SDF-1-CXCR4 axis: Cell trafficking in the cancer stem cell niche of head and neck squamous cell carcinoma

Oncology Reports

Volumn 29, Issue 6, 2013, Pages 2325-2331

  Faber, Anne ^a   Goessler, Ulrich Reinhart ^a   Hoermann, Karl ^a   Schultz, Johannes David ^a   Umbreit, Claudia ^a   Stern Straeter, Jens ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cancer stem cells; CXCR4; Head and neck squamous cell carcinoma; Stem cell niche; Stromal cell derived factor

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER LOCALIZATION; CANCER STEM CELL; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALE; POLARIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD44; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL MOVEMENT; CHEMOKINE CXCL12; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASTIC STEM CELLS; OTORHINOLARYNGOLOGIC NEOPLASMS; RECEPTORS, CXCR4; STEM CELL NICHE;

EID: 84876252582     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2380     Document Type: Article

References (52)

1. Boehm A, Wichmann G, Mozet C and Dietz A: Current therapy options in recurrent head and neck cancer. HNO 58: 762-769, 2010 (In German).
2. Mannelli G and Gallo O: Cancer stem cells hypothesis and stem cells in head and neck cancers. Cancer Treat Rev 38: 515-539, 2012.
3. Prince ME, Sivanandan R, Kaczorowski A, et al: Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 104: 973-978, 2007. (Pubitemid 46154721)
4. Oker N, Kaufmann AM and Albers AE: Biology and relevance of stem cells in squamous head and neck cancer: latest insights and review of literature. Laryngorhinootologie 91: 326-332, 2012 (In German).
5. Clay MR, Tabor M, Owen JH, et al: Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck 32: 1195-1201, 2010.
6. Chen YS, Wu MJ, Huang CY, et al: CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer. PLoS One 6: e28053, 2011.
7. Franzmann EJ, Reategui EP, Pedroso F, et al: Soluble CD44 is a potential marker for the early detection of head and neck cancer. Cancer Epidemiol Biomarkers Prev 16: 1348-1355, 2007. (Pubitemid 47076863)
8. Ponta H, Wainwright D and Herrlich P: The CD44 protein family. Int J Biochem Cell Biol 30: 299-305, 1998. (Pubitemid 28234223)
9. Screaton GR, Bell MV, Bell JI and Jackson DG: The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat. J Biol Chem 268: 12235-12238, 1993. (Pubitemid 23182367)
10. Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U and Bell JI: Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA 89: 12160-12164, 1992. (Pubitemid 23004805)
11. Günthert U, Hofmann M, Rudy W, et al: A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 65: 13-24, 1991. (Pubitemid 121001209)
12. Hofmann M, Rudy W, Zoller M, et al: CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines. Cancer Res 51: 5292-5297, 1991.
13. Zhang H, Xi H, Cai A, et al: Not all side population cells contain cancer stem-like cells in human gastric cancer cell lines. Dig Dis Sci: Aug. 10, 2012 (Epub ahead of print).
14. Pang RW and Poon RT: Cancer stem cell as a potential therapeutic target in hepatocellular carcinoma. Curr Cancer Drug Targets: Aug. 2, 2012 (Epub ahead of print).
15. Park SY, Lee HE, Li H, Shipitsin M, Gelman R and Polyak K: Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer. Clin Cancer Res 16: 876-887, 2010.
16. Zeimet AG, Reimer D, Sopper S, et al: Ovarian cancer stem cells. Neoplasma 59: 747-755, 2012.
17. Dar A, Goichberg P, Shinder V, et al: Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells. Nat Immunol 6: 1038-1046, 2005. (Pubitemid 41486189)
18. Faber A, Roderburg C, Wein F, et al: The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cells. J Biomed Biotechnol 2007: 26065, 2007.
19. De La Luz Sierra M, Yang F, Narazaki M, et al: Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity. Blood 103: 2452-2459, 2004. (Pubitemid 38392993)
20. Shirozu M, Nakano T, Inazawa J, et al: Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics 28: 495-500, 1995.
21. Kim CH and Broxmeyer HE: In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment. Blood 91: 100-110, 1998. (Pubitemid 28018733)
22. + hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood 91: 4523-4530, 1998.
23. Petit I, Goichberg P, Spiegel A, et al: Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. J Clin Invest 115: 168-176, 2005. (Pubitemid 40385518)
24. Chute JP: Stem cell homing. Curr Opin Hematol 13: 399-406, 2006.
25. Fruehauf S, Srbic K, Seggewiss R, Topaly J and Ho AD: Functional characterization of podia formation in normal and malignant hematopoietic cells. J Leukoc Biol 71: 425-432, 2002.
26. Lataillade JJ, Clay D, Dupuy C, et al: Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood 95: 756-768, 2000. (Pubitemid 30062693)
27. Broxmeyer HE, Kohli L, Kim CH, et al: Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells. J Leukoc Biol 73: 630-638, 2003. (Pubitemid 38040476)
28. Kijowski J, Baj-Krzyworzeka M, Majka M, et al: The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. Stem Cells 19: 453-466, 2001. (Pubitemid 32900088)
29. Hattori K, Heissig B, Tashiro K, et al: Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood 97: 3354-3360, 2001.
30. Kremer KN, Clift IC, Miamen AG, et al: Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses. J Immunol 187: 1440-1447, 2011.
31. La Porta CA: Thoughts about cancer stem cells in solid tumors. World J Stem Cells 4: 17-20, 2012.
32. Grosse-Gehling P, Fargeas CA, Dittfeld C, et al: CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges. J Pathol: Aug. 16, 2012 (Epub ahead of print).
33. Schubert M, Herbert N, Taubert I, et al: Differential survival of AML subpopulations in NOD/SCID mice. Exp Hematol 39: 250-263, 2011.
34. Jamal M, Rath BH, Tsang PS, Camphausen K and Tofilon PJ: The brain microenvironment preferentially enhances the radioresistance of CD133(+) glioblastoma stem-like cells. Neoplasia 14: 150-158, 2012.
35. Wollenberg B: Implication of stem cells in the biology and therapy of head and neck cancer. Laryngorhinootologie 90 (Suppl 1): S110-S119, 2011 (In German).
36. + cancer stem cells from human glioblastoma cell line U138MG using multiple assays. Cell Biol Int: Jul. 6, 2012 (Epub ahead of print).
37. Jaggupilli A and Elkord E: Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity. Clin Dev Immunol 2012: 708036, 2012.
38. Pries R, Wittkopf N, Hasselbacher K and Wollenberg B: Constitutive expression of the potential stem cell marker CD44 in permanent HNSCC cell lines. HNO 56: 461-466, 2008 (In German).
39. Badve S and Nakshatri H: Breast-cancer stem cells - beyond semantics. Lancet Oncol 13: e43-e48, 2012.
40. Jiang F, Qiu Q, Khanna A, et al: Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res 7: 330-338, 2009.
41. Charafe-Jauffret E, Ginestier C, Iovino F, et al: Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res 16: 45-55, 2012.
42. Silva IA, Bai S, McLean K, et al: Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. Cancer Res 71: 3991-4001, 2011.
43. Sterz CM, Kulle C, Dakic B, et al: A basal-cell-like compartment in head and neck squamous cell carcinomas represents the invasive front of the tumor and is expressing MMP-9. Oral Oncol 46: 116-122, 2010.
44. Nakajima M, Gohji K, Fabra A, Fidler IA and Tsuruo T: Regulation of tumor metastasis and extracellular matrix degradative enzyme production by microenvironments. Gan To Kagaku Ryoho 20: 380-386, 1993 (In Japanese). (Pubitemid 23124171)
45. Schultz JD, Rotunno S, Erben P, et al: Down-regulation of MMP-2 expression due to inhibition of receptor tyrosine kinases by imatinib and carboplatin in HNSCC. Oncol Rep 25: 1145-1151, 2011.
46. Teicher BA and Fricker SP: CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res 16: 2927-2931, 2010.
47. Metzen E, Jin F, Brockmeier U and Otterbach F: New insight into the SDF-1/CXCR4 axis in a breast carcinoma model: hypoxia-induced endothelial SDF-1 and tumor cell CXCR4 are required for tumor cell intravasation. Mol Cancer Res 10: 1021-1031, 2012.
48. Purizaca J, Meza I and Pelayo R: Early lymphoid development and microenvironmental cues in B-cell acute lymphoblastic leukemia. Arch Med Res 43: 89-101, 2012.
49. Juarez J, Dela Pena A, Baraz R, et al: CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment. Leukemia 21: 1249-1257, 2007. (Pubitemid 46831814)
50. Clatot F, Picquenot JM, Choussy O, et al: Intratumoural level of SDF-1 correlates with survival in head and neck squamous cell carcinoma. Oral Oncol 47: 1062-1068, 2011.
51. Geutskens SB, Andrews WD, van Stalborch AM, et al: Control of human hematopoietic stem/progenitor cell migration by the extracellular matrix protein Slit3. Lab Invest 92: 1129-1139, 2012.
52. Ghosh MC, Makena PS, Gorantla V, Sinclair SE and Waters CM: CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2. Am J Physiol Lung Cell Mol Physiol 302: L846-L856, 2012.