Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Calligaris, Sebastián D ^a   Lecanda, Manuel ^a   Solis, Felipe ^a   Ezquer, Marcelo ^a   Gutiérrez, Jaime ^b   Brandan, Enrique ^b   Leiva, Andrea ^b   Sobrevia, Luis ^b,c   Conget, Paulette ^a  

^a Facultad de Medicina Clinica Alemana Universidad del Desarrollo   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DISEASE ASSOCIATION; DISEASE MODEL; ECHOCARDIOGRAPHY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HEART CATHETERIZATION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE DP-DT; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEMODYNAMICS; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; HYPERINSULINEMIA; IMMUNOBLOTTING; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHYGMOMANOMETER; TRIACYLGLYCEROL BLOOD LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; DIABETIC CARDIOMYOPATHIES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DNA PRIMERS; ELECTROCARDIOGRAPHY; IMMUNOBLOTTING; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MYOCARDIUM; OBESITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; MUS;

EID: 84876127103     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060931     Document Type: Article

References (58)

1. Reaven GM, Chen YD, (1988) Role of insulin in regulation of lipoprotein metabolism in diabetes. Diabetes/metabolism reviews 4: 639-652.
2. Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, et al. (2003) Metabolic syndrome: epidemiology and more extensive phenotypic description. Cross-sectional data from the Bruneck Study. International journal of obesity and related metabolic disorders: journal of the International Association for the Study of Obesity 27: 1283-1289.
3. Isomaa B, Almgren P, Tuomi T, Forsen B, Lahti K, et al. (2001) Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes care 24: 683-689.
4. Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, et al. (2002) The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA: the journal of the American Medical Association 288: 2709-2716.
5. Zaragoza C, Gomez-Guerrero C, Martin-Ventura JL, Blanco-Colio L, Lavin B, et al. (2011) Animal models of cardiovascular diseases. Journal of biomedicine & biotechnology 2011: 497841.
6. Sumiyoshi M, Sakanaka M, Kimura Y, (2006) Chronic intake of high-fat and high-sucrose diets differentially affects glucose intolerance in mice. The Journal of nutrition 136: 582-587.
7. Yu Q, Larson DF, Slayback D, Lundeen TF, Baxter JH, et al. (2004) Characterization of high-salt and high-fat diets on cardiac and vascular function in mice. Cardiovascular toxicology 4: 37-46.
8. Farah V, Elased KM, Chen Y, Key MP, Cunha TS, et al. (2006) Nocturnal hypertension in mice consuming a high fructose diet. Autonomic neuroscience: basic & clinical 130: 41-50.
9. Nishina PM, Verstuyft J, Paigen B, (1990) Synthetic low and high fat diets for the study of atherosclerosis in the mouse. Journal of lipid research 31: 859-869.
10. Park SY, Cho YR, Kim HJ, Higashimori T, Danton C, et al. (2005) Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice. Diabetes 54: 3530-3540.
11. Hsueh W, Abel ED, Breslow JL, Maeda N, Davis RC, et al. (2007) Recipes for creating animal models of diabetic cardiovascular disease. Circulation research 100: 1415-1427.
12. Dailey G, (2011) Early and intensive therapy for management of hyperglycemia and cardiovascular risk factors in patients with type 2 diabetes. Clinical therapeutics 33: 665-678.
13. Nishikawa S, Yasoshima A, Doi K, Nakayama H, Uetsuka K, (2007) Involvement of sex, strain and age factors in high fat diet-induced obesity in C57BL/6J and BALB/cA mice. Experimental animals/Japanese Association for Laboratory Animal Science 56: 263-272.
14. Riccardi G, Giacco R, Rivellese AA, (2004) Dietary fat, insulin sensitivity and the metabolic syndrome. Clinical nutrition 23: 447-456.
15. Ito M, Suzuki J, Tsujioka S, Sasaki M, Gomori A, et al. (2007) Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet. Hepatology research: the official journal of the Japan Society of Hepatology 37: 50-57.
16. Ezquer M, Ezquer F, Ricca M, Allers C, Conget P, (2011) Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome. Journal of hepatology 55: 1112-1120.
17. Mattson DL, (1998) Long-term measurement of arterial blood pressure in conscious mice. The American journal of physiology 274: R564-570.
18. Westermeier F, Salomon C, Gonzalez M, Puebla C, Guzman-Gutierrez E, et al. (2011) Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium. Diabetes 60: 1677-1687.
19. Guzman-Gutierrez E, Westermeier F, Salomon C, Gonzalez M, Pardo F, et al. (2012) Insulin-increased L-arginine transport requires A(2A) adenosine receptors activation in human umbilical vein endothelium. PloS one 7: e41705.
20. Lorenz JN, Robbins J, (1997) Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse. The American journal of physiology 272: H1137-1146.
21. Calligaris S, Ricca M, Conget P, (2013) Cardiac stress test induced by dobutamine and monitored by cardiac catheterization in mice. Journal of visualized Experiments 72: 1-6.
22. Daniels A, van Bilsen M, Janssen BJ, Brouns AE, Cleutjens JP, et al. (2010) Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling. Acta physiologica 200: 11-22.
23. Rottman JN, Ni G, Brown M, (2007) Echocardiographic evaluation of ventricular function in mice. Echocardiography 24: 83-89.
24. Yin FC, Spurgeon HA, Rakusan K, Weisfeldt ML, Lakatta EG, (1982) Use of tibial length to quantify cardiac hypertrophy: application in the aging rat. The American journal of physiology 243: H941-947.
25. Mandarim-de-Lacerda CA, (2003) Stereological tools in biomedical research. Anais da Academia Brasileira de Ciencias 75: 469-486.
26. Morales MG, Cabello-Verrugio C, Santander C, Cabrera D, Goldschmeding R, et al. (2011) CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy. The Journal of pathology 225: 490-501.
27. Schmittgen TD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative C(T) method. Nature protocols 3: 1101-1108.
28. Harte RA, Kirk EA, Rosenfeld ME, LeBoeuf RC, (1999) Initiation of hyperinsulinemia and hyperleptinemia is diet dependent in C57BL/6 mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 31: 570-575.
29. Black BL, Croom J, Eisen EJ, Petro AE, Edwards CL, et al. (1998) Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice. Metabolism: clinical and experimental 47: 1354-1359.
30. Jimenez-Altayo F, Onetti Y, Heras M, Dantas AP, Vila E (2012) Western-style diet modulates contractile responses to phenylephrine differently in mesenteric arteries from senescence-accelerated prone (SAMP8) and resistant (SAMR1) mice. Age.
31. Chatterjee A, Black SM, Catravas JD, (2008) Endothelial nitric oxide (NO) and its pathophysiologic regulation. Vascular pharmacology 49: 134-140.
32. Mundy AL, Haas E, Bhattacharya I, Widmer CC, Kretz M, et al. (2007) Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity. Cardiovascular research 73: 368-375.
33. Ferrannini E, Buzzigoli G, Bonadonna R, Giorico MA, Oleggini M, et al. (1987) Insulin resistance in essential hypertension. The New England journal of medicine 317: 350-357.
34. Belin de Chantemele EJ, Mintz JD, Rainey WE, Stepp DW, (2011) Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice. Hypertension 58: 271-279.
35. Yang R, Barouch LA, (2007) Leptin signaling and obesity: cardiovascular consequences. Circulation research 101: 545-559.
36. Townsend KL, Lorenzi MM, Widmaier EP, (2008) High-fat diet-induced changes in body mass and hypothalamic gene expression in wild-type and leptin-deficient mice. Endocrine 33: 176-188.
37. Senador D, Kanakamedala K, Irigoyen MC, Morris M, Elased KM, (2009) Cardiovascular and autonomic phenotype of db/db diabetic mice. Experimental physiology 94: 648-658.
38. Drosatos K, Bharadwaj KG, Lymperopoulos A, Ikeda S, Khan R, et al. (2011) Cardiomyocyte lipids impair beta-adrenergic receptor function via PKC activation. American journal of physiology Endocrinology and metabolism 300: E489-499.
39. Wiesmann F, Ruff J, Engelhardt S, Hein L, Dienesch C, et al. (2001) Dobutamine-stress magnetic resonance microimaging in mice: acute changes of cardiac geometry and function in normal and failing murine hearts. Circulation research 88: 563-569.
40. Rutter MK, Parise H, Benjamin EJ, Levy D, Larson MG, et al. (2003) Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study. Circulation 107: 448-454.
41. Zibadi S, Vazquez R, Moore D, Larson DF, Watson RR, (2009) Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome. American journal of physiology Heart and circulatory physiology 297: H976-982.
42. Qin F, Siwik DA, Luptak I, Hou X, Wang L, et al. (2012) The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation 125: 1757-1764, S1751-1756.
43. Paul M, Poyan Mehr A, Kreutz R, (2006) Physiology of local renin-angiotensin systems. Physiological reviews 86: 747-803.
44. Aneja A, Tang WH, Bansilal S, Garcia MJ, Farkouh ME, (2008) Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options. The American journal of medicine 121: 748-757.
45. Singh VP, Le B, Khode R, Baker KM, Kumar R, (2008) Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. Diabetes 57: 3297-3306.
46. Abel ED, Litwin SE, Sweeney G, (2008) Cardiac remodeling in obesity. Physiological reviews 88: 389-419.
47. Hue L, Taegtmeyer H, (2009) The Randle cycle revisited: a new head for an old hat. American journal of physiology Endocrinology and metabolism 297: E578-591.
48. Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, et al. (2002) The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. The Journal of clinical investigation 109: 121-130.
49. Boudina S, Sena S, O'Neill BT, Tathireddy P, Young ME, et al. (2005) Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 112: 2686-2695.
50. Bugger H, Abel ED, (2010) Mitochondria in the diabetic heart. Cardiovascular research 88: 229-240.
51. Krenz M, Robbins J, (2004) Impact of beta-myosin heavy chain expression on cardiac function during stress. Journal of the American College of Cardiology 44: 2390-2397.
52. Gupta MP, (2007) Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure. Journal of molecular and cellular cardiology 43: 388-403.
53. Fan X, Wu X (2012) The first line of defense against cardiac hypertrophy. Current molecular medicine.
54. Fein FS, (1990) Diabetic cardiomyopathy. Diabetes care 13: 1169-1179.
55. Rubler S, Dlugash J, Yuceoglu YZ, Kumral T, Branwood AW, et al. (1972) New type of cardiomyopathy associated with diabetic glomerulosclerosis. The American journal of cardiology 30: 595-602.
56. Neuhaus B, Niessen CM, Mesaros A, Withers DJ, Krieg T, et al. (2012) Experimental analysis of risk factors for ulcerative dermatitis in mice. Experimental dermatology 21: 712-713.
57. Bernardi S, Severini GM, Zauli G, Secchiero P, (2012) Cell-based therapies for diabetic complications. Experimental diabetes research 2012: 872504.
58. Asghar O, Al-Sunni A, Khavandi K, Khavandi A, Withers S, et al. (2009) Diabetic cardiomyopathy. Clinical science 116: 741-760.