Proline availability regulates proline-4-hydroxylase synthesis and substrate uptake in proline-hydroxylating recombinant Escherichia coli

Applied and Environmental Microbiology

Volumn 79, Issue 9, 2013, Pages 3091-3100

  Falcioni, Francesco ^a   Blank, Lars M ^b   Frick, Oliver ^a   Karau, Andreas ^c   Bühler, Bruno ^a   Schmida, Andreas ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c EVONIK INDUSTRIES AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

METABOLIC FLUX ANALYSIS; MICROBIAL PHYSIOLOGY; PROLINE DEHYDROGENASE; RECOMBINANT ESCHERICHIA COLI; RESTING CELL ACTIVITY; TRICARBOXYLIC ACID CYCLE; WHOLE CELL BIOCATALYSTS; WHOLE-CELL BIOTRANSFORMATIONS;

CYTOLOGY; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROXYLATION; METABOLISM; PHYSIOLOGY; REDOX REACTIONS;

CELLS;

AMINO ACID; BACTERIOLOGY; BIOTRANSFORMATION; CATABOLISM; CATALYSIS; ENZYME ACTIVITY; FECAL COLIFORM; GENE EXPRESSION; PHYSIOLOGY; RECOMBINATION; SUBSTRATE; THRESHOLD;

ESCHERICHIA COLI;

BACTERIAL PROTEIN; BACTERIAL RNA; CARBON; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; RECOMBINANT PROTEIN;

BIOCATALYSIS; CELL INCLUSION; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; HYDROXYLATION; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSPORT AT THE CELLULAR LEVEL;

BACTERIAL PROTEINS; BIOCATALYSIS; BIOLOGICAL TRANSPORT; CARBON; CARBON ISOTOPES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GENE EXPRESSION; HYDROXYLATION; INCLUSION BODIES; METABOLIC NETWORKS AND PATHWAYS; PROLINE; PROLYL HYDROXYLASES; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; RNA, BACTERIAL;

EID: 84876317115     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.03640-12     Document Type: Article

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