Clinical correlation of circulating heat shock protein 70 in acute leukemia

Leukemia Research

Volumn 34, Issue 5, 2010, Pages 605-609

  Yeh, Chen Hsiung ^a   Tseng, Richard ^a   Hannah, Alison ^c   Estrov, Zeev ^b   Estey, Elihu ^b   Kantarjian, Hagop ^b   Albitar, Maher ^a  

^a QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c Clinical Trial   (United States)

Author keywords

Acute leukemia; Circulating heat shock protein; Survival

Indexed keywords

CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; HEAT SHOCK PROTEIN 70; IDARUBICIN; LACTATE DEHYDROGENASE; METHOTREXATE; RETINOIC ACID; VINCRISTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BURKITT LYMPHOMA; CANCER COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; ELECTROIMMUNOASSAY; FEMALE; GENETIC ASSOCIATION; HUMAN; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; OVERALL SURVIVAL; PHILADELPHIA CHROMOSOME POSITIVE CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SURVIVAL RATE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHEMILUMINESCENT MEASUREMENTS; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOASSAY; KAPLAN-MEIERS ESTIMATE; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 77950090840     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.09.014     Document Type: Article

References (29)

1. Hartl F.U., Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 2002, 295:1852-1858.
2. Jolly C., Morimoto R.I. Role of the heat shock response and molecular chaperones in oncogenesis and cell death. J Natl Cancer Inst 2000, 92:1564-1572.
3. Creagh E.M., Sheehan D., Cotter T.G. Heat shock proteins: modulators of apoptosis in tumour cells. Leukemia 2000, 14:1161-1173.
4. Gurbuxani S., Bruey J.M., Fromentin A., Larmonier N., Parcellier A., Jaattela M., et al. Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells. Oncogene 2001, 20:7478-7485.
5. Schmitt E., Gehrmann M., Brunet M., Multhoff G., Garrido C. Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J Leukocyte Biol 2007, 81:15-27.
6. Multhoff G., Botzler C., Wiesnet M., Müller E., Meier T., Wilmanns W., et al. A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells. Int J Cancer 1995, 61:272-279.
7. Gehrmann M., Schmetzer H., Eissner G., Haferlach T., Hiddemann W., Multhoff G. Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells. Haematologica 2003, 88:474-476.
8. Gehrmann M., Brunner M., Pfister K., Reichle A., Kremmer E., Multhoff G. Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs. Clin Cancer Res 2004, 10:3354-3364.
9. Gehrmann M., Liebisch G., Schmitz G., Anderson R., Steinem C., De Maio A., et al. Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3. PLoS ONE 2008, 3:e1925.
10. Calderwood S.K., Mambula S.S., Gray P.J., Theriault J.R. Extracellular heat shock proteins in cell signaling. FEBS Lett 2007, 581:3689-3694.
11. Barreto A., Gonzalez J.M., Kabingu E., Asea A., Fiorentino S. Stress-induced release of HSC70 from human tumors. Cell Immunol 2003, 222:97-104.
12. Broquet A.H., Thomas G., Masliah J., Trugnan G., Bachelet M. Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J Biol Chem 2003, 278:21601-21606.
13. Saito K., Dai Y., Ohtsuka K. Enhanced expression of heat shock proteins in gradually dying cells and their release from necrotically dead cells. Exp Cell Res 2005, 310:229-236.
14. Lancaster G.I., Febbraio M.A. Exosome-dependent trafficking of HSP70. A novel secretory pathway for cellular stress proteins. J Biol Chem 2005, 280:23349-23355.
15. Gastpar R., Gehrmann M., Bausero M.A., Asea A., Gross C., Schroeder J.A., et al. Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells. Cancer Res 2005, 65:5238-5247.
16. Calderwood S.K. Chaperones and slow death: a recipe for tumor immunotherapy. Trends Biotechnol 2005, 23:57-59.
17. Santarosa M., Favaro D., Quaia M., Galligioni E. Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients. Eur J Cancer 1997, 33:873-877.
18. Nanbu K., Konishi I., Mandai M., Kuroda H., Hamid A.A., Komatsu T., et al. Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. Cancer Detect Prev 1998, 22:549-555.
19. Ray S., Lu Y., Kaufmann S.H., Gustafson W.C., Karp J.E., Boldogh I., et al. Genomic mechanisms of p210BCR-ABL signaling: induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis. J Biol Chem 2004, 279:35604-35615.
20. Vargas-Roig L.M., Gago F.E., Tello O., Aznar J.C., Ciocca D.R. Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy. Int J Cancer 1998, 79:468-475.
21. Brondani Da Rocha A., Regner A., Grivicich I., Pretto Schunemann D., Diel C., Kovaleski G., et al. Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines. Int J Oncol 2004, 25:777-785.
22. Wells A.D., Malkovsky M. Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view. Immunol Today 2000, 21:129-132.
23. Massa C., Guiducci C., Arioli I., Parenza M., Colombo M.P., Melani C. Enhanced efficacy of tumor cell vaccines transfected with secretable HSP70. Cancer Res 2004, 64:1502-1508.
24. Abe M., Manola J.B., Oh W.K., Parslow D.L., George D.J., Austin C.L., et al. Plasma levels of heat shock protein 70 in patients with prostate cancer: a potential biomarker for prostate cancer. Clin Prostate Cancer 2004, 3:49-53.
25. Wheeler D.S., Fisher L.E., Catravas J.D., Jacobs B.R., Carcillo J.A., Wong H.R. Extracellular HSP70 levels in children with septic shock. Pediatr Crit Care Med 2005, 6:308-311.
26. Kimura F., Itoh H., Ambiru S., Shimizu H., Togawa A., Yoshidome H., et al. Circulating heat-shock protein 70 is associated with postoperative infection and organ dysfunction after liver resection. Am J Surg 2004, 187:777-784.
27. Njemini R., Demanet C., Mets T. Inflammatory status as an important determinant of heat shock protein 70 serum concentrations during aging. Biogerontology 2004, 5:31-38.
28. Tallman M.S. Therapy of acute myeloid leukemia. Cancer Control 2001, 8:62-78.
29. Steiner K., Graf M., Hecht K., Reif S., Rossbacher L., Pfister K., et al. High HSP70-membrane expression on leukemic cells from patients with acute myeloid leukemia is associated with a worse prognosis. Leukemia 2006, 20:2076-2079.