Processing of Mycobacterium tuberculosis antigen 85B involves intraphagosomal formation of peptide-major histocompatibility complex II complexes and is inhibited by live bacilli that decrease phagosome maturation

Journal of Experimental Medicine

Volumn 194, Issue 10, 2001, Pages 1421-1432

  Ramachandra, Lakshmi ^a   Noss, Erika ^a   Boom, W Henry ^a   Harding, Clifford V ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Antigen presentation; Antigen processing; MHC; Mycobacterium tuberculosis; Phagosome

Indexed keywords

BACTERIAL ANTIGEN; GAMMA INTERFERON; H2 ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; MYCOBACTERIUM ANTIGEN; MYCOBACTERIUM ANTIGEN 85B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; ENDOCYTOSIS; IMMUNE SYSTEM; INFECTION CONTROL; MACROPHAGE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; TUBERCULOSIS;

ACYLTRANSFERASES; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; BACTERIAL PROTEINS; BLOTTING, WESTERN; CENTRIFUGATION, DENSITY GRADIENT; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; PHAGOSOMES;

EID: 0035914978     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.10.1421     Document Type: Article

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