-
2
-
-
81055130123
-
Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration
-
Johnson LV, Forest DL, Banna CD, et al: Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration. Proc Natl Acad Sci USA 108: 18277-18282, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18277-18282
-
-
Johnson, L.V.1
Forest, D.L.2
Banna, C.D.3
-
3
-
-
32444450909
-
Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers
-
Luibl V, Isas JM, Kayed R, Glabe CG, Langen R and Chen J: Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. J Clin Invest 116: 378-385, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 378-385
-
-
Luibl, V.1
Isas, J.M.2
Kayed, R.3
Glabe, C.G.4
Langen, R.5
Chen, J.6
-
4
-
-
0034012166
-
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
-
Mullins RF, Russell SR, Anderson DH and Hageman GS: Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J 14: 835-846, 2000.
-
(2000)
FASEB J
, vol.14
, pp. 835-846
-
-
Mullins, R.F.1
Russell, S.R.2
Anderson, D.H.3
Hageman, G.S.4
-
5
-
-
77949895577
-
Soluble and mature amyloid fibrils in drusen deposits
-
Isas JM, Luibl V, Johnson LV, et al: Soluble and mature amyloid fibrils in drusen deposits. Invest Ophthalmol Vis Sci 51: 1304-1310, 2010.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 1304-1310
-
-
Isas, J.M.1
Luibl, V.2
Johnson, L.V.3
-
6
-
-
65549156409
-
Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/ microglia: Another mechanism of complement activation in age-related macular degeneration
-
Wang J, Ohno-Matsui K, Yoshida T, et al: Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration. J Cell Physiol 220: 119-128, 2009.
-
(2009)
J Cell Physiol
, vol.220
, pp. 119-128
-
-
Wang, J.1
Ohno-Matsui, K.2
Yoshida, T.3
-
7
-
-
47949105602
-
Altered function of factor I caused by amyloid beta: Implication for pathogenesis of age-related macular degeneration from drusen
-
Wang J, Ohno-Matsui K, Yoshida T, et al: Altered function of factor I caused by amyloid beta: Implication for pathogenesis of age-related macular degeneration from drusen. J Immunol 181: 712-720, 2008.
-
(2008)
J Immunol
, vol.181
, pp. 712-720
-
-
Wang, J.1
Ohno-Matsui, K.2
Yoshida, T.3
-
8
-
-
77449129224
-
Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells
-
Kurji KH, Cui JZ, Lin T, et al: Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 51: 1151-1163, 2010.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 1151-1163
-
-
Kurji, K.H.1
Cui, J.Z.2
Lin, T.3
-
9
-
-
0027190763
-
Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments
-
Streilein JW: Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments. Curr Opin Immunol 5: 428-432, 1993.
-
(1993)
Curr Opin Immunol
, vol.5
, pp. 428-432
-
-
Streilein, J.W.1
-
10
-
-
78449234722
-
How to overcome retinal neuropathy: The fight against angiogenesis-related blindness
-
Jo DH, Kim JH and Kim JH: How to overcome retinal neuropathy: The fight against angiogenesis-related blindness. Arch Pharm Res 33: 1557-1565, 2010.
-
(2010)
Arch Pharm Res
, vol.33
, pp. 1557-1565
-
-
Jo, D.H.1
Kim, J.H.2
Kim, J.H.3
-
12
-
-
0942287243
-
Oxidative stress affects the junctional integrity of retinal pigment epithelial cells
-
Bailey TA, Kanuga N, Romero IA, Greenwood J, Luthert PJ and Cheetham ME: Oxidative stress affects the junctional integrity of retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 45: 675-684, 2004.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 675-684
-
-
Bailey, T.A.1
Kanuga, N.2
Romero, I.A.3
Greenwood, J.4
Luthert, P.J.5
Cheetham, M.E.6
-
13
-
-
84867383694
-
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium
-
Peng S, Gan G, Rao VS, Adelman RA and Rizzolo LJ: Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium. Invest Ophthalmol Vis Sci 53: 5016-5028, 2012.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 5016-5028
-
-
Peng, S.1
Gan, G.2
Rao, V.S.3
Adelman, R.A.4
Rizzolo, L.J.5
-
14
-
-
84863230646
-
Matrix Metalloproteinase2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage
-
Liu J, Jin X, Liu KJ and Liu W: Matrix metalloproteinase2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage. J Neurosci 32: 3044-3057, 2012.
-
(2012)
J Neurosci
, vol.32
, pp. 3044-3057
-
-
Liu, J.1
Jin, X.2
Liu, K.J.3
Liu, W.4
-
15
-
-
80052037570
-
Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: Role of tight junction proteins and matrix metalloproteinase-9
-
Martins T, Baptista S, Gonçalves J, et al: Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: Role of tight junction proteins and matrix metalloproteinase-9. Brain Res 1411: 28-40, 2011.
-
(2011)
Brain Res
, vol.1411
, pp. 28-40
-
-
Martins, T.1
Baptista, S.2
Gonçalves, J.3
-
16
-
-
63549133336
-
Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells
-
Bruban J, Glotin AL, Dinet V, et al: Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells. Aging Cell 8: 162-177, 2009.
-
(2009)
Aging Cell
, vol.8
, pp. 162-177
-
-
Bruban, J.1
Glotin, A.L.2
Dinet, V.3
-
17
-
-
33748100271
-
Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue
-
Maminishkis A, Chen S, Jalickee S, et al: Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue. Invest Ophthalmol Vis Sci 47: 3612-3624, 2006.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 3612-3624
-
-
Maminishkis, A.1
Chen, S.2
Jalickee, S.3
-
18
-
-
80052400212
-
Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium
-
Suzuki T, Yoshinaga N and Tanabe S: Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium. J Biol Chem 286: 31263-31271, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 31263-31271
-
-
Suzuki, T.1
Yoshinaga, N.2
Tanabe, S.3
-
19
-
-
80051709700
-
Matrix metalloproteinase-2 and-9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins
-
Feng S, Cen J, Huang Y, et al: Matrix metalloproteinase-2 and-9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins. PLoS One 6: E20599, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Feng, S.1
Cen, J.2
Huang, Y.3
-
20
-
-
77950516409
-
Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement
-
Bauer AT, Bürgers HF, Rabie T and Marti HH: Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement. J Cereb Blood Flow Metab 30: 837-848, 2010.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 837-848
-
-
Bauer, A.T.1
Bürgers, H.F.2
Rabie, T.3
Marti, H.H.4
-
21
-
-
36849094431
-
Matrix metalloproteinases as modulators of inflammation
-
Manicone AM and McGuire JK: Matrix metalloproteinases as modulators of inflammation. Semin Cell Dev Biol 19: 34-41, 2008.
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 34-41
-
-
Manicone, A.M.1
McGuire, J.K.2
-
22
-
-
84864404796
-
Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration
-
Jonas JB, Tao Y, Neumaier M and Findeisen P: Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration. Acta Ophthalmol 90: E381-e388, 2012.
-
(2012)
Acta Ophthalmol
, vol.90
-
-
Jonas, J.B.1
Tao, Y.2
Neumaier, M.3
Findeisen, P.4
-
23
-
-
84863309299
-
Sequential in-office vitreous aspirates demonstrate vitreous matrix metalloproteinase 9 levels correlate with the amount of subretinal fluid in eyes with wet age-related macular degeneration
-
Ecker SM, Pfahler SM, Hines JC, Lovelace AS and Glaser BM: Sequential in-office vitreous aspirates demonstrate vitreous matrix metalloproteinase 9 levels correlate with the amount of subretinal fluid in eyes with wet age-related macular degeneration. Mol Vis 18: 1658-1667, 2012.
-
(2012)
Mol Vis
, vol.18
, pp. 1658-1667
-
-
Ecker, S.M.1
Pfahler, S.M.2
Hines, J.C.3
Lovelace, A.S.4
Glaser, B.M.5
-
24
-
-
84860257682
-
Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation
-
Jeong S, Ledee DR, Gordon GM, et al: Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation. Am J Pathol 180: 2028-2039, 2012.
-
(2012)
Am J Pathol
, vol.180
, pp. 2028-2039
-
-
Jeong, S.1
Ledee, D.R.2
Gordon, G.M.3
-
25
-
-
80052827055
-
EMMPRIN modulates epithelial barrier function through a MMP-mediated occludin cleavage: Implications in dry eye disease
-
Huet E, Vallée B, Delbé J, et al: EMMPRIN modulates epithelial barrier function through a MMP-mediated occludin cleavage: Implications in dry eye disease. Am J Pathol 179: 1278-1286, 2011.
-
(2011)
Am J Pathol
, vol.179
, pp. 1278-1286
-
-
Huet, E.1
Vallée, B.2
Delbé, J.3
-
26
-
-
11144221616
-
Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye
-
Pflugfelder SC, Farley W, Luo L, et al: Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye. Am J Pathol 166: 61-71, 2005.
-
(2005)
Am J Pathol
, vol.166
, pp. 61-71
-
-
Pflugfelder, S.C.1
Farley, W.2
Luo, L.3
-
27
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R, Head E, Thompson JL, et al: Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300: 486-489, 2003.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
-
28
-
-
18744362465
-
Matrix metalloproteinases in early diabetic retinopathy and their role in alteration of the blood-retinal barrier
-
Giebel SJ, Menicucci G, McGuire PG and Das A: Matrix metalloproteinases in early diabetic retinopathy and their role in alteration of the blood-retinal barrier. Lab Invest 85: 597-607, 2005.
-
(2005)
Lab Invest
, vol.85
, pp. 597-607
-
-
Giebel, S.J.1
Menicucci, G.2
McGuire, P.G.3
Das, A.4
-
29
-
-
45449091963
-
Plasma levels of matrix metalloproteinase-2 and-9 (MMP-2 and MMP-9) in age-related macular degeneration
-
Chau KY, Sivaprasad S, Patel N, Donaldson TA, Luthert PJ and Chong NV: Plasma levels of matrix metalloproteinase-2 and-9 (MMP-2 and MMP-9) in age-related macular degeneration. Eye 22: 855-859, 2008.
-
(2008)
Eye
, vol.22
, pp. 855-859
-
-
Chau, K.Y.1
Sivaprasad, S.2
Patel, N.3
Donaldson, T.A.4
Luthert, P.J.5
Chong, N.V.6
-
30
-
-
77952147434
-
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration
-
Chen W, Stambolian D, Edwards AO, et al: Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci USA 107: 7401-7406, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7401-7406
-
-
Chen, W.1
Stambolian, D.2
Edwards, A.O.3
-
31
-
-
0025911428
-
Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin
-
Balda MS, Gonzalez-Mariscal L, Contreras RG, et al: Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin. J Membr Biol 122: 193-202, 1991.
-
(1991)
J Membr Biol
, vol.122
, pp. 193-202
-
-
Balda, M.S.1
Gonzalez-Mariscal, L.2
Contreras, R.G.3
-
32
-
-
84863572607
-
Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement
-
Bandyopadhyay M and Rohrer B: Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement. Invest Ophthalmol Vis Sci 53: 1953-1961, 2012.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 1953-1961
-
-
Bandyopadhyay, M.1
Rohrer, B.2
-
33
-
-
84862885703
-
Aβ1-42-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca?+-calcineurin signaling
-
Kook SY, Hong HS, Moon M, Ha CM, Chang S and Mook-Jung I: Aβ1-42-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca?+-calcineurin signaling. J Neurosci 32: 8845-8854, 2012.
-
(2012)
J Neurosci
, vol.32
, pp. 8845-8854
-
-
Kook, S.Y.1
Hong, H.S.2
Moon, M.3
Ha, C.M.4
Chang, S.5
Mook-Jung, I.6
-
34
-
-
33947493213
-
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store
-
Thibault O, Gant JC and Landfield PW: Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: Minding the store. Aging Cell 6: 307-317, 2007.
-
(2007)
Aging Cell
, vol.6
, pp. 307-317
-
-
Thibault, O.1
Gant, J.C.2
Landfield, P.W.3
-
35
-
-
84869094484
-
Aβ leads to Ca2+ signaling alterations and transcriptional changes in glial cells
-
Grolla AA, Fakhfouri G, Balzaretti G, et al: Aβ leads to Ca2+ signaling alterations and transcriptional changes in glial cells. Neurobiol Aging 34: 511-522, 2013.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 511-522
-
-
Grolla, A.A.1
Fakhfouri, G.2
Balzaretti, G.3
-
36
-
-
61349096009
-
Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
-
Kuchibhotla KV, Lattarulo CR, Hyman BT and Bacskai BJ: Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323: 1211-1215, 2009.
-
(2009)
Science
, vol.323
, pp. 1211-1215
-
-
Kuchibhotla, K.V.1
Lattarulo, C.R.2
Hyman, B.T.3
Bacskai, B.J.4
-
37
-
-
0034512703
-
Differential regulation of the secretions of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases-1 from human keratinocytes in culture
-
Kobayashi T, Hattori S, Nagai Y and Tajima S: Differential regulation of the secretions of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases-1 from human keratinocytes in culture. IUBMB Life 50: 221-226, 2000.
-
(2000)
IUBMB Life
, vol.50
, pp. 221-226
-
-
Kobayashi, T.1
Hattori, S.2
Nagai, Y.3
Tajima, S.4
|