Inactivity, exercise training and detraining, and plasma lipoproteins. STRRIDE: A randomized, controlled study of exercise intensity and amount

Journal of Applied Physiology

Volumn 103, Issue 2, 2007, Pages 432-442

  Slentz, Cris A ^a   Houmard, Joseph A ^b   Johnson, Johanna L ^a   Bateman, Lori A ^a   Tanner, Charles J ^b   McCartney, Jennifer S ^b   Duscha, Brian D ^a   Kraus, William E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Exercise amount; Exercise intensity; Exercise volume; Lipoprotein particle size; Physical inactivity

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ANALYTIC METHOD; ARTICLE; BICYCLE ERGOMETER; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXERCISE; EXERCISE INTENSITY; FEMALE; HUMAN; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN METABOLISM; MAJOR CLINICAL STUDY; MALE; OBESITY; PARTICLE SIZE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SITTING; TRAINING; TREADMILL; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; CARDIOVASCULAR SYSTEM; EXERCISE; EXERCISE TOLERANCE; FEMALE; HUMANS; INSULIN RESISTANCE; LIPIDS; LIPOPROTEINS; MALE; MIDDLE AGED; OBESITY; REST; TIME FACTORS; WEIGHT GAIN;

EID: 34547630302     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01314.2006     Document Type: Article

References (44)

1. Blair S, Kohl HI, Barlow C, Paffenbarger RJ, Gibbons L, Macera C. Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men. JAMA 273: 1093-1098, 1995.
2. Blair S, Kohl HI, Paffenbarger RJ, Clark D, Cooper K, Gibbons L. Physical fitness and all-cause mortality. A prospective study of healthy men and women. JAMA 262: 2395-2401, 1989.
3. Couillard C, Despres J, Lamarche B, Bergeron J, Gagnon J, Leon A, Rao D, Skinner J, Wilmore J, Bouchard C. Effects of endurance training on plasma HDL cholesterol levels depend on levels of triglycerides: evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arterioscler Thromb Vasc Biol 21: 1226-1232, 2001.
4. Duscha B, Slentz C, Johnson J, Houmard J, Bensimhon D, Knetgzer K, Kraus W. Effects of exercise training amount and intensity on peak oxygen consumption in middle-aged men and women at risk for cardiovascular disease. Chest 128: 2788-2793, 2005.
5. Ekelund L, Haskell W, Johnson J, Whaley F, Criqui M, Sheps D. Physical fitness as a predictor of cardiovascular mortality in asymptomatic North American men: the Lipid Research Clinics Mortality Follow-up study. N Engl J Med 319: 1379-1384, 1988.
6. Food and Nutrition Board and Institute of Medicine, National Academies of Science. Physical activity. In: Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). Washington, DC: The National Academies Press, 2005, chapt. 12, p. 880-935 (released 2002).
7. Giada F, Vigna G, Vitale E, Baldo-Enzi G, Bertagilia M, Crecca R, Fellin R. Effect of age on the response of blood lipids, body composition, and aerobic power to physical conditioning and deconditioning. Metabolism 44: 161-165, 1995.
8. Hardman A, Hudson A. Brisk walking and serum lipid and lipoprotein variables in previously sedentary women - effect of 12 weeks training and 12 weeks of detraining. Br J Sp Med 28, 1994.
9. Hardman A, Lawrence J, Herd S. Postprandial lipemia in endurance-trained people during a short interruption to training. J Appl Physiol 84: 1895-1901, 1998.
10. Herd S, Hardman A, Boobis L, Cairns C. The effect of 13 weeks of running training followed by 9 d of detraining on postprandial lipaemia. Br J Sports Med 80: 57-66, 1998.
11. Houmard J, Tanner C, Slentz C, Duscha B, McCartney J, Kraus W. Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol 96: 101-106, 2004.
12. Jin W, Marchadier D, Rader D. Lipases and HDL metabolism. Trends Endocrinol Metab 13: 174-178, 2002.
13. Kamigaki A, Siscovick D, Schwartz S, Psalty B, Edwards K, Raghunathan T, Austin M. Low density lipoprotein particle size and risk of early-onset myocardial infarction in women. Am J Epidemiol 153: 939-945, 2001.
14. Katzmarzyk PT, Church T, Blair S. Cardiorespiratory fitness attenuates the effects of metabolic syndrome on all-cause and cardiovascular disease mortality in men. Arch Intern Med 164: 1092-1097, 2004.
15. Kraus W, Houmard J, Duscha B, Knetgzer K, Wharton M, McCartney J, Bales C, Henes S, Samsa G, Otvos J, Kulkarni K, Slentz C. Exercise training amount and intensity effects on plasma lipoproteins: A randomized, controlled trial. N Engl J Med 347: 1483-1492, 2002.
16. Kraus W, Torgan C, Duscha B, Norris J, Brown S, Cobb F, Bales C, Annex B, Samsa G, Houmard J, Slentz C. Studies of a targeted risk reduction intervention through defined exercise (STRRIDE). Med Sci Sports Exerc 33: 1774-1784, 2001.
17. Kwiterovich PJ. HyperapoB: a pleiotropic phenotype characterized by dense low-density lipoproteins and associated with coronary artery disease. Clin Chem 34: B71-B77, 1988.
18. Lamarche B, Tchernof A, Moorjani S, Cantin B, Dagenais G, Lupien P, Despres J. Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men: prospective results from the Quebec Cardiovascular study. Circulation 95: 69-75, 1997.
19. LeMura L, von Duvillard S, Andreacci J, Klebez J, Chelland S, Russo J. Lipid and lipoprotein profiles, cardiovascular fitness, body composition, and diet during and after resistance, aerobic and combination training in young women. Eur J Appl Physiol 82: 451-458, 2000.
20. Leon A, Sanchez O. Response of blood lipids to exercise training alone or combined with dietary intervention. Med Sci Sports Exerc 33: S502-S515, 2001.
21. Mankowitz K, Seip R, Semenkovich C, Daugherty A, Shonfeld G. Short-term interruption of training affects both fasting and post-prandial lipoproteins. Atherosclerosis 95: 181-189, 1992.
22. Mark D, Lauer M. Exercise Capacity: The prognostic variable that doesn't get enough respect. Circulation 108: 1534-1536, 2003.
23. Meyers J, Prakash M, Froelicher V, Do D, Partington S, Atwood J. Exercise capacity and mortality amount men referred for exercise testing. N Engl J Med 346: 793-801, 2002.
24. Motoyama M, Sunami Y, Kinoshita F, Irie T, Sasaki J, Arakawa K, Kiyonaga A, Tanaka H, Shindo M. The effects of long-term low intensity aerobic training and detraining on serum lipid and lipoprotein concentrations in elderly men and women. Eur J Appl Physiol 70: 126-131, 1995.
25. Nofer J, Kehrel B, Manfred F, Levkau B, Assmann G, Eckardstein A. HDL and arteriosclerosis: beyond reverse cholesterol transport. Atherosclerosis 161: 1-16, 2002.
26. Otvos J, Jeyarajah E, Bennett D, Kraus R. Development of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement. Clin Chem 38: 1632-1638, 1992.
27. Paffenbarger RJ, Hyde R, Wing A, Hsieh C. Physical activity, all-cause mortality and longevity of college alumni. N Engl J Med 314: 605-613, 1986.
28. Paffenbarger RJ, Hyde R, Wing A, Lee IM, Jung D, Kampert J. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med 328: 538-545, 1993.
29. Pascot A, Lemieux I, Prud'homme D, Trembley A, Nadeau A, Couillard C, Bergeron J, Lamarche B, Despres JP. Reduced HDL particle size as an additional feature of the atherogenic dyslipidemia of abdominal obesity. J Lipid Res 42: 2007-2014, 2001.
30. Passmore J. Human energy expenditure. Physiol Rev 35: 801, 1955.
31. Pate R, Pratt M, Blair S, Haskell W, Macera C, Bouchard C, Buchner D, Ettinger W, Heath G, King A. Physical activity and public health. A recommendation from the Centers for Disease Control and the American College of Sports Medicine. JAMA 274: 402-407, 1995.
32. Petibois C, Cassaigne A, Gin H, Deleris G. Lipid profile disorders induced by long-term cessation of physical activity in previously highly endurance-trained subjects. J Clin Endocrinol Metab 89: 3377-3384, 2004.
33. Shulman G. Cellular mechanisms of insulin resistance. J Clin Invest 106: 171-176, 2000.
34. Slattery M, Jacobs DJ. Physical fitness and CVD mortality: the US Railroad Study. Am J Epidemiol 127: 571-580, 1988.
35. Slentz C, Aiken L, Houmard J, Bales C, Johnson J, Tanner C, Duscha B, Kraus W. Inactivity, exercise and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount. J Appl Physiol 99: 1613-1618, 2005.
36. Slentz C, Duscha B, Johnson J, Ketchum K, Aiken L, Samsa G, Houmard J, Bales C, Kraus W. Effects of the amount of exercise on body weight, body composition, and measures of central obesity. STRRIDE-a randomized controlled study. Arch Intern Med 164: 31-39, 2004.
37. Sniderman A, Pedersen T, Kjekshus J. Putting low-density lipoproteins at center stage in atherogenesis. Am J Cardiol 79: 64-67, 1997.
38. Sunami Y, Motoyama M, Kinoshita F, Mizooka Y, Sueta K, Matsunaga A, Sasaki J, Tanaka H, Shindo M. Effects of low-intensity aerobic training on the high-density lipoprotein cholesterol concentration in healthy elderly subjects. Metabolism 48: 984-988, 1999.
39. Sviridov D, Nestel P. Dynamics of reverse cholesterol transport: protection against atherosclerosis. Atherosclerosis 161: 245-254, 2002.
40. Tall AR. Exercise to reduce cardiovascular risk - how much is enough? N Engl J Med 347: 1522-1524, 2002.
41. Thompson C, Thomas T, Araujo J, Albers JJ, Decedue C. Response of HDL cholesterol, apoprotein A-1, and LCAT to exercise withdrawal. Atherosclerosis 54: 65-73, 1985.
42. Vakkilainen J, Makimattila S, Seppala-Lindroos A. Endothelial dysfunction in men with small LDL particles. Circulation 102: 716-721, 2000.
43. Wang J, Chow S. Effects of exercise training and detraining on oxidized LDL-potentiated platelet function in men. Arch Phys Med Rehabil 85: 1531-1537, 2004.
44. Zilversmit D. Atherogenic nature of triglcyerides, postprandial lipidemia, and triglyceride-rich remnant lipoproteins. Clin Chem 41: 153-158, 1995.