Structure activity relationship of plumbagin in BRCA1 related cancer cells

Molecular Carcinogenesis

Volumn 52, Issue 5, 2013, Pages 392-403

  Thasni, K A ^a   Ratheeshkumar, T ^a   Rojini, G ^a   Sivakumar, K C ^a   Nair, Rakesh Sathish ^a   Srinivas, G ^b   Banerji, Asoke ^c   Somasundaram, Veena ^a   Srinivas, Priya ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

^b SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

^c School of Biotechnology   (India)

Author keywords

BRCA1; Microarray; Plumbagin; Quinones; Suppression subtractive hybridization

Indexed keywords

ANTINEOPLASTIC AGENT; BRCA1 PROTEIN; DEATH RECEPTOR 5; ESTROGEN RECEPTOR; PLUMBAGIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CONTROLLED STUDY; DNA BINDING; DRUG MECHANISM; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DOCKING; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; SUPPRESSION SUBTRACTIVE HYBRIDIZATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BRCA1 PROTEIN; BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; DRUG SCREENING ASSAYS, ANTITUMOR; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE KNOCKOUT TECHNIQUES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR DOCKING SIMULATION; NAPHTHOQUINONES; OVARIAN NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; RESPONSE ELEMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTOME;

EID: 84876104292     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.21877     Document Type: Article

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