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Volumn 8, Issue 4, 2013, Pages

The C-Type Lectin of the Aggrecan G3 Domain Activates Complement

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; AGGRECAN G3; C TYPE LECTIN; COMPLEMENT; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT CONTROL PROTEIN; COMPLEMENT INHIBITOR; COMPLEMENT INHIBITOR FH; CORE PROTEIN; LECTIN; UNCLASSIFIED DRUG;

EID: 84876176589     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061407     Document Type: Article
Times cited : (30)

References (44)
  • 1
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • Ricklin D, Hajishengallis G, Yang K, Lambris JD, (2010) Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11: 785-797.
    • (2010) Nat Immunol , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 2
    • 60349127531 scopus 로고    scopus 로고
    • Complement activation and inhibition: a delicate balance
    • Sjoberg AP, Trouw LA, Blom AM, (2009) Complement activation and inhibition: a delicate balance. Trends Immunol 30: 83-90.
    • (2009) Trends Immunol , vol.30 , pp. 83-90
    • Sjoberg, A.P.1    Trouw, L.A.2    Blom, A.M.3
  • 3
    • 35649005450 scopus 로고    scopus 로고
    • Rheumatoid arthritis and the complement system
    • Okroj M, Heinegard D, Holmdahl R, Blom AM, (2007) Rheumatoid arthritis and the complement system. Ann Med 39: 517-530.
    • (2007) Ann Med , vol.39 , pp. 517-530
    • Okroj, M.1    Heinegard, D.2    Holmdahl, R.3    Blom, A.M.4
  • 4
    • 77954312095 scopus 로고    scopus 로고
    • New insights into the molecular mechanisms of classical complement activation
    • Kojouharova M, Reid K, Gadjeva M, (2010) New insights into the molecular mechanisms of classical complement activation. Mol Immunol 47: 2154-2160.
    • (2010) Mol Immunol , vol.47 , pp. 2154-2160
    • Kojouharova, M.1    Reid, K.2    Gadjeva, M.3
  • 5
    • 25444512040 scopus 로고    scopus 로고
    • Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins
    • Groeneveld TW, Oroszlan M, Owens RT, Faber-Krol MC, Bakker AC, et al. (2005) Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol 175: 4715-4723.
    • (2005) J Immunol , vol.175 , pp. 4715-4723
    • Groeneveld, T.W.1    Oroszlan, M.2    Owens, R.T.3    Faber-Krol, M.C.4    Bakker, A.C.5
  • 6
    • 59249103181 scopus 로고    scopus 로고
    • Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation
    • Sjoberg AP, Manderson GA, Morgelin M, Day AJ, Heinegard D, et al. (2009) Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation. Mol Immunol 46: 830-839.
    • (2009) Mol Immunol , vol.46 , pp. 830-839
    • Sjoberg, A.P.1    Manderson, G.A.2    Morgelin, M.3    Day, A.J.4    Heinegard, D.5
  • 8
    • 0021970584 scopus 로고
    • The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane
    • Bohnsack JF, Tenner AJ, Laurie GW, Kleinman HK, Martin GR, et al. (1985) The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane. Proc Natl Acad Sci USA 82: 3824-3828.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 3824-3828
    • Bohnsack, J.F.1    Tenner, A.J.2    Laurie, G.W.3    Kleinman, H.K.4    Martin, G.R.5
  • 9
    • 25444482114 scopus 로고    scopus 로고
    • The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q
    • Sjoberg A, Onnerfjord P, Morgelin M, Heinegard D, Blom AM, (2005) The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. J Biol Chem 280: 32301-32308.
    • (2005) J Biol Chem , vol.280 , pp. 32301-32308
    • Sjoberg, A.1    Onnerfjord, P.2    Morgelin, M.3    Heinegard, D.4    Blom, A.M.5
  • 10
    • 78650070714 scopus 로고    scopus 로고
    • Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis
    • Happonen KE, Saxne T, Aspberg A, Morgelin M, Heinegard D, et al. (2010) Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis. Arthritis Rheum 62: 3574-3583.
    • (2010) Arthritis Rheum , vol.62 , pp. 3574-3583
    • Happonen, K.E.1    Saxne, T.2    Aspberg, A.3    Morgelin, M.4    Heinegard, D.5
  • 11
    • 63149095644 scopus 로고    scopus 로고
    • Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix
    • Happonen KE, Sjoberg AP, Morgelin M, Heinegard D, Blom AM, (2009) Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix. J Immunol 182: 1518-1525.
    • (2009) J Immunol , vol.182 , pp. 1518-1525
    • Happonen, K.E.1    Sjoberg, A.P.2    Morgelin, M.3    Heinegard, D.4    Blom, A.M.5
  • 14
    • 84873030415 scopus 로고    scopus 로고
    • The different roles of aggrecan interaction domains
    • Aspberg A, (2012) The different roles of aggrecan interaction domains. J Histochem Cytochem 60: 987-996.
    • (2012) J Histochem Cytochem , vol.60 , pp. 987-996
    • Aspberg, A.1
  • 15
    • 71449114734 scopus 로고    scopus 로고
    • Proteoglycans and more-from molecules to biology
    • Heinegard D, (2009) Proteoglycans and more-from molecules to biology. Int J Exp Pathol 90: 575-586.
    • (2009) Int J Exp Pathol , vol.90 , pp. 575-586
    • Heinegard, D.1
  • 16
    • 0030963839 scopus 로고    scopus 로고
    • The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety
    • Aspberg A, Miura R, Bourdoulous S, Shimonaka M, Heinegard D, et al. (1997) The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. Proc Natl Acad Sci USA 94: 10116-10121.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10116-10121
    • Aspberg, A.1    Miura, R.2    Bourdoulous, S.3    Shimonaka, M.4    Heinegard, D.5
  • 17
    • 1842425011 scopus 로고    scopus 로고
    • Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins
    • Day JM, Olin AI, Murdoch AD, Canfield A, Sasaki T, et al. (2004) Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins. J Biol Chem 279: 12511-12518.
    • (2004) J Biol Chem , vol.279 , pp. 12511-12518
    • Day, J.M.1    Olin, A.I.2    Murdoch, A.D.3    Canfield, A.4    Sasaki, T.5
  • 18
    • 0033575208 scopus 로고    scopus 로고
    • Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican
    • Aspberg A, Adam S, Kostka G, Timpl R, Heinegard D, (1999) Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican. J Biol Chem 274: 20444-20449.
    • (1999) J Biol Chem , vol.274 , pp. 20444-20449
    • Aspberg, A.1    Adam, S.2    Kostka, G.3    Timpl, R.4    Heinegard, D.5
  • 19
    • 0035847046 scopus 로고    scopus 로고
    • The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding
    • Olin AI, Morgelin M, Sasaki T, Timpl R, Heinegard D, et al. (2001) The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding. J Biol Chem 276: 1253-1261.
    • (2001) J Biol Chem , vol.276 , pp. 1253-1261
    • Olin, A.I.1    Morgelin, M.2    Sasaki, T.3    Timpl, R.4    Heinegard, D.5
  • 20
    • 0037040276 scopus 로고    scopus 로고
    • Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks
    • Isogai Z, Aspberg A, Keene DR, Ono RN, Reinhardt DP, et al. (2002) Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks. J Biol Chem 277: 4565-4572.
    • (2002) J Biol Chem , vol.277 , pp. 4565-4572
    • Isogai, Z.1    Aspberg, A.2    Keene, D.R.3    Ono, R.N.4    Reinhardt, D.P.5
  • 21
    • 0028286068 scopus 로고
    • The chondrodystrophy, nanomelia: biosynthesis and processing of the defective aggrecan precursor
    • Vertel BM, Grier BL, Li H, Schwartz NB, (1994) The chondrodystrophy, nanomelia: biosynthesis and processing of the defective aggrecan precursor. Biochem J 301 (Pt 1): 211-216.
    • (1994) Biochem J , vol.301 , Issue.Pt 1 , pp. 211-216
    • Vertel, B.M.1    Grier, B.L.2    Li, H.3    Schwartz, N.B.4
  • 22
    • 76049108551 scopus 로고    scopus 로고
    • A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans
    • Stattin EL, Wiklund F, Lindblom K, Onnerfjord P, Jonsson BA, et al. (2010) A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans. Am J Hum Genet 86: 126-137.
    • (2010) Am J Hum Genet , vol.86 , pp. 126-137
    • Stattin, E.L.1    Wiklund, F.2    Lindblom, K.3    Onnerfjord, P.4    Jonsson, B.A.5
  • 23
    • 58049198280 scopus 로고    scopus 로고
    • A recessive skeletal dysplasia, SEMD aggrecan type, results from a missense mutation affecting the C-type lectin domain of aggrecan
    • Tompson SW, Merriman B, Funari VA, Fresquet M, Lachman RS, et al. (2009) A recessive skeletal dysplasia, SEMD aggrecan type, results from a missense mutation affecting the C-type lectin domain of aggrecan. Am J Hum Genet 84: 72-79.
    • (2009) Am J Hum Genet , vol.84 , pp. 72-79
    • Tompson, S.W.1    Merriman, B.2    Funari, V.A.3    Fresquet, M.4    Lachman, R.S.5
  • 25
    • 0030069604 scopus 로고    scopus 로고
    • Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage
    • Dudhia J, Davidson CM, Wells TM, Vynios DH, Hardingham TE, et al. (1996) Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage. Biochem J 313 (Pt 3): 933-940.
    • (1996) Biochem J , vol.313 , Issue.Pt 3 , pp. 933-940
    • Dudhia, J.1    Davidson, C.M.2    Wells, T.M.3    Vynios, D.H.4    Hardingham, T.E.5
  • 26
    • 84856100338 scopus 로고    scopus 로고
    • Identification of a central role for complement in osteoarthritis
    • Wang Q, Rozelle AL, Lepus CM, Scanzello CR, Song JJ, et al. (2011) Identification of a central role for complement in osteoarthritis. Nat Med 17: 1674-1679.
    • (2011) Nat Med , vol.17 , pp. 1674-1679
    • Wang, Q.1    Rozelle, A.L.2    Lepus, C.M.3    Scanzello, C.R.4    Song, J.J.5
  • 27
    • 0023085534 scopus 로고
    • Isolation and characterization of proteoglycans
    • Heinegard D, Sommarin Y, (1987) Isolation and characterization of proteoglycans. Methods Enzymol 144: 319-372.
    • (1987) Methods Enzymol , vol.144 , pp. 319-372
    • Heinegard, D.1    Sommarin, Y.2
  • 28
    • 0019472804 scopus 로고
    • Purification and radiolabeling of human C1q
    • Tenner AJ, Lesavre PH, Cooper NR, (1981) Purification and radiolabeling of human C1q. J Immunol 127: 648-653.
    • (1981) J Immunol , vol.127 , pp. 648-653
    • Tenner, A.J.1    Lesavre, P.H.2    Cooper, N.R.3
  • 29
    • 0020530378 scopus 로고
    • Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S
    • Dahlback B, (1983) Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S. Biochem J. 209: 847-856.
    • (1983) Biochem J , vol.209 , pp. 847-856
    • Dahlback, B.1
  • 30
    • 0037210218 scopus 로고    scopus 로고
    • CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b
    • Blom AM, Kask L, Dahlback B, (2003) CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b. Mol Immunol 39: 547-556.
    • (2003) Mol Immunol , vol.39 , pp. 547-556
    • Blom, A.M.1    Kask, L.2    Dahlback, B.3
  • 32
    • 33947593528 scopus 로고    scopus 로고
    • The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levels
    • Munthe-Fog L, Hummelshoj T, Hansen BE, Koch C, Madsen HO, et al. (2007) The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levels. Scand J Immunol 65: 383-392.
    • (2007) Scand J Immunol , vol.65 , pp. 383-392
    • Munthe-Fog, L.1    Hummelshoj, T.2    Hansen, B.E.3    Koch, C.4    Madsen, H.O.5
  • 33
    • 40849126550 scopus 로고    scopus 로고
    • Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state
    • Munthe-Fog L, Hummelshoj T, Ma YJ, Hansen BE, Koch C, et al. (2008) Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state. Mol Immunol 45: 2660-2666.
    • (2008) Mol Immunol , vol.45 , pp. 2660-2666
    • Munthe-Fog, L.1    Hummelshoj, T.2    Ma, Y.J.3    Hansen, B.E.4    Koch, C.5
  • 34
    • 0023587128 scopus 로고
    • Electron microscopy and other physical methods for the characterization of extracellular matrix components: laminin, fibronectin, collagen IV, collagen VI, and proteoglycans
    • Engel J, Furthmayr H, (1987) Electron microscopy and other physical methods for the characterization of extracellular matrix components: laminin, fibronectin, collagen IV, collagen VI, and proteoglycans. Methods Enzymol 145: 3-78.
    • (1987) Methods Enzymol , vol.145 , pp. 3-78
    • Engel, J.1    Furthmayr, H.2
  • 35
    • 4143100146 scopus 로고    scopus 로고
    • Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins
    • Lundell A, Olin AI, Morgelin M, al-Karadaghi S, Aspberg A, et al. (2004) Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins. Structure 12: 1495-1506.
    • (2004) Structure , vol.12 , pp. 1495-1506
    • Lundell, A.1    Olin, A.I.2    Morgelin, M.3    Al-Karadaghi, S.4    Aspberg, A.5
  • 36
    • 77954312934 scopus 로고    scopus 로고
    • Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement
    • Ferreira VP, Cortes C, Pangburn MK, (2010) Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement. Immunobiology 215: 932-940.
    • (2010) Immunobiology , vol.215 , pp. 932-940
    • Ferreira, V.P.1    Cortes, C.2    Pangburn, M.K.3
  • 37
    • 63149095644 scopus 로고    scopus 로고
    • Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix
    • Happonen KE, Sjoberg AP, Morgelin M, Heinegard D, Blom AM, (2009) Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix. J Immunol 182: 1518-1525.
    • (2009) J Immunol , vol.182 , pp. 1518-1525
    • Happonen, K.E.1    Sjoberg, A.P.2    Morgelin, M.3    Heinegard, D.4    Blom, A.M.5
  • 38
    • 0029114993 scopus 로고
    • Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease
    • Wang Y, Rollins SA, Madri JA, Matis LA, (1995) Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease. Proc Natl Acad Sci U S A 92: 8955-8959.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8955-8959
    • Wang, Y.1    Rollins, S.A.2    Madri, J.A.3    Matis, L.A.4
  • 39
    • 38849124271 scopus 로고    scopus 로고
    • A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice
    • Song H, Qiao F, Atkinson C, Holers VM, Tomlinson S, (2007) A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice. J Immunol 179: 7860-7867.
    • (2007) J Immunol , vol.179 , pp. 7860-7867
    • Song, H.1    Qiao, F.2    Atkinson, C.3    Holers, V.M.4    Tomlinson, S.5
  • 40
    • 34249740145 scopus 로고    scopus 로고
    • The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells
    • Sjoberg AP, Trouw LA, Clark SJ, Sjolander J, Heinegard D, et al. (2007) The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. J Biol Chem 282: 10894-10900.
    • (2007) J Biol Chem , vol.282 , pp. 10894-10900
    • Sjoberg, A.P.1    Trouw, L.A.2    Clark, S.J.3    Sjolander, J.4    Heinegard, D.5
  • 41
    • 84859514014 scopus 로고    scopus 로고
    • Islet Amyloid Polypeptide Triggers Limited Complement Activation and Binds Complement Inhibitor C4b-binding Protein, Which Enhances Fibril Formation
    • Sjolander J, Westermark GT, Renstrom E, Blom AM, (2012) Islet Amyloid Polypeptide Triggers Limited Complement Activation and Binds Complement Inhibitor C4b-binding Protein, Which Enhances Fibril Formation. J Biol Chem 287: 10824-10833.
    • (2012) J Biol Chem , vol.287 , pp. 10824-10833
    • Sjolander, J.1    Westermark, G.T.2    Renstrom, E.3    Blom, A.M.4
  • 42
    • 43449086676 scopus 로고    scopus 로고
    • Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly
    • Sjoberg AP, Nystrom S, Hammarstrom P, Blom AM, (2008) Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly. Mol Immunol 45: 3213-3221.
    • (2008) Mol Immunol , vol.45 , pp. 3213-3221
    • Sjoberg, A.P.1    Nystrom, S.2    Hammarstrom, P.3    Blom, A.M.4
  • 43
    • 35348980673 scopus 로고    scopus 로고
    • C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack
    • Trouw LA, Bengtsson AA, Gelderman KA, Dahlback B, Sturfelt G, et al. (2007) C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack. J Biol Chem 282: 28540-28548.
    • (2007) J Biol Chem , vol.282 , pp. 28540-28548
    • Trouw, L.A.1    Bengtsson, A.A.2    Gelderman, K.A.3    Dahlback, B.4    Sturfelt, G.5
  • 44
    • 84866033089 scopus 로고    scopus 로고
    • Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases
    • Happonen KE, Heinegard D, Saxne T, Blom AM, (2012) Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases. Immunobiology 217: 1088-1096.
    • (2012) Immunobiology , vol.217 , pp. 1088-1096
    • Happonen, K.E.1    Heinegard, D.2    Saxne, T.3    Blom, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.