Astaxanthin ameliorates lung fibrosis in vivo and in vitro by preventing transdifferentiation, inhibiting proliferation, and promoting apoptosis of activated cells

Food and Chemical Toxicology

Volumn 56, Issue , 2013, Pages 450-458

  Wang, Meirong ^a   Zhang, Jinjin ^a   Song, Xiaodong ^a   Liu, Wenbo ^a   Zhang, Lixia ^a   Wang, Xiuwen ^a   Lv, Changjun ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Astaxanthin; Lung fibrosis; Transdifferentiation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ASTAXANTHIN; BLEOMYCIN; COLLAGEN; COLLAGEN FIBER; DEXAMETHASONE; HYDROXYPROLINE; PROTEIN BCL 2; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ACTIVATION; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; COLLAGEN METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MEGADOSE; FETUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; LUNG ALVEOLUS; LUNG FIBROSIS; MESENCHYME CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION;

ACTINS; APOPTOSIS; BLEOMYCIN; BLOOD-BRAIN BARRIER; CADHERINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; COLLAGEN; DOWN-REGULATION; HUMANS; HYDROXYPROLINE; LUNG; MICROSCOPY, ELECTRON, TRANSMISSION; PULMONARY ALVEOLI; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION; VIMENTIN; XANTHOPHYLLS;

EID: 84876304129     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.03.004     Document Type: Article

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