Expression of PE-PGRS 62 protein in Mycobacterium smegmatis decrease mRNA expression of proinflammatory cytokines IL-1β, IL-6 in macrophages

Molecular and Cellular Biochemistry

Volumn 340, Issue 1-2, 2010, Pages 223-229

  Huang, Ying ^a   Wang, Yang ^a   Bai, Yu ^a   Wang, Zhi Gang ^b   Yang, Lifeng ^a   Zhao, Deming ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b China Animal Disease Control Center   (China)

Author keywords

IL 6; L 1 ; Macrophages; Mycobacterium; PE PGRS 62 gene

Indexed keywords

BACTERIAL PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PE PGRS 62 PROTEIN; UNCLASSIFIED DRUG; AUTACOID; BACTERIAL ANTIGEN; MEMBRANE PROTEIN; NOS2 PROTEIN, MOUSE; PE-PGRS PROTEIN, MYCOBACTERIUM;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BACTERIAL STRAIN; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RESPONSE; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST CELL; IN VITRO STUDY; MACROPHAGE; MYCOBACTERIOSIS; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PATHOGENESIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CELL LINE; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOUSE; TIME;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION, BACTERIAL; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MACROPHAGES; MEMBRANE PROTEINS; MICE; MYCOBACTERIUM SMEGMATIS; NITRIC OXIDE SYNTHASE TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS;

EID: 77954423625     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0421-x     Document Type: Article

References (35)

1. R de la Rua-Domenech 2006 Human Mycobacterium bovis infection in the United Kingdom: incidence, risks, control measures and review of the zoonotic aspects of bovine tuberculosis Tuberculosis (Edinb) 86 77 109 10.1016/j.tube.2005.05.002 (Pubitemid 43227434)
2. LM O'Reilly CJ Daborn 1995 The epidemiology of Mycobacterium bovis infections in animals and man: a review Tuber Lung Dis 76 Suppl 1 1 46 10.1016/0962-8479(95)90591-X 7579326
3. DM Monack A Mueller S Falkow 2004 Persistent bacterial infections: the interface of the pathogen and the host immune system Nat Rev Microbiol 2 747 765 10.1038/nrmicro955 1:CAS:528:DC%2BD2cXnt1Cntb8%3D 15372085 (Pubitemid 39200066)
4. GR Stewart BD Robertson DB Young 2003 Tuberculosis: a problem with persistence Nat Rev Microbiol 1 97 105 10.1038/nrmicro749 1:CAS:528: DC%2BD3sXosl2hsrw%3D 15035039
5. MS Glickman WR Jacobs Jr 2001 Microbial pathogenesis of Mycobacterium tuberculosis: dawn of a discipline Cell 104 477 485 10.1016/S0092-8674(01)00236- 7 1:CAS:528:DC%2BD3MXis1Kksrk%3D 11239406 (Pubitemid 32203703)
6. ST Cole R Brosch J Parkhill T Garnier C Churcher D Harris SV Gordon K Eiglmeier S Gas CE Barry 3rd F Tekaia K Badcock D Basham D Brown T Chillingworth R Connor R Davies K Devlin T Feltwell S Gentles N Hamlin S Holroyd T Hornsby K Jagels A Krogh J McLean S Moule L Murphy K Oliver J Osborne MA Quail MA Rajandream J Rogers S Rutter K Seeger J Skelton R Squares S Squares JE Sulston K Taylor S Whitehead BG Barrell 1998 Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence Nature 393 537 544 10.1038/31159 1:CAS:528:DyaK1cXjvV2ksrY%3D 9634230 (Pubitemid 28319235)
7. RD Fleischmann D Alland JA Eisen L Carpenter O White J Peterson R DeBoy R Dodson M Gwinn D Haft E Hickey JF Kolonay WC Nelson LA Umayam M Ermolaeva SL Salzberg A Delcher T Utterback J Weidman H Khouri J Gill A Mikula W Bishai WR Jacobs Jr JC Venter Jr CM Fraser 2002 Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains J Bacteriol 184 5479 5490 10.1128/JB.184.19.5479-5490.2002 1:CAS:528:DC%2BD38Xnt1ehtrc%3D 12218036 (Pubitemid 35024395)
8. T Garnier K Eiglmeier JC Camus N Medina H Mansoor M Pryor S Duthoy S Grondin C Lacroix C Monsempe S Simon B Harris R Atkin J Doggett R Mayes L Keating PR Wheeler J Parkhill BG Barrell ST Cole SV Gordon RG Hewinson 2003 The complete genome sequence of Mycobacterium bovis Proc Natl Acad Sci USA 100 7877 7882 10.1073/pnas.1130426100 1:CAS:528:DC%2BD3sXlt1Wqtr4%3D 12788972 (Pubitemid 36760063)
9. MI Voskuil D Schnappinger R Rutherford Y Liu GK Schoolnik 2004 Regulation of the Mycobacterium tuberculosis PE/PPE genes Tuberculosis (Edinb) 84 256 262 10.1016/j.tube.2003.12.014 1:STN:280:DC%2BD2czgs1Kisw%3D%3D (Pubitemid 38857858)
10. MJ Brennan G Delogu 2002 The PE multigene family: a 'molecular mantra' for mycobacteria Trends Microbiol 10 246 249 10.1016/S0966-842X(02)02335-1 1:CAS:528:DC%2BD38XjsFGntLo%3D 11973159 (Pubitemid 34327818)
11. V Dheenadhayalan G Delogu MJ Brennan 2006 Expression of the PE-PGRS 33 protein in Mycobacterium smegmatis triggers necrosis in macrophages and enhanced mycobacterial survival Microbes Infect 8 262 272 10.1016/j.micinf.2005.06.021 1:CAS:528:DC%2BD28Xos1Cgug%3D%3D 16203168 (Pubitemid 43139315)
12. G Delogu C Pusceddu A Bua G Fadda MJ Brennan S Zanetti 2004 Rv1818c-encoded PE-PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure Mol Microbiol 52 725 733 10.1111/j.1365-2958.2004.04007.x 1:CAS:528:DC%2BD2cXktFCitb8%3D 15101979 (Pubitemid 38621743)
13. S Banu N Honore B Saint-Joanis D Philpott MC Prevost ST Cole 2002 Are the PE-PGRS proteins of Mycobacterium tuberculosis variable surface antigens? Mol Microbiol 44 9 19 10.1046/j.1365-2958.2002.02813.x 1:CAS:528: DC%2BD38XjsFGrtrY%3D 11967065 (Pubitemid 34429761)
14. MJ Brennan G Delogu Y Chen S Bardarov J Kriakov M Alavi WR Jacobs Jr 2001 Evidence that mycobacterial PE-PGRS proteins are cell surface constituents that influence interactions with other cells Infect Immun 69 7326 7333 10.1128/IAI.69.12.7326-7333.2001 1:CAS:528:DC%2BD3MXos1Ogu7g%3D 11705904 (Pubitemid 33086555)
15. MG Chaitra S Hariharaputran NR Chandra MS Shaila R Nayak 2005 Defining putative T cell epitopes from PE and PPE families of proteins of Mycobacterium tuberculosis with vaccine potential Vaccine 23 1265 1272 10.1016/j.vaccine.2004. 08.046 1:CAS:528:DC%2BD2MXkslOmtA%3D%3D 15652669 (Pubitemid 40126530)
16. S Basu SK Pathak A Banerjee S Pathak A Bhattacharyya Z Yang S Talarico M Kundu J Basu 2007 Execution of macrophage apoptosis by PE-PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha J Biol Chem 282 1039 1050 10.1074/jbc.M604379200 1:CAS:528:DC%2BD2sXit1KmsA%3D%3D 17095513 (Pubitemid 47076567)
17. G Delogu M Sanguinetti C Pusceddu A Bua MJ Brennan S Zanetti G Fadda 2006 PE-PGRS proteins are differentially expressed by Mycobacterium tuberculosis in host tissues Microbes Infect 8 2061 2067 10.1016/j.micinf.2006.03.015 1:CAS:528:DC%2BD28XpsVOlsrg%3D 16798044 (Pubitemid 44335877)
18. V Dheenadhayalan G Delogu M Sanguinetti G Fadda MJ Brennan 2006 Variable expression patterns of Mycobacterium tuberculosis PE-PGRS genes: evidence that PE-PGRS16 and PE-PGRS26 are inversely regulated in vivo J Bacteriol 188 3721 3725 10.1128/JB.188.10.3721-3725.2006 1:CAS:528:DC%2BD28XkslCksr4%3D 16672626 (Pubitemid 43726235)
19. JC Betts PT Lukey LC Robb RA McAdam K Duncan 2002 Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling Mol Microbiol 43 717 731 10.1046/j.1365-2958.2002. 02779.x 1:CAS:528:DC%2BD38XitlWhurk%3D 11929527 (Pubitemid 34597265)
20. L Ramakrishnan NA Federspiel S Falkow 2000 Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family Science 288 1436 1439 10.1126/science.288.5470.1436 1:CAS:528:DC%2BD3cXjslGqsrs%3D 10827956 (Pubitemid 30366332)
21. G Xu Y Li J Yang X Zhou X Yin M Liu D Zhao 2007 Effect of recombinant Mce4A protein of Mycobacterium bovis on expression of TNF-alpha, iNOS, IL-6, and IL-12 in bovine alveolar macrophages Mol Cell Biochem 302 1 7 10.1007/s11010-006-9395-0 1:CAS:528:DC%2BD2sXotVKqtLs%3D 17530193 (Pubitemid 47202314)
22. SB Snapper RE Melton S Mustafa T Kieser WR Jacobs Jr 1990 Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis Mol Microbiol 4 1911 1919 10.1111/j.1365-2958.1990.tb02040.x 1:CAS:528:DyaK3MXhvVemuw%3D%3D 2082148
23. C-K Stover V-F Cruz T-R Fuerst 1991 New use of BCG for recombinant vaccines Nature 351 456 460 10.1038/351456a0 1:CAS:528:DyaK3MXksVegtbo%3D 1904554
24. SS Master SK Rampini AS Davis C Keller S Ehlers B Springer GS Timmins P Sander V Deretic 2008 Mycobacterium tuberculosis prevents inflammasome activation Cell Host Microbe 3 224 232 10.1016/j.chom.2008.03.003 1:CAS:528:DC%2BD1cXmtlejuro%3D 18407066 (Pubitemid 351494718)
25. BM Saunders AM Cooper 2000 Restraining mycobacteria: role of granulomas in mycobacterial infections Immunol Cell Biol 78 334 341 10.1046/j.1440-1711. 2000.00933.x 1:STN:280:DC%2BD3cvjs1Oquw%3D%3D 10947857 (Pubitemid 30655559)
26. T Hirano T Taga N Nakano K Yasukawa S Kashiwamura K Shimizu K Nakajima KH Pyun T Kishimoto 1985 Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2) Proc Natl Acad Sci USA 82 5490 5494 10.1073/pnas.82.16.5490 1:CAS:528:DyaL2MXlt1Wnt7s%3D 2410927 (Pubitemid 15012129)
27. C Corbel F Melchers 1984 The synergism of accessory cells and of soluble alpha-factors derived from them in the activation of B cells to proliferation Immunol Rev 78 51 74 10.1111/j.1600-065X.1984.tb00476.x 1:STN:280: DyaL2c3jvVWmug%3D%3D 6234223
28. J Weissenbach Y Chernajovsky M Zeevi L Shulman H Soreq U Nir D Wallach M Perricaudet P Tiollais M Revel 1980 Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies Proc Natl Acad Sci USA 77 7152 7156 10.1073/pnas.77.12.7152 1:CAS:528:DyaL3MXhtF2ht70%3D 6164058 (Pubitemid 11190312)
29. C Pasare R Medzhitov 2003 Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells Science 299 1033 1036 10.1126/science.1078231 1:CAS:528:DC%2BD3sXhtFarsLo%3D 12532024 (Pubitemid 36222922)
30. FC Fang 1997 Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity J Clin Invest 99 2818 2825 10.1172/JCI119473 1:CAS:528:DyaK2sXktV2qtLg%3D 9185502
31. John D. MacMicking RJN, LaCourse R, Mudgett JS, Shah SK, Nathan CF (1997) Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc Natl Acad Sci USA 94: 5243-5248
32. J Chan Y Xing RS Magliozzo BR Bloom 1992 Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages J Exp Med 175 1111 1122 10.1084/jem.175.4.1111 1:CAS:528:DyaK38XhslahsLs%3D 1552282
33. J Campuzano D Aguilar K Arriaga JC Leon LP Salas-Rangel J Gonzalez-y-Merchand R Hernandez-Pando C Espitia 2007 The PGRS domain of Mycobacterium tuberculosis PE-PGRS Rv1759c antigen is an efficient subunit vaccine to prevent reactivation in a murine model of chronic tuberculosis Vaccine 25 3722 3729 10.1016/j.vaccine.2006.12.042 1:CAS:528: DC%2BD2sXksV2qtrw%3D 17399860 (Pubitemid 46575088)
34. PJ Cockle SV Gordon A Lalvani BM Buddle RG Hewinson HM Vordermeier 2002 Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics Infect Immun 70 6996 7003 10.1128/IAI.70.12.6996-7003.2002 1:CAS:528: DC%2BD38XptVyhs74%3D 12438379 (Pubitemid 35387935)
35. MG Chaitra R Nayak MS Shaila 2007 Modulation of immune responses in mice to recombinant antigens from PE and PPE families of proteins of Mycobacterium tuberculosis by the Ribi adjuvant Vaccine 25 7168 7176 10.1016/j.vaccine.2007. 07.026 1:CAS:528:DC%2BD2sXhtFWhtLjN 17709160 (Pubitemid 47464671)