Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP Impact on Lymphangiogenesis

Journal of Biological Chemistry

Volumn 288, Issue 15, 2013, Pages 10195-10204

  Ingvarsen, Signe ^a,b   Porse, Astrid ^a   Erpicum, Charlotte ^c   Maertens, Ludovic ^c   Jürgensen, Henrik J ^a   Madsen, Daniel H ^a   Melander, Maria C ^a   Gardsvoll, Henrik ^a   Hoyer Hansen, Gunilla ^a   Noel, Agnes ^c   Holmbeck, Kenn ^d   Engelholm, Lars H ^a   Behrendt, Niels ^a  

^a FINSEN LABORATORY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN MATRICES; EXTRACELLULAR MATRIX REMODELING; LYMPHATIC VESSELS; MATRIX METALLOPROTEASE; PROTEOLYTIC ACTIVITIES; SPECIFIC INHIBITORS; THERAPEUTIC STRATEGY; TISSUE DESTRUCTION;

ENDOTHELIAL CELLS; MONOCLONAL ANTIBODIES; TISSUE;

ENZYMES;

COLLAGEN; ENZYME PRECURSOR; ILOMASTAT; MATRIX METALLOPROTEINASE 14; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 9E8; PROGELATINASE A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL CULTURE; CELL GROWTH; COLLAGEN DEGRADATION; CONTROLLED STUDY; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPH VESSEL; LYMPH VESSEL ENDOTHELIUM; LYMPHANGIOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION;

ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CHO CELLS; CRICETINAE; ENZYME ACTIVATION; ENZYME PRECURSORS; EXTRACELLULAR MATRIX; GELATINASES; HUMANS; LYMPHANGIOGENESIS; MATRIX METALLOPROTEINASE 14; MICE; MICE, KNOCKOUT; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 84876237128     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.447169     Document Type: Article

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