-
2
-
-
3042833166
-
The NR2B-selective NMDA receptor antagonist CP-101,606 exacerbates L-DOPA-induced dyskinesia and provides mild potentiation of anti-parkinsonian effects of L-DOPA in the MPTP-lesioned marmoset model of Parkinson's disease
-
Nash JE, Ravenscroft P, McGuire S, Crossman AR, Menniti FS, Brotchie JM. The NR2B-selective NMDA receptor antagonist CP-101, 606 exacerbates L-DOPA-induced dyskinesia and provides mild potentiation of anti-parkinsonian effects of L-DOPA in the MPTP-lesioned marmoset model of Parkinson's disease. Exp Neurol. 2004;188:471-479.
-
(2004)
Exp Neurol.
, vol.188
, pp. 471-479
-
-
Nash, J.E.1
Ravenscroft, P.2
McGuire, S.3
Crossman, A.R.4
Menniti, F.S.5
Brotchie, J.M.6
-
3
-
-
14744290753
-
Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease
-
Hallett PJ, Dunah, AW, Ravenscroft P, et al. Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. Neuropharmacology. 2005;48:503-516.
-
(2005)
Neuropharmacology.
, vol.48
, pp. 503-516
-
-
Hallett, P.J.1
Dunah, A.W.2
Ravenscroft, P.3
-
4
-
-
84863439199
-
Targeting NR2A-containing NMDA receptors reduces L-DOPA-induced dyskinesias
-
Gardoni F, Sgobio C, Pendolino V, Calabresi P, Di Luca M, Picconi B. Targeting NR2A-containing NMDA receptors reduces L-DOPA-induced dyskinesias. Neurobiol Aging. 2012;33:2138-2144
-
(2012)
Neurobiol Aging.
, vol.33
, pp. 2138-2144
-
-
Gardoni, F.1
Sgobio, C.2
Pendolino, V.3
Calabresi, P.4
Di Luca, M.5
Picconi, B.6
-
5
-
-
0028169661
-
Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition
-
Laurie DJ, Seeburg PH. Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition. Eur J Pharmacol. 1994;268:335-345.
-
(1994)
Eur J Pharmacol.
, vol.268
, pp. 335-345
-
-
Laurie, D.J.1
Seeburg, P.H.2
-
6
-
-
0027469106
-
The glycine site of the NMDA receptor-five years on
-
Kemp JA, Leeson PD. The glycine site of the NMDA receptor-five years on. Trends Pharmacol Sci. 1993;14:20-25.
-
(1993)
Trends Pharmacol Sci.
, vol.14
, pp. 20-25
-
-
Kemp, J.A.1
Leeson, P.D.2
-
7
-
-
0023915822
-
Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity
-
Cotman CW, Monaghan DT, Ganong AH. Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity. Annu Rev Neurosci. 1988;11:61-80.
-
(1988)
Annu Rev Neurosci.
, vol.11
, pp. 61-80
-
-
Cotman, C.W.1
Monaghan, D.T.2
Ganong, A.H.3
-
8
-
-
0034332480
-
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
-
Awad H, Hubert GW, Smith Y, Levey AI, Conn PJ. Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci. 2000;20:7871-7879.
-
(2000)
J Neurosci.
, vol.20
, pp. 7871-7879
-
-
Awad, H.1
Hubert, G.W.2
Smith, Y.3
Levey, A.I.4
Conn, P.J.5
-
9
-
-
0037273830
-
Glutamate receptors and Parkinson's disease: opportunities for intervention
-
Marino MJ, Valenti O, Conn PJ. Glutamate receptors and Parkinson's disease: opportunities for intervention. Drugs Aging. 2003;20:377-397.
-
(2003)
Drugs Aging.
, vol.20
, pp. 377-397
-
-
Marino, M.J.1
Valenti, O.2
Conn, P.J.3
-
10
-
-
13544268511
-
N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease
-
Waxman EA, Lynch DR. N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease. Neuroscientist. 2005;11:37-49.
-
(2005)
Neuroscientist.
, vol.11
, pp. 37-49
-
-
Waxman, E.A.1
Lynch, D.R.2
-
11
-
-
0032797570
-
Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys
-
Blanchet PJ, Konitsiotis S, Whittemore ER, Zhou ZL, Woodward RM, Chase TN. Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys. J Pharmacol Exp Ther. 1999;290:1034-1040.
-
(1999)
J Pharmacol Exp Ther.
, vol.290
, pp. 1034-1040
-
-
Blanchet, P.J.1
Konitsiotis, S.2
Whittemore, E.R.3
Zhou, Z.L.4
Woodward, R.M.5
Chase, T.N.6
-
12
-
-
54249111876
-
Neuroprotective effects of a selective N-methyl-D-aspartate NR2B receptor antagonist in the 6-hydroxydopamine rat model of Parkinson's disease
-
Leaver KR, Allbutt HN, Creber NJ, Kassiou M, Henderson JM. Neuroprotective effects of a selective N-methyl-D-aspartate NR2B receptor antagonist in the 6-hydroxydopamine rat model of Parkinson's disease. Clin Exp Pharmacol Physiol. 2008;35:1388-1394
-
(2008)
Clin Exp Pharmacol Physiol.
, vol.35
, pp. 1388-1394
-
-
Leaver, K.R.1
Allbutt, H.N.2
Creber, N.J.3
Kassiou, M.4
Henderson, J.M.5
-
14
-
-
0031985972
-
Direct and indirect presynaptic control of dopamine release by excitatory amino acids
-
Chéremy A, L'hirondel M, Godeheu G, et al. Direct and indirect presynaptic control of dopamine release by excitatory amino acids. Amino Acids. 1998;14:63-68.
-
(1998)
Amino Acids.
, vol.14
, pp. 63-68
-
-
Chéremy, A.1
L'hirondel, M.2
Godeheu, G.3
-
15
-
-
0031975703
-
Role of excitatory amino acids in the regulation of dopamine synthesis and release in the neostriatum
-
Zigmond MJ, Castro SL, Keefe KA, Abercrombie ED, Sved AF. Role of excitatory amino acids in the regulation of dopamine synthesis and release in the neostriatum. Amino Acids. 1998;4:57-62.
-
(1998)
Amino Acids.
, vol.4
, pp. 57-62
-
-
Zigmond, M.J.1
Castro, S.L.2
Keefe, K.A.3
Abercrombie, E.D.4
Sved, A.F.5
-
16
-
-
1642338752
-
Glycine and D-cycloserine attenuate vacuous chewing movements in a rat model of tardive dyskinesia
-
Shoham S, Mazeh M, Javitt DC, Heresco-Levy U. Glycine and D-cycloserine attenuate vacuous chewing movements in a rat model of tardive dyskinesia. Brain Res. 2004;1004:142-147.
-
(2004)
Brain Res.
, vol.1004
, pp. 142-147
-
-
Shoham, S.1
Mazeh, M.2
Javitt, D.C.3
Heresco-Levy, U.4
-
17
-
-
79952704032
-
Effects of D-cycloserine on MPTP-induced behavioral and neurological changes; potential for treatment of Parkinson's disease dementia
-
Ho Y, Mo S, Pawlak CR, Yeh K. Effects of D-cycloserine on MPTP-induced behavioral and neurological changes; potential for treatment of Parkinson's disease dementia. Behav Brain Res. 2011;219:280-290.
-
(2011)
Behav Brain Res.
, vol.219
, pp. 280-290
-
-
Ho, Y.1
Mo, S.2
Pawlak, C.R.3
Yeh, K.4
-
18
-
-
0034737761
-
Effects of the partial glycine agonist D-cycloserine on cognitive functioning in chronic low-dose MPTP-treated monkeys
-
Schneider GS, Tinker JP, Van Velson M, Giardiniere M. Effects of the partial glycine agonist D-cycloserine on cognitive functioning in chronic low-dose MPTP-treated monkeys. Brain Res. 2000;860:190-194.
-
(2000)
Brain Res.
, vol.860
, pp. 190-194
-
-
Schneider, G.S.1
Tinker, J.P.2
Van Velson, M.3
Giardiniere, M.4
-
19
-
-
0036139613
-
Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment
-
Calon F, Morissette M, Ghribi O, et al. Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-treated monkeys following dopamine agonist treatment. Prog Neuropsychopharmacol Biol Psychiatry. 2002;26:127-138.
-
(2002)
Prog Neuropsychopharmacol Biol Psychiatry.
, vol.26
, pp. 127-138
-
-
Calon, F.1
Morissette, M.2
Ghribi, O.3
-
20
-
-
0035873734
-
Chronic high-dose glycine nutrition: effects on rat brain cell morphology
-
Shoham S, Javitt DC, Heresco-Levy U. Chronic high-dose glycine nutrition: effects on rat brain cell morphology. Biol Psychiatry. 2001;49:876-885.
-
(2001)
Biol Psychiatry.
, vol.49
, pp. 876-885
-
-
Shoham, S.1
Javitt, D.C.2
Heresco-Levy, U.3
-
21
-
-
0345300589
-
Amino acid transmitter systems in schizophrenia and other psychotic disorders
-
In: D'haenen H, den Boer JA, Westenberg M, Willner P, eds. London: John Wiley & Sons.
-
Heresco-Levy U. Amino acid transmitter systems in schizophrenia and other psychotic disorders. In: D'haenen H, den Boer JA, Westenberg M, Willner P, eds. Biological Psychiatry. London: John Wiley & Sons; 2002:587-600.
-
(2002)
Biological Psychiatry
, pp. 587-600
-
-
Heresco-Levy, U.1
-
22
-
-
8744278883
-
Glutamate as a therapeutic target in psychiatric disorders
-
Javitt DC. Glutamate as a therapeutic target in psychiatric disorders. Mol Psychiatry. 2004: 9:1-4.
-
(2004)
Mol Psychiatry.
, vol.9
, pp. 1-4
-
-
Javitt, D.C.1
-
23
-
-
78649995149
-
Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis
-
Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon, R Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol. 2011;10:63-64.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 63-64
-
-
Dalmau, J.1
Lancaster, E.2
Martinez-Hernandez, E.3
Rosenfeld, M.R.4
Balice-Gordon, R.5
-
24
-
-
77949447469
-
Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia: a critical review and data-analysis
-
Tsai GE, Lin P. Strategies to enhance N-methyl-D-aspartate receptor-mediated neurotransmission in schizophrenia: a critical review and data-analysis. Curr Pharm Design. 2010;16:522-537.
-
(2010)
Curr Pharm Design.
, vol.16
, pp. 522-537
-
-
Tsai, G.E.1
Lin, P.2
-
25
-
-
15444377601
-
D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia
-
Heresco-Levy U, Javitt DC, Ebstein R, et al. D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia. Biol Psychiatry. 2005;57:577-585.
-
(2005)
Biol Psychiatry.
, vol.57
, pp. 577-585
-
-
Heresco-Levy, U.1
Javitt, D.C.2
Ebstein, R.3
-
26
-
-
1442333154
-
High dose glycine added to olanzapine and risperidone for the treatment of schizophrenia
-
Heresco-Levy U, Javitt DC, Ermilov M, Lichtenberg P, Bar G. High dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Biol Psychiatry. 2004;2:165-171.
-
(2004)
Biol Psychiatry.
, vol.2
, pp. 165-171
-
-
Heresco-Levy, U.1
Javitt, D.C.2
Ermilov, M.3
Lichtenberg, P.4
Bar, G.5
-
28
-
-
0032925438
-
Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia
-
Heresco-Levy U, Javitt DC, Ermilov M, Mordel C, Silipo G, Lichtenstein M. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry. 1999;56:29-36.
-
(1999)
Arch Gen Psychiatry.
, vol.56
, pp. 29-36
-
-
Heresco-Levy, U.1
Javitt, D.C.2
Ermilov, M.3
Mordel, C.4
Silipo, G.5
Lichtenstein, M.6
-
29
-
-
0014723449
-
A rating scale for extrapyramidal side effects
-
Simpson GM, Angus JWS. A rating scale for extrapyramidal side effects. Acta Psych Scand. 1970;212(Suppl):11-19.
-
(1970)
Acta Psych Scand.
, vol.212
, Issue.SUPPL
, pp. 11-19
-
-
Simpson, G.M.1
Angus, J.W.S.2
-
30
-
-
0003412410
-
-
Rockville, MD: US Department of Health, Education and Welfare Publication (ADM).
-
Guy W. ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: US Department of Health, Education and Welfare Publication (ADM); 1976:76-338.
-
(1976)
ECDEU Assessment Manual for Psychopharmacology
, pp. 76-338
-
-
Guy, W.1
-
31
-
-
57049117070
-
Apathy and anhedonia rating scales in Parkinson's disease: critique and recommendations
-
Leentjens, AFG, Dujardin K, Marsh L, et al. Apathy and anhedonia rating scales in Parkinson's disease: critique and recommendations. Mov Disord. 2008;23:2004-2014.
-
(2008)
Mov Disord.
, vol.23
, pp. 2004-2014
-
-
Leentjens, A.F.G.1
Dujardin, K.2
Marsh, L.3
-
32
-
-
80054121879
-
Apathy and depression scales in Parkinson's disease. Are they good enough?
-
Schrag A. Apathy and depression scales in Parkinson's disease. Are they good enough? J Neurol Sci. 2011;310:216-219.
-
(2011)
J Neurol Sci.
, vol.310
, pp. 216-219
-
-
Schrag, A.1
-
33
-
-
84855555111
-
Neurocognitive correlates of apathy and anxiety in Parkinson's disease
-
Bogdanova Y, Cronin-Golomb A. Neurocognitive correlates of apathy and anxiety in Parkinson's disease. Parkinsons Dis. 2012;2012:793076.
-
(2012)
Parkinsons Dis.
, vol.2012
, pp. 793076
-
-
Bogdanova, Y.1
Cronin-Golomb, A.2
-
34
-
-
84862680877
-
D-serine adjuvant treatment alleviates behavioural and motor symptoms in Parkinson's disease
-
Gelfin E, Kaufman Y, Korn-Lubetsky I, et al. D-serine adjuvant treatment alleviates behavioural and motor symptoms in Parkinson's disease. Int J Neuropsychopharmacol. 2012;15:543-549.
-
(2012)
Int J Neuropsychopharmacol.
, vol.15
, pp. 543-549
-
-
Gelfin, E.1
Kaufman, Y.2
Korn-Lubetsky, I.3
-
36
-
-
0026526276
-
Long-term synaptic depression in the striatum: physiological and pharmacological characterization
-
Calabresi P, Maj R, Pisani A, Mercuri NB, Bernardi G. Long-term synaptic depression in the striatum: physiological and pharmacological characterization. J Neurosci. 1992;12:4224-4233.
-
(1992)
J Neurosci.
, vol.12
, pp. 4224-4233
-
-
Calabresi, P.1
Maj, R.2
Pisani, A.3
Mercuri, N.B.4
Bernardi, G.5
-
37
-
-
0033398532
-
Unilateral dopamine denervation blocks corticostriatal LTP
-
Centonze D., Gubellini P, Picconi B, Calabresi P, Giacomini P, Bernardi GJ. Unilateral dopamine denervation blocks corticostriatal LTP. J Neurophysiol. 1999;82:3575-3579.
-
(1999)
J Neurophysiol.
, vol.82
, pp. 3575-3579
-
-
Centonze, D.1
Gubellini, P.2
Picconi, B.3
Calabresi, P.4
Giacomini, P.5
Bernardi, G.J.6
-
38
-
-
77958523402
-
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition
-
Paillé V, Picconi B, Bagetta V, et al. Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition. J Neurosci. 2010;30:14182-14193.
-
(2010)
J Neurosci.
, vol.30
, pp. 14182-14193
-
-
Paillé, V.1
Picconi, B.2
Bagetta, V.3
-
39
-
-
2942586826
-
Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism
-
Picconi B, Gardoni F, Centonze D, et al. Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism. J Neurosci. 2004;24:5283-5291.
-
(2004)
J Neurosci.
, vol.24
, pp. 5283-5291
-
-
Picconi, B.1
Gardoni, F.2
Centonze, D.3
-
40
-
-
33644995350
-
A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesia
-
Gardoni F, Picconi B, Ghiglieri V, et al. A critical interaction between NR2B and MAGUK in L-DOPA induced dyskinesia. J Neurosci. 2006;26:2914-2922.
-
(2006)
J Neurosci.
, vol.26
, pp. 2914-2922
-
-
Gardoni, F.1
Picconi, B.2
Ghiglieri, V.3
-
41
-
-
0036589832
-
Characterisation of striatal NMDARs involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat
-
Nash JE, Brotchie JM. Characterisation of striatal NMDARs involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat. Mov Disord. 2002;17:455-466.
-
(2002)
Mov Disord.
, vol.17
, pp. 455-466
-
-
Nash, J.E.1
Brotchie, J.M.2
-
42
-
-
0036250086
-
NR2B selective NMDA receptor antagonists
-
Nikam SS, Meltzer LT. NR2B selective NMDA receptor antagonists. Curr Pharm Des. 2002;8:845-855.
-
(2002)
Curr Pharm Des.
, vol.8
, pp. 845-855
-
-
Nikam, S.S.1
Meltzer, L.T.2
-
43
-
-
36649008903
-
Hippocampal long-term synaptic plasticity and signal amplification of NMDA receptors
-
MacDonald JF, Jackson MF, Beazely MA. Hippocampal long-term synaptic plasticity and signal amplification of NMDA receptors. Crit Rev Neurobiol. 2006;18:71-84.
-
(2006)
Crit Rev Neurobiol.
, vol.18
, pp. 71-84
-
-
MacDonald, J.F.1
Jackson, M.F.2
Beazely, M.A.3
-
44
-
-
67349155567
-
NR2A-containing NMDA receptors are required for LTP induction in rat dorsolateral striatum in vitro
-
Li P, Li YH, Han TZ. NR2A-containing NMDA receptors are required for LTP induction in rat dorsolateral striatum in vitro. Brain Res. 2009;1274:40-46.
-
(2009)
Brain Res.
, vol.1274
, pp. 40-46
-
-
Li, P.1
Li, Y.H.2
Han, T.Z.3
-
45
-
-
66149118691
-
Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane
-
Balan L, Foltyn VN, Zehl M, et al. Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane. Proc Natl Acad Sci USA. 2009;106:7589-7594.
-
(2009)
Proc Natl Acad Sci USA.
, vol.106
, pp. 7589-7594
-
-
Balan, L.1
Foltyn, V.N.2
Zehl, M.3
-
46
-
-
33847253971
-
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation
-
Mustafa AK, Kumar M, Selvakumar B, et al. Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proc Natl Acad Sci U S A. 2007;104:2950-2955.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, pp. 2950-2955
-
-
Mustafa, A.K.1
Kumar, M.2
Selvakumar, B.3
-
47
-
-
78650856866
-
D-amino acid oxidase knockdown in the mouse cerebellum reduces NR2A mRNA
-
Burnet PW, Anderson PN, Chen L, Nikiforova N, Harrison PJ, Wood MJ. D-amino acid oxidase knockdown in the mouse cerebellum reduces NR2A mRNA. Mol Cell Neurosci. 2011;46:167-175.
-
(2011)
Mol Cell Neurosci.
, vol.46
, pp. 167-175
-
-
Burnet, P.W.1
Anderson, P.N.2
Chen, L.3
Nikiforova, N.4
Harrison, P.J.5
Wood, M.J.6
|