Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors

Expert Opinion on Investigational Drugs

Volumn 22, Issue 5, 2013, Pages 551-563

  Reikvam, Håkon ^a,b   Nepstad, Ina ^a   Sulen, André ^a   Gjertsen, Bjorn Tore ^a,b   Hatfield, Kimberley Joanne ^a   Bruserud, Oystein ^a,b  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Acute myeloid leukemia; Apoptosis; Cytokines; Heat shock protein 70; Heat shock protein 90; Proliferation

Indexed keywords

ALVESPIMYCIN; ANTILEUKEMIC AGENT; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 70 INHIBITOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN; VER 155008;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL; CELL PROLIFERATION; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; FEMALE; HEMATOPOIESIS; HUMAN; HUMAN CELL; MALE;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BENZOQUINONES; CELL PROLIFERATION; CELL SURVIVAL; CYTOKINES; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; PURINE NUCLEOSIDES; TUMOR CELLS, CULTURED; YOUNG ADULT;

EID: 84876261155     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2013.791280     Document Type: Article

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