메뉴 건너뛰기




Volumn 147, Issue 1, 2013, Pages 164-173

Purified active lotus plumule (Nelumbo nucifera Gaertn) polysaccharides exert anti-inflammatory activity through decreasing Toll-like receptor-2 and -4 expressions using mouse primary splenocytes

Author keywords

Anti inflammation; Cytokines; Primary splenocytes; Purified active lotus plumule polysaccharides; Toll like receptors

Indexed keywords

ANTIINFLAMMATORY AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LOTUS PLUMULE POLYSACCHARIDE; MESSENGER RNA; POLYSACCHARIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84876101156     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.02.028     Document Type: Article
Times cited : (40)

References (32)
  • 1
    • 33751042265 scopus 로고    scopus 로고
    • Toll-like receptors (TLRs) and immune disorders
    • DOI 10.1007/s10156-006-0477-4
    • S. Akashi-Takamura, and K. Miyake Toll-like receptors (TLRs) and immune disorders Journal of Infection and Chemotherapy 12 2006 233 240 (Pubitemid 44760501)
    • (2006) Journal of Infection and Chemotherapy , vol.12 , Issue.5 , pp. 233-240
    • Akashi-Takamura, S.1    Miyake, K.2
  • 4
    • 0034650930 scopus 로고    scopus 로고
    • Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing toll-like receptors
    • E. Cario, I.M. Rosenberg, S.L. Brandwein, P.L. Beck, H.C. Reinecker, and D.K. Podolsky Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors Journal of Immunology 164 2000 966 972 (Pubitemid 30043724)
    • (2000) Journal of Immunology , vol.164 , Issue.2 , pp. 966-972
    • Cario, E.1    Rosenberg, I.M.2    Brandwein, S.L.3    Beck, P.L.4    Reinecker, H.-C.5    Podolsky, D.K.6
  • 5
    • 84857781885 scopus 로고    scopus 로고
    • An immunostimulatory polysaccharide (SCP-IIa) from the fruit of Schisandra chinensis (Turcz.) Baill
    • Y. Chen, J. Tang, X. Wang, F. Sun, and S. Liang An immunostimulatory polysaccharide (SCP-IIa) from the fruit of Schisandra chinensis (Turcz.) Baill International Journal of Biological Macromolecules 50 2012 844 848
    • (2012) International Journal of Biological Macromolecules , vol.50 , pp. 844-848
    • Chen, Y.1    Tang, J.2    Wang, X.3    Sun, F.4    Liang, S.5
  • 6
    • 84355161540 scopus 로고    scopus 로고
    • Berberine, an isoquinoline alkaloid, inhibits streptozotocin-induced apoptosis in mouse pancreatic islets through down-regulating Bax/Bcl-2 gene expression ratio
    • W.H. Chueh, and J.Y. Lin Berberine, an isoquinoline alkaloid, inhibits streptozotocin-induced apoptosis in mouse pancreatic islets through down-regulating Bax/Bcl-2 gene expression ratio Food Chemistry 132 2012 252 260
    • (2012) Food Chemistry , vol.132 , pp. 252-260
    • Chueh, W.H.1    Lin, J.Y.2
  • 7
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • DOI 10.1038/nature01326
    • J. Cohen The immunopathogenesis of sepsis Nature 420 2002 885 891 (Pubitemid 36019643)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 885-891
    • Cohen, J.1
  • 8
    • 1542358743 scopus 로고    scopus 로고
    • Toll-like receptors 2 and 4, and acute phase cytokine gene expression in dexamethasone and growth hormone treated dairy calves
    • DOI 10.1016/j.vetimm.2003.10.009, PII S0165242703002575
    • S.D. Eicher, K.A. McMunn, H.M. Hammon, and S.S. Donkin Toll-like receptors 2 and 4, and acute phase cytokine gene expression in dexamethasone and growth hormone treated dairy calves Veterinary Immunology and Immunopathology 98 2004 115 125 (Pubitemid 38317025)
    • (2004) Veterinary Immunology and Immunopathology , vol.98 , Issue.3-4 , pp. 115-125
    • Eicher, S.D.1    McMunn, K.A.2    Hammon, H.M.3    Donkin, S.S.4
  • 9
    • 0035253370 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide and IFN-γ induce toll-like receptor 2 and toll-like receptor 4 expression in human endothelial cells: Role of NF-κB activation
    • E. Faure, L. Thomas, H. Xu, A. Medvedev, O. Equils, and M. Arditi Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation Journal of Immunology 166 2001 2018 2024 (Pubitemid 32114690)
    • (2001) Journal of Immunology , vol.166 , Issue.3 , pp. 2018-2024
    • Faure, E.1    Thomas, L.2    Xu, H.3    Medvedev, A.E.4    Equils, O.5    Arditi, M.6
  • 10
    • 0242552753 scopus 로고    scopus 로고
    • Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: Roles of the receptor complex
    • DOI 10.1016/j.pharmthera.2003.08.003
    • M. Fujihara, M. Muroi, K. Tanamoto, T. Suzuki, H. Azuma, and H. Ikeda Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex Pharmacology and Therapeutics 100 2003 171 194 (Pubitemid 37377912)
    • (2003) Pharmacology and Therapeutics , vol.100 , Issue.2 , pp. 171-194
    • Fujihara, M.1    Muroi, M.2    Tanamoto, K.-I.3    Suzuki, T.4    Azuma, H.5    Ikeda, H.6
  • 12
    • 84860327211 scopus 로고    scopus 로고
    • Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation
    • J. Hoppstadter, B. Diesel, L.K. Eifler, T. Schmid, B. Brune, and P.A. Kiemer Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation European Journal of Immunology 42 2012 1282 1293
    • (2012) European Journal of Immunology , vol.42 , pp. 1282-1293
    • Hoppstadter, J.1    Diesel, B.2    Eifler, L.K.3    Schmid, T.4    Brune, B.5    Kiemer, P.A.6
  • 13
    • 79960675607 scopus 로고    scopus 로고
    • Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties
    • Q. Liang, Q. Wu, J. Jiang, J. Duan, C. Wang, M.D. Smith, H. Lu, Q. Wang, P. Nagarkatti, and D. Fan Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties Journal of Biological Chemistry 286 2011 26470 26479
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 26470-26479
    • Liang, Q.1    Wu, Q.2    Jiang, J.3    Duan, J.4    Wang, C.5    Smith, M.D.6    Lu, H.7    Wang, Q.8    Nagarkatti, P.9    Fan, D.10
  • 14
    • 78149406549 scopus 로고    scopus 로고
    • Characterisation of the chemical composition and in vitro anti-inflammation assessment of a novel lotus (Nelumbo nucifera Gaertn) plumule polysaccharide
    • C.H. Liao, S.J. Guo, and J.Y. Lin Characterisation of the chemical composition and in vitro anti-inflammation assessment of a novel lotus (Nelumbo nucifera Gaertn) plumule polysaccharide Food Chemistry 125 2011 930 935
    • (2011) Food Chemistry , vol.125 , pp. 930-935
    • Liao, C.H.1    Guo, S.J.2    Lin, J.Y.3
  • 15
    • 79959943999 scopus 로고    scopus 로고
    • Lotus (Nelumbo nucifera Gaertn) plumule polysaccharide protects the spleen and liver from spontaneous inflammation in non-obese diabetic mice by modulating pro-/anti-inflammatory cytokine gene expression
    • C.H. Liao, and J.Y. Lin Lotus (Nelumbo nucifera Gaertn) plumule polysaccharide protects the spleen and liver from spontaneous inflammation in non-obese diabetic mice by modulating pro-/anti-inflammatory cytokine gene expression Food Chemistry 129 2011 245 252
    • (2011) Food Chemistry , vol.129 , pp. 245-252
    • Liao, C.H.1    Lin, J.Y.2
  • 16
    • 84865709233 scopus 로고    scopus 로고
    • Purification, partial characterization and anti-inflammatory characteristics of lotus (Nelumbo nucifera Gaertn) plumule polysaccharides
    • C.H. Liao, and J.Y. Lin Purification, partial characterization and anti-inflammatory characteristics of lotus (Nelumbo nucifera Gaertn) plumule polysaccharides Food Chemistry 135 2012 1818 1827
    • (2012) Food Chemistry , vol.135 , pp. 1818-1827
    • Liao, C.H.1    Lin, J.Y.2
  • 17
    • 13844294161 scopus 로고    scopus 로고
    • Amaranthus spinosus water extract directly stimulates proliferation of B lymphocyte in vitro
    • B.F. Lin, B.L. Chiang, and J.Y. Lin Amaranthus spinosus water extract directly stimulates proliferation of B lymphocyte in vitro International Immunopharmacology 5 2005 711 722
    • (2005) International Immunopharmacology , vol.5 , pp. 711-722
    • Lin, B.F.1    Chiang, B.L.2    Lin, J.Y.3
  • 18
    • 33846639248 scopus 로고    scopus 로고
    • Effects of lotus plumule supplementation before and following systemic administration of lipopolysaccharide on the splenocyte responses of BALB/c mice
    • J.Y. Lin, Y.S. Lai, C.J. Liu, and A.R. Wu Effects of lotus plumule supplementation before and following systemic administration of lipopolysaccharide on the splenocyte responses of BALB/c mice Food and Chemical Toxicology 45 2007 486 493
    • (2007) Food and Chemical Toxicology , vol.45 , pp. 486-493
    • Lin, J.Y.1    Lai, Y.S.2    Liu, C.J.3    Wu, A.R.4
  • 19
    • 78651085721 scopus 로고    scopus 로고
    • Five bitter compounds display different anti-inflammatory effects through modulating cytokine secretion using mouse primary splenocytes in vitro
    • W.C. Lin, and J.Y. Lin Five bitter compounds display different anti-inflammatory effects through modulating cytokine secretion using mouse primary splenocytes in vitro Journal of Agricultural and Food Chemistry 59 2011 184 192
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , pp. 184-192
    • Lin, W.C.1    Lin, J.Y.2
  • 20
    • 81855201902 scopus 로고    scopus 로고
    • Berberine down-regulates the Th1/Th2 cytokine gene expression ratio in mouse primary splenocytes in the absence or presence of lipopolysaccharide in a preventive manner
    • W.C. Lin, and J.Y. Lin Berberine down-regulates the Th1/Th2 cytokine gene expression ratio in mouse primary splenocytes in the absence or presence of lipopolysaccharide in a preventive manner International Immunopharmacology 11 2011 1984 1990
    • (2011) International Immunopharmacology , vol.11 , pp. 1984-1990
    • Lin, W.C.1    Lin, J.Y.2
  • 21
    • 0034637439 scopus 로고    scopus 로고
    • The lipopolysaccharide-activated Toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes
    • DOI 10.1074/jbc.M002137200
    • Y. Lin, H. Lee, A.H. Berg, M.P. Lisanti, L. Shapiro, and P.E. Scherer The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes Journal of Biological Chemistry 275 2000 24255 24263 (Pubitemid 30626513)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.32 , pp. 24255-24263
    • Lin, Y.1    Lee, H.2    Berg, A.H.3    Lisanti, M.P.4    Shapiro, L.5    Scherer, P.E.6
  • 22
    • 70350568185 scopus 로고    scopus 로고
    • Immunomodulation of Rheum tanguticum polysaccharide (RTP) on the immunosuppressive effects of dexamethasone (DEX) on the treatment of colitis in rats induced by 2,4,6-trinitrobenzene sulfonic acid
    • L. Liu, S. Yuan, Y. Long, Z. Guo, Y. Sun, Y. Li, Y. Niu, C. Li, and Q. Mei Immunomodulation of Rheum tanguticum polysaccharide (RTP) on the immunosuppressive effects of dexamethasone (DEX) on the treatment of colitis in rats induced by 2,4,6-trinitrobenzene sulfonic acid International Immunopharmacology 9 2009 1568 1577
    • (2009) International Immunopharmacology , vol.9 , pp. 1568-1577
    • Liu, L.1    Yuan, S.2    Long, Y.3    Guo, Z.4    Sun, Y.5    Li, Y.6    Niu, Y.7    Li, C.8    Mei, Q.9
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method Methods 25 2001 402 408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 24
    • 43049179999 scopus 로고    scopus 로고
    • LPS/TLR4 signal transduction pathway
    • Y.C. Lu, W.C. Yeh, and P.S. Ohashi LPS/TLR4 signal transduction pathway Cytokine 42 2008 145 151
    • (2008) Cytokine , vol.42 , pp. 145-151
    • Lu, Y.C.1    Yeh, W.C.2    Ohashi, P.S.3
  • 25
    • 0034670047 scopus 로고    scopus 로고
    • Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
    • T. Matsuguchi, T. Musikacharoen, T. Ogawa, and Y. Yoshikai Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages Journal of Immunology 165 2000 5767 5772
    • (2000) Journal of Immunology , vol.165 , pp. 5767-5772
    • Matsuguchi, T.1    Musikacharoen, T.2    Ogawa, T.3    Yoshikai, Y.4
  • 26
    • 0034651637 scopus 로고    scopus 로고
    • Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes
    • T. Matsuguchi, K. Takagi, T. Musikacharoen, and Y. Yoshikai Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes Blood 95 2000 1378 1385 (Pubitemid 30099850)
    • (2000) Blood , vol.95 , Issue.4 , pp. 1378-1385
    • Matsuguchi, T.1    Takagi, K.2    Musikacharoen, T.3    Yoshikai, Y.4
  • 27
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • DOI 10.1126/science.1078231
    • C. Pasare, and R. Medzhitov Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells Science 299 2003 1033 1036 (Pubitemid 36222922)
    • (2003) Science , vol.299 , Issue.5609 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 30
    • 0033969788 scopus 로고    scopus 로고
    • Human toll-like receptors 2 and 4 are targets for deactivation of mononuclear phagocytes by interleukin-4
    • DOI 10.1016/S0165-2478(99)00168-6, PII S0165247899001686
    • H. Staege, A. Schaffner, and M. Schneemann Human toll-like receptors 2 and 4 are targets for deactivation of mononuclear phagocytes by interleukin-4 Immunology Letters 71 2000 1 3 (Pubitemid 30068604)
    • (2000) Immunology Letters , vol.71 , Issue.1 , pp. 1-3
    • Staege, H.1    Schaffner, A.2    Schneemann, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.