-
1
-
-
84861160503
-
The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells
-
Biarc J, Chalkley RJ, Burlingame AL, Bradshaw RA. The induction of serine/threonine protein phosphorylations by a PDGFR/TrkA chimera in stably transfected PC12 cells. Mol Cell Proteomics. 2012; 11: 15-30.
-
(2012)
Mol Cell Proteomics
, vol.11
, pp. 15-30
-
-
Biarc, J.1
Chalkley, R.J.2
Burlingame, A.L.3
Bradshaw, R.A.4
-
2
-
-
79961141696
-
Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival
-
Harrington AW, St Hillaire C, Zweifel LS, Glebova NO, Philippidou P, Halegoua S, et al. Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival. Cell. 2011; 146: 421-434.
-
(2011)
Cell
, vol.146
, pp. 421-434
-
-
Harrington, A.W.1
St Hillaire, C.2
Zweifel, L.S.3
Glebova, N.O.4
Philippidou, P.5
Halegoua, S.6
-
3
-
-
84867034578
-
The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition
-
Bertrand T, Kothe M, Liu J, Dupuy A, Rak A, Berne PF, et al. The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition. J Mol Biol. 2012; 423: 439-453.
-
(2012)
J Mol Biol
, vol.423
, pp. 439-453
-
-
Bertrand, T.1
Kothe, M.2
Liu, J.3
Dupuy, A.4
Rak, A.5
Berne, P.F.6
-
4
-
-
80052598258
-
Expression of nerve growth factor and its receptors, TrkA and p75, in porcine ovaries
-
Jana B, Koszykowska M, Czarzasta J. Expression of nerve growth factor and its receptors, TrkA and p75, in porcine ovaries. J Reprod Dev. 2011; 57: 468-474.
-
(2011)
J Reprod Dev
, vol.57
, pp. 468-474
-
-
Jana, B.1
Koszykowska, M.2
Czarzasta, J.3
-
5
-
-
75149161734
-
Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells
-
Li C, Macdonald JI, Hryciw T, Meakin SO. Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells. J Neurochem. 2010; 112: 882-899.
-
(2010)
J Neurochem
, vol.112
, pp. 882-899
-
-
Li, C.1
Macdonald, J.I.2
Hryciw, T.3
Meakin, S.O.4
-
6
-
-
77956300096
-
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not
-
Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, et al. Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not. Nature. 2010; 467: 59-63.
-
(2010)
Nature
, vol.467
, pp. 59-63
-
-
Nikoletopoulou, V.1
Lickert, H.2
Frade, J.M.3
Rencurel, C.4
Giallonardo, P.5
Zhang, L.6
-
7
-
-
0032927906
-
Neuroblastoma as a neurobiological disease
-
Schor NF. Neuroblastoma as a neurobiological disease. J Neurooncol. 1999; 41: 159-616.
-
(1999)
J Neurooncol
, vol.41
, pp. 159-616
-
-
Schor, N.F.1
-
8
-
-
33751020831
-
p53 is required for nerve growth factor-mediated differentiation of PC12 cells via regulation of TrkA levels
-
Zhang J, Yan W, Chen X. p53 is required for nerve growth factor-mediated differentiation of PC12 cells via regulation of TrkA levels. Cell Death Differ. 2006; 13: 2118-2128.
-
(2006)
Cell Death Differ
, vol.13
, pp. 2118-2128
-
-
Zhang, J.1
Yan, W.2
Chen, X.3
-
9
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 1995; 270: 1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
11
-
-
0345832090
-
Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor
-
Horowitz JC, Lee DY, Waghray M, Keshamouni VG, Thomas PE, Zhang H, et al. Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor. J Biol Chem. 2004; 279: 1359-1367.
-
(2004)
J Biol Chem
, vol.279
, pp. 1359-1367
-
-
Horowitz, J.C.1
Lee, D.Y.2
Waghray, M.3
Keshamouni, V.G.4
Thomas, P.E.5
Zhang, H.6
-
12
-
-
44449108011
-
MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: Opposite roles of p38alpha and p38delta
-
Zhou X, Ferraris JD, Dmitrieva NI, Liu Y, Burg MB. MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta. Proc Natl Acad Sci U S A. 2008; 105: 5620-5625.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5620-5625
-
-
Zhou, X.1
Ferraris, J.D.2
Dmitrieva, N.I.3
Liu, Y.4
Burg, M.B.5
-
13
-
-
0033485261
-
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
-
Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E, et al. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J. 1999; 18: 6845-6854.
-
(1999)
EMBO J
, vol.18
, pp. 6845-6854
-
-
Bulavin, D.V.1
Saito, S.2
Hollander, M.C.3
Sakaguchi, K.4
Anderson, C.W.5
Appella, E.6
-
14
-
-
17844398046
-
Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase
-
Gutierrez MC, Detre S, Johnston S, Mohsin SK, Shou J, Allred DC, et al. Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase. J Clin Oncol. 2005; 23: 2469-2476.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2469-2476
-
-
Gutierrez, M.C.1
Detre, S.2
Johnston, S.3
Mohsin, S.K.4
Shou, J.5
Allred, D.C.6
-
15
-
-
1442274808
-
p38 MAP kinase: A convergence point in cancer therapy
-
Olson JM, Hallahan AR. p38 MAP kinase: a convergence point in cancer therapy. Trends Mol Med. 2004; 10: 125-129.
-
(2004)
Trends Mol Med
, vol.10
, pp. 125-129
-
-
Olson, J.M.1
Hallahan, A.R.2
-
17
-
-
33847219580
-
A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity
-
Yu W, Imoto I, Inoue J, Onda M, Emi M, Inazawa J. A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity. Oncogene. 2007; 26: 1178-1187.
-
(2007)
Oncogene
, vol.26
, pp. 1178-1187
-
-
Yu, W.1
Imoto, I.2
Inoue, J.3
Onda, M.4
Emi, M.5
Inazawa, J.6
-
18
-
-
38449108441
-
siRNA directed against TrkA sensitizes human pancreatic cancer cells to apoptosis induced by gemcitabine through an inactivation of PI3K/Akt-dependent pathway
-
Liu D, Zhang Y, Dang C, Ma Q, Lee W, Chen W. siRNA directed against TrkA sensitizes human pancreatic cancer cells to apoptosis induced by gemcitabine through an inactivation of PI3K/Akt-dependent pathway. Oncol Rep. 2007; 18: 673-677.
-
(2007)
Oncol Rep
, vol.18
, pp. 673-677
-
-
Liu, D.1
Zhang, Y.2
Dang, C.3
Ma, Q.4
Lee, W.5
Chen, W.6
-
19
-
-
34250378582
-
Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro
-
Festuccia C, Muzi P, Gravina GL, Millimaggi D, Speca S, Dolo V, et al. Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro. Int J Oncol. 2007; 30: 193-200.
-
(2007)
Int J Oncol
, vol.30
, pp. 193-200
-
-
Festuccia, C.1
Muzi, P.2
Gravina, G.L.3
Millimaggi, D.4
Speca, S.5
Dolo, V.6
-
20
-
-
0033584858
-
Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor
-
Baricordi OR, Melchiorri L, Adinolfi E, Falzoni S, Chiozzi P, Buell G, et al. Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor. J Biol Chem. 1999; 274: 33206-33208.
-
(1999)
J Biol Chem
, vol.274
, pp. 33206-33208
-
-
Baricordi, O.R.1
Melchiorri, L.2
Adinolfi, E.3
Falzoni, S.4
Chiozzi, P.5
Buell, G.6
-
21
-
-
77953699065
-
ATP stimulates the proliferation of MCF-7 cells through the PI3K/Akt signaling pathway
-
Bilbao PS, Santillan G, Boland R. ATP stimulates the proliferation of MCF-7 cells through the PI3K/Akt signaling pathway. Arch Biochem Biophys. 2010; 499: 40-48.
-
(2010)
Arch Biochem Biophys
, vol.499
, pp. 40-48
-
-
Bilbao, P.S.1
Santillan, G.2
Boland, R.3
-
22
-
-
0034575678
-
Extracellular ATP-dependent suppression of proliferation and induction of differentiation of human HL-60 leukemia cells by distinct mechanisms
-
Conigrave AD, van der Weyden L, Holt L, Jiang L, Wilson P, Christopherson RI, et al. Extracellular ATP-dependent suppression of proliferation and induction of differentiation of human HL-60 leukemia cells by distinct mechanisms. Biochem Pharmacol. 2000; 60: 1585-1891.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1585-1891
-
-
Conigrave, A.D.1
van der Weyden, L.2
Holt, L.3
Jiang, L.4
Wilson, P.5
Christopherson, R.I.6
-
23
-
-
84862303668
-
Differential effects of the glycolysis inhibitor 2-deoxy-D-glucose on the activity of pro-apoptotic agents in metastatic melanoma cells, and induction of a cytoprotective autophagic response
-
Giammarioli AM, Gambardella L, Barbati C, Pietraforte D, Tinari A, Alberton M, et al. Differential effects of the glycolysis inhibitor 2-deoxy-D-glucose on the activity of pro-apoptotic agents in metastatic melanoma cells, and induction of a cytoprotective autophagic response. Int J Cancer. 2012; 131: E337-E347.
-
(2012)
Int J Cancer
, vol.131
-
-
Giammarioli, A.M.1
Gambardella, L.2
Barbati, C.3
Pietraforte, D.4
Tinari, A.5
Alberton, M.6
-
24
-
-
79251502952
-
ATP consumption promotes cancer metabolism
-
Israelsen WJ, Vander Heiden MG. ATP consumption promotes cancer metabolism. Cell. 2010; 143: 669-71.
-
(2010)
Cell
, vol.143
, pp. 669-671
-
-
Israelsen, W.J.1
Vander Heiden, M.G.2
-
25
-
-
79952227187
-
2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase
-
Wang Q, Liang B, Shirwany NA, Zou MH. 2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase. PLoS One. 2011; 6: 17234.
-
(2011)
PLoS One
, vol.6
, pp. 17234
-
-
Wang, Q.1
Liang, B.2
Shirwany, N.A.3
Zou, M.H.4
-
26
-
-
80054046029
-
Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation
-
Lunt SY, Vander Heiden MG. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu Rev Cell Dev Biol. 2011; 27: 441-464.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 441-464
-
-
Lunt, S.Y.1
Vander Heiden, M.G.2
-
27
-
-
29144467160
-
Differential sensitivity to 2-deoxy-D-glucose between two pancreatic cell lines correlates with GLUT-1 expression
-
Maher JC, Savaraj N, Priebe W, Liu H, Lampidis TJ. Differential sensitivity to 2-deoxy-D-glucose between two pancreatic cell lines correlates with GLUT-1 expression. Pancreas. 2005; 30: 34-39.
-
(2005)
Pancreas
, vol.30
, pp. 34-39
-
-
Maher, J.C.1
Savaraj, N.2
Priebe, W.3
Liu, H.4
Lampidis, T.J.5
-
28
-
-
38149063508
-
2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
-
Coleman MC, Asbury CR, Daniels D, Du J, Aykin-Burns N, Smith BJ, et al. 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free Radic Biol Med. 2008; 44: 322-331.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 322-331
-
-
Coleman, M.C.1
Asbury, C.R.2
Daniels, D.3
Du, J.4
Aykin-Burns, N.5
Smith, B.J.6
-
29
-
-
84865044204
-
Oridonin enhances antitumor activity of gemcitabine in pancreatic cancer through MAPK-p38 signaling pathway
-
Bu HQ, Luo J, Chen H, Zhang JH, Li HH, Guo HC, et al. Oridonin enhances antitumor activity of gemcitabine in pancreatic cancer through MAPK-p38 signaling pathway. Int J Oncol. 2012; 41: 949-958.
-
(2012)
Int J Oncol
, vol.41
, pp. 949-958
-
-
Bu, H.Q.1
Luo, J.2
Chen, H.3
Zhang, J.H.4
Li, H.H.5
Guo, H.C.6
-
30
-
-
0034817112
-
MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1
-
Ding XZ, Adrian TE. MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1. Biochem Biophys Res Commun. 2001; 282: 447-453.
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 447-453
-
-
Ding, X.Z.1
Adrian, T.E.2
-
31
-
-
1842420032
-
Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
-
Smith BD, Levis M, Beran M, Giles F, Kantarjian H, Berg K, et al. Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood. 2004; 103: 3669-3676.
-
(2004)
Blood
, vol.103
, pp. 3669-3676
-
-
Smith, B.D.1
Levis, M.2
Beran, M.3
Giles, F.4
Kantarjian, H.5
Berg, K.6
-
32
-
-
0001422847
-
Certain metabolic and pharmacologic effects in cancer patients given infusions of 2-deoxy-D-glucose
-
Landau BR, Laszlo J, Stengle J, Burk D. Certain metabolic and pharmacologic effects in cancer patients given infusions of 2-deoxy-D-glucose. J Natl Cancer Inst. 1958; 21: 485-494.
-
(1958)
J Natl Cancer Inst
, vol.21
, pp. 485-494
-
-
Landau, B.R.1
Laszlo, J.2
Stengle, J.3
Burk, D.4
-
33
-
-
76849111682
-
Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose
-
Blouin MJ, Zhao Y, Zakikhani M, Algire C, Piura E, Pollak M. Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose. Cancer Lett. 2010; 289: 246-253.
-
(2010)
Cancer Lett
, vol.289
, pp. 246-253
-
-
Blouin, M.J.1
Zhao, Y.2
Zakikhani, M.3
Algire, C.4
Piura, E.5
Pollak, M.6
-
35
-
-
0015525433
-
The hypothermia of hypoglycemia. Studies with 2-deoxy-D-glucose in normal human subjects and mice
-
Freinkel N, Metzger BE, Harris E, Robinson S, Mager M. The hypothermia of hypoglycemia. Studies with 2-deoxy-D-glucose in normal human subjects and mice. N Engl J Med. 1972; 287: 841-845.
-
(1972)
N Engl J Med
, vol.287
, pp. 841-845
-
-
Freinkel, N.1
Metzger, B.E.2
Harris, E.3
Robinson, S.4
Mager, M.5
-
36
-
-
65549132539
-
Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy
-
Wu H, Zhu H, Liu DX, Niu TK, Ren X, Patel R, et al. Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy. Cancer Res. 2009; 69: 2453-2460.
-
(2009)
Cancer Res
, vol.69
, pp. 2453-2460
-
-
Wu, H.1
Zhu, H.2
Liu, D.X.3
Niu, T.K.4
Ren, X.5
Patel, R.6
-
37
-
-
36749055667
-
Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis
-
Com E, Lagadec C, Page A, El Yazidi-Belkoura I, Slomianny C, Spencer A, et al. Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis. Mol Cell Proteomics. 2007; 6: 1842-1854.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 1842-1854
-
-
Com, E.1
Lagadec, C.2
Page, A.3
El Yazidi-Belkoura, I.4
Slomianny, C.5
Spencer, A.6
-
38
-
-
79951508350
-
4-Methlycatechol prevents NGF/p75(NTR)-mediated apoptosis via NGF/TrkA system in pancreatic beta cells
-
Gezginci-Oktayoglu S, Bolkent S. 4-Methlycatechol prevents NGF/p75(NTR)-mediated apoptosis via NGF/TrkA system in pancreatic beta cells. Neuropeptides. 2011; 45: 143-150.
-
(2011)
Neuropeptides
, vol.45
, pp. 143-150
-
-
Gezginci-Oktayoglu, S.1
Bolkent, S.2
-
39
-
-
66149157927
-
TrkA overexpression enhances growth and metastasis of breast cancer cells
-
Lagadec C, Meignan S, Adriaenssens E, Foveau B, Vanhecke E, Romon R, et al. TrkA overexpression enhances growth and metastasis of breast cancer cells. Oncogene. 2009; 28: 1960-1070.
-
(2009)
Oncogene
, vol.28
, pp. 1960-1970
-
-
Lagadec, C.1
Meignan, S.2
Adriaenssens, E.3
Foveau, B.4
Vanhecke, E.5
Romon, R.6
|