메뉴 건너뛰기




Volumn 50, Issue 1, 2013, Pages 204-214

The very large g protein coupled receptor (Vlgr1) in hair cells

Author keywords

G protein coupled receptor (GPCR); Hearing; Usher syndrome; Very large G protein coupled receptor (Vlgr1)

Indexed keywords

G PROTEIN COUPLED RECEPTOR; UNCLASSIFIED DRUG; VLGR1 PROTEIN;

EID: 84876115850     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9911-5     Document Type: Article
Times cited : (23)

References (98)
  • 1
    • 68349144268 scopus 로고    scopus 로고
    • Structure of the Calx-beta domain of the integrin beta4 subunit: Insights into function and cation-independent stability
    • 10.1107/S0907444909018745
    • Alonso-Garcia N, Ingles-Prieto A, Sonnenberg A, de Pereda JM (2009) Structure of the Calx-beta domain of the integrin beta4 subunit: insights into function and cation-independent stability. Acta Crystallogr D: Biol Crystallogr 65:858-871
    • (2009) Acta Crystallogr D: Biol Crystallogr , vol.65 , pp. 858-871
    • Alonso-Garcia, N.1    Ingles-Prieto, A.2    Sonnenberg, A.3    De Pereda, J.M.4
  • 2
    • 84858792464 scopus 로고    scopus 로고
    • A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
    • 22333914 1:CAS:528:DC%2BC38XitFals7o%3D 10.1038/emboj.2012.26
    • Arac D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Sudhof TC, Brunger AT (2012) A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. EMBO J 31:1364-1378
    • (2012) EMBO J , vol.31 , pp. 1364-1378
    • Arac, D.1    Boucard, A.A.2    Bolliger, M.F.3    Nguyen, J.4    Soltis, S.M.5    Sudhof, T.C.6    Brunger, A.T.7
  • 3
    • 0026326113 scopus 로고
    • Tip-link integrity and mechanical transduction in vertebrate hair cells
    • 1764247 1:CAS:528:DyaK38XhsVyltLk%3D 10.1016/0896-6273(91)90343-X
    • Assad JA, Shepherd GM, Corey DP (1991) Tip-link integrity and mechanical transduction in vertebrate hair cells. Neuron 7:985-994
    • (1991) Neuron , vol.7 , pp. 985-994
    • Assad, J.A.1    Shepherd, G.M.2    Corey, D.P.3
  • 5
    • 0030006225 scopus 로고    scopus 로고
    • Acetylcholine-induced potassium current of guinea pig outer hair cells: Its dependence on a calcium influx through nicotinic-like receptors
    • Blanchet C, Erostegui C, Sugasawa M, Dulon D (1996) Acetylcholine-induced potassium current of guinea pig outer hair cells: its dependence on a calcium influx through nicotinic-like receptors. J Neurosci 16:2574-2584 (Pubitemid 26124348)
    • (1996) Journal of Neuroscience , vol.16 , Issue.8 , pp. 2574-2584
    • Blanchet, C.1    Erostegui, C.2    Sugasawa, M.3    Dulon, D.4
  • 6
    • 79952291044 scopus 로고    scopus 로고
    • The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
    • 21262840 1:CAS:528:DC%2BC3MXitFWnur0%3D 10.1073/pnas.1019577108
    • Bolliger MF, Martinelli DC, Sudhof TC (2011) The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins. Proc Natl Acad Sci U S A 108:2534-2539
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 2534-2539
    • Bolliger, M.F.1    Martinelli, D.C.2    Sudhof, T.C.3
  • 7
    • 84855696019 scopus 로고    scopus 로고
    • Usher syndrome (sensorineural deafness and retinitis pigmentosa): Pathogenesis, molecular diagnosis and therapeutic approaches
    • 22185901 1:CAS:528:DC%2BC38XkvFyntg%3D%3D 10.1097/WCO.0b013e32834ef8b2
    • Bonnet C, El-Amraoui A (2012) Usher syndrome (sensorineural deafness and retinitis pigmentosa): pathogenesis, molecular diagnosis and therapeutic approaches. Curr Opin Neurol 25:42-49
    • (2012) Curr Opin Neurol , vol.25 , pp. 42-49
    • Bonnet, C.1    El-Amraoui, A.2
  • 12
    • 0030917971 scopus 로고    scopus 로고
    • An intramolecular disulfide bond between conserved extracellular cysteines in the gonadotropin-releasing hormone receptor is essential for binding and activation
    • DOI 10.1210/en.138.7.2800
    • Cook JV, Eidne KA (1997) An intramolecular disulfide bond between conserved extracellular cysteines in the gonadotropin-releasing hormone receptor is essential for binding and activation. Endocrinology 138:2800-2806 (Pubitemid 27258509)
    • (1997) Endocrinology , vol.138 , Issue.7 , pp. 2800-2806
    • Cook, J.V.F.1    Eidne, K.A.2
  • 14
    • 85046914504 scopus 로고    scopus 로고
    • Advances and perspectives of the architecture of hemidesmosomes: Lessons from structural biology
    • 19736524 10.4161/cam.3.4.9525
    • de Pereda JM, Ortega E, Alonso-Garcia N, Gomez-Hernandez M, Sonnenberg A (2009) Advances and perspectives of the architecture of hemidesmosomes: lessons from structural biology. Cell Adh Migr 3:361-364
    • (2009) Cell Adh Migr , vol.3 , pp. 361-364
    • De Pereda, J.M.1    Ortega, E.2    Alonso-Garcia, N.3    Gomez-Hernandez, M.4    Sonnenberg, A.5
  • 15
    • 84865063217 scopus 로고    scopus 로고
    • Defect in the gene encoding the EAR/EPTP domain-containing protein TSPEAR causes DFNB98 profound deafness
    • Delmaghani S, Aghaie A, Michalski N, Bonnet C, Weil D, Petit C (2012) Defect in the gene encoding the EAR/EPTP domain-containing protein TSPEAR causes DFNB98 profound deafness. Hum Mol Genet 21:3835-3844
    • (2012) Hum Mol Genet , vol.21 , pp. 3835-3844
    • Delmaghani, S.1    Aghaie, A.2    Michalski, N.3    Bonnet, C.4    Weil, D.5    Petit, C.6
  • 16
    • 44849117014 scopus 로고    scopus 로고
    • Beta-arrestin-mediated signaling regulates protein synthesis
    • 18276584 1:CAS:528:DC%2BD1cXksFagtrc%3D 10.1074/jbc.M710515200
    • DeWire SM, Kim J, Whalen EJ, Ahn S, Chen M, Lefkowitz RJ (2008) Beta-arrestin-mediated signaling regulates protein synthesis. J Biol Chem 283:10611-10620
    • (2008) J Biol Chem , vol.283 , pp. 10611-10620
    • Dewire, S.M.1    Kim, J.2    Whalen, E.J.3    Ahn, S.4    Chen, M.5    Lefkowitz, R.J.6
  • 17
    • 84868212231 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor and astrocyte glucose metabolism
    • 22399228 1:CAS:528:DC%2BC38XhtlKksrzJ 10.1007/s12031-012-9742-4
    • Dong JH, Chen X, Cui M, Yu X, Pang Q, Sun JP (2012) Beta2-adrenergic receptor and astrocyte glucose metabolism. J Mol Neurosci 48:456-463
    • (2012) J Mol Neurosci , vol.48 , pp. 456-463
    • Dong, J.H.1    Chen, X.2    Cui, M.3    Yu, X.4    Pang, Q.5    Sun, J.P.6
  • 19
    • 33947148611 scopus 로고    scopus 로고
    • A novel gene for Usher syndrome type 2: Mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss
    • DOI 10.1007/s00439-006-0304-0
    • Ebermann I, Scholl HP, Charbel Issa P, Becirovic E, Lamprecht J, Jurklies B, Millan JM, Aller E, Mitter D, Bolz H (2007) A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing loss. Hum Genet 121:203-211 (Pubitemid 46404454)
    • (2007) Human Genetics , vol.121 , Issue.2 , pp. 203-211
    • Ebermann, I.1    Scholl, H.P.N.2    Charbel Issa, P.3    Becirovic, E.4    Lamprecht, J.5    Jurklies, B.6    Millan, J.M.7    Aller, E.8    Mitter, D.9    Bolz, H.10
  • 23
    • 73349125449 scopus 로고    scopus 로고
    • Self-recognition and Ca2+ - Dependent carbohydrate-carbohydrate cell adhesion provide clues to the cambrian explosion
    • 19648465 1:CAS:528:DC%2BD1MXht1Oqs7fO 10.1093/molbev/msp170
    • Fernandez-Busquets X, Kornig A, Bucior I, Burger MM, Anselmetti D (2009) Self-recognition and Ca2+ - dependent carbohydrate-carbohydrate cell adhesion provide clues to the cambrian explosion. Mol Biol Evol 26:2551-2561
    • (2009) Mol Biol Evol , vol.26 , pp. 2551-2561
    • Fernandez-Busquets, X.1    Kornig, A.2    Bucior, I.3    Burger, M.M.4    Anselmetti, D.5
  • 24
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
    • DOI 10.1124/mol.63.6.1256
    • Fredriksson R, Lagerstrom MC, Lundin LG, Schioth HB (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63:1256-1272 (Pubitemid 36627220)
    • (2003) Molecular Pharmacology , vol.63 , Issue.6 , pp. 1256-1272
    • Fredriksson, R.1    Lagerstrom, M.C.2    Lundin, L.-G.3    Schioth, H.B.4
  • 27
    • 0033562398 scopus 로고    scopus 로고
    • The ankle-link antigen: An epitope sensitive to calcium chelation associated with the hair-cell surface and the calycal processes of photoreceptors
    • Goodyear R, Richardson G (1999) The ankle-link antigen: an epitope sensitive to calcium chelation associated with the hair-cell surface and the calycal processes of photoreceptors. J Neurosci 19:3761-3772 (Pubitemid 29222252)
    • (1999) Journal of Neuroscience , vol.19 , Issue.10 , pp. 3761-3772
    • Goodyear, R.1    Richardson, G.P.2
  • 28
    • 16844368993 scopus 로고    scopus 로고
    • Development and properties of stereociliary link types in hair cells of the mouse cochlea
    • DOI 10.1002/cne.20513
    • Goodyear RJ, Marcotti W, Kros CJ, Richardson GP (2005) Development and properties of stereociliary link types in hair cells of the mouse cochlea. J Comp Neurol 485:75-85 (Pubitemid 40488087)
    • (2005) Journal of Comparative Neurology , vol.485 , Issue.1 , pp. 75-85
    • Goodyear, R.J.1    Marcotti, W.2    Kros, C.J.3    Richardson, G.P.4
  • 29
    • 84859888903 scopus 로고    scopus 로고
    • Signaling property study of adhesion G-protein-coupled receptors
    • 22575658 1:CAS:528:DC%2BC38XkvFagsbo%3D 10.1016/j.febslet.2012.03.014
    • Gupte J, Swaminath G, Danao J, Tian H, Li Y, Wu X (2012) Signaling property study of adhesion G-protein-coupled receptors. FEBS Lett 586:1214-1219
    • (2012) FEBS Lett , vol.586 , pp. 1214-1219
    • Gupte, J.1    Swaminath, G.2    Danao, J.3    Tian, H.4    Li, Y.5    Wu, X.6
  • 30
    • 0028841677 scopus 로고
    • A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog
    • 7477329 1:CAS:528:DyaK2MXptlSmtbs%3D 10.1038/378212a0
    • Hall TM, Porter JA, Beachy PA, Leahy DJ (1995) A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog. Nature 378:212-216
    • (1995) Nature , vol.378 , pp. 212-216
    • Hall, T.M.1    Porter, J.A.2    Beachy, P.A.3    Leahy, D.J.4
  • 33
    • 33750947173 scopus 로고    scopus 로고
    • Retinitis pigmentosa
    • DOI 10.1016/S0140-6736(06)69740-7, PII S0140673606697407
    • Hartong DT, Berson EL, Dryja TP (2006) Retinitis pigmentosa. Lancet 368:1795-1809 (Pubitemid 44739028)
    • (2006) Lancet , vol.368 , Issue.9549 , pp. 1795-1809
    • Hartong, D.T.1    Berson, E.L.2    Dryja, T.P.3
  • 34
    • 0032976716 scopus 로고    scopus 로고
    • Development of acetylcholine-induced responses in neonatal gerbil outer hair cells
    • He DZ, Dallos P (1999) Development of acetylcholine-induced responses in neonatal gerbil outer hair cells. J Neurophysiol 81:1162-1170 (Pubitemid 29272434)
    • (1999) Journal of Neurophysiology , vol.81 , Issue.3 , pp. 1162-1170
    • He, D.Z.Z.1    Dallos, P.2
  • 35
    • 64249092433 scopus 로고    scopus 로고
    • Novel human pathological mutations. Gene symbol: GPR98. Disease: Usher syndrome 2C
    • 19320012
    • Hilgert N (2009) Novel human pathological mutations. Gene symbol: GPR98. Disease: Usher syndrome 2C. Hum Genet 125:342
    • (2009) Hum Genet , vol.125 , pp. 342
    • Hilgert, N.1
  • 36
    • 65949124017 scopus 로고    scopus 로고
    • A large deletion in GPR98 causes type IIC Usher syndrome in male and female members of an Iranian family
    • 19357116 1:CAS:528:DC%2BD1MXlt1GitL4%3D 10.1136/jmg.2008.060947
    • Hilgert N, Kahrizi K, Dieltjens N, Bazazzadegan N, Najmabadi H, Smith RJ, Van Camp G (2009) A large deletion in GPR98 causes type IIC Usher syndrome in male and female members of an Iranian family. J Med Genet 46:272-276
    • (2009) J Med Genet , vol.46 , pp. 272-276
    • Hilgert, N.1    Kahrizi, K.2    Dieltjens, N.3    Bazazzadegan, N.4    Najmabadi, H.5    Smith, R.J.6    Van Camp, G.7
  • 38
    • 77955172734 scopus 로고    scopus 로고
    • Differential expression of P2Y receptors in the rat cochlea during development
    • 20806015 1:CAS:528:DC%2BC3cXpsFSrtr0%3D 10.1007/s11302-010-9191-x
    • Huang LC, Thorne PR, Vlajkovic SM, Housley GD (2010) Differential expression of P2Y receptors in the rat cochlea during development. Purinergic Signal 6:231-248
    • (2010) Purinergic Signal , vol.6 , pp. 231-248
    • Huang, L.C.1    Thorne, P.R.2    Vlajkovic, S.M.3    Housley, G.D.4
  • 39
    • 84861315728 scopus 로고    scopus 로고
    • Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains
    • 22310662 1:CAS:528:DC%2BC38XlsVChsrk%3D 10.1128/MCB.06557-11
    • Huang YS, Chiang NY, Hu CH, Hsiao CC, Cheng KF, Tsai WP, Yona S, Stacey M, Gordon S, Chang GW et al (2012) Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains. Mol Cell Biol 32:1408-1420
    • (2012) Mol Cell Biol , vol.32 , pp. 1408-1420
    • Huang, Y.S.1    Chiang, N.Y.2    Hu, C.H.3    Hsiao, C.C.4    Cheng, K.F.5    Tsai, W.P.6    Yona, S.7    Stacey, M.8    Gordon, S.9    Chang, G.W.10
  • 40
    • 47249103800 scopus 로고    scopus 로고
    • Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway
    • 18378689 1:CAS:528:DC%2BD1cXlvFyjs7c%3D 10.1074/jbc.M708919200
    • Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N, Itoh H (2008) Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J Biol Chem 283:14469-14478
    • (2008) J Biol Chem , vol.283 , pp. 14469-14478
    • Iguchi, T.1    Sakata, K.2    Yoshizaki, K.3    Tago, K.4    Mizuno, N.5    Itoh, H.6
  • 41
    • 0032962324 scopus 로고    scopus 로고
    • Regulation of ionic currents by protein kinase A and intracellular calcium in outer hair cells isolated from the guinea-pig cochlea
    • DOI 10.1007/s004240050795
    • Jagger DJ, Ashmore JF (1999) Regulation of ionic currents by protein kinase A and intracellular calcium in outer hair cells isolated from the guinea-pig cochlea. Pflugers Arch 437:409-416 (Pubitemid 29071939)
    • (1999) Pflugers Archiv European Journal of Physiology , vol.437 , Issue.3 , pp. 409-416
    • Jagger, D.J.1    Ashmore, J.F.2
  • 42
    • 16244371351 scopus 로고    scopus 로고
    • frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC
    • DOI 10.1016/j.ygeno.2005.02.006
    • Johnson KR, Zheng QY, Weston MD, Ptacek LJ, Noben-Trauth K (2005) The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC. Genomics 85:582-590 (Pubitemid 40463694)
    • (2005) Genomics , vol.85 , Issue.5 , pp. 582-590
    • Johnson, K.R.1    Zheng, Q.Y.2    Weston, M.D.3    Ptacek, L.J.4    Noben-Trauth, K.5
  • 43
    • 0027538406 scopus 로고
    • Cellular mechanism of acetylcholine-induced response in dissociated outer hair cells of guinea-pig cochlea
    • Kakehata S, Nakagawa T, Takasaka T, Akaike N (1993) Cellular mechanism of acetylcholine-induced response in dissociated outer hair cells of guinea-pig cochlea. J Physiol 463:227-244 (Pubitemid 23120584)
    • (1993) Journal of Physiology , vol.463 , pp. 227-244
    • Kakehata, S.1    Nakagawa, T.2    Takasaka, T.3    Akaike, N.4
  • 45
    • 24144433837 scopus 로고    scopus 로고
    • Auditory deficits associated with the frings Mgr1 (Mass1) mutation in mice
    • DOI 10.1159/000086712
    • Klein BD, Fu YH, Ptacek LJ, White HS (2005) Auditory deficits associated with the frings mgr1 (mass1) mutation in mice. Dev Neurosci 27:321-332 (Pubitemid 41243220)
    • (2005) Developmental Neuroscience , vol.27 , Issue.5 , pp. 321-332
    • Klein, B.D.1    Fu, Y.-H.2    Ptacek, L.J.3    White, H.S.4
  • 46
    • 68949094195 scopus 로고    scopus 로고
    • ENaC at the cutting edge: Regulation of epithelial sodium channels by proteases
    • 19401469 1:CAS:528:DC%2BD1MXovFWrs7g%3D 10.1074/jbc.R800083200
    • Kleyman TR, Carattino MD, Hughey RP (2009) ENaC at the cutting edge: regulation of epithelial sodium channels by proteases. J Biol Chem 284:20447-20451
    • (2009) J Biol Chem , vol.284 , pp. 20447-20451
    • Kleyman, T.R.1    Carattino, M.D.2    Hughey, R.P.3
  • 47
    • 0028986712 scopus 로고
    • Ligand-induced cleavage of the V2 vasopressin receptor by a plasma membrane metalloproteinase
    • 7896781 1:CAS:528:DyaK2MXks1yju70%3D 10.1074/jbc.270.12.6476
    • Kojro E, Fahrenholz F (1995) Ligand-induced cleavage of the V2 vasopressin receptor by a plasma membrane metalloproteinase. J Biol Chem 270:6476-6481
    • (1995) J Biol Chem , vol.270 , pp. 6476-6481
    • Kojro, E.1    Fahrenholz, F.2
  • 48
    • 79955980364 scopus 로고    scopus 로고
    • A search for factors specifying tonotopy implicates DNER in hair-cell development in the chick's cochlea
    • 21497156 1:CAS:528:DC%2BC3MXmsVWru7s%3D 10.1016/j.ydbio.2011.03.031
    • Kowalik L, Hudspeth AJ (2011) A search for factors specifying tonotopy implicates DNER in hair-cell development in the chick's cochlea. Dev Biol 354:221-231
    • (2011) Dev Biol , vol.354 , pp. 221-231
    • Kowalik, L.1    Hudspeth, A.J.2
  • 49
    • 0032978949 scopus 로고    scopus 로고
    • Expression pattern of adenylyl cyclase isoforms in the inner ear of the rat by RT-PCR and immunochemical localization of calcineurin in the organ of Corti
    • DOI 10.1016/S0378-5955(99)00035-0, PII S0378595599000350
    • Kumagami H, Beitz E, Wild K, Zenner HP, Ruppersberg JP, Schultz JE (1999) Expression pattern of adenylyl cyclase isoforms in the inner ear of the rat by RT-PCR and immunochemical localization of calcineurin in the organ of Corti. Hear Res 132:69-75 (Pubitemid 29261949)
    • (1999) Hearing Research , vol.132 , Issue.1-2 , pp. 69-75
    • Kumagami, H.1    Beitz, E.2    Wild, K.3    Zenner, H.-P.4    Ruppersberg, J.P.5    Schultz, I.E.6
  • 51
    • 42149181885 scopus 로고    scopus 로고
    • Structural diversity of G protein-coupled receptors and significance for drug discovery
    • 18382464 10.1038/nrd2518
    • Lagerstrom MC, Schioth HB (2008) Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat Rev Drug Discov 7:339-357
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 339-357
    • Lagerstrom, M.C.1    Schioth, H.B.2
  • 53
    • 38949192595 scopus 로고    scopus 로고
    • A crystal clear view of the β2-adrenergic receptor
    • DOI 10.1038/nbt0208-189, PII NBT0208189
    • Lefkowitz RJ, Sun JP, Shukla AK (2008) A crystal clear view of the beta2-adrenergic receptor. Nat Biotechnol 26:189-191 (Pubitemid 351225946)
    • (2008) Nature Biotechnology , vol.26 , Issue.2 , pp. 189-191
    • Lefkowitz, R.J.1    Sun, J.-P.2    Shukla, A.K.3
  • 55
    • 77951566261 scopus 로고    scopus 로고
    • Is LGI2 the candidate gene for partial epilepsy with pericentral spikes?
    • 20183877 1:CAS:528:DC%2BC3cXisVCgtbs%3D 10.1142/S0219720010004550
    • Limviphuvadh V, Chua LL, Eisenhaber F, Adhikari S, Maurer-Stroh S (2010a) Is LGI2 the candidate gene for partial epilepsy with pericentral spikes? J Bioinform Comput Biol 8:117-127
    • (2010) J Bioinform Comput Biol , vol.8 , pp. 117-127
    • Limviphuvadh, V.1    Chua, L.L.2    Eisenhaber, F.3    Adhikari, S.4    Maurer-Stroh, S.5
  • 56
    • 77956919288 scopus 로고    scopus 로고
    • Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2
    • 20863412 10.1186/1471-2091-11-39
    • Limviphuvadh V, Chua LL, Rahim RA, Eisenhaber F, Maurer-Stroh S, Adhikari S (2010b) Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2. BMC Biochem 11:39
    • (2010) BMC Biochem , vol.11 , pp. 39
    • Limviphuvadh, V.1    Chua, L.L.2    Rahim, R.A.3    Eisenhaber, F.4    Maurer-Stroh, S.5    Adhikari, S.6
  • 57
    • 3843101589 scopus 로고    scopus 로고
    • Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif
    • DOI 10.1074/jbc.M402974200
    • Lin HH, Chang GW, Davies JQ, Stacey M, Harris J, Gordon S (2004) Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif. J Biol Chem 279:31823-31832 (Pubitemid 39037855)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.30 , pp. 31823-31832
    • Lin, H.-H.1    Chang, G.-W.2    Davies, J.Q.3    Stacey, M.4    Harris, J.5    Gordon, S.6
  • 58
    • 2342653563 scopus 로고    scopus 로고
    • q/11 Association
    • DOI 10.1091/mbc.E03-12-0886
    • Little KD, Hemler ME, Stipp CS (2004) Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association. Mol Biol Cell 15:2375-2387 (Pubitemid 38580653)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.5 , pp. 2375-2387
    • Little, K.D.1    Hemler, M.E.2    Stipp, C.S.3
  • 59
    • 57749172475 scopus 로고    scopus 로고
    • Structural recognition and functional activation of FcgammaR by innate pentraxins
    • 19011614 1:CAS:528:DC%2BD1cXhsFWmsLfM 10.1038/nature07468
    • Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD (2008) Structural recognition and functional activation of FcgammaR by innate pentraxins. Nature 456:989-992
    • (2008) Nature , vol.456 , pp. 989-992
    • Lu, J.1    Marnell, L.L.2    Marjon, K.D.3    Mold, C.4    Du Clos, T.W.5    Sun, P.D.6
  • 61
    • 2942633028 scopus 로고    scopus 로고
    • Loss of the transmembrane and cytoplasmic domains of the very large G-protein-coupled receptor-1 (VLGR1 or Mass1) causes audiogenic seizures in mice
    • DOI 10.1016/j.mcn.2004.02.005, PII S1044743104000405
    • McMillan DR, White PC (2004) Loss of the transmembrane and cytoplasmic domains of the very large G-protein-coupled receptor-1 (VLGR1 or Mass1) causes audiogenic seizures in mice. Mol Cell Neurosci 26:322-329 (Pubitemid 38781088)
    • (2004) Molecular and Cellular Neuroscience , vol.26 , Issue.2 , pp. 322-329
    • McMillan, D.R.1    White, P.C.2
  • 62
    • 79960795399 scopus 로고    scopus 로고
    • Studies on the very large G protein-coupled receptor: From initial discovery to determining its role in sensorineural deafness in higher animals
    • 21618827 1:CAS:528:DC%2BC38XhtVeltLzM 10.1007/978-1-4419-7913-1-6
    • McMillan DR, White PC (2010) Studies on the very large G protein-coupled receptor: from initial discovery to determining its role in sensorineural deafness in higher animals. Adv Exp Med Biol 706:76-86
    • (2010) Adv Exp Med Biol , vol.706 , pp. 76-86
    • McMillan, D.R.1    White, P.C.2
  • 63
    • 0037016757 scopus 로고    scopus 로고
    • Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system
    • DOI 10.1074/jbc.M108929200
    • McMillan DR, Kayes-Wandover KM, Richardson JA, White PC (2002) Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system. J Biol Chem 277:785-792 (Pubitemid 34952119)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.1 , pp. 785-792
    • Randy McMillan, D.1    Kayes-Wandover, K.M.2    Richardson, J.A.3    White, P.C.4
  • 65
    • 79952152590 scopus 로고    scopus 로고
    • Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component
    • 21360619 1:CAS:528:DC%2BC3MXisV2jsbk%3D 10.1002/jmr.1090
    • Mikolajek H, Kolstoe SE, Pye VE, Mangione P, Pepys MB, Wood SP (2011) Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J Mol Recognit 24:371-377
    • (2011) J Mol Recognit , vol.24 , pp. 371-377
    • Mikolajek, H.1    Kolstoe, S.E.2    Pye, V.E.3    Mangione, P.4    Pepys, M.B.5    Wood, S.P.6
  • 68
    • 51049084661 scopus 로고    scopus 로고
    • Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor
    • 18534983 1:CAS:528:DC%2BD1cXoslWrtL8%3D 10.1074/jbc.M800431200
    • Nelson CD, Kovacs JJ, Nobles KN, Whalen EJ, Lefkowitz RJ (2008) Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor. J Biol Chem 283:21093-21101
    • (2008) J Biol Chem , vol.283 , pp. 21093-21101
    • Nelson, C.D.1    Kovacs, J.J.2    Nobles, K.N.3    Whalen, E.J.4    Lefkowitz, R.J.5
  • 69
    • 0033766032 scopus 로고    scopus 로고
    • Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain
    • 10976914 1:CAS:528:DC%2BD3cXmt1Onurw%3D 10.1210/me.14.9.1351
    • Nikkila H, McMillan DR, Nunez BS, Pascoe L, Curnow KM, White PC (2000) Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain. Mol Endocrinol 14:1351-1364
    • (2000) Mol Endocrinol , vol.14 , pp. 1351-1364
    • Nikkila, H.1    McMillan, D.R.2    Nunez, B.S.3    Pascoe, L.4    Curnow, K.M.5    White, P.C.6
  • 70
    • 84867772612 scopus 로고    scopus 로고
    • Adhesion G Protein-Coupled Receptors: Signaling, Pharmacology & Mechanisms of Activation
    • Paavola KJ, Hall RA (2012) Adhesion G Protein-Coupled Receptors: Signaling, Pharmacology & Mechanisms of Activation. Mol Pharmacol 82:777-783
    • (2012) Mol Pharmacol , vol.82 , pp. 777-783
    • Paavola, K.J.1    Hall, R.A.2
  • 71
    • 80051703577 scopus 로고    scopus 로고
    • The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity
    • 21708946 1:CAS:528:DC%2BC3MXhtVWgsb3F 10.1074/jbc.M111.247973
    • Paavola KJ, Stephenson JR, Ritter SL, Alter SP, Hall RA (2011) The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. J Biol Chem 286:28914-28921
    • (2011) J Biol Chem , vol.286 , pp. 28914-28921
    • Paavola, K.J.1    Stephenson, J.R.2    Ritter, S.L.3    Alter, S.P.4    Hall, R.A.5
  • 73
    • 0032498234 scopus 로고    scopus 로고
    • Protein splicing of inteins and hedgehog autoproteolysis: Structure, function, and evolution
    • DOI 10.1016/S0092-8674(00)80892-2
    • Perler FB (1998) Protein splicing of inteins and hedgehog autoproteolysis: structure, function, and evolution. Cell 92:1-4 (Pubitemid 28053291)
    • (1998) Cell , vol.92 , Issue.1 , pp. 1-4
    • Perler, F.B.1
  • 74
    • 0028948811 scopus 로고
    • The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
    • 7885476 1:CAS:528:DyaK2MXksFKmsr4%3D 10.1038/374363a0
    • Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA (1995) The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 374:363-366
    • (1995) Nature , vol.374 , pp. 363-366
    • Porter, J.A.1    Von Kessler, D.P.2    Ekker, S.C.3    Young, K.E.4    Lee, J.J.5    Moses, K.6    Beachy, P.A.7
  • 78
    • 0037098957 scopus 로고    scopus 로고
    • A common protein interaction domain links two recently identified epilepsy genes
    • Scheel H, Tomiuk S, Hofmann K (2002) A common protein interaction domain links two recently identified epilepsy genes. Hum Mol Genet 11:1757-1762 (Pubitemid 34812096)
    • (2002) Human Molecular Genetics , vol.11 , Issue.15 , pp. 1757-1762
    • Scheel, H.1    Tomiuk, S.2    Hofmann, K.3
  • 79
    • 18244362033 scopus 로고    scopus 로고
    • The GRAFS classification system of G-protein coupled receptors in comparative perspective
    • DOI 10.1016/j.ygcen.2004.12.018
    • Schioth HB, Fredriksson R (2005) The GRAFS classification system of G-protein coupled receptors in comparative perspective. Gen Comp Endocrinol 142:94-101 (Pubitemid 40626718)
    • (2005) General and Comparative Endocrinology , vol.142 , Issue.SPEC. ISS. 1-2 , pp. 94-101
    • Schioth, H.B.1    Fredriksson, R.2
  • 81
    • 84863660179 scopus 로고    scopus 로고
    • Wnt-responsive lgr5-expressing stem cells are hair cell progenitors in the cochlea
    • 22787049 1:CAS:528:DC%2BC38XhtVGlsb3M 10.1523/JNEUROSCI.1064-12.2012
    • Shi F, Kempfle JS, Edge AS (2012) Wnt-responsive lgr5-expressing stem cells are hair cell progenitors in the cochlea. J Neurosci 32:9639-9648
    • (2012) J Neurosci , vol.32 , pp. 9639-9648
    • Shi, F.1    Kempfle, J.S.2    Edge, A.S.3
  • 82
    • 42449139192 scopus 로고    scopus 로고
    • Crystallizing thinking about the β2-adrenergic receptor
    • DOI 10.1124/mol.108.045849
    • Shukla AK, Sun JP, Lefkowitz RJ (2008) Crystallizing thinking about the beta2-adrenergic receptor. Mol Pharmacol 73:1333-1338 (Pubitemid 351574821)
    • (2008) Molecular Pharmacology , vol.73 , Issue.5 , pp. 1333-1338
    • Shukla, A.K.1    Sun, J.-P.2    Lefkowitz, R.J.3
  • 83
    • 0035974897 scopus 로고    scopus 로고
    • A novel gene causing a mendelian audiogenic mouse epilepsy
    • DOI 10.1016/S0896-6273(01)00397-X
    • Skradski SL, Clark AM, Jiang H, White HS, Fu YH, Ptacek LJ (2001) A novel gene causing a mendelian audiogenic mouse epilepsy. Neuron 31:537-544 (Pubitemid 32835109)
    • (2001) Neuron , vol.31 , Issue.4 , pp. 537-544
    • Skradski, S.L.1    Clark, A.M.2    Jiang, H.3    White H.Steve4    Fu, Y.-H.5    Ptacek, L.J.6
  • 84
    • 0141923864 scopus 로고    scopus 로고
    • The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans
    • DOI 10.1182/blood-2002-11-3540
    • Stacey M, Chang GW, Davies JQ, Kwakkenbos MJ, Sanderson RD, Hamann J, Gordon S, Lin HH (2003) The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans. Blood 102:2916-2924 (Pubitemid 37248865)
    • (2003) Blood , vol.102 , Issue.8 , pp. 2916-2924
    • Stacey, M.1    Chang, G.-W.2    Davies, J.Q.3    Kwakkenbos, M.J.4    Sanderson, R.D.5    Hamann, J.6    Gordon, S.7    Lin, H.-H.8
  • 85
    • 2442760219 scopus 로고    scopus 로고
    • Acetylcholine-induced phosphorylation in isolated outer hair cells
    • DOI 10.1080/00016489950181639
    • Szonyi M, Csermely P, Sziklai I (1999) Acetylcholine-induced phosphorylation in isolated outer hair cells. Acta Otolaryngol 119:185-188 (Pubitemid 29177065)
    • (1999) Acta Oto-Laryngologica , vol.119 , Issue.2 , pp. 185-188
    • Szonyi, M.1    Csermely, P.2    Sziklai, I.3
  • 88
    • 70349694069 scopus 로고    scopus 로고
    • Adenosine and the auditory system
    • 20190966 1:CAS:528:DC%2BD1MXhsVSksrnL 10.2174/157015909789152155
    • Vlajkovic SM, Housley GD, Thorne PR (2009) Adenosine and the auditory system. Curr Neuropharmacol 7:246-256
    • (2009) Curr Neuropharmacol , vol.7 , pp. 246-256
    • Vlajkovic, S.M.1    Housley, G.D.2    Thorne, P.R.3
  • 90
    • 77449124007 scopus 로고    scopus 로고
    • Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions
    • 19815561 1:CAS:528:DC%2BC3cXlvFCltA%3D%3D 10.1074/jbc.M109.059162
    • Wu M, Le HD, Wang M, Yurkov V, Omelchenko A, Hnatowich M, Nix J, Hryshko LV, Zheng L (2010) Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions. J Biol Chem 285:2554-2561
    • (2010) J Biol Chem , vol.285 , pp. 2554-2561
    • Wu, M.1    Le, H.D.2    Wang, M.3    Yurkov, V.4    Omelchenko, A.5    Hnatowich, M.6    Nix, J.7    Hryshko, L.V.8    Zheng, L.9
  • 91
    • 77956998735 scopus 로고    scopus 로고
    • Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)
    • 20686112 1:CAS:528:DC%2BC3cXhtFSnsb%2FI 10.1073/pnas.1008461107
    • Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villen J, Haas W, Kovacs JJ, Shukla AK, Hara MR et al (2010) Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci U S A 107:15299-15304
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15299-15304
    • Xiao, K.1    Sun, J.2    Kim, J.3    Rajagopal, S.4    Zhai, B.5    Villen, J.6    Haas, W.7    Kovacs, J.J.8    Shukla, A.K.9    Hara, M.R.10
  • 95
    • 77953213409 scopus 로고    scopus 로고
    • Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss
    • 20502675 10.1371/journal.pgen.1000955
    • Yang J, Liu X, Zhao Y, Adamian M, Pawlyk B, Sun X, McMillan DR, Liberman MC, Li T (2010) Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss. PLoS Genet 6:e1000955
    • (2010) PLoS Genet , vol.6 , pp. 1000955
    • Yang, J.1    Liu, X.2    Zhao, Y.3    Adamian, M.4    Pawlyk, B.5    Sun, X.6    McMillan, D.R.7    Liberman, M.C.8    Li, T.9
  • 96
    • 77952477811 scopus 로고    scopus 로고
    • Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability
    • 20130004 1:CAS:528:DC%2BC3cXksFKns74%3D 10.1093/hmg/ddq047
    • Yu YE, Wen L, Silva J, Li Z, Head K, Sossey-Alaoui K, Pao A, Mei L, Cowell JK (2010) Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability. Hum Mol Genet 19:1702-1711
    • (2010) Hum Mol Genet , vol.19 , pp. 1702-1711
    • Yu, Y.E.1    Wen, L.2    Silva, J.3    Li, Z.4    Head, K.5    Sossey-Alaoui, K.6    Pao, A.7    Mei, L.8    Cowell, J.K.9
  • 97
    • 84866972312 scopus 로고    scopus 로고
    • Regulated Vesicular Trafficking of Specific PCDH15 and VLGR1 Variants in Auditory Hair Cells
    • 23035094 1:CAS:528:DC%2BC38XhsVyqsrjM 10.1523/JNEUROSCI.1242-12.2012
    • Zallocchi M, Delimont D, Meehan DT, Cosgrove D (2012a) Regulated Vesicular Trafficking of Specific PCDH15 and VLGR1 Variants in Auditory Hair Cells. J Neurosci 32:13841-13859
    • (2012) J Neurosci , vol.32 , pp. 13841-13859
    • Zallocchi, M.1    Delimont, D.2    Meehan, D.T.3    Cosgrove, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.