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Volumn 15, Issue 5, 2013, Pages 795-808

Identification of the Mycobacterium tuberculosis protein PE-PGRS62 as a novel effector that functions to block phagosome maturation and inhibit iNOS expression

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PE PGRS62 PROTEIN; RAB7 PROTEIN; UNCLASSIFIED DRUG;

EID: 84876308167     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/cmi.12073     Document Type: Article
Times cited : (45)

References (40)
  • 1
    • 33749997722 scopus 로고    scopus 로고
    • A specific secretion system mediates PPE41 transport in pathogenic mycobacteria
    • Abdallah, A.M., Verboom, T., Hannes, F., Safi, M., Strong, M., Eisenberg, D., etal. (2006) A specific secretion system mediates PPE41 transport in pathogenic mycobacteria. Mol Microbiol 62: 667-679.
    • (2006) Mol Microbiol , vol.62 , pp. 667-679
    • Abdallah, A.M.1    Verboom, T.2    Hannes, F.3    Safi, M.4    Strong, M.5    Eisenberg, D.6
  • 3
  • 5
    • 0032247240 scopus 로고    scopus 로고
    • Preparation of cell-wall fractions from mycobacteria
    • In Parish, T., and Stoker, N.G. (eds). Totowa, NJ: Humana Press.
    • Besra, G.S. (1998) Preparation of cell-wall fractions from mycobacteria. In Methods in Molecular Biology, Mycobacteria Protocols. Parish, T., and Stoker, N.G. (eds). Totowa, NJ: Humana Press, pp. 91-107.
    • (1998) Methods in Molecular Biology, Mycobacteria Protocols , pp. 91-107
    • Besra, G.S.1
  • 6
    • 20544447129 scopus 로고    scopus 로고
    • Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae
    • Bowers, K., and Stevens, T.H. (2005) Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1744: 438-454.
    • (2005) Biochim Biophys Acta , vol.1744 , pp. 438-454
    • Bowers, K.1    Stevens, T.H.2
  • 7
    • 0035177858 scopus 로고    scopus 로고
    • Evidence that mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells
    • Brennan, M.J., Delogu, G., Chen, Y., Bardarov, S., Kriakov, J., Alavi, M., etal. (2001) Evidence that mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells. Infect Immun 69: 7326-7333.
    • (2001) Infect Immun , vol.69 , pp. 7326-7333
    • Brennan, M.J.1    Delogu, G.2    Chen, Y.3    Bardarov, S.4    Kriakov, J.5    Alavi, M.6
  • 8
    • 18444408390 scopus 로고    scopus 로고
    • A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system
    • Campodonico, E.M., Chesnel, L., and Roy, C.R. (2005) A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system. Mol Microbiol 56: 918-933.
    • (2005) Mol Microbiol , vol.56 , pp. 918-933
    • Campodonico, E.M.1    Chesnel, L.2    Roy, C.R.3
  • 9
    • 36549015553 scopus 로고    scopus 로고
    • PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall
    • Cascioferro, A., Delogu, G., Colone, M., Sali, M., Stringaro, A., Arancia, G., etal. (2007) PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall. Mol Microbiol 66: 1536-1547.
    • (2007) Mol Microbiol , vol.66 , pp. 1536-1547
    • Cascioferro, A.1    Delogu, G.2    Colone, M.3    Sali, M.4    Stringaro, A.5    Arancia, G.6
  • 10
    • 0028793282 scopus 로고
    • Phagocytic processing of the macrophage endoparasite, Mycobacterium avium, in comparison to phagosomes which contain Bacillus subtilis or latex beads
    • de Chastellier, C., Lang, T., and Thilo, L. (1995) Phagocytic processing of the macrophage endoparasite, Mycobacterium avium, in comparison to phagosomes which contain Bacillus subtilis or latex beads. Eur J Cell Biol 68: 167-182.
    • (1995) Eur J Cell Biol , vol.68 , pp. 167-182
    • de Chastellier, C.1    Lang, T.2    Thilo, L.3
  • 11
    • 77957265457 scopus 로고    scopus 로고
    • The multifunctional PE_PGRS11 protein from Mycobacterium tuberculosis plays a role in regulating resistance to oxidative stress
    • Chaturvedi, R., Bansal, K., Narayana, Y., Kapoor, N., Sukumar, N., Togarsimalemath, S.K., etal. (2010) The multifunctional PE_PGRS11 protein from Mycobacterium tuberculosis plays a role in regulating resistance to oxidative stress. J Biol Chem 285: 30389-30403.
    • (2010) J Biol Chem , vol.285 , pp. 30389-30403
    • Chaturvedi, R.1    Bansal, K.2    Narayana, Y.3    Kapoor, N.4    Sukumar, N.5    Togarsimalemath, S.K.6
  • 12
    • 0028909199 scopus 로고
    • Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited
    • Clemens, D.L., and Horwitz, M.A. (1995) Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J Exp Med 181: 257-270.
    • (1995) J Exp Med , vol.181 , pp. 257-270
    • Clemens, D.L.1    Horwitz, M.A.2
  • 13
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., etal. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3    Garnier, T.4    Churcher, C.5    Harris, D.6
  • 14
    • 0034743604 scopus 로고    scopus 로고
    • Subcellular localization of the Iitracellular survival-enhancing Eis protein of Mycobacterium tuberculosis
    • Dahl, J.L., Wei, J., Moulder, J.W., Laal, S., and Friedman, R.L. (2001) Subcellular localization of the Iitracellular survival-enhancing Eis protein of Mycobacterium tuberculosis. Infect Immun 69: 4295-4302.
    • (2001) Infect Immun , vol.69 , pp. 4295-4302
    • Dahl, J.L.1    Wei, J.2    Moulder, J.W.3    Laal, S.4    Friedman, R.L.5
  • 15
    • 46449096343 scopus 로고    scopus 로고
    • Mycolic acid modification by the mmaA4 gene of M.tuberculosis modulates IL-12 production
    • Dao, D.N., Sweeney, K., Hsu, T., Gurcha, S.S., Nascimento, I.P., Roshevsky, D., etal. (2008) Mycolic acid modification by the mmaA4 gene of M.tuberculosis modulates IL-12 production. PLoS Pathog 4: e1000081.
    • (2008) PLoS Pathog , vol.4
    • Dao, D.N.1    Sweeney, K.2    Hsu, T.3    Gurcha, S.S.4    Nascimento, I.P.5    Roshevsky, D.6
  • 16
    • 33645236362 scopus 로고    scopus 로고
    • A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis
    • Deb, C., Daniel, J., Sirakova, T.D., Abomoelak, B., Dubey, V.S., and Kolattukudy, P.E. (2006) A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis. J Biol Chem 281: 3866-3875.
    • (2006) J Biol Chem , vol.281 , pp. 3866-3875
    • Deb, C.1    Daniel, J.2    Sirakova, T.D.3    Abomoelak, B.4    Dubey, V.S.5    Kolattukudy, P.E.6
  • 17
    • 2442515282 scopus 로고    scopus 로고
    • Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure
    • Delogu, G., Pusceddu, C., Bua, A., Fadda, G., Brennan, M.J., and Zanetti, S. (2004) Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure. Mol Microbiol 52: 725-733.
    • (2004) Mol Microbiol , vol.52 , pp. 725-733
    • Delogu, G.1    Pusceddu, C.2    Bua, A.3    Fadda, G.4    Brennan, M.J.5    Zanetti, S.6
  • 18
    • 67651245670 scopus 로고    scopus 로고
    • The PE and PPE protein families of Mycobacterium tuberculosis
    • In Kaufmann, S.H., and Rubin, E.J. (eds). Weinheim: Wiley-VCH.
    • Delogu, G., Cole, S.T., and Brosch, R. (2008) The PE and PPE protein families of Mycobacterium tuberculosis. In Handbook of Tuberculosis. Kaufmann, S.H., and Rubin, E.J. (eds). Weinheim: Wiley-VCH, pp. 131-150.
    • (2008) Handbook of Tuberculosis , pp. 131-150
    • Delogu, G.1    Cole, S.T.2    Brosch, R.3
  • 19
    • 0032992211 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis phagosome
    • Deretic, V., and Fratti, R.A. (1999) Mycobacterium tuberculosis phagosome. Mol Microbiol 31: 1603-1609.
    • (1999) Mol Microbiol , vol.31 , pp. 1603-1609
    • Deretic, V.1    Fratti, R.A.2
  • 20
    • 33751323180 scopus 로고    scopus 로고
    • Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions
    • Gey van Pittius, N.C., Sampson, S.L., Lee, H., Kim, Y., van Helden, P.D., and Warren, R.M. (2006) Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol Biol 6: 95.
    • (2006) BMC Evol Biol , vol.6 , pp. 95
    • Gey van Pittius, N.C.1    Sampson, S.L.2    Lee, H.3    van Kim, Y.4    Helden, P.D.5    Warren, R.M.6
  • 21
    • 77954423625 scopus 로고    scopus 로고
    • Expression of PE_PGRS 62 protein in Mycobacterium smegmatis decrease mRNA expression of proinflammatory cytokines IL-1beta, IL-6 in macrophages
    • Huang, Y., Wang, Y., Bai, Y., Wang, Z.G., Yang, L., and Zhao, D. (2010) Expression of PE_PGRS 62 protein in Mycobacterium smegmatis decrease mRNA expression of proinflammatory cytokines IL-1beta, IL-6 in macrophages. Mol Cell Biochem 340: 223-229.
    • (2010) Mol Cell Biochem , vol.340 , pp. 223-229
    • Huang, Y.1    Wang, Y.2    Bai, Y.3    Wang, Z.G.4    Yang, L.5    Zhao, D.6
  • 22
    • 84866973514 scopus 로고    scopus 로고
    • Phagolysosome maturation of macrophages was reduced by PE_PGRS 62 protein expressing in Mycobacterium smegmatis and induced in IFN-gamma priming
    • Huang, Y., Zhou, X., Bai, Y., Yang, L., Yin, X., Wang, Z., etal. (2012) Phagolysosome maturation of macrophages was reduced by PE_PGRS 62 protein expressing in Mycobacterium smegmatis and induced in IFN-gamma priming. Vet Microbiol 160: 117-125.
    • (2012) Vet Microbiol , vol.160 , pp. 117-125
    • Huang, Y.1    Zhou, X.2    Bai, Y.3    Yang, L.4    Yin, X.5    Wang, Z.6
  • 24
    • 0033939453 scopus 로고    scopus 로고
    • Sorting in the endosomal system in yeast and animal cells
    • Lemmon, S.K., and Traub, L.M. (2000) Sorting in the endosomal system in yeast and animal cells. Curr Opin Cell Biol 12: 457-466.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 457-466
    • Lemmon, S.K.1    Traub, L.M.2
  • 25
    • 0035901559 scopus 로고    scopus 로고
    • Expression of microbial virulence proteins in Saccharomyces cerevisiae models mammalian infection
    • Lesser, C.F., and Miller, S.I. (2001) Expression of microbial virulence proteins in Saccharomyces cerevisiae models mammalian infection. EMBO J 20: 1840-1849.
    • (2001) EMBO J , vol.20 , pp. 1840-1849
    • Lesser, C.F.1    Miller, S.I.2
  • 26
    • 80053345905 scopus 로고    scopus 로고
    • SignalP 4.0: discriminating signal peptides from transmembrane regions
    • Petersen, T.N., Brunak, S., von Heijne, G., and Nielsen, H. (2011) SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat Methods 8: 785-786.
    • (2011) Nat Methods , vol.8 , pp. 785-786
    • Petersen, T.N.1    von Brunak, S.2    Heijne, G.3    Nielsen, H.4
  • 27
    • 77951918362 scopus 로고    scopus 로고
    • Identification of the switch in early-to-late endosome transition
    • Poteryaev, D., Datta, S., Ackema, K., Zerial, M., and Spang, A. (2010) Identification of the switch in early-to-late endosome transition. Cell 141: 497-508.
    • (2010) Cell , vol.141 , pp. 497-508
    • Poteryaev, D.1    Datta, S.2    Ackema, K.3    Zerial, M.4    Spang, A.5
  • 28
    • 0035914978 scopus 로고    scopus 로고
    • Processing of Mycobacterium tuberculosis antigen 85B involves intraphagosomal formation of peptide-major histocompatibility complex II complexes and is inhibited by live bacilli that decrease phagosome maturation
    • Ramachandra, L., Noss, E., Boom, W.H., and Harding, C.V. (2001) Processing of Mycobacterium tuberculosis antigen 85B involves intraphagosomal formation of peptide-major histocompatibility complex II complexes and is inhibited by live bacilli that decrease phagosome maturation. J Exp Med 194: 1421-1432.
    • (2001) J Exp Med , vol.194 , pp. 1421-1432
    • Ramachandra, L.1    Noss, E.2    Boom, W.H.3    Harding, C.V.4
  • 29
    • 0034717008 scopus 로고    scopus 로고
    • Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family
    • Ramakrishnan, L., Federspiel, N.A., and Falkow, S. (2000) Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science 288: 1436-1439.
    • (2000) Science , vol.288 , pp. 1436-1439
    • Ramakrishnan, L.1    Federspiel, N.A.2    Falkow, S.3
  • 30
    • 24144442691 scopus 로고    scopus 로고
    • Rab conversion as a mechanism of progression from early to late endosomes
    • Rink, J., Ghigo, E., Kalaidzidis, Y., and Zerial, M. (2005) Rab conversion as a mechanism of progression from early to late endosomes. Cell 122: 735-749.
    • (2005) Cell , vol.122 , pp. 735-749
    • Rink, J.1    Ghigo, E.2    Kalaidzidis, Y.3    Zerial, M.4
  • 31
    • 0030012842 scopus 로고    scopus 로고
    • Mycobacterium avium- and Mycobacterium tuberculosis-containing vacuoles are dynamic, fusion-competent vesicles that are accessible to glycosphingolipids from the host cell plasmalemma
    • Russell, D.G., Dant, J., and Sturgill-Koszycki, S. (1996) Mycobacterium avium- and Mycobacterium tuberculosis-containing vacuoles are dynamic, fusion-competent vesicles that are accessible to glycosphingolipids from the host cell plasmalemma. J Immunol 156: 4764-4773.
    • (1996) J Immunol , vol.156 , pp. 4764-4773
    • Russell, D.G.1    Dant, J.2    Sturgill-Koszycki, S.3
  • 32
    • 0035700015 scopus 로고    scopus 로고
    • Expression, characterization and subcellular localization of the Mycobacterium tuberculosis PPE gene Rv1917c
    • Sampson, S.L., Lukey, P., Warren, R.M., van Helden, P.D., Richardson, M., and Everett, M.J. (2001) Expression, characterization and subcellular localization of the Mycobacterium tuberculosis PPE gene Rv1917c. Tuberculosis (Edinb) 81: 305-317.
    • (2001) Tuberculosis (Edinb) , vol.81 , pp. 305-317
    • Sampson, S.L.1    Lukey, P.2    van Warren, R.M.3    Helden, P.D.4    Richardson, M.5    Everett, M.J.6
  • 33
    • 16344374697 scopus 로고    scopus 로고
    • Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking
    • Shohdy, N., Efe, J.A., Emr, S.D., and Shuman, H.A. (2005) Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking. Proc Natl Acad Sci USA 102: 4866-4871.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4866-4871
    • Shohdy, N.1    Efe, J.A.2    Emr, S.D.3    Shuman, H.A.4
  • 34
    • 0025081151 scopus 로고
    • Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis
    • Snapper, S.B., Melton, R.E., Mustafa, S., Kieser, T., and Jacobs, W.R., Jr (1990) Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis. Mol Microbiol 4: 1911-1919.
    • (1990) Mol Microbiol , vol.4 , pp. 1911-1919
    • Snapper, S.B.1    Melton, R.E.2    Mustafa, S.3    Kieser, T.4    Jacobs Jr., W.R.5
  • 35
    • 0028220231 scopus 로고
    • Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase
    • Sturgill-Koszycki, S., Schlesinger, P.H., Chakraborty, P., Haddix, P.L., Collins, H.L., Fok, A.K., etal. (1994) Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263: 678-681.
    • (1994) Science , vol.263 , pp. 678-681
    • Sturgill-Koszycki, S.1    Schlesinger, P.H.2    Chakraborty, P.3    Haddix, P.L.4    Collins, H.L.5    Fok, A.K.6
  • 36
    • 70349451574 scopus 로고    scopus 로고
    • A broad-range of recombination cloning vectors in mycobacteria
    • Sun, J., Lau, A., Wang, X., Liao, T.Y., Zoubeidi, A., and Hmama, Z. (2009) A broad-range of recombination cloning vectors in mycobacteria. Plasmid 62: 158-165.
    • (2009) Plasmid , vol.62 , pp. 158-165
    • Sun, J.1    Lau, A.2    Wang, X.3    Liao, T.Y.4    Zoubeidi, A.5    Hmama, Z.6
  • 37
    • 26944437440 scopus 로고    scopus 로고
    • Variation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates
    • Talarico, S., Cave, M.D., Marrs, C.F., Foxman, B., Zhang, L., and Yang, Z. (2005) Variation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates. J Clin Microbiol 43: 4954-4960.
    • (2005) J Clin Microbiol , vol.43 , pp. 4954-4960
    • Talarico, S.1    Cave, M.D.2    Marrs, C.F.3    Foxman, B.4    Zhang, L.5    Yang, Z.6
  • 39
    • 84876327912 scopus 로고    scopus 로고
    • World Health Organization Tuberculosis Data and Statistics () Tuberculosis Data Sheet.
    • World Health Organization Tuberculosis Data and Statistics (2011) Tuberculosis Data Sheet. http://www.who.int/tb/en/
    • (2011)
  • 40
    • 0028087919 scopus 로고
    • Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages
    • Xu, S., Cooper, A., Sturgill-Koszycki, S., van Heyningen, T., Chatterjee, D., Orme, I., etal. (1994) Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages. J Immunol 153: 2568-2578.
    • (1994) J Immunol , vol.153 , pp. 2568-2578
    • Xu, S.1    Cooper, A.2    van Sturgill-Koszycki, S.3    Heyningen, T.4    Chatterjee, D.5    Orme, I.6


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