-
1
-
-
84876295688
-
-
Center of Disease Control Accessed Jan 10, 2012
-
Center of Disease Control. http://www.cdc.gov/malaria/about/facts.html, Accessed Jan 10, 2012
-
-
-
-
2
-
-
84864334117
-
A revised timeline for the origin of Plasmodium falciparum as a human pathogen
-
10.1007/s00239-011-9476-x
-
Baron JM, Higgins JM, Dzik WH (2010) A revised timeline for the origin of Plasmodium falciparum as a human pathogen. J Mol Evol 73:297-304
-
(2010)
J Mol Evol
, vol.73
, pp. 297-304
-
-
Baron, J.M.1
Higgins, J.M.2
Dzik, W.H.3
-
3
-
-
77954593415
-
A molecular clock for malaria parasites
-
10.1126/science.1188954 1:CAS:528:DC%2BC3cXosVWgu7w%3D
-
Ricklefs RE, Outlaw DC (2010) A molecular clock for malaria parasites. Science 329:226-229
-
(2010)
Science
, vol.329
, pp. 226-229
-
-
Ricklefs, R.E.1
Outlaw, D.C.2
-
4
-
-
0033182111
-
Evolution of Plasmodium and the recent origin of the world populations of Plasmodium falciparum
-
1:CAS:528:DC%2BD3MXjs1Cjs7s%3D
-
Ayala FJ, Escalante AA, Rich SM (1999) Evolution of Plasmodium and the recent origin of the world populations of Plasmodium falciparum. Parassitologia 41:55-68
-
(1999)
Parassitologia
, vol.41
, pp. 55-68
-
-
Ayala, F.J.1
Escalante, A.A.2
Rich, S.M.3
-
5
-
-
79952651273
-
Cluster to evolution of the SERA mutigene family in 18 Plasmodium species
-
10.1371/journal.pone.0017775 1:CAS:528:DC%2BC3MXktVWjtr0%3D
-
Arisue N, Kawai S, Hirai M, Palacpac NM, Jia M, Kaneko A, Tanabe K, Horii T (2011) Cluster to evolution of the SERA mutigene family in 18 Plasmodium species. PLoS ONE 6:e17775
-
(2011)
PLoS ONE
, vol.6
, pp. 17775
-
-
Arisue, N.1
Kawai, S.2
Hirai, M.3
Palacpac, N.M.4
Jia, M.5
Kaneko, A.6
Tanabe, K.7
Horii, T.8
-
6
-
-
0000899457
-
Dihydrofolate Reductases
-
Wiley, New York
-
Blakely RL (ed) (1985) Dihydrofolate Reductases. In: Folates and Pterins, Wiley, New York, pp 191-253
-
(1985)
Folates and Pterins
, pp. 191-253
-
-
Blakely, R.L.1
-
8
-
-
0036289101
-
Highly divergent dihydrofolate reductases conserve complex folding mechanisms
-
10.1006/jmbi.2001.5230 1:CAS:528:DC%2BD38XhsFGjsg%3D%3D
-
Wallace L, Matthews CR (2002) Highly divergent dihydrofolate reductases conserve complex folding mechanisms. J Mol Biol 315:193-211
-
(2002)
J Mol Biol
, vol.315
, pp. 193-211
-
-
Wallace, L.1
Matthews, C.R.2
-
9
-
-
0017748623
-
Folate metabolism in malaria
-
1:CAS:528:DyaE1cXhtValtLs%3D
-
Ferone R (1977) Folate metabolism in malaria. Bull World Health Organ 55:291
-
(1977)
Bull World Health Organ
, vol.55
, pp. 291
-
-
Ferone, R.1
-
10
-
-
0028315470
-
The methotrexate story: A paradigm for development of cancer chemotherapeutic agents
-
10.1016/0065-2571(94)90025-6 1:CAS:528:DyaK2cXmvFWksbY%3D
-
Huennekens FM (1994) The methotrexate story: a paradigm for development of cancer chemotherapeutic agents. Adv Enzyme Regul 34:397
-
(1994)
Adv Enzyme Regul
, vol.34
, pp. 397
-
-
Huennekens, F.M.1
-
11
-
-
0014886077
-
Dihydrofolate reductase inhibitors as antimicrobial agents and their potentiation by sulfonamides
-
10.3109/10408367009043919 1:STN:280:DyaE38%2Fmtlektw%3D%3D
-
Rollo IM (1970) Dihydrofolate reductase inhibitors as antimicrobial agents and their potentiation by sulfonamides. CRC Crit Rev Clin Lab Sci 1:565
-
(1970)
CRC Crit Rev Clin Lab Sci
, vol.1
, pp. 565
-
-
Rollo, I.M.1
-
12
-
-
71749089415
-
Cancer research: From folate antagonism to molecular targets
-
10.1016/j.beha.2009.09.004
-
Bertino JR (2009) Cancer research: from folate antagonism to molecular targets. Best Pract Res Clin Haematol 22:577-582
-
(2009)
Best Pract Res Clin Haematol
, vol.22
, pp. 577-582
-
-
Bertino, J.R.1
-
13
-
-
67650397861
-
Spread and evolution of Plasmodium falciparum drug resistance
-
10.1016/j.parint.2009.04.004 1:CAS:528:DC%2BD1MXos12qs7s%3D
-
Mita T, Tanabe MT, Kita K (2009) Spread and evolution of Plasmodium falciparum drug resistance. Parasit Int 58:201-209
-
(2009)
Parasit Int
, vol.58
, pp. 201-209
-
-
Mita, T.1
Tanabe, M.T.2
Kita, K.3
-
14
-
-
62949106183
-
Mutational 'hot-spots' in mammalian, bacterial and protozoal resistance: Sequence and structural comparison
-
10.1016/j.drup.2009.02.001 1:CAS:528:DC%2BD1MXjvVans7w%3D
-
Volpato JP, Pelletier JN (2009) Mutational 'hot-spots' in mammalian, bacterial and protozoal resistance: sequence and structural comparison. Drug Resist Updat 12:28-41
-
(2009)
Drug Resist Updat
, vol.12
, pp. 28-41
-
-
Volpato, J.P.1
Pelletier, J.N.2
-
15
-
-
33750355062
-
Molecular characterization of Canadian pediatric multi-drug resistant Streptococcus pneumonia from 1998-2004
-
10.1016/j.ijantimicag.2006.08.005 1:CAS:528:DC%2BD28XhtFent77L
-
Zhanel GG, Wang X, Nichol K, Nikulin A, Wierzbowski AK, Mulvey M, Hoban DJ (2006) Molecular characterization of Canadian pediatric multi-drug resistant Streptococcus pneumonia from 1998-2004. Int J Antimicrob Agents 28:465-471
-
(2006)
Int J Antimicrob Agents
, vol.28
, pp. 465-471
-
-
Zhanel, G.G.1
Wang, X.2
Nichol, K.3
Nikulin, A.4
Wierzbowski, A.K.5
Mulvey, M.6
Hoban, D.J.7
-
16
-
-
34250188081
-
Characterization of multidrug resistant Salmonella recovered from diseased animals
-
10.1016/j.vetmic.2007.03.001 1:CAS:528:DC%2BD2sXmsFKlsr4%3D
-
Zhao S, McDermott PF, White DG, Qaiyumi S, Friedman SL, Abbott JW, Glenn A, Ayers SL, Post KW, Fales WH, Wilson RB, Reggiardo C, Walker RD (2007) Characterization of multidrug resistant Salmonella recovered from diseased animals. Vet Microbiol 123:122-132
-
(2007)
Vet Microbiol
, vol.123
, pp. 122-132
-
-
Zhao, S.1
McDermott, P.F.2
White, D.G.3
Qaiyumi, S.4
Friedman, S.L.5
Abbott, J.W.6
Glenn, A.7
Ayers, S.L.8
Post, K.W.9
Fales, W.H.10
Wilson, R.B.11
Reggiardo, C.12
Walker, R.D.13
-
17
-
-
0023630539
-
Spread of chloroquine resistance in Plasmodium falciparum
-
10.1016/0169-4758(87)90147-5 1:STN:280:DC%2BD2cvpvVegtw%3D%3D
-
Payne D (1987) Spread of chloroquine resistance in Plasmodium falciparum. Parasitol Today B 3:241-246
-
(1987)
Parasitol Today B
, vol.3
, pp. 241-246
-
-
Payne, D.1
-
18
-
-
0025951370
-
The development and spread of drug resistant malaria
-
10.1016/0169-4758(91)90262-M 1:STN:280:DC%2BD2cvpvVOmtA%3D%3D
-
Wernsdorfer WH (1991) The development and spread of drug resistant malaria. Parasitol Today 7:297-303
-
(1991)
Parasitol Today
, vol.7
, pp. 297-303
-
-
Wernsdorfer, W.H.1
-
19
-
-
53749089462
-
Genetic evidence for Plasmodium falciparum resistance to chloroquine and pyrimethamine in Indochina and the Western Pacific between 1984 and 1998
-
1:CAS:528:DC%2BD1cXht12iur%2FL
-
Saito-Nakano Y, Tanabe K, Kamei K, Iwagami M, Komaki-Yasuda K, Kawazu S, Kano S, Ohmae H, Endo T (2008) Genetic evidence for Plasmodium falciparum resistance to chloroquine and pyrimethamine in Indochina and the Western Pacific between 1984 and 1998. Am J Trop Med Hyg 79(4):613-619
-
(2008)
Am J Trop Med Hyg
, vol.79
, Issue.4
, pp. 613-619
-
-
Saito-Nakano, Y.1
Tanabe, K.2
Kamei, K.3
Iwagami, M.4
Komaki-Yasuda, K.5
Kawazu, S.6
Kano, S.7
Ohmae, H.8
Endo, T.9
-
20
-
-
0002051540
-
BioEdit: A user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT
-
1:CAS:528:DC%2BD3cXhtVyjs7Y%3D
-
Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser 41:95-98
-
(1999)
Nucl Acids Symp ser
, vol.41
, pp. 95-98
-
-
Hall, T.A.1
-
21
-
-
79957613599
-
MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
-
10.1093/molbev/msr121 1:CAS:528:DC%2BC3MXht1eiu73K
-
Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S (2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28:2731-2739
-
(2011)
Mol Biol Evol
, vol.28
, pp. 2731-2739
-
-
Tamura, K.1
Peterson, D.2
Peterson, N.3
Stecher, G.4
Nei, M.5
Kumar, S.6
-
22
-
-
79960610933
-
Structure-based anaylsis of dihydrofolate reductcase evolution
-
10.1016/j.ympev.2011.06.005 1:CAS:528:DC%2BC3MXptlyht7Y%3D
-
Hecht D, Tran J, Fogel GB (2011) Structure-based anaylsis of dihydrofolate reductcase evolution. Mol Phylo Evol 61:212-230
-
(2011)
Mol Phylo Evol
, vol.61
, pp. 212-230
-
-
Hecht, D.1
Tran, J.2
Fogel, G.B.3
-
23
-
-
0031473847
-
SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
-
10.1002/elps.1150181505 1:CAS:528:DyaK1cXhvFaks70%3D
-
Guex N, Peitsch MC (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18:2714-2723
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
24
-
-
34547844062
-
TOPD/FMTS: A new software to compare phylogenetic trees
-
10.1093/bioinformatics/btm135
-
Puigbò P, Garcia-Vallvé S, McInerney JO (2007) TOPD/FMTS: a new software to compare phylogenetic trees. Bioinformatics 23:1556-1558
-
(2007)
Bioinformatics
, vol.23
, pp. 1556-1558
-
-
Puigbò, P.1
Garcia-Vallvé, S.2
McInerney, J.O.3
-
25
-
-
0019424782
-
Comparison of phylogenetic trees
-
10.1016/0025-5564(81)90043-2
-
Robinson DF, Foulds LR (1981) Comparison of phylogenetic trees. Math Biosci 53:131-147
-
(1981)
Math Biosci
, vol.53
, pp. 131-147
-
-
Robinson, D.F.1
Foulds, L.R.2
-
26
-
-
12044252586
-
Distribution of tree comparison metrics - Some new results
-
Steel MA, Penny D (1993) Distribution of tree comparison metrics - some new results. Syst Biol 42:126-141
-
(1993)
Syst Biol
, vol.42
, pp. 126-141
-
-
Steel, M.A.1
Penny, D.2
-
27
-
-
0002393841
-
The use of tree metrics
-
10.2307/2413347
-
Penny D, Hendy MD (1985) The use of tree metrics. Syst Zool 34:75-82
-
(1985)
Syst Zool
, vol.34
, pp. 75-82
-
-
Penny, D.1
Hendy, M.D.2
-
28
-
-
0031552362
-
Development and validation of a genetic algorithm for flexible docking
-
10.1006/jmbi.1996.0897 1:CAS:528:DyaK2sXis1KntLo%3D
-
Jones G, Willett P, Glen RC, Leach AR, Taylor R (1997) Development and validation of a genetic algorithm for flexible docking. J Mol Biol 267:727-748
-
(1997)
J Mol Biol
, vol.267
, pp. 727-748
-
-
Jones, G.1
Willett, P.2
Glen, R.C.3
Leach, A.R.4
Taylor, R.5
-
29
-
-
62449330667
-
Empirical scoring functions for advanced protein-ligand docking with PLANTS
-
10.1021/ci800298z 1:CAS:528:DC%2BD1MXisVSquw%3D%3D
-
Korb O, Stützle T, Exner TE (2009) Empirical scoring functions for advanced protein-ligand docking with PLANTS. J Chem Inform Model 49:84-96
-
(2009)
J Chem Inform Model
, vol.49
, pp. 84-96
-
-
Korb, O.1
Stützle, T.2
Exner, T.E.3
-
30
-
-
40649099359
-
In Silico screening against wild-type and mutant Plasmodium falciparum Dihydrofolate Reductase
-
10.1016/j.jmgm.2007.10.006 1:CAS:528:DC%2BD1cXjtlyjtbo%3D
-
Fogel GB, Cheung M, Pittman E, Hecht D (2008) In Silico screening against wild-type and mutant Plasmodium falciparum Dihydrofolate Reductase. J Mol Graph Model 26:1145-1152
-
(2008)
J Mol Graph Model
, vol.26
, pp. 1145-1152
-
-
Fogel, G.B.1
Cheung, M.2
Pittman, E.3
Hecht, D.4
-
31
-
-
38649091945
-
Modeling the inhibition of quadruple mutant plasmodium falciparum dihydrofolate reductase by pyrimethamine derivatives
-
10.1007/s10822-007-9152-9 1:CAS:528:DC%2BD1cXps1ahug%3D%3D
-
Fogel GB, Cheung M, Pittman E, Hecht D (2008) Modeling the inhibition of quadruple mutant plasmodium falciparum dihydrofolate reductase by pyrimethamine derivatives. J Comput Aided Mol Des 22:29-38
-
(2008)
J Comput Aided Mol des
, vol.22
, pp. 29-38
-
-
Fogel, G.B.1
Cheung, M.2
Pittman, E.3
Hecht, D.4
-
32
-
-
0037432740
-
Early origin and recent expansion of Plasmodium falciparum
-
10.1126/science.1081449 1:CAS:528:DC%2BD3sXislyqtLo%3D
-
Joy DA, Feng X, Mu J, Furuya T, Chotivanich K, Kretti AU, Ho M, Wang A, White NJ, Suh E, Berrli P, Su X-Z (2003) Early origin and recent expansion of Plasmodium falciparum. Science 300:318-321
-
(2003)
Science
, vol.300
, pp. 318-321
-
-
Joy, D.A.1
Feng, X.2
Mu, J.3
Furuya, T.4
Chotivanich, K.5
Kretti, A.U.6
Ho, M.7
Wang, A.8
White, N.J.9
Suh, E.10
Berrli, P.11
Su, X.-Z.12
-
33
-
-
52449107804
-
Big bang in the evolution of extant malaria parasites
-
10.1093/molbev/msn171 1:CAS:528:DC%2BD1cXht1ektbnK
-
Hayakawa T, Culleton R, Otani H, Horii T, Tanabe K (2008) Big bang in the evolution of extant malaria parasites. Mol Biol Evol 25:2233-2239
-
(2008)
Mol Biol Evol
, vol.25
, pp. 2233-2239
-
-
Hayakawa, T.1
Culleton, R.2
Otani, H.3
Horii, T.4
Tanabe, K.5
-
34
-
-
0028113391
-
Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences
-
10.1073/pnas.91.24.11373 1:CAS:528:DyaK2MXitlyrsrg%3D
-
Escalante AA, Ayala FJ (1994) Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences. Proc Natl Acad Sci USA 91:11373-11377
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11373-11377
-
-
Escalante, A.A.1
Ayala, F.J.2
-
35
-
-
0029002122
-
Evolutionary origin of human and primate malarias: Evidence from the circumsporozoite protein gene
-
1:CAS:528:DyaK2MXmsVOqs7g%3D
-
Escalante AA, Barrio E, Ayala FJ (1995) Evolutionary origin of human and primate malarias: evidence from the circumsporozoite protein gene. Mol Biol Evol 12:616-626
-
(1995)
Mol Biol Evol
, vol.12
, pp. 616-626
-
-
Escalante, A.A.1
Barrio, E.2
Ayala, F.J.3
-
36
-
-
0032493346
-
The evolution of primate malaria parasites based on the gene encoding cytochrome b from the linear mitochondrial genome
-
10.1073/pnas.95.14.8124 1:CAS:528:DyaK1cXks1Skurs%3D
-
Escalante AA, Freeland DE, Collins WE, Lal AA (1998) The evolution of primate malaria parasites based on the gene encoding cytochrome b from the linear mitochondrial genome. Proc Natl Acad Sci USA 95:8124-8129
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8124-8129
-
-
Escalante, A.A.1
Freeland, D.E.2
Collins, W.E.3
Lal, A.A.4
-
37
-
-
0017275995
-
A genetic investigation of virulence in a rodent malaria parasite
-
10.1017/S0031182000048484 1:STN:280:DyaE287nsFaisA%3D%3D
-
Walliker D, Sanderson A, Yoeli M, Hargreaves BJ (1976) A genetic investigation of virulence in a rodent malaria parasite. Parasitology 72:183-194
-
(1976)
Parasitology
, vol.72
, pp. 183-194
-
-
Walliker, D.1
Sanderson, A.2
Yoeli, M.3
Hargreaves, B.J.4
-
38
-
-
38149046559
-
Congenicity and genetic polymorphism in cloned lines derived from a single isolate of a rodent malaria parasite
-
10.1016/j.molbiopara.2007.10.011 1:CAS:528:DC%2BD1cXot1yqsg%3D%3D
-
Pattaradilokrat S, Cheesman SJ, Carter R (2008) Congenicity and genetic polymorphism in cloned lines derived from a single isolate of a rodent malaria parasite. Mol Biochem Parasitol 157:244-247
-
(2008)
Mol Biochem Parasitol
, vol.157
, pp. 244-247
-
-
Pattaradilokrat, S.1
Cheesman, S.J.2
Carter, R.3
-
39
-
-
0024366276
-
Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi
-
1:CAS:528:DyaK3cXitFWktrw%3D
-
Cowman AF, Lew AM (1989) Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi. Mol Cell Biol 9:5182-5188
-
(1989)
Mol Cell Biol
, vol.9
, pp. 5182-5188
-
-
Cowman, A.F.1
Lew, A.M.2
-
40
-
-
0242501573
-
Insights into antifolate resistance from malarial DHFR-TS structures
-
10.1038/nsb921 1:CAS:528:DC%2BD3sXjtFKns74%3D
-
Yuvaniyama J, Chitnumsub P, Kamchonwongpaison S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw M, Yuthavong Y (2003) Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol 10:357-365
-
(2003)
Nat Struct Biol
, vol.10
, pp. 357-365
-
-
Yuvaniyama, J.1
Chitnumsub, P.2
Kamchonwongpaison, S.3
Vanichtanankul, J.4
Sirawaraporn, W.5
Taylor, P.6
Walkinshaw, M.7
Yuthavong, Y.8
-
41
-
-
0031037364
-
Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase
-
10.1073/pnas.94.4.1124 1:CAS:528:DyaK2sXhtlGiu70%3D
-
Sirawaraporn W, Sathikul T, Sirawaraporn R, Yuthavong Y, Santi DV (1997) Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase. Proc Natl Acad Sci USA 94:1124-1129
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1124-1129
-
-
Sirawaraporn, W.1
Sathikul, T.2
Sirawaraporn, R.3
Yuthavong, Y.4
Santi, D.V.5
-
42
-
-
24944558791
-
Crystal structure of dihydrofolate reductase from Plasmodium vivax: Pyrimethamine displacement linked with mutation-induced resistance
-
10.1073/pnas.0501747102 1:CAS:528:DC%2BD2MXhtVaqu7bM
-
Kongsaeree P, Khongsuk P, Leartsakulpanich U, Chitnumsub P, Tarnchombpoo B, Walkinshaw MD, Yuthavong Y (2005) Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resistance. Proc Natl Acad Sci USA 102:13046-13051
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13046-13051
-
-
Kongsaeree, P.1
Khongsuk, P.2
Leartsakulpanich, U.3
Chitnumsub, P.4
Tarnchombpoo, B.5
Walkinshaw, M.D.6
Yuthavong, Y.7
-
43
-
-
0000841123
-
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria
-
10.1073/pnas.85.23.9114 1:CAS:528:DyaL1MXjsVOisg%3D%3D
-
Peterson DS, Walliker D, Wellems TE (1988) Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci USA 85:9114-9118
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 9114-9118
-
-
Peterson, D.S.1
Walliker, D.2
Wellems, T.E.3
-
44
-
-
67749098058
-
Stepwise acquisition of pyrimethamine resistance in the malaria parasite
-
10.1073/pnas.0905922106 1:CAS:528:DC%2BD1MXps1anuro%3D
-
Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL (2009) Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proc Natl Acad Sci USA 106:12025-12030
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12025-12030
-
-
Lozovsky, E.R.1
Chookajorn, T.2
Brown, K.M.3
Imwong, M.4
Shaw, P.J.5
Kamchonwongpaisan, S.6
Neafsey, D.E.7
Weinreich, D.M.8
Hartl, D.L.9
-
45
-
-
78649365006
-
Compensatory mutations restore fitness during the evolution of dihydrofolate reductase
-
10.1093/molbev/msq160 1:CAS:528:DC%2BC3cXhsVeksLrK
-
Brown KM, Costanzo MS, Xu W, Roy S, Lozovsky ER, Hartl DL (2010) Compensatory mutations restore fitness during the evolution of dihydrofolate reductase. Mol Biol Evol 27:2682-2690
-
(2010)
Mol Biol Evol
, vol.27
, pp. 2682-2690
-
-
Brown, K.M.1
Costanzo, M.S.2
Xu, W.3
Roy, S.4
Lozovsky, E.R.5
Hartl, D.L.6
-
46
-
-
80053133668
-
The evolutionary landscape of antifolate resistance in Plasmodium falciparum
-
10.1007/s12041-011-0072-z 1:CAS:528:DC%2BC3MXht1ejtbzM
-
Costanzo MS, Hartl DL (2011) The evolutionary landscape of antifolate resistance in Plasmodium falciparum. J Genet 90:187-190
-
(2011)
J Genet
, vol.90
, pp. 187-190
-
-
Costanzo, M.S.1
Hartl, D.L.2
-
48
-
-
66149089880
-
A novel in silico approach to drug discovery via computational intelligence
-
10.1021/ci9000647 1:CAS:528:DC%2BD1MXktVOlt7g%3D
-
Hecht D, Fogel G (2009) A novel in silico approach to drug discovery via computational intelligence. J Chem Inf Model 49:1105-1121
-
(2009)
J Chem Inf Model
, vol.49
, pp. 1105-1121
-
-
Hecht, D.1
Fogel, G.2
|