Highly open porous biodegradable microcarriers: In vitro cultivation of chondrocytes for injectable delivery

Tissue Engineering - Part A.

Volumn 14, Issue 5, 2008, Pages 607-615

  Chung, Hyun Jung ^a   Kim, In Kyoung ^a   Kim, Taek Gyoung ^a   Park, Tae Gwan ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADABILITY; CELL CULTURE; CELL GROWTH; DNA; SCAFFOLDS; TISSUE ENGINEERING;

CELL CULTIVATION; INJECTABLE DELIVERY; MICROCARRIERS; POLY(LACTIC-CO-GLYCOLIC ACID) (PLGA); TISSUE REGENERATION;

POROUS MATERIALS;

COLLAGEN; DNA; GLYCOSAMINOGLYCAN; MICROSPHERE; POLYGLACTIN; WATER OIL CREAM;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; BIODEGRADABILITY; CARTILAGE CELL; CATTLE; CELL CULTURE; CELL PROLIFERATION; CELL THERAPY; CONTROLLED STUDY; FOAM; GAS; MICROCARRIER CULTURE; MONOLAYER CULTURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TISSUE REGENERATION;

BOVINAE;

EID: 43649096860     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/tea.2007.0263     Document Type: Article

References (64)

1. Freed, L.E., Vunjak-Novakovic, G., Biron, R.J., Eagles, D.B., Lesnoy, D.C., Barlow, S.K., and Langer, R. Biodegradable polymer scaffolds for tissue engineering. Nat. Biotechnol. 12, 689, 1994.
2. Yang, S., Leong, K., Du, Z., and Chua, C. The design of scaffolds for use in tissue engineering. Part I. Traditional factors. Tissue Eng. 7, 679, 2001.
3. Yoon, J.J. and Park, T.G. Degradation behaviors of biodegradable macroporous scaffolds prepared by gas foaming of effervescent salts. J. Biomed. Mater. Res. 55, 401, 2001.
4. Mooney, D.J., Baldwin, D.F., Suh, N.P., Vacanti, J.P., and Langer, R. Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvent. Biomaterials 17, 1417, 1996.
5. Harris, L.D., Kim, B., and Mooney, D.J. Open pore biodegradable matrices formed with gas foaming. J. Biomed. Mater. Res. 42, 396, 1998.
6. Hoffman, A.S. Hydrogels for biomedical applications. Adv. Drug. Deliv. Rev. 43, 3, 2002.
7. Drury, J.L. and Mooney, D.J. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 24, 4337, 2003.
8. Mercier, N.R., Costantino, H.R., Tracy, M.A., and Bonassar, L.J. A novel injectable approach for cartilage formation in vivo using PLG microspheres. Ann. Biomed. Eng. 32, 418, 2004.
9. Kang, S., Jeon, O., and Kim, B. Poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for cartilage tissue engineering. Tissue Eng. 11, 438, 2005.
10. Chun, K.W., Yoo, H.S., Yoon, J.J., and Park, T.G. Biodegradable PLGA microcarriers for injectable delivery of chondrocytes: effect of surface modification on cell attachment and function. Biotechnol. Prog. 20, 1797, 2004.
11. Thissen, H., Chang, K.Y., Tebb, T.A., Tsai, W.B., Glattauer, V., Ramshaw, J.A.M., and Werkmeister, J.A. Synthetic biodegradable microparticles for articular cartilage tissue engineering. J. Biomed. Mater. Res. 77A, 590, 2006.
12. Hong, Y., Gao, C., Xie, Y., Gong, Y., and Shen, J. Collagencoated polylactide microspheres as chondrocyte microcarriers. Biomaterials 26, 6305, 2005.
13. Botchwey, E. A., Pollack, S. R., Levine, E. M., and Laurencin, C. T. Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system. J. Biomed. Mater. Res. 55, 242, 2001.
14. Li, K., Wang, Y., Miao, Z., Xu, D., Tang, Y., and Feng, M. Chitosan/gelatin composite microcarrier for hepatocyte culture. Biotechnol. Lett. 26, 879, 2004.
15. Frauenschuh, S., Reichmann, E., Ibold, Y., Goetz, P.M., Sittinger, M., and J. Ringe, A microcarrier-based cultivation system for expansion of primary mesenchymal stem cells, Biotechnol. Prog. 23, 187, 2007.
16. Kim, T.K., Yoon, J.J., Lee, D.S., and Park, T.G. Gas foamed open porous biodegradable polymeric microspheres. Biomaterials 27, 152, 2006.
17. Klagsbrun, M. Large-scale preparation of chondrocytes. Methods Enzymol. 58, 560, 1979.
18. Curran, S.J., Chen, R., Curran, J.M., and Hunt, J.A. Expansion of human chondrocytes in an intermittent stirred flow bioreactor, using modified biodegradable microspheres. Tissue Eng. 11, 1312, 2005.
19. Kim, Y., Sah, R.L.Y., Doong, J.H., and Grodzinsky, A.J. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal. Biochem. 174, 168, 1988.
20. Farndale, R.W., Buttle, D.J., and Barrett, A.J. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim. Biophys. Acta. 883, 173, 1986.
21. Reddy, G.K. and Enwemeka, C.S. A simplified method for the analysis of hydroxyproline in biological tissues. Clin. Biochem. 29, 225, 1996.
22. Kim, H.K., Chung, H.J., and Park, T.G. Biodegradable polymeric microspheres with ''open/closed'' pores for sustained release of human growth hormone. J. Control. Release 112, 167, 2006.
23. Kato, D., Takeuchi, M., Sakurai, T., Furukawa, S., Mizokami, H., Sakata, M., Hirayama, C., and Kunitake, M. The design of polymer microcarrier surfaces for enhanced cell growth. Biomaterials 24, 4253, 2003.
24. Frondoza, C., Sohrabi, A., and Hungerford, D. Human chondrocytes proliferate and produce matrix components in microcarrier suspension culture. Biomaterials 17, 879, 1996.
25. Ng, Y.C., Berry, J.M., and Butler, M. Optimization of physical parameters for cell attachment and growth on macroporous microcarriers. Biotechnol. Bioeng. 50, 627, 1996.
26. Shiragami, N., Hakoda, M., Enomoto, A., and Hoshino, T. Hydrodynamic effect on cell attachment to microcarriers at initial stage of microcarrier culture. Bioprocess Eng. 16, 399, 1997.
27. Croughan, M.S., Hamel, J., and Wang, D.I.C. Hydrodynamic effects on animal cells grown in microcarrier cultures. Biotechnol. Bioeng. 29, 130, 1987.
28. Pollack, S.R., Meaney, D.F., Levine, E.M., Litt, M., and Johnston, E.D. Numerical model and experimental validation of microcarrier motion in a rotating bioreactor, Tissue Eng. 6, 519, 2000.
29. Jianjun Fang, Yun Zhang, Shifeng Yan, Zhiwen Liu, Shiming He, Lei Cui, Jingbo Yin. 2014. Poly(l-glutamic acid)/chitosan polyelectrolyte complex porous microspheres as cell microcarriers for cartilage regeneration. Acta Biomaterialia 10:1, 276-288. [CrossRef]
30. David Antonio Cantu, W. John Kao. 2013. Combinatorial Biomatrix/Cell-Based Therapies for Restoration of Host Tissue Architecture and Function. Advanced Healthcare Materials 2:12, 1544-1563. [CrossRef]
31. Allen Kuan-Liang Chen, Shaul Reuveny, Steve Kah Weng Oh. 2013. Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: Achievements and future direction. Biotechnology Advances 31:7, 1032-1046. [CrossRef]
32. Tae-Kyoung Ryu, Myoung-Jin Oh, Seung-Kwan Moon, Dong-Hyun Paik, Sung-Eun Kim, Jong-Hoon Park, Sung-Wook Choi. 2013. Uniform Tricalcium Phosphate Beads with an Open Porous Structure for Tissue Engineering. Colloids and Surfaces B: Biointerfaces . [CrossRef]
33. Loran D. Solorio, Eran L. Vieregge, Chirag D. Dhami, Eben Alsberg. 2013. High-Density Cell Systems Incorporating Polymer Microspheres as Microenvironmental Regulators in Engineered Cartilage Tissues. Tissue Engineering Part B: Reviews 19:3, 209-220. [Abstract] [Full Text HTML] [Full Text PDF] [Full Text PDF with Links]
34. Sarah E. Bulman, Valerie Barron, Cynthia M. Coleman, Frank Barry. 2013. Enhancing the Mesenchymal Stem Cell Therapeutic Response: Cell Localization and Support for Cartilage Repair. Tissue Engineering Part B: Reviews 19:1, 58-68. [Abstract] [Full Text HTML] [Full Text PDF] [Full Text PDF with Links]
35. Weiqing Zhou, Guanghui MaMicrospheres for Cell Culture 49-83. [CrossRef]
36. Zhengrong Yu, Tianyue Zhu, Chunde Li, Xudong Shi, Xianyi Liu, Xin Yang, Haolin Sun. 2012. Improvement of intertrochanteric bone quality in osteoporotic female rats after injection of polylactic acid-polyglycolic acid copolymer/collagen type I microspheres combined with bone mesenchymal stem cells. International Orthopaedics 36:10, 2163-2171. [CrossRef]
37. Byeong Jin Jeon, Seo Young Jeong, Ahn Na Koo, Byung-Chul Kim, Yu-Shik Hwang, Sang Cheon Lee. 2012. Fabrication of porous PLGA microspheres with BMP-2 releasing polyphosphate-functionalized nano-hydroxyapatite for enhanced bone regeneration. Macromolecular Research 20:7, 715-724. [CrossRef]
38. Chun TAO, Yan CHEN, Yan-qiang ZHONG. 2012. RGD-modified polylactide-co-glycolic acid tissue engineering scaffolds for bone regeneration: an advance. Academic Journal of Second Military Medical University 32:1, 95-98. [CrossRef]
39. Petr Knotek, Miloslav Pouzar, Matej Buzgo, Barbora Krizkova, Milan Vlcek, Andrea Mickova, Martin Plencner, Jakub Navesnik, Evzen Amler, Petr Belina. 2012. Cryogenic grinding of electrospun poly-e-caprolactone mesh submerged in liquid media. Materials Science and Engineering: C . [CrossRef]
40. Taek Gyoung Kim, Heungsoo Shin, Dong Woo Lim. 2012. Biomimetic Scaffolds for Tissue Engineering. Advanced Functional Materials n/a-n/a. [CrossRef]
41. Allison E.B. Turner, Lauren E. Flynn. 2012. Design and Characterization of Tissue-Specific Extracellular Matrix-Derived Microcarriers. Tissue Engineering Part C: Methods 18:3, 186-197. [Abstract] [Full Text HTML] [Full Text PDF] [Full Text PDF with Links] [Supplemental Material]
42. Chieh-Cheng Huang, Hao-Ji Wei, Yi-Chun Yeh, Jiun-Jie Wang, Wei-Wen Lin, Ting-Yin Lee, Shiaw-Min Hwang, Sung-Wook Choi, Younan Xia, Yen Chang, Hsing-Wen Sung. 2012. Injectable PLGA porous beads cellularized by hAFSCs for cellular cardiomyoplasty. Biomaterials . [CrossRef]
43. Riccardo Levato, Miguel A. Mateos-Timoneda, Josep A. Planell. 2012. Preparation of Biodegradable Polylactide Microparticles via a Biocompatible Procedure. Macromolecular Bioscience n/a-n/a. [CrossRef]
44. Sung-Wook Choi, Yu Zhang, Yi-Chun Yeh, A. Lake Wooten, Younan Xia. 2012. Biodegradable porous beads and their potential applications in regenerative medicine. Journal of Materials Chemistry 22:23, 11442. [CrossRef]
45. Sofia Pettersson, Jonas Wetterö, Pentti Tengvall, Gunnar Kratz. 2011. Cell expansion of human articular chondrocytes on macroporous gelatine scaffolds-impact of microcarrier selection on cell proliferation. Biomedical Materials 6:6, 065001. [CrossRef]
46. Kristina Ambrosch, Markus Manhardt, Tina Loth, Ricardo Bernhardt, Michaela Schulz-Siegmund, Michael C. Hacker. 2011. Open porous microscaffolds for cellular and tissue engineering by lipid templating. Acta Biomaterialia . [CrossRef]
47. Xudong SHI, Lei SUN, Zhihua GAN. 2011. FORMATION MECHANISM OF SOLVENT-INDUCED POROUS PLA MICROSPHERES. Acta Polymerica Sinica 011:8, 866-873. [CrossRef]
48. Yanhong Wen, Monica Ramos Gallego, Lene Feldskov Nielsen, Lene Jorgensen, Hanne Everland, Eva Horn Møller, Hanne Mørck Nielsen. 2011. Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds. Journal of Controlled Release . [CrossRef]
49. Bret D. Ulery, Lakshmi S. Nair, Cato T. Laurencin. 2011. Biomedical applications of biodegradable polymers. Journal of Polymer Science Part B: Polymer Physics 49:12, 832-864. [CrossRef]
50. Xudong Shi, Jian Jiang, Lei Sun, Zhihua Gan. 2011. Hydrolysis and biomineralization of porous PLA microspheres and their influence on cell growth. Colloids and Surfaces B: Biointerfaces 85:1, 73-80. [CrossRef]
51. Yella Martin, Mohamed Eldardiri, Diana J. Lawrence-Watt, Justin R. Sharpe. 2011. Microcarriers and Their Potential in Tissue Regeneration. Tissue Engineering Part B: Reviews 17:1, 71-80. [Abstract] [Full Text HTML] [Full Text PDF] [Full Text PDF with Links]
52. Mariana B. Oliveira, João F. Mano. 2011. Polymer-based microparticles in tissue engineering and regenerative medicine. Biotechnology Progress n/a-n/a. [CrossRef]
53. Kalpna Garkhal, Anupama Mittal, Shalini Verma, Neeraj Kumar. 2011. P-15 functionalized porous microspheres as biomimetic habitats for bone tissue engineering applications. Polymers for Advanced Technologies 22:1, 190-198. [CrossRef]
54. Rainer J. Egli, Ellen Wernike, Sibylle Grad, Reto Luginbü hlPhysiological Cartilage Tissue Engineering 289, 37-87. [CrossRef]
55. Hyun Jung Chung, Jin Sup Jung, Tae Gwan Park. 2011. Fabrication of Adipose-Derived Mesenchymal Stem Cell Aggregates using Biodegradable Porous Microspheres for Injectable Adipose Tissue Regeneration. Journal of Biomaterials Science, Polymer Edition 22:1-3, 107-122. [CrossRef]
56. Hyukjin Lee, Hyun Jung Chung, Tae Gwan ParkDesign Principles in Biomaterials and Scaffolds 543-556. [CrossRef]
57. Anupama Mittal, Poonam Negi, Kalpna Garkhal, Shalini Verma, Neeraj Kumar. 2010. Integration of porosity and biofunctionalization to form a 3D scaffold: cell culture studies and in vitro degradation. Biomedical Materials 5:4, 045001. [CrossRef]
58. Nualchai Kotsaeng, Jesada Karnchanajindanun, Yodthong Baimark. 2010. Chitosan Microparticles Prepared by the Simple Emulsification-Diffusion Method. Particulate Science and Technology 28:4, 369-378. [CrossRef]
59. Sung-Wook Choi, Yi-Chun Yeh, Yu Zhang, Hsing-Wen Sung, Younan Xia. 2010. Uniform Beads with Controllable Pore Sizes for Biomedical Applications. Small 6:14, 1492-1498. [CrossRef]
60. Yodthong Baimark. 2009. Porous microspheres of methoxy poly(ethylene glycol)-b-poly(?-caprolactone-co-d,l-lactide) prepared by a melt dispersion method. Polymer 50:20, 4761-4767. [CrossRef]
61. Sofia Pettersson, Jonas Wetterö, Pentti Tengvall, Gunnar Kratz. 2009. Human articular chondrocytes on macroporous gelatin microcarriers form structurally stable constructs with blood-derived biological glues in vitro. Journal of Tissue Engineering and Regenerative Medicine 3:6, 450-460. [CrossRef]
62. Seok-Jung Hong, Hye-Sun Yu, Hae-Won Kim. 2009. Tissue Engineering Polymeric Microcarriers with Macroporous Morphology and Bone-Bioactive Surface. Macromolecular Bioscience 9:7, 639-645. [CrossRef]
63. Hyun Jung Chung, Tae Gwan Park. 2009. Injectable Cellular Aggregates Prepared from Biodegradable Porous Microspheres for Adipose Tissue Engineering. Tissue Engineering Part A 15:6, 1391-1400. [Abstract] [Full Text HTML] [Full Text PDF] [Full Text PDF with Links]
64. Xuetao Shi, Yingjun Wang, Li Ren, Wei Huang, Dong-An Wang. 2009. A protein/antibiotic releasing poly(lactic-co-glycolic acid)/lecithin scaffold for bone repair applications. International Journal of Pharmaceutics 373:1-2, 85-92. [CrossRef]