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Volumn 108, Issue 3, 2013, Pages

Activation of RISK and SAFE pathways is not involved in the effects of Cx43 deficiency on tolerance to ischemia-reperfusion injury and preconditioning protection

Author keywords

Connexin 43; Infarction; Ischemia reperfusion; Preconditioning

Indexed keywords

AFIMOXIFENE; CONNEXIN 43; DIAZOXIDE; GLYCOGEN SYNTHASE KINASE 3BETA; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; STAT3 PROTEIN;

EID: 84876097849     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-013-0351-3     Document Type: Article
Times cited : (36)

References (40)
  • 1
    • 79952150276 scopus 로고    scopus 로고
    • Calcium-induced permeability transition in rat brain mitochondria is promoted by carbenoxolone through targeting connexin43
    • 10.1152/ajpcell.00061.2010 21148408 10.1152/ajpcell.00061.2010 1:CAS:528:DC%2BC3MXjs1Grs7c%3D
    • Azarashvili T, Baburina Y, Grachev D, Krestinina O, Evtodienko Y, Stricker R, Reiser G (2011) Calcium-induced permeability transition in rat brain mitochondria is promoted by carbenoxolone through targeting connexin43. Am J Physiol Cell Physiol 300:C707-C720. doi: 10.1152/ajpcell.00061.2010
    • (2011) Am J Physiol Cell Physiol , vol.300
    • Azarashvili, T.1    Baburina, Y.2    Grachev, D.3    Krestinina, O.4    Evtodienko, Y.5    Stricker, R.6    Reiser, G.7
  • 3
    • 78649324875 scopus 로고    scopus 로고
    • Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
    • 10.1007/s00395-010-0124-1 20960209 10.1007/s00395-010-0124-1 1:CAS:528:DC%2BC3cXhtlClu7bP
    • Boengler K, Hilfiker-Kleiner D, Heusch G, Schulz R (2010) Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion. Basic Res Cardiol 105:771-785. doi: 10.1007/s00395-010-0124-1
    • (2010) Basic Res Cardiol , vol.105 , pp. 771-785
    • Boengler, K.1    Hilfiker-Kleiner, D.2    Heusch, G.3    Schulz, R.4
  • 5
    • 79551675869 scopus 로고    scopus 로고
    • Ischemic postconditioning: From receptor to end-effector
    • 10.1089/ars.2010.3318 20518705 10.1089/ars.2010.3318 1:CAS:528: DC%2BC3MXht1yktrg%3D
    • Cohen MV, Downey JM (2011) Ischemic postconditioning: from receptor to end-effector. Antioxid Redox Signal 14:821-831. doi: 10.1089/ars.2010.3318
    • (2011) Antioxid Redox Signal , vol.14 , pp. 821-831
    • Cohen, M.V.1    Downey, J.M.2
  • 6
    • 42049119846 scopus 로고    scopus 로고
    • Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts
    • 10.1096/fj.07-8974com 17984180 10.1096/fj.07-8974com 1:CAS:528: DC%2BD1cXktlWntrg%3D
    • Danik SB, Rosner G, Lader J, Gutstein DE, Fishman GI, Morley GE (2008) Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts. FASEB J 22:1204-1212. doi: 10.1096/fj.07-8974com
    • (2008) FASEB J , vol.22 , pp. 1204-1212
    • Danik, S.B.1    Rosner, G.2    Lader, J.3    Gutstein, D.E.4    Fishman, G.I.5    Morley, G.E.6
  • 7
    • 36048967173 scopus 로고    scopus 로고
    • Gap junction channels and cardiac impulse propagation
    • 10.1007/s00232-007-9046-8 17661127 10.1007/s00232-007-9046-8 1:CAS:528:DC%2BD2sXht12ktL%2FF
    • Desplantez T, Dupont E, Severs NJ, Weingart R (2007) Gap junction channels and cardiac impulse propagation. J Membr Biol 218:13-28. doi: 10.1007/s00232-007-9046-8
    • (2007) J Membr Biol , vol.218 , pp. 13-28
    • Desplantez, T.1    Dupont, E.2    Severs, N.J.3    Weingart, R.4
  • 8
    • 0347635339 scopus 로고    scopus 로고
    • Functional role of connexin 43 gap junction channels in adult mouse heart assessed by inducible gene deletion
    • 10.1016/j.yjmcc.2003.10.006 14734052 10.1016/j.yjmcc.2003.10.006 1:CAS:528:DC%2BD2cXkvFOksg%3D%3D
    • Eckardt D, Theis M, Degen J, Ott T, van Rijen HV, Kirchhoff S, Kim JS, de Bakker JM, Willecke K (2004) Functional role of connexin 43 gap junction channels in adult mouse heart assessed by inducible gene deletion. J Mol Cell Cardiol 36:101-110. doi: 10.1016/j.yjmcc.2003.10.006
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 101-110
    • Eckardt, D.1    Theis, M.2    Degen, J.3    Ott, T.4    Van Rijen, H.V.5    Kirchhoff, S.6    Kim, J.S.7    De Bakker, J.M.8    Willecke, K.9
  • 9
    • 77953123127 scopus 로고    scopus 로고
    • Kinases and phosphatases in ischaemic preconditioning: A re-evaluation
    • 10.1007/s00395-010-0086-3 20127248 10.1007/s00395-010-0086-3 1:CAS:528:DC%2BC3cXlsFGrs74%3D
    • Fan WJ, van Vuuren D, Genade S, Lochner A (2010) Kinases and phosphatases in ischaemic preconditioning: a re-evaluation. Basic Res Cardiol 105:495-511. doi: 10.1007/s00395-010-0086-3
    • (2010) Basic Res Cardiol , vol.105 , pp. 495-511
    • Fan, W.J.1    Van Vuuren, D.2    Genade, S.3    Lochner, A.4
  • 10
    • 0030780568 scopus 로고    scopus 로고
    • Gap junction uncoupler heptanol prevents cell-to-cell progression of hypercontracture and limits necrosis during myocardial reperfusion
    • 10.1161/01.CIR.96.10.3579 9396458 10.1161/01.CIR.96.10.3579 1:CAS:528:DyaK2sXnslyit7g%3D
    • Garcia-Dorado D, Inserte J, Ruiz-Meana M, Gonzalez MA, Solares J, Julia M, Barrabes JA, Soler-Soler J (1997) Gap junction uncoupler heptanol prevents cell-to-cell progression of hypercontracture and limits necrosis during myocardial reperfusion. Circulation 96:3579-3586. doi: 10.1161/01.CIR.96.10.3579
    • (1997) Circulation , vol.96 , pp. 3579-3586
    • Garcia-Dorado, D.1    Inserte, J.2    Ruiz-Meana, M.3    Gonzalez, M.A.4    Solares, J.5    Julia, M.6    Barrabes, J.A.7    Soler-Soler, J.8
  • 11
    • 1142297603 scopus 로고    scopus 로고
    • Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion
    • 10.1016/j.cardiores.2003.11.039 14962471 10.1016/j.cardiores.2003.11.039 1:CAS:528:DC%2BD2cXhtFWms7g%3D
    • Garcia-Dorado D, Rodriguez-Sinovas A, Ruiz-Meana M (2004) Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion. Cardiovasc Res 61:386-401. doi: 10.1016/j.cardiores.2003. 11.039
    • (2004) Cardiovasc Res , vol.61 , pp. 386-401
    • Garcia-Dorado, D.1    Rodriguez-Sinovas, A.2    Ruiz-Meana, M.3
  • 12
    • 33746463210 scopus 로고    scopus 로고
    • Treatment with the gap junction modifier rotigaptide (ZP123) reduces infarct size in rats with chronic myocardial infarction
    • 10.1097/01.fjc.0000200990.31611.6e 16495761 10.1097/01.fjc.0000200990. 31611.6e 1:CAS:528:DC%2BD28Xhs12ns70%3D
    • Haugan K, Marcussen N, Kjolbye AL, Nielsen MS, Hennan JK, Petersen JS (2006) Treatment with the gap junction modifier rotigaptide (ZP123) reduces infarct size in rats with chronic myocardial infarction. J Cardiovasc Pharmacol 47:236-242. doi: 10.1097/01.fjc.0000200990.31611.6e
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 236-242
    • Haugan, K.1    Marcussen, N.2    Kjolbye, A.L.3    Nielsen, M.S.4    Hennan, J.K.5    Petersen, J.S.6
  • 13
    • 12344311866 scopus 로고    scopus 로고
    • Ischemic preconditioning protects by activating prosurvival kinases at reperfusion
    • 10.1152/ajpheart.00374.2004 15358610 10.1152/ajpheart.00374.2004 1:CAS:528:DC%2BD2MXhsFels7o%3D
    • Hausenloy DJ, Tsang A, Mocanu MM, Yellon DM (2005) Ischemic preconditioning protects by activating prosurvival kinases at reperfusion. Am J Physiol Heart Circ Physiol 288:H971-H976. doi: 10.1152/ajpheart.00374.2004
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Hausenloy, D.J.1    Tsang, A.2    Mocanu, M.M.3    Yellon, D.M.4
  • 14
    • 84865568181 scopus 로고    scopus 로고
    • Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction
    • 10.1016/j.yjmcc.2012.07.008 22841862 10.1016/j.yjmcc.2012.07.008 1:CAS:528:DC%2BC38XhtFGisbbI
    • Hawat G, Helie P, Baroudi G (2012) Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction. J Mol Cell Cardiol 53:559-566. doi: 10.1016/j.yjmcc.2012. 07.008
    • (2012) J Mol Cell Cardiol , vol.53 , pp. 559-566
    • Hawat, G.1    Helie, P.2    Baroudi, G.3
  • 15
    • 25444512382 scopus 로고    scopus 로고
    • Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice
    • 10.1161/01.RES.0000181171.65293.65 16100048 10.1161/01.RES.0000181171. 65293.65 1:CAS:528:DC%2BD2MXpvFGrt7s%3D
    • Heinzel FR, Luo Y, Li X, Boengler K, Buechert A, Garcia-Dorado D, Di Lisa F, Schulz R, Heusch G (2005) Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice. Circ Res 97:583-586. doi: 10.1161/01.RES.0000181171.65293.65
    • (2005) Circ Res , vol.97 , pp. 583-586
    • Heinzel, F.R.1    Luo, Y.2    Li, X.3    Boengler, K.4    Buechert, A.5    Garcia-Dorado, D.6    Di Lisa, F.7    Schulz, R.8    Heusch, G.9
  • 16
    • 69949171674 scopus 로고    scopus 로고
    • GAP-134 ([2S,4R]-1-[2-aminoacetyl]4-benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs
    • 10.1177/1074248409340779 19721133 10.1177/1074248409340779 1:CAS:528:DC%2BD1MXhtFGgs7jJ
    • Hennan JK, Swillo RE, Morgan GA, Rossman EI, Kantrowitz J, Butera J, Petersen JS, Gardell SJ, Vlasuk GP (2009) GAP-134 ([2S,4R]-1-[2-aminoacetyl]4- benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs. J Cardiovasc Pharmacol Ther 14:207-214. doi: 10.1177/1074248409340779
    • (2009) J Cardiovasc Pharmacol Ther , vol.14 , pp. 207-214
    • Hennan, J.K.1    Swillo, R.E.2    Morgan, G.A.3    Rossman, E.I.4    Kantrowitz, J.5    Butera, J.6    Petersen, J.S.7    Gardell, S.J.8    Vlasuk, G.P.9
  • 17
    • 57149142506 scopus 로고    scopus 로고
    • Cardioprotection: Nitric oxide, protein kinases, and mitochondria
    • 10.1161/CIRCULATIONAHA.108.805242 18981312 10.1161/CIRCULATIONAHA.108. 805242
    • Heusch G, Boengler K, Schulz R (2008) Cardioprotection: nitric oxide, protein kinases, and mitochondria. Circulation 118:1915-1919. doi: 10.1161/CIRCULATIONAHA.108.805242
    • (2008) Circulation , vol.118 , pp. 1915-1919
    • Heusch, G.1    Boengler, K.2    Schulz, R.3
  • 18
    • 77950348533 scopus 로고    scopus 로고
    • Inhibition of mitochondrial permeability transition pore opening: The Holy Grail of cardioprotection
    • 10.1007/s00395-009-0080-9 20066536 10.1007/s00395-009-0080-9
    • Heusch G, Boengler K, Schulz R (2010) Inhibition of mitochondrial permeability transition pore opening: the Holy Grail of cardioprotection. Basic Res Cardiol 105:151-154. doi: 10.1007/s00395-009-0080-9
    • (2010) Basic Res Cardiol , vol.105 , pp. 151-154
    • Heusch, G.1    Boengler, K.2    Schulz, R.3
  • 19
    • 33745242990 scopus 로고    scopus 로고
    • No loss of cardioprotection by postconditioning in connexin 43-deficient mice
    • 10.1007/s00395-006-0589-0 16568250 10.1007/s00395-006-0589-0 1:CAS:528:DC%2BD28Xos1ylurc%3D
    • Heusch G, Buchert A, Feldhaus S, Schulz R (2006) No loss of cardioprotection by postconditioning in connexin 43-deficient mice. Basic Res Cardiol 101:354-356. doi: 10.1007/s00395-006-0589-0
    • (2006) Basic Res Cardiol , vol.101 , pp. 354-356
    • Heusch, G.1    Buchert, A.2    Feldhaus, S.3    Schulz, R.4
  • 20
    • 81355146580 scopus 로고    scopus 로고
    • Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion
    • 10.1161/CIRCRESAHA.111.255604 21980124 10.1161/CIRCRESAHA.111.255604 1:CAS:528:DC%2BC3MXhsVCjsrnP
    • Heusch G, Musiolik J, Gedik N, Skyschally A (2011) Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion. Circ Res 109:1302-1308. doi: 10.1161/CIRCRESAHA.111.255604
    • (2011) Circ Res , vol.109 , pp. 1302-1308
    • Heusch, G.1    Musiolik, J.2    Gedik, N.3    Skyschally, A.4
  • 22
    • 0037454041 scopus 로고    scopus 로고
    • Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice
    • 10.1016/S0735-1097(02)02893-0 12598083 10.1016/S0735-1097(02)02893-0 1:CAS:528:DC%2BD3sXitVKisLg%3D
    • Kanno S, Kovacs A, Yamada KA, Saffitz JE (2003) Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice. J Am Coll Cardiol 41:681-686. doi: 10.1016/S0735-1097(02)02893-0
    • (2003) J Am Coll Cardiol , vol.41 , pp. 681-686
    • Kanno, S.1    Kovacs, A.2    Yamada, K.A.3    Saffitz, J.E.4
  • 23
    • 0347635344 scopus 로고    scopus 로고
    • Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions
    • 10.1016/j.yjmcc.2003.10.019 14734058 10.1016/j.yjmcc.2003.10.019 1:CAS:528:DC%2BD2cXkvFOktA%3D%3D
    • Li X, Heinzel FR, Boengler K, Schulz R, Heusch G (2004) Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions. J Mol Cell Cardiol 36:161-163. doi: 10.1016/j.yjmcc.2003. 10.019
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 161-163
    • Li, X.1    Heinzel, F.R.2    Boengler, K.3    Schulz, R.4    Heusch, G.5
  • 24
    • 74049159056 scopus 로고    scopus 로고
    • Amino acid transamination is crucial for ischaemic cardioprotection in normal and preconditioned isolated rat hearts-focus on l-glutamate
    • 10.1113/expphysiol.2009.049452 19717487 10.1113/expphysiol.2009.049452 1:CAS:528:DC%2BC3cXislWhs74%3D
    • Lofgren B, Povlsen JA, Rasmussen LE, Stottrup NB, Solskov L, Krarup PM, Kristiansen SB, Botker HE, Nielsen TT (2010) Amino acid transamination is crucial for ischaemic cardioprotection in normal and preconditioned isolated rat hearts-focus on l-glutamate. Exp Physiol 95:140-152. doi: 10.1113/expphysiol. 2009.049452
    • (2010) Exp Physiol , vol.95 , pp. 140-152
    • Lofgren, B.1    Povlsen, J.A.2    Rasmussen, L.E.3    Stottrup, N.B.4    Solskov, L.5    Krarup, P.M.6    Kristiansen, S.B.7    Botker, H.E.8    Nielsen, T.T.9
  • 26
    • 0036623989 scopus 로고    scopus 로고
    • PI3 kinase and not p42/p44 appears to be implicated in the protection conferred by ischemic preconditioning
    • 10.1006/jmcc.2002.2006 12054853 10.1006/jmcc.2002.2006 1:CAS:528:DC%2BD38XktlGqtb0%3D
    • Mocanu MM, Bell RM, Yellon DM (2002) PI3 kinase and not p42/p44 appears to be implicated in the protection conferred by ischemic preconditioning. J Mol Cell Cardiol 34:661-668. doi: 10.1006/jmcc.2002.2006
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 661-668
    • Mocanu, M.M.1    Bell, R.M.2    Yellon, D.M.3
  • 27
    • 42049108814 scopus 로고    scopus 로고
    • Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury
    • 10.1152/physrev.00024.2007 18391174 10.1152/physrev.00024.2007 1:CAS:528:DC%2BD1cXls1KhsL8%3D
    • Murphy E, Steenbergen C (2008) Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol Rev 88:581-609. doi: 10.1152/physrev.00024.2007
    • (2008) Physiol Rev , vol.88 , pp. 581-609
    • Murphy, E.1    Steenbergen, C.2
  • 28
    • 33746207800 scopus 로고    scopus 로고
    • Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection
    • 10.1161/01.RES.0000230315.56904.de 16741159 10.1161/01.RES.0000230315. 56904.de 1:CAS:528:DC%2BD28XmtFKntr4%3D
    • Rodriguez-Sinovas A, Boengler K, Cabestrero A, Gres P, Morente M, Ruiz-Meana M, Konietzka I, Miro E, Totzeck A, Heusch G, Schulz R, Garcia-Dorado D (2006) Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection. Circ Res 99:93-101. doi: 10.1161/01.RES. 0000230315.56904.de
    • (2006) Circ Res , vol.99 , pp. 93-101
    • Rodriguez-Sinovas, A.1    Boengler, K.2    Cabestrero, A.3    Gres, P.4    Morente, M.5    Ruiz-Meana, M.6    Konietzka, I.7    Miro, E.8    Totzeck, A.9    Heusch, G.10    Schulz, R.11    Garcia-Dorado, D.12
  • 29
    • 4444254148 scopus 로고    scopus 로고
    • Enhanced effect of gap junction uncouplers on macroscopic electrical properties of reperfused myocardium
    • 10.1113/jphysiol.2004.065144 15218064 10.1113/jphysiol.2004.065144 1:CAS:528:DC%2BD2cXntlCltbo%3D
    • Rodriguez-Sinovas A, Garcia-Dorado D, Ruiz-Meana M, Soler-Soler J (2004) Enhanced effect of gap junction uncouplers on macroscopic electrical properties of reperfused myocardium. J Physiol 559:245-257. doi: 10.1113/jphysiol.2004. 065144
    • (2004) J Physiol , vol.559 , pp. 245-257
    • Rodriguez-Sinovas, A.1    Garcia-Dorado, D.2    Ruiz-Meana, M.3    Soler-Soler, J.4
  • 31
    • 0033529651 scopus 로고    scopus 로고
    • Propagation of cardiomyocyte hypercontracture by passage of Na(+) through gap junctions
    • 10.1161/01.RES.85.3.280 10436171 10.1161/01.RES.85.3.280 1:CAS:528:DyaK1MXltFGgsLs%3D
    • Ruiz-Meana M, Garcia-Dorado D, Hofstaetter B, Piper HM, Soler-Soler J (1999) Propagation of cardiomyocyte hypercontracture by passage of Na(+) through gap junctions. Circ Res 85:280-287. doi: 10.1161/01.RES.85.3.280
    • (1999) Circ Res , vol.85 , pp. 280-287
    • Ruiz-Meana, M.1    Garcia-Dorado, D.2    Hofstaetter, B.3    Piper, H.M.4    Soler-Soler, J.5
  • 32
    • 85027929423 scopus 로고    scopus 로고
    • The role of mitochondrial permeability transition in reperfusion-induced cardiomyocyte death depends on the duration of ischemia
    • 10.1007/s00395-011-0225-5 21959501 10.1007/s00395-011-0225-5 1:CAS:528:DC%2BC3MXhsFOnsL%2FI
    • Ruiz-Meana M, Inserte J, Fernandez-Sanz C, Hernando V, Miro-Casas E, Barba I, Garcia-Dorado D (2011) The role of mitochondrial permeability transition in reperfusion-induced cardiomyocyte death depends on the duration of ischemia. Basic Res Cardiol 106:1259-1268. doi: 10.1007/s00395-011-0225-5
    • (2011) Basic Res Cardiol , vol.106 , pp. 1259-1268
    • Ruiz-Meana, M.1    Inserte, J.2    Fernandez-Sanz, C.3    Hernando, V.4    Miro-Casas, E.5    Barba, I.6    Garcia-Dorado, D.7
  • 33
    • 82855169269 scopus 로고    scopus 로고
    • Effects of a reduction in the number of gap junction channels or in their conductance on ischemia-reperfusion arrhythmias in isolated mouse hearts
    • 10.1152/ajpheart.00540.2011 21949115 10.1152/ajpheart.00540.2011 1:CAS:528:DC%2BC38XhtFWltw%3D%3D
    • Sanchez JA, Rodriguez-Sinovas A, Fernandez-Sanz C, Ruiz-Meana M, Garcia-Dorado D (2011) Effects of a reduction in the number of gap junction channels or in their conductance on ischemia-reperfusion arrhythmias in isolated mouse hearts. Am J Physiol Heart Circ Physiol 301:H2442-H2453. doi: 10.1152/ajpheart.00540.2011
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • Sanchez, J.A.1    Rodriguez-Sinovas, A.2    Fernandez-Sanz, C.3    Ruiz-Meana, M.4    Garcia-Dorado, D.5
  • 34
    • 0036783622 scopus 로고    scopus 로고
    • No ischemic preconditioning in heterozygous connexin 43-deficient mice
    • 10.1152/ajpheart.00442.2002 12234831 1:CAS:528:DC%2BD38XotVKiurs%3D
    • Schwanke U, Konietzka I, Duschin A, Li X, Schulz R, Heusch G (2002) No ischemic preconditioning in heterozygous connexin 43-deficient mice. Am J Physiol Heart Circ Physiol 283:H1740-H1742. doi: 10.1152/ajpheart.00442.2002
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Schwanke, U.1    Konietzka, I.2    Duschin, A.3    Li, X.4    Schulz, R.5    Heusch, G.6
  • 35
    • 64549084087 scopus 로고    scopus 로고
    • Reversible blockade of electron transport with amobarbital at the onset of reperfusion attenuates cardiac injury
    • 10.1016/j.trsl.2009.02.003 19375683 10.1016/j.trsl.2009.02.003 1:CAS:528:DC%2BD1MXkslyrsrY%3D
    • Stewart S, Lesnefsky EJ, Chen Q (2009) Reversible blockade of electron transport with amobarbital at the onset of reperfusion attenuates cardiac injury. Transl Res 153:224-231. doi: 10.1016/j.trsl.2009.02.003
    • (2009) Transl Res , vol.153 , pp. 224-231
    • Stewart, S.1    Lesnefsky, E.J.2    Chen, Q.3
  • 36
    • 4043060632 scopus 로고    scopus 로고
    • Postconditioning: A form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway
    • 10.1161/01.RES.0000138303.76488.fe 15242972 10.1161/01.RES.0000138303. 76488.fe 1:CAS:528:DC%2BD2cXmtVaksr0%3D
    • Tsang A, Hausenloy DJ, Mocanu MM, Yellon DM (2004) Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway. Circ Res 95:230-232. doi: 10.1161/01.RES.0000138303.76488.fe
    • (2004) Circ Res , vol.95 , pp. 230-232
    • Tsang, A.1    Hausenloy, D.J.2    Mocanu, M.M.3    Yellon, D.M.4
  • 38
    • 3242690160 scopus 로고    scopus 로고
    • Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways
    • 10.1016/j.jacc.2004.05.060 15337225 10.1016/j.jacc.2004.05.060
    • Yang XM, Proctor JB, Cui L, Krieg T, Downey JM, Cohen MV (2004) Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol 44:1103-1110. doi: 10.1016/j.jacc.2004.05.060
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1103-1110
    • Yang, X.M.1    Proctor, J.B.2    Cui, L.3    Krieg, T.4    Downey, J.M.5    Cohen, M.V.6
  • 39
    • 0033771821 scopus 로고    scopus 로고
    • Cell-to-cell interaction prevents cell death in cultured neonatal rat ventricular myocytes
    • 10.1016/S0008-6363(00)00145-0 11033109 10.1016/S0008-6363(00)00145-0 1:CAS:528:DC%2BD3cXnt1SjtLo%3D
    • Yasui K, Kada K, Hojo M, Lee JK, Kamiya K, Toyama J, Opthof T, Kodama I (2000) Cell-to-cell interaction prevents cell death in cultured neonatal rat ventricular myocytes. Cardiovasc Res 48:68-76. doi: 10.1016/S0008-6363(00)00145- 0
    • (2000) Cardiovasc Res , vol.48 , pp. 68-76
    • Yasui, K.1    Kada, K.2    Hojo, M.3    Lee, J.K.4    Kamiya, K.5    Toyama, J.6    Opthof, T.7    Kodama, I.8
  • 40
    • 84855420336 scopus 로고    scopus 로고
    • Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury
    • 10.1172/JCI44927 22201682 10.1172/JCI44927 1:CAS:528: DC%2BC38XkvFCktg%3D%3D
    • Yoshioka J, Chutkow WA, Lee S, Kim JB, Yan J, Tian R, Lindsey ML, Feener EP, Seidman CE, Seidman JG, Lee RT (2012) Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury. J Clin Invest 122:267-279. doi: 10.1172/JCI44927
    • (2012) J Clin Invest , vol.122 , pp. 267-279
    • Yoshioka, J.1    Chutkow, W.A.2    Lee, S.3    Kim, J.B.4    Yan, J.5    Tian, R.6    Lindsey, M.L.7    Feener, E.P.8    Seidman, C.E.9    Seidman, J.G.10    Lee, R.T.11


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