메뉴 건너뛰기




Volumn 19, Issue 3, 2013, Pages 209-220

High-density cell systems incorporating polymer microspheres as microenvironmental regulators in engineered cartilage tissues

Author keywords

[No Author keywords available]

Indexed keywords

ARTICULAR CARTILAGES; BIOMATERIAL SCAFFOLDS; CELL-BIOMATERIAL INTERACTIONS; ENGINEERED CARTILAGE; ENGINEERING APPROACHES; POLYMER MICROSPHERES; STRUCTURAL ELEMENTS; TISSUE-ENGINEERED THERAPIES;

EID: 84876204506     PISSN: 19373368     EISSN: 19373376     Source Type: Journal    
DOI: 10.1089/ten.teb.2012.0252     Document Type: Review
Times cited : (38)

References (86)
  • 1
    • 0242289511 scopus 로고    scopus 로고
    • Biomechanical strategies for articular cartilage regeneration
    • Darling, E.M., and Athanasiou, K.A. Biomechanical strategies for articular cartilage regeneration. Ann Biomed Eng 31, 1114, 2003.
    • (2003) Ann Biomed Eng , vol.31 , pp. 1114
    • Darling, E.M.1    Athanasiou, K.A.2
  • 2
    • 0141920503 scopus 로고    scopus 로고
    • Burden of major musculoskeletal conditions
    • Woolf, A.D., and Pfleger, B. Burden of major musculoskeletal conditions. Bull World Health Organ 81, 646, 2003.
    • (2003) Bull World Health Organ , vol.81 , pp. 646
    • Woolf, A.D.1    Pfleger, B.2
  • 3
    • 0037963685 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells and cell-based tissue engineering
    • Tuan, R.S., Boland, G., and Tuli, R. Adult mesenchymal stem cells and cell-based tissue engineering. Arthritis Res Ther 5, 32, 2003.
    • (2003) Arthritis Res Ther , vol.5 , pp. 32
    • Tuan, R.S.1    Boland, G.2    Tuli, R.3
  • 4
    • 79958862928 scopus 로고    scopus 로고
    • Recent developments in the treatment of osteoarthritis with NSAIDs
    • Argoff, C.E. Recent developments in the treatment of osteoarthritis with NSAIDs. Curr Med Res Opin 27, 1315, 2011.
    • (2011) Curr Med Res Opin , vol.27 , pp. 1315
    • Argoff, C.E.1
  • 9
    • 0034268813 scopus 로고    scopus 로고
    • Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee
    • Lee, C.R., Grodzinsky, A.J., Hsu, H.P., Martin, S.D., and Spector, M. Effects of harvest and selected cartilage repair procedures on the physical and biochemical properties of articular cartilage in the canine knee. J Orthop Res 18, 790, 2000.
    • (2000) J Orthop Res , vol.18 , pp. 790
    • Lee, C.R.1    Grodzinsky, A.J.2    Hsu, H.P.3    Martin, S.D.4    Spector, M.5
  • 10
    • 84855166240 scopus 로고    scopus 로고
    • Chondral repair of the knee joint using mosaicplasty
    • Robert, H. Chondral repair of the knee joint using mosaicplasty. Orthop Traumatol Surg Res 97, 418, 2011.
    • (2011) Orthop Traumatol Surg Res , vol.97 , pp. 418
    • Robert, H.1
  • 11
    • 22444448450 scopus 로고    scopus 로고
    • Current strategies for articular cartilage repair
    • Redman, S.N., Oldfield, S.F., and Archer, C.W. Current strategies for articular cartilage repair. Eur Cell Mater 9, 23, 2005.
    • (2005) Eur Cell Mater , vol.9 , pp. 23
    • Redman, S.N.1    Oldfield, S.F.2    Archer, C.W.3
  • 12
    • 77953310224 scopus 로고    scopus 로고
    • Clinical experiences with autologous osteochondral mosaicplasty in an athletic population: A 17-year prospective multicenter study
    • Hangody, L., Dobos, J., Balo, E., Panics, G., Hangody, L.R., and Berkes, I. Clinical experiences with autologous osteochondral mosaicplasty in an athletic population: a 17-year prospective multicenter study. Am J Sports Med 38, 1125, 2010.
    • (2010) Am J Sports Med , vol.38 , pp. 1125
    • Hangody, L.1    Dobos, J.2    Balo, E.3    Panics, G.4    Hangody, L.R.5    Berkes, I.6
  • 13
    • 84864927111 scopus 로고    scopus 로고
    • Transmission of infection with human allografts: Essential considerations in donor screening
    • Fishman, J.A., Greenwald, M.A., and Grossi, P.A. Transmission of infection with human allografts: essential considerations in donor screening. Clin Infect Dis 55, 720, 2012.
    • (2012) Clin Infect Dis , vol.55 , pp. 720
    • Fishman, J.A.1    Greenwald, M.A.2    Grossi, P.A.3
  • 14
    • 79955147069 scopus 로고    scopus 로고
    • Update in surgery for osteoarthritis of the knee
    • Choong, P.F., and Dowsey, M.M. Update in surgery for osteoarthritis of the knee. Int J Rheum Dis 14, 167, 2011.
    • (2011) Int J Rheum Dis , vol.14 , pp. 167
    • Choong, P.F.1    Dowsey, M.M.2
  • 15
  • 16
    • 34247465485 scopus 로고    scopus 로고
    • Cartilage tissue engineering for laryngotracheal reconstruction: Comparison of chondrocytes from three anatomic locations in the rabbit
    • Henderson, J.H., Welter, J.F., Mansour, J.M., Niyibizi, C., Caplan, A.I., and Dennis, J.E. Cartilage tissue engineering for laryngotracheal reconstruction: comparison of chondrocytes from three anatomic locations in the rabbit. Tissue Eng 13, 843, 2007.
    • (2007) Tissue Eng , vol.13 , pp. 843
    • Henderson, J.H.1    Welter, J.F.2    Mansour, J.M.3    Niyibizi, C.4    Caplan, A.I.5    Dennis, J.E.6
  • 17
    • 34247561381 scopus 로고    scopus 로고
    • Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering
    • Park, H., Temenoff, J.S., Tabata, Y., Caplan, A.I., and Mikos, A.G. Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials 28, 3217, 2007.
    • (2007) Biomaterials , vol.28 , pp. 3217
    • Park, H.1    Temenoff, J.S.2    Tabata, Y.3    Caplan, A.I.4    Mikos, A.G.5
  • 18
    • 0034897478 scopus 로고    scopus 로고
    • Tissue-engineered fabrication of an osteochondral composite graft using rat bone marrow-derived mesenchymal stem cells
    • Gao, J., Dennis, J.E., Solchaga, L.A., Awadallah, A.S., Goldberg, V.M., and Caplan, A.I. Tissue-engineered fabrication of an osteochondral composite graft using rat bone marrow-derived mesenchymal stem cells. Tissue Eng 7, 363, 2001.
    • (2001) Tissue Eng , vol.7 , pp. 363
    • Gao, J.1    Dennis, J.E.2    Solchaga, L.A.3    Awadallah, A.S.4    Goldberg, V.M.5    Caplan, A.I.6
  • 19
    • 77049109926 scopus 로고    scopus 로고
    • Chondrogenesis of adult stem cells from adipose tissue and bone marrow: Induction by growth factors and cartilage-derived matrix
    • Diekman, B.O., Rowland, C.R., Lennon, D.P., Caplan, A.I., and Guilak, F. Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix. Tissue Eng Part A 16, 523, 2010.
    • (2010) Tissue Eng Part A , vol.16 , pp. 523
    • Diekman, B.O.1    Rowland, C.R.2    Lennon, D.P.3    Caplan, A.I.4    Guilak, F.5
  • 20
    • 1242295266 scopus 로고    scopus 로고
    • Chondrogenic differentiation of adiposederived adult stem cells in agarose, alginate, and gelatin scaffolds
    • Awad, H.A., Wickham, M.Q., Leddy, H.A., Gimble, J.M., and Guilak, F. Chondrogenic differentiation of adiposederived adult stem cells in agarose, alginate, and gelatin scaffolds. Biomaterials 25, 3211, 2004.
    • (2004) Biomaterials , vol.25 , pp. 3211
    • Awad, H.A.1    Wickham, M.Q.2    Leddy, H.A.3    Gimble, J.M.4    Guilak, F.5
  • 21
  • 22
    • 0031817577 scopus 로고    scopus 로고
    • In vitro chondrogenesis of bone marrowderived mesenchymal progenitor cells
    • Johnstone, B., Hering, T.M., Caplan, A.I., Goldberg, V.M., and Yoo, J.U. In vitro chondrogenesis of bone marrowderived mesenchymal progenitor cells. Exp Cell Res 238, 265, 1998.
    • (1998) Exp Cell Res , vol.238 , pp. 265
    • Johnstone, B.1    Hering, T.M.2    Caplan, A.I.3    Goldberg, V.M.4    Yoo, J.U.5
  • 23
    • 36249000024 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human bone marrow stem cells in transwell cultures: Generation of scaffold-free cartilage
    • Murdoch, A.D., Grady, L.M., Ablett, M.P., Katopodi, T., Meadows, R.S., and Hardingham, T.E. Chondrogenic differentiation of human bone marrow stem cells in transwell cultures: generation of scaffold-free cartilage. Stem Cells 25, 2786, 2007.
    • (2007) Stem Cells , vol.25 , pp. 2786
    • Murdoch, A.D.1    Grady, L.M.2    Ablett, M.P.3    Katopodi, T.4    Meadows, R.S.5    Hardingham, T.E.6
  • 24
    • 0000578058 scopus 로고
    • The loss of phenotypic traits by differentiated cells in vitro I. Dedifferentiation of cartilage cells
    • Holtzer, H., Abbott, J., Lash, J., and Holtzer, S. The Loss of Phenotypic Traits by Differentiated Cells in Vitro, I. Dedifferentiation of Cartilage Cells. Proc Natl Acad Sci USA 46, 1533, 1960.
    • (1960) Proc Natl Acad Sci USA , vol.46 , pp. 1533
    • Holtzer, H.1    Abbott, J.2    Lash, J.3    Holtzer, S.4
  • 25
    • 28444491801 scopus 로고    scopus 로고
    • Clonal analysis of the differentiation potential of human adipose-derived adult stem cells
    • Guilak, F., Lott, K.E., Awad, H.A., Cao, Q., Hicok, K.C., Fermor, B., and Gimble, J.M. Clonal analysis of the differentiation potential of human adipose-derived adult stem cells. J Cell Physiol 206, 229, 2006.
    • (2006) J Cell Physiol , vol.206 , pp. 229
    • Guilak, F.1    Lott, K.E.2    Awad, H.A.3    Cao, Q.4    Hicok, K.C.5    Fermor, B.6    Gimble, J.M.7
  • 27
    • 0014099061 scopus 로고
    • Isolation and culture of chondrocytes from human adult articular cartilage
    • Manning, W.K., and Bonner, W.M., Jr. Isolation and culture of chondrocytes from human adult articular cartilage. Arthritis Rheum 10, 235, 1967.
    • (1967) Arthritis Rheum , vol.10 , pp. 235
    • Manning, W.K.1    Bonner Jr., W.M.2
  • 28
    • 70349767672 scopus 로고    scopus 로고
    • Effect of oxygen concentration, culture format and donor variability on in vitro chondrogenesis of human adipose tissue-derived stem cells
    • Pilgaard, L., Lund, P., Duroux, M., Fink, T., Ulrich-Vinther, M., Soballe, K., and Zachar, V. Effect of oxygen concentration, culture format and donor variability on in vitro chondrogenesis of human adipose tissue-derived stem cells. Regen Med 4, 539, 2009.
    • (2009) Regen Med , vol.4 , pp. 539
    • Pilgaard, L.1    Lund, P.2    Duroux, M.3    Fink, T.4    Ulrich-Vinther, M.5    Soballe, K.6    Zachar, V.7
  • 30
    • 36549054396 scopus 로고    scopus 로고
    • Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology
    • Scharstuhl, A., Schewe, B., Benz, K., Gaissmaier, C., Buhring, H.J., and Stoop, R. Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology. Stem Cells 25, 3244, 2007.
    • (2007) Stem Cells , vol.25 , pp. 3244
    • Scharstuhl, A.1    Schewe, B.2    Benz, K.3    Gaissmaier, C.4    Buhring, H.J.5    Stoop, R.6
  • 31
    • 77955714347 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human mesenchymal stem cells: A comparison between micromass and pellet culture systems
    • Zhang, L., Su, P., Xu, C., Yang, J., Yu, W., and Huang, D. Chondrogenic differentiation of human mesenchymal stem cells: a comparison between micromass and pellet culture systems. Biotechnol Lett 32, 1339, 2010.
    • (2010) Biotechnol Lett , vol.32 , pp. 1339
    • Zhang, L.1    Su, P.2    Xu, C.3    Yang, J.4    Yu, W.5    Huang, D.6
  • 32
    • 73349102553 scopus 로고    scopus 로고
    • Production of hyaline-like cartilage by bone marrow mesenchymal stem cells in a self-assembly model
    • Elder, S.H., Cooley, A.J., Jr., Borazjani, A., Sowell, B.L., To, H., and Tran, S.C. Production of hyaline-like cartilage by bone marrow mesenchymal stem cells in a self-assembly model. Tissue Eng Part A 15, 3025, 2009.
    • (2009) Tissue Eng Part A , vol.15 , pp. 3025
    • Elder, S.H.1    Cooley Jr., A.J.2    Borazjani, A.3    Sowell, B.L.4    To, H.5    Tran, S.C.6
  • 35
    • 84863588802 scopus 로고    scopus 로고
    • Transplantatation of scaffold-free spheroids composed of synoviumderived cells and chondrocytes for the treatment of cartilage defects of the knee
    • Lee, J.I., Sato, M., Kim, H.W., and Mochida, J. Transplantatation of scaffold-free spheroids composed of synoviumderived cells and chondrocytes for the treatment of cartilage defects of the knee. Eur Cell Mater 22, 275, 2011.
    • (2011) Eur Cell Mater , vol.22 , pp. 275
    • Lee, J.I.1    Sato, M.2    Kim, H.W.3    Mochida, J.4
  • 36
    • 0038784390 scopus 로고    scopus 로고
    • Collagen expression in tissue engineered cartilage of aged human articular chondrocytes in a rotating bioreactor
    • Marlovits, S., Tichy, B., Truppe, M., Gruber, D., and Schlegel, W. Collagen expression in tissue engineered cartilage of aged human articular chondrocytes in a rotating bioreactor. Int J Artif Organs 26, 319, 2003.
    • (2003) Int J Artif Organs , vol.26 , pp. 319
    • Marlovits, S.1    Tichy, B.2    Truppe, M.3    Gruber, D.4    Schlegel, W.5
  • 37
    • 84862958826 scopus 로고    scopus 로고
    • The use of micro-and nanospheres as functional components for bone tissue regeneration
    • Wang, H., Leeuwenburgh, S.C., Li, Y., and Jansen, J.A. The use of micro-and nanospheres as functional components for bone tissue regeneration. Tissue Eng Part B Rev 18, 24, 2012.
    • (2012) Tissue Eng Part B Rev , vol.18 , pp. 24
    • Wang, H.1    Leeuwenburgh, S.C.2    Li, Y.3    Jansen, J.A.4
  • 38
    • 5044224056 scopus 로고    scopus 로고
    • Delivery systems for small molecule drugs, proteins, and DNA: The neuroscience/biomaterial interface
    • Whittlesey, K.J., and Shea, L.D. Delivery systems for small molecule drugs, proteins, and DNA: the neuroscience/biomaterial interface. Exp Neurol 190, 1, 2004.
    • (2004) Exp Neurol , vol.190 , pp. 1
    • Whittlesey, K.J.1    Shea, L.D.2
  • 39
    • 0035907177 scopus 로고    scopus 로고
    • Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions
    • Berkland, C., Kim, K., and Pack, D.W. Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions. J Control Release 73, 59, 2001.
    • (2001) J Control Release , vol.73 , pp. 59
    • Berkland, C.1    Kim, K.2    Pack, D.W.3
  • 40
    • 60349122669 scopus 로고    scopus 로고
    • Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites
    • Park, H., Temenoff, J.S., Tabata, Y., Caplan, A.I., Raphael, R.M., Jansen, J.A., and Mikos, A.G. Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites. J Biomed Mater Res A 88, 889, 2009.
    • (2009) J Biomed Mater Res A , vol.88 , pp. 889
    • Park, H.1    Temenoff, J.S.2    Tabata, Y.3    Caplan, A.I.4    Raphael, R.M.5    Jansen, J.A.6    Mikos, A.G.7
  • 41
    • 70449709022 scopus 로고    scopus 로고
    • Microsphere-based scaffolds for cartilage tissue engineering: Using subcritical CO(2) as a sintering agent
    • Singh, M., Sandhu, B., Scurto, A., Berkland, C., and Detamore, M.S. Microsphere-based scaffolds for cartilage tissue engineering: using subcritical CO(2) as a sintering agent. Acta Biomater 6, 137, 2010.
    • (2010) Acta Biomater , vol.6 , pp. 137
    • Singh, M.1    Sandhu, B.2    Scurto, A.3    Berkland, C.4    Detamore, M.S.5
  • 42
    • 79955033758 scopus 로고    scopus 로고
    • Nanofibrous hollow microspheres self-assembled from star-shaped polymers as injectable cell carriers for knee repair
    • Liu, X., Jin, X., and Ma, P.X. Nanofibrous hollow microspheres self-assembled from star-shaped polymers as injectable cell carriers for knee repair. Nat Mater 10, 398, 2011.
    • (2011) Nat Mater , vol.10 , pp. 398
    • Liu, X.1    Jin, X.2    Ma, P.X.3
  • 43
    • 59649128010 scopus 로고    scopus 로고
    • Open macroporous poly(lactic-co-glycolic Acid) microspheres as an injectable scaffold for cartilage tissue engineering
    • Kang, S.W., La, W.G., and Kim, B.S. Open macroporous poly(lactic-co- glycolic Acid) microspheres as an injectable scaffold for cartilage tissue engineering. J Biomater Sci Polym Ed 20, 399, 2009.
    • (2009) J Biomater Sci Polym Ed , vol.20 , pp. 399
    • Kang, S.W.1    La, W.G.2    Kim, B.S.3
  • 44
    • 18244363868 scopus 로고    scopus 로고
    • Poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for cartilage tissue engineering
    • Kang, S.W., Jeon, O., and Kim, B.S. Poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for cartilage tissue engineering. Tissue Eng 11, 438, 2005.
    • (2005) Tissue Eng , vol.11 , pp. 438
    • Kang, S.W.1    Jeon, O.2    Kim, B.S.3
  • 45
    • 2942592380 scopus 로고    scopus 로고
    • A novel injectable approach for cartilage formation in vivo using PLG microspheres
    • Mercier, N.R., Costantino, H.R., Tracy, M.A., and Bonassar, L.J. A novel injectable approach for cartilage formation in vivo using PLG microspheres. Ann Biomed Eng 32, 418, 2004.
    • (2004) Ann Biomed Eng , vol.32 , pp. 418
    • Mercier, N.R.1    Costantino, H.R.2    Tracy, M.A.3    Bonassar, L.J.4
  • 46
    • 9644257017 scopus 로고    scopus 로고
    • Poly(lactide-co-glycolide) microspheres as a moldable scaffold for cartilage tissue engineering
    • Mercier, N.R., Costantino, H.R., Tracy, M.A., and Bonassar, L.J. Poly(lactide-co-glycolide) microspheres as a moldable scaffold for cartilage tissue engineering. Biomaterials 26, 1945, 2005.
    • (2005) Biomaterials , vol.26 , pp. 1945
    • Mercier, N.R.1    Costantino, H.R.2    Tracy, M.A.3    Bonassar, L.J.4
  • 47
    • 84858705261 scopus 로고    scopus 로고
    • Engineered cartilage via self-assembled hMSC sheets with incorporated biodegradable gelatin microspheres releasing transforming growth factor-beta1
    • Solorio, L.D., Vieregge, E.L., Dhami, C.D., Dang, P.N., and Alsberg, E. Engineered cartilage via self-assembled hMSC sheets with incorporated biodegradable gelatin microspheres releasing transforming growth factor-beta1. J Control Release 158, 224, 2012.
    • (2012) J Control Release , vol.158 , pp. 224
    • Solorio, L.D.1    Vieregge, E.L.2    Dhami, C.D.3    Dang, P.N.4    Alsberg, E.5
  • 48
    • 10044236578 scopus 로고    scopus 로고
    • Biodegradable PLGA microcarriers for injectable delivery of chondrocytes: Effect of surface modification on cell attachment and function
    • Chun, K.W., Yoo, H.S., Yoon, J.J., and Park, T.G. Biodegradable PLGA microcarriers for injectable delivery of chondrocytes: effect of surface modification on cell attachment and function. Biotechnol Prog 20, 1797, 2004.
    • (2004) Biotechnol Prog , vol.20 , pp. 1797
    • Chun, K.W.1    Yoo, H.S.2    Yoon, J.J.3    Park, T.G.4
  • 49
    • 79957690353 scopus 로고    scopus 로고
    • Preparation of stem cell aggregates with gelatin microspheres to enhance biological functions
    • Hayashi, K., and Tabata, Y. Preparation of stem cell aggregates with gelatin microspheres to enhance biological functions. Acta Biomater 7, 2797, 2011.
    • (2011) Acta Biomater , vol.7 , pp. 2797
    • Hayashi, K.1    Tabata, Y.2
  • 50
    • 34249935409 scopus 로고    scopus 로고
    • Injectable matrices and scaffolds for drug delivery in tissue engineering
    • Kretlow, J.D., Klouda, L., and Mikos, A.G. Injectable matrices and scaffolds for drug delivery in tissue engineering. Adv Drug Deliv Rev 59, 263, 2007.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 263
    • Kretlow, J.D.1    Klouda, L.2    Mikos, A.G.3
  • 51
  • 52
    • 33745575077 scopus 로고    scopus 로고
    • Microcarriers in the engineering of cartilage and bone
    • Malda, J., and Frondoza, C.G. Microcarriers in the engineering of cartilage and bone. Trends Biotechnol 24, 299, 2006.
    • (2006) Trends Biotechnol , vol.24 , pp. 299
    • Malda, J.1    Frondoza, C.G.2
  • 53
    • 77949345513 scopus 로고    scopus 로고
    • Efficient isolation and chondrogenic differentiation of adult mesenchymal stem cells with fibrin microbeads and micronized collagen sponges
    • Shainer, R., Gaberman, E., Levdansky, L., and Gorodetsky, R. Efficient isolation and chondrogenic differentiation of adult mesenchymal stem cells with fibrin microbeads and micronized collagen sponges. Regen Med 5, 255, 2010.
    • (2010) Regen Med , vol.5 , pp. 255
    • Shainer, R.1    Gaberman, E.2    Levdansky, L.3    Gorodetsky, R.4
  • 54
    • 33646909199 scopus 로고    scopus 로고
    • High-yield isolation, expansion, and differentiation of rat bone marrow-derived mesenchymal stem cells with fibrin microbeads
    • Zangi, L., Rivkin, R., Kassis, I., Levdansky, L., Marx, G., and Gorodetsky, R. High-yield isolation, expansion, and differentiation of rat bone marrow-derived mesenchymal stem cells with fibrin microbeads. Tissue Eng 12, 2343, 2006.
    • (2006) Tissue Eng , vol.12 , pp. 2343
    • Zangi, L.1    Rivkin, R.2    Kassis, I.3    Levdansky, L.4    Marx, G.5    Gorodetsky, R.6
  • 55
    • 20444470603 scopus 로고    scopus 로고
    • Collagencoated polylactide microspheres as chondrocyte microcarriers
    • Hong, Y., Gao, C., Xie, Y., Gong, Y., and Shen, J. Collagencoated polylactide microspheres as chondrocyte microcarriers. Biomaterials 26, 6305, 2005.
    • (2005) Biomaterials , vol.26 , pp. 6305
    • Hong, Y.1    Gao, C.2    Xie, Y.3    Gong, Y.4    Shen, J.5
  • 56
    • 50649085438 scopus 로고    scopus 로고
    • Chitosan modified poly(L-lactide) microspheres as cell microcarriers for cartilage tissue engineering
    • Lao, L., Tan, H., Wang, Y., and Gao, C. Chitosan modified poly(L-lactide) microspheres as cell microcarriers for cartilage tissue engineering. Colloids Surf B Biointerfaces 66, 218, 2008.
    • (2008) Colloids Surf B Biointerfaces , vol.66 , pp. 218
    • Lao, L.1    Tan, H.2    Wang, Y.3    Gao, C.4
  • 58
    • 43649096860 scopus 로고    scopus 로고
    • Highly open porous biodegradable microcarriers: In vitro cultivation of chondrocytes for injectable delivery
    • Chung, H.J., Kim, I.K., Kim, T.G., and Park, T.G. Highly open porous biodegradable microcarriers: in vitro cultivation of chondrocytes for injectable delivery. Tissue Eng Part A 14, 607, 2008.
    • (2008) Tissue Eng Part A , vol.14 , pp. 607
    • Chung, H.J.1    Kim, I.K.2    Kim, T.G.3    Park, T.G.4
  • 59
    • 33747503574 scopus 로고    scopus 로고
    • The use of poly(l-lactide) and RGD modified microspheres as cell carriers in a flow intermittency bioreactor for tissue engineering cartilage
    • Chen, R., Curran, S.J., Curran, J.M., and Hunt, J.A. The use of poly(l-lactide) and RGD modified microspheres as cell carriers in a flow intermittency bioreactor for tissue engineering cartilage. Biomaterials 27, 4453, 2006.
    • (2006) Biomaterials , vol.27 , pp. 4453
    • Chen, R.1    Curran, S.J.2    Curran, J.M.3    Hunt, J.A.4
  • 60
    • 78149468311 scopus 로고    scopus 로고
    • Modulating and modeling aggregation of cell-seeded microcarriers in stirred culture system for macrotissue engineering
    • Mei, Y., Luo, H., Tang, Q., Ye, Z., Zhou, Y., and Tan, W.S. Modulating and modeling aggregation of cell-seeded microcarriers in stirred culture system for macrotissue engineering. J Biotechnol 150, 438, 2010.
    • (2010) J Biotechnol , vol.150 , pp. 438
    • Mei, Y.1    Luo, H.2    Tang, Q.3    Ye, Z.4    Zhou, Y.5    Tan, W.S.6
  • 61
    • 0030152203 scopus 로고    scopus 로고
    • Human chondrocytes proliferate and produce matrix components in microcarrier suspension culture
    • Frondoza, C., Sohrabi, A., and Hungerford, D. Human chondrocytes proliferate and produce matrix components in microcarrier suspension culture. Biomaterials 17, 879, 1996.
    • (1996) Biomaterials , vol.17 , pp. 879
    • Frondoza, C.1    Sohrabi, A.2    Hungerford, D.3
  • 62
    • 32144434552 scopus 로고    scopus 로고
    • Expansion of chondroprogenitor cells on macroporous microcarriers as an alternative to conventional monolayer systems
    • Melero-Martin, J.M., Dowling, M.A., Smith, M., and Al-Rubeai, M. Expansion of chondroprogenitor cells on macroporous microcarriers as an alternative to conventional monolayer systems. Biomaterials 27, 2970, 2006.
    • (2006) Biomaterials , vol.27 , pp. 2970
    • Melero-Martin, J.M.1    Dowling, M.A.2    Smith, M.3    Al-Rubeai, M.4
  • 63
    • 70350721525 scopus 로고    scopus 로고
    • Human articular chondrocytes on macroporous gelatin microcarriers form structurally stable constructs with blood-derived biological glues in vitro
    • Pettersson, S., Wettero, J., Tengvall, P., and Kratz, G. Human articular chondrocytes on macroporous gelatin microcarriers form structurally stable constructs with blood-derived biological glues in vitro. J Tissue Eng Regen Med 3, 450, 2009.
    • (2009) J Tissue Eng Regen Med , vol.3 , pp. 450
    • Pettersson, S.1    Wettero, J.2    Tengvall, P.3    Kratz, G.4
  • 64
    • 33644874153 scopus 로고    scopus 로고
    • High-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells
    • Penick, K.J., Solchaga, L.A., and Welter, J.F. High-throughput aggregate culture system to assess the chondrogenic potential of mesenchymal stem cells. Biotechniques 39, 687, 2005.
    • (2005) Biotechniques , vol.39 , pp. 687
    • Penick, K.J.1    Solchaga, L.A.2    Welter, J.F.3
  • 65
    • 41949115978 scopus 로고    scopus 로고
    • Gelatin microspheres containing TGF-beta3 enhance the chondrogenesis of mesenchymal stem cells in modified pellet culture
    • Fan, H., Zhang, C., Li, J., Bi, L., Qin, L., Wu, H., and Hu, Y. Gelatin microspheres containing TGF-beta3 enhance the chondrogenesis of mesenchymal stem cells in modified pellet culture. Biomacromolecules 9, 927, 2008.
    • (2008) Biomacromolecules , vol.9 , pp. 927
    • Fan, H.1    Zhang, C.2    Li, J.3    Bi, L.4    Qin, L.5    Wu, H.6    Hu, Y.7
  • 66
    • 75749158166 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human mesenchymal stem cell aggregates via controlled release of TGF-beta1 from incorporated polymer microspheres
    • Solorio, L.D., Fu, A.S., Hernandez-Irizarry, R., and Alsberg, E. Chondrogenic differentiation of human mesenchymal stem cell aggregates via controlled release of TGF-beta1 from incorporated polymer microspheres. J Biomed Mater Res A 92, 1139, 2010.
    • (2010) J Biomed Mater Res A , vol.92 , pp. 1139
    • Solorio, L.D.1    Fu, A.S.2    Hernandez-Irizarry, R.3    Alsberg, E.4
  • 67
    • 84872104377 scopus 로고    scopus 로고
    • Spatiotemporal regulation of chondrogenic differentiation with controlled delivery of transforming growth factor-b1 from gelatin microspheres in mesenchymal stem cell aggregates
    • Solorio, L.D., Dhami, C.D., Dang, P.N., Vieregge, E.L., and Alsberg, E. Spatiotemporal regulation of chondrogenic differentiation with controlled delivery of transforming growth factor-b1 from gelatin microspheres in mesenchymal stem cell aggregates. Stem Cells Translational Med 1, 632, 2012.
    • (2012) Stem Cells Translational Med , vol.1 , pp. 632
    • Solorio, L.D.1    Dhami, C.D.2    Dang, P.N.3    Vieregge, E.L.4    Alsberg, E.5
  • 68
    • 73449101414 scopus 로고    scopus 로고
    • Cartilage regeneration using adipose-derived stem cells and the controlledreleased hybrid microspheres
    • Han, Y., Wei, Y., Wang, S., and Song, Y. Cartilage regeneration using adipose-derived stem cells and the controlledreleased hybrid microspheres. Joint Bone Spine 77, 27, 2010.
    • (2010) Joint Bone Spine , vol.77 , pp. 27
    • Han, Y.1    Wei, Y.2    Wang, S.3    Song, Y.4
  • 69
    • 70349498418 scopus 로고    scopus 로고
    • Enhanced chondrogenesis of adipose-derived stem cells by the controlled release of transforming growth factor-beta1 from hybrid microspheres
    • Han, Y., Wei, Y., Wang, S., and Song, Y. Enhanced chondrogenesis of adipose-derived stem cells by the controlled release of transforming growth factor-beta1 from hybrid microspheres. Gerontology 55, 592, 2009.
    • (2009) Gerontology , vol.55 , pp. 592
    • Han, Y.1    Wei, Y.2    Wang, S.3    Song, Y.4
  • 71
    • 39749185584 scopus 로고    scopus 로고
    • The use of mesenchymal stem cells for chondrogenesis
    • Pelttari, K., Steck, E., and Richter, W. The use of mesenchymal stem cells for chondrogenesis. Injury 39 Suppl 1, S58, 2008.
    • (2008) Injury , vol.39 , Issue.SUPPL. 1
    • Pelttari, K.1    Steck, E.2    Richter, W.3
  • 72
    • 33750321974 scopus 로고    scopus 로고
    • Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice
    • Pelttari, K., Winter, A., Steck, E., Goetzke, K., Hennig, T., Ochs, B.G., Aigner, T., and Richter, W. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 54, 3254, 2006.
    • (2006) Arthritis Rheum , vol.54 , pp. 3254
    • Pelttari, K.1    Winter, A.2    Steck, E.3    Goetzke, K.4    Hennig, T.5    Ochs, B.G.6    Aigner, T.7    Richter, W.8
  • 73
    • 84876222555 scopus 로고    scopus 로고
    • Driving cartilage formation in high-density human adipose-derived stem cell aggregate and sheet constructs without exogenous growth factor delivery
    • submitted Sept.
    • Dang, P.N., Solorio, L.D., and Alsberg, E. Driving cartilage formation in high-density human adipose-derived stem cell aggregate and sheet constructs without exogenous growth factor delivery. (Tissue Eng Part A, submitted Sept. 2012).
    • (2012) Tissue Eng Part A
    • Dang, P.N.1    Solorio, L.D.2    Alsberg, E.3
  • 74
    • 52649153073 scopus 로고    scopus 로고
    • PLGA microsphere construct coated with TGF-beta 3 loaded nanoparticles for neocartilage formation
    • Park, J.S., Park, K., Woo, D.G., Yang, H.N., Chung, H.M., and Park, K.H. PLGA microsphere construct coated with TGF-beta 3 loaded nanoparticles for neocartilage formation. Biomacromolecules 9, 2162, 2008.
    • (2008) Biomacromolecules , vol.9 , pp. 2162
    • Park, J.S.1    Park, K.2    Woo, D.G.3    Yang, H.N.4    Chung, H.M.5    Park, K.H.6
  • 75
    • 67749130621 scopus 로고    scopus 로고
    • Determination of dual delivery for stem cell differentiation using dexamethasone and TGF-beta3 in/on polymeric microspheres
    • Park, J.S., Na, K., Woo, D.G., Yang, H.N., and Park, K.H. Determination of dual delivery for stem cell differentiation using dexamethasone and TGF-beta3 in/on polymeric microspheres. Biomaterials 30, 4796, 2009.
    • (2009) Biomaterials , vol.30 , pp. 4796
    • Park, J.S.1    Na, K.2    Woo, D.G.3    Yang, H.N.4    Park, K.H.5
  • 76
    • 78349307001 scopus 로고    scopus 로고
    • The promotion of chondrogenesis, osteogenesis, and adipogenesis of human mesenchymal stem cells by multiple growth factors incorporated into nanosphere-coated microspheres
    • Park, J.S., Yang, H.N., Woo, D.G., Jeon, S.Y., and Park, K.H. The promotion of chondrogenesis, osteogenesis, and adipogenesis of human mesenchymal stem cells by multiple growth factors incorporated into nanosphere-coated microspheres. Biomaterials 32, 28, 2011.
    • (2011) Biomaterials , vol.32 , pp. 28
    • Park, J.S.1    Yang, H.N.2    Woo, D.G.3    Jeon, S.Y.4    Park, K.H.5
  • 77
    • 77950279580 scopus 로고    scopus 로고
    • In vitro proliferation and chondrogenic differentiation of rat bone marrow stem cells cultured with gelatin hydrogel microspheres for TGFbeta1 release
    • Ogawa, T., Akazawa, T., and Tabata, Y. In vitro proliferation and chondrogenic differentiation of rat bone marrow stem cells cultured with gelatin hydrogel microspheres for TGFbeta1 release. J Biomater Sci Polym Ed 21, 609, 2010.
    • (2010) J Biomater Sci Polym Ed , vol.21 , pp. 609
    • Ogawa, T.1    Akazawa, T.2    Tabata, Y.3
  • 78
    • 0029583775 scopus 로고
    • The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules
    • Muir, H. The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules. Bioessays 17, 1039, 1995.
    • (1995) Bioessays , vol.17 , pp. 1039
    • Muir, H.1
  • 79
    • 34447333926 scopus 로고    scopus 로고
    • Cartilaginous ECM component-modification of the microbead culture system for chondrogenic differentiation of mesenchymal stem cells
    • Wu, Y.N., Yang, Z., Hui, J.H., Ouyang, H.W., and Lee, E.H. Cartilaginous ECM component-modification of the microbead culture system for chondrogenic differentiation of mesenchymal stem cells. Biomaterials 28, 4056, 2007.
    • (2007) Biomaterials , vol.28 , pp. 4056
    • Wu, Y.N.1    Yang, Z.2    Hui, J.H.3    Ouyang, H.W.4    Lee, E.H.5
  • 80
    • 80052967002 scopus 로고    scopus 로고
    • Changes of chondrocyte expression profiles in human MSC aggregates in the presence of PEG microspheres and TGF-beta3
    • Ravindran, S., Roam, J.L., Nguyen, P.K., Hering, T.M., Elbert, D.L., and McAlinden, A. Changes of chondrocyte expression profiles in human MSC aggregates in the presence of PEG microspheres and TGF-beta3. Biomaterials 32, 8436, 2011.
    • (2011) Biomaterials , vol.32 , pp. 8436
    • Ravindran, S.1    Roam, J.L.2    Nguyen, P.K.3    Hering, T.M.4    Elbert, D.L.5    McAlinden, A.6
  • 81
    • 77953960598 scopus 로고    scopus 로고
    • The role of pharmacologically active microcarriers releasing TGF-beta3 in cartilage formation in vivo by mesenchymal stem cells
    • Bouffi, C., Thomas, O., Bony, C., Giteau, A., Venier-Julienne, M.C., Jorgensen, C., Montero-Menei, C., and Noel, D. The role of pharmacologically active microcarriers releasing TGF-beta3 in cartilage formation in vivo by mesenchymal stem cells. Biomaterials 31, 6485, 2010.
    • (2010) Biomaterials , vol.31 , pp. 6485
    • Bouffi, C.1    Thomas, O.2    Bony, C.3    Giteau, A.4    Venier-Julienne, M.C.5    Jorgensen, C.6    Montero-Menei, C.7    Noel, D.8
  • 82
    • 63049121616 scopus 로고    scopus 로고
    • Modular tissue engineering: Engineering biological tissues from the bottom up
    • Nichol, J.W., and Khademhosseini, A. Modular tissue engineering: engineering biological tissues from the bottom up. Soft Matter 5, 1312, 2009.
    • (2009) Soft Matter , vol.5 , pp. 1312
    • Nichol, J.W.1    Khademhosseini, A.2
  • 83
    • 80052966768 scopus 로고    scopus 로고
    • Bottom-up tissue engineering
    • Elbert, D.L. Bottom-up tissue engineering. Curr Opin Biotechnol 22, 674, 2011.
    • (2011) Curr Opin Biotechnol , vol.22 , pp. 674
    • Elbert, D.L.1
  • 84
    • 0034789414 scopus 로고    scopus 로고
    • Transplantation of brain cells assembled around a programmable synthetic microenvironment
    • Mahoney, M.J., and Saltzman, W.M. Transplantation of brain cells assembled around a programmable synthetic microenvironment. Nat Biotechnol 19, 934, 2001.
    • (2001) Nat Biotechnol , vol.19 , pp. 934
    • Mahoney, M.J.1    Saltzman, W.M.2
  • 85
    • 80051546692 scopus 로고    scopus 로고
    • A modular approach to the engineering of a centimeter-sized bone tissue construct with human amniotic mesenchymal stem cells-laden microcarriers
    • Chen, M., Wang, X., Ye, Z., Zhang, Y., Zhou, Y., and Tan, W.S. A modular approach to the engineering of a centimeter-sized bone tissue construct with human amniotic mesenchymal stem cells-laden microcarriers. Biomaterials 32, 7532, 2011.
    • (2011) Biomaterials , vol.32 , pp. 7532
    • Chen, M.1    Wang, X.2    Ye, Z.3    Zhang, Y.4    Zhou, Y.5    Tan, W.S.6
  • 86
    • 60849103067 scopus 로고    scopus 로고
    • Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules
    • Carpenedo, R.L., Bratt-Leal, A.M., Marklein, R.A., Seaman, S.A., Bowen, N.J., McDonald, J.F., and McDevitt, T.C. Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules. Biomaterials 30, 2507, 2009.
    • (2009) Biomaterials , vol.30 , pp. 2507
    • Carpenedo, R.L.1    Bratt-Leal, A.M.2    Marklein, R.A.3    Seaman, S.A.4    Bowen, N.J.5    McDonald, J.F.6    McDevitt, T.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.