF, Shao Q, et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008; 14: 2348-2360.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3
  • 27
    • 58149277310 scopus 로고    scopus 로고
    • The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma
    • Chen L, Yan HX, Yang W, et al. The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma. J Hepatol 2009; 50: 358-369.
    • (2009) J Hepatol , vol.50 , pp. 358-369
    • Chen, L.1    Yan, H.X.2    Yang, W.3
  • 28
    • 58149201058 scopus 로고    scopus 로고
    • miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation
    • Schaar DG, Medina DJ, Moore DF, et al. miR-320 targets transferrin receptor 1(CD71) and inhibits cell proliferation. Exp Hematol 2009; 37: 245-55.
    • (2009) Exp Hematol , vol.37 , pp. 245-55
    • Schaar, D.G.1    Medina, D.J.2    Moore, D.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.