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Volumn 21, Issue 1, 2013, Pages 93-100

Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; METFORMIN; PLACEBO; TRIACYLGLYCEROL;

EID: 84876293806     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2012.133     Document Type: Article
Times cited : (74)

References (40)
  • 1
    • 3242796634 scopus 로고    scopus 로고
    • Impaired glucose tolerance, but not impaired fasting glucose, is associated with increased levels of coronary heart disease risk factors: Results from the Baltimore Longitudinal Study on Aging
    • DOI 10.2337/diabetes.53.8.2095
    • Blake DR, Meigs JB, Muller DC et al. Impaired glucose tolerance, but not impaired fasting glucose, is associated with increased levels of coronary heart disease risk factors: results from the Baltimore Longitudinal Study on Aging. Diabetes 2004;53: 2095-2100. (Pubitemid 38970760)
    • (2004) Diabetes , vol.53 , Issue.8 , pp. 2095-2100
    • Blake, D.R.1    Meigs, J.B.2    Muller, D.C.3    Najjar, S.S.4    Andres, R.5    Nathan, D.M.6
  • 2
    • 0034604248 scopus 로고    scopus 로고
    • Chronic subclinical inflammation as part of the insulin resistance syndrome: The insulin resistance atherosclerosis study (IRAS)
    • Festa A, D'Agostino R, Howard G, Mykknen L, Tracy RP, Haffner SM. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 2000;102:42-47. (Pubitemid 30430551)
    • (2000) Circulation , vol.102 , Issue.1 , pp. 42-47
    • Festa, A.1    D'Agostino Jr., R.2    Howard, G.3    Mykkanen, L.4    Tracy, R.P.5    Haffner, S.M.6
  • 3
    • 17144389303 scopus 로고    scopus 로고
    • The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: The diabetes prevention program randomized trial
    • Orchard TJ, Temprosa M, Goldberg R et al.; Diabetes Prevention Program Research Group. The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med 2005;142:611-619. (Pubitemid 40529957)
    • (2005) Annals of Internal Medicine , vol.142 , Issue.8 , pp. 611-619
    • Orchard, T.J.1    Temprosa, M.2    Goldberg, R.3    Haffner, S.4    Ratner, R.5    Marcovina, S.6    Fowler, S.7
  • 4
    • 0141835015 scopus 로고    scopus 로고
    • Insulin resistance, inflammation, and the prediabetic state
    • Haffner S. Insulin resistance, inflammation, and the prediabetic state. Am J Cardiol 2003;92:18J-26J.
    • (2003) Am J Cardiol , vol.92
    • Haffner, S.1
  • 5
    • 0036046668 scopus 로고    scopus 로고
    • Impaired glucose tolerance and impaired fasting glycaemia: The current status on definition and intervention
    • DOI 10.1046/j.1464-5491.2002.00835.x
    • Unwin N, Shaw J, Zimmet P, Alberti KG. Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention. Diabet Med 2002;19:708-723. (Pubitemid 35013848)
    • (2002) Diabetic Medicine , vol.19 , Issue.9 , pp. 708-723
    • Unwin, N.1    Shaw, J.2    Zimmet, P.3    Alberti, K.G.M.M.4
  • 7
    • 0028864373 scopus 로고
    • Insulin-stimulated muscle glucose clearance in patients with NIDDM. Effects of one-legged physical training
    • Dela F, Larsen JJ, Mikines KJ et al. Insulin-stimulated muscle glucose clearance in patients with NIDDM. Effects of one-legged physical training. Diabetes 1995;44: 1010-1020.
    • (1995) Diabetes , vol.44 , pp. 1010-1020
    • Dela, F.1    Larsen, J.J.2    Mikines, K.J.3
  • 8
    • 0842310044 scopus 로고    scopus 로고
    • Strength Training Increases Insulin-Mediated Glucose Uptake, GLUT4 Content, and Insulin Signaling in Skeletal Muscle in Patients with Type 2 Diabetes
    • DOI 10.2337/diabetes.53.2.294
    • Holten MK, Zacho M, Gaster M et al. Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes 2004;53:294-305. (Pubitemid 38174543)
    • (2004) Diabetes , vol.53 , Issue.2 , pp. 294-305
    • Holten, M.K.1    Zacho, M.2    Gaster, M.3    Juel, C.4    Wojtaszewski, J.F.P.5    Dela, F.6
  • 10
    • 59449102051 scopus 로고    scopus 로고
    • Anti-inflammatory effect of lifestyle changes in the Finnish Diabetes Prevention Study
    • Finnish Diabetes Prevention Study Group
    • Herder C, Peltonen M, Koenig W et al.; Finnish Diabetes Prevention Study Group. Anti-inflammatory effect of lifestyle changes in the Finnish Diabetes Prevention Study. Diabetologia 2009;52:433-442.
    • (2009) Diabetologia , vol.52 , pp. 433-442
    • Herder, C.1    Peltonen, M.2    Koenig, W.3
  • 11
    • 2542441842 scopus 로고    scopus 로고
    • Effects of exercise, diet and weight loss on high blood pressure
    • DOI 10.2165/00007256-200434050-00003
    • Bacon SL, Sherwood A, Hinderliter A, Blumenthal JA. Effects of exercise, diet and weight loss on high blood pressure. Sports Med 2004;34:307-316. (Pubitemid 38680203)
    • (2004) Sports Medicine , vol.34 , Issue.5 , pp. 307-316
    • Bacon, S.L.1    Sherwood, A.2    Hinderliter, A.3    Blumenthal, J.A.4
  • 14
    • 0029819936 scopus 로고    scopus 로고
    • Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus
    • DOI 10.1210/jc.81.11.4059
    • Cusi K, Consoli A, DeFronzo RA. Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1996;81:4059-4067. (Pubitemid 26380418)
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , Issue.11 , pp. 4059-4067
    • Cusi, K.1    Consoli, A.2    Defronzo, R.A.3
  • 16
    • 74249111367 scopus 로고    scopus 로고
    • Many Americans have pre-diabetes and should be considered for metformin therapy
    • Rhee MK, Herrick K, Ziemer DC et al. Many Americans have pre-diabetes and should be considered for metformin therapy. Diabetes Care 2010;33:49-54.
    • (2010) Diabetes Care , vol.33 , pp. 49-54
    • Rhee, M.K.1    Herrick, K.2    Ziemer, D.C.3
  • 18
    • 67651212318 scopus 로고    scopus 로고
    • The effect of metformin on the incidence of type 2 diabetes mellitus and cardiovascular disease risk factors in overweight and obese subjects-The Carmos study
    • Andreadis EA, Katsanou PM, Georgiopoulos DX et al. The effect of metformin on the incidence of type 2 diabetes mellitus and cardiovascular disease risk factors in overweight and obese subjects-the Carmos study. Exp Clin Endocrinol Diabetes 2009;117:175-180.
    • (2009) Exp Clin Endocrinol Diabetes , vol.117 , pp. 175-180
    • Andreadis, E.A.1    Katsanou, P.M.2    Georgiopoulos, D.X.3
  • 19
    • 84859096202 scopus 로고    scopus 로고
    • Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes
    • Malin SK, Gerber R, Chipkin SR, Braun B. Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes. Diabetes Care 2012;35:131-136.
    • (2012) Diabetes Care , vol.35 , pp. 131-136
    • Malin, S.K.1    Gerber, R.2    Chipkin, S.R.3    Braun, B.4
  • 20
    • 0029037649 scopus 로고
    • Pathophysiology of insulin resistance in human disease
    • Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995;75:473-486.
    • (1995) Physiol Rev , vol.75 , pp. 473-486
    • Reaven, G.M.1
  • 23
    • 48349116165 scopus 로고    scopus 로고
    • Metformin: Effects on micro and macrovascular complications in type 2 diabetes
    • Bailey CJ. Metformin: effects on micro and macrovascular complications in type 2 diabetes. Cardiovasc Drugs Ther 2008;22:215-224.
    • (2008) Cardiovasc Drugs Ther , vol.22 , pp. 215-224
    • Bailey, C.J.1
  • 24
    • 84887212509 scopus 로고    scopus 로고
    • Changes in weight, waist circumference and compensatory responses with different doses of exercise among sedentary, overweight postmenopausal women
    • Church TS, Martin CK, Thompson AM et al. Changes in weight, waist circumference and compensatory responses with different doses of exercise among sedentary, overweight postmenopausal women. PLoS ONE 2009;4:e4515.
    • (2009) PLoS ONE , vol.4
    • Church, T.S.1    Martin, C.K.2    Thompson, A.M.3
  • 26
    • 70349578941 scopus 로고    scopus 로고
    • Metformin in combination with structured lifestyle intervention improved body mass index in obese adolescents, but did not improve insulin resistance
    • Clarson CL, Mahmud FH, Baker JE et al. Metformin in combination with structured lifestyle intervention improved body mass index in obese adolescents, but did not improve insulin resistance. Endocrine 2009;36:141-146.
    • (2009) Endocrine , vol.36 , pp. 141-146
    • Clarson, C.L.1    Mahmud, F.H.2    Baker, J.E.3
  • 27
    • 43549109197 scopus 로고    scopus 로고
    • Addition of metformin to a lifestyle modification program in adolescents with insulin resistance
    • Love-Osborne K, Sheeder J, Zeitler P. Addition of metformin to a lifestyle modification program in adolescents with insulin resistance. J Pediatr 2008;152:817-822.
    • (2008) J Pediatr , vol.152 , pp. 817-822
    • Love-Osborne, K.1    Sheeder, J.2    Zeitler, P.3
  • 28
    • 44949253252 scopus 로고    scopus 로고
    • Use of metformin in obese adolescents with hyperinsulinemia: A 6-month, randomized, double-blind, placebo-controlled clinical trial
    • Atabek ME, Pirgon O. Use of metformin in obese adolescents with hyperinsulinemia: a 6-month, randomized, double-blind, placebo-controlled clinical trial. J Pediatr Endocrinol Metab 2008;21:339-348. (Pubitemid 351802726)
    • (2008) Journal of Pediatric Endocrinology and Metabolism , vol.21 , Issue.4 , pp. 339-348
    • Atabek, M.E.1    Pirgon, O.2
  • 29
    • 0026029277 scopus 로고
    • Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors
    • Landin K, Tengborn L, Smith U. Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors. J Intern Med 1991;229:181-187.
    • (1991) J Intern Med , vol.229 , pp. 181-187
    • Landin, K.1    Tengborn, L.2    Smith, U.3
  • 30
    • 0027494134 scopus 로고
    • Metformin improves glucose, lipid metabolism, and reduces blood pressure in hypertensive, obese women
    • Giugliano D, De Rosa N, Di Maro G et al. Metformin improves glucose, lipid metabolism, and reduces blood pressure in hypertensive, obese women. Diabetes Care 1993;16:1387-1390.
    • (1993) Diabetes Care , vol.16 , pp. 1387-1390
    • Giugliano, D.1    De Rosa, N.2    Di Maro, G.3
  • 34
    • 77956722579 scopus 로고    scopus 로고
    • Nitric oxide and AMPK cooperatively regulate PGC-1 in skeletal muscle cells
    • Lira VA, Brown DL, Lira AK et al. Nitric oxide and AMPK cooperatively regulate PGC-1 in skeletal muscle cells. J Physiol (Lond) 2010;588:3551-3566.
    • (2010) J Physiol (Lond) , vol.588 , pp. 3551-3566
    • Lira, V.A.1    Brown, D.L.2    Lira, A.K.3
  • 35
    • 77949794039 scopus 로고    scopus 로고
    • Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals
    • Sharoff CG, Hagobian TA, Malin SK et al. Combining short-term metformin treatment and one bout of exercise does not increase insulin action in insulin-resistant individuals. Am J Physiol Endocrinol Metab 2010;298:E815-E823.
    • (2010) Am J Physiol Endocrinol Metab , vol.298
    • Sharoff, C.G.1    Hagobian, T.A.2    Malin, S.K.3
  • 36
    • 72449194805 scopus 로고    scopus 로고
    • Exercise training, lipid regulation, and insulin action: A tangled web of cause and effect
    • Kraus WE, Slentz CA. Exercise training, lipid regulation, and insulin action: a tangled web of cause and effect. Obesity (Silver Spring) 2009;17 Suppl 3: S21-S26.
    • (2009) Obesity (Silver Spring) , vol.17 , Issue.SUPPL. 3
    • Kraus, W.E.1    Slentz, C.A.2
  • 39
    • 34247853279 scopus 로고    scopus 로고
    • Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes
    • DOI 10.1042/BJ20061479
    • Koh HJ, Hirshman MF, He H et al. Adrenaline is a critical mediator of acute exercise- induced AMP-activated protein kinase activation in adipocytes. Biochem J 2007;403:473-481. (Pubitemid 46706975)
    • (2007) Biochemical Journal , vol.403 , Issue.3 , pp. 473-481
    • Koh, H.-J.1    Hirshman, M.F.2    He, H.3    Li, Y.4    Manabe, Y.5    Balschi, J.A.6    Goodyear, L.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.