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Volumn 110, Issue 15, 2013, Pages 5993-5998

Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the Checkpoint kinase CHK1

Author keywords

[No Author keywords available]

Indexed keywords

B CELL TRANSLOCATION GENE 3; CHECKPOINT KINASE 1; CULLIN RING LIGASE; LYSINE; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 84876063227     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1220635110     Document Type: Article
Times cited : (31)

References (35)
  • 1
    • 73949116438 scopus 로고    scopus 로고
    • The mammalian anti-proliferative BTG/Tob protein family
    • Winkler GS (2010) The mammalian anti-proliferative BTG/Tob protein family. J Cell Physiol 222(1):66-72.
    • (2010) J Cell Physiol , vol.222 , Issue.1 , pp. 66-72
    • Winkler, G.S.1
  • 2
    • 0242446173 scopus 로고    scopus 로고
    • Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle
    • Guéhenneux F, et al. (1997) Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle. Leukemia 11(3):370-375.
    • (1997) Leukemia , vol.11 , Issue.3 , pp. 370-375
    • Guéhenneux, F.1
  • 3
    • 34548427509 scopus 로고    scopus 로고
    • The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1
    • Ou Y-H, et al. (2007) The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1. EMBO J 26(17):3968-3980.
    • (2007) EMBO J , vol.26 , Issue.17 , pp. 3968-3980
    • Ou, Y.-H.1
  • 4
    • 58549084814 scopus 로고    scopus 로고
    • Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma
    • Yoneda M, et al. (2009) Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma. Cancer Sci 100(2):225-232.
    • (2009) Cancer Sci , vol.100 , Issue.2 , pp. 225-232
    • Yoneda, M.1
  • 5
    • 64349112758 scopus 로고    scopus 로고
    • BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer
    • Majid S, et al. (2009) BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer. Carcinogenesis 30(4):662-670.
    • (2009) Carcinogenesis , vol.30 , Issue.4 , pp. 662-670
    • Majid, S.1
  • 6
    • 74549216395 scopus 로고    scopus 로고
    • Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer
    • Majid S, et al. (2010) Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer. Cancer 116(1):66-76.
    • (2010) Cancer , vol.116 , Issue.1 , pp. 66-76
    • Majid, S.1
  • 7
    • 46949097704 scopus 로고    scopus 로고
    • Methylation-mediated downregulation of the B-cell translocation gene 3 (BTG3) in breast cancer cells
    • Yu J, et al. (2008) Methylation-mediated downregulation of the B-cell translocation gene 3(BTG3) in breast cancer cells. Gene Expr 14 (3):173-182.
    • (2008) Gene Expr , vol.14 , Issue.3 , pp. 173-182
    • Yu, J.1
  • 8
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • Ciccia A, Elledge SJ (2010) The DNA damage response: Making it safe to play with knives. Mol Cell 40(2):179-204.
    • (2010) Mol Cell , vol.40 , Issue.2 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 9
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 15(17):2177-2196.
    • (2001) Genes Dev , vol.15 , Issue.17 , pp. 2177-2196
    • Abraham, R.T.1
  • 10
    • 33646777679 scopus 로고    scopus 로고
    • Rapid activation of ATR by ionizing radiation requires ATM and Mre11
    • Myers JS, Cortez D (2006) Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J Biol Chem 281(14):9346-9350.
    • (2006) J Biol Chem , vol.281 , Issue.14 , pp. 9346-9350
    • Myers, J.S.1    Cortez, D.2
  • 11
    • 0034967556 scopus 로고    scopus 로고
    • ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
    • Zhao H, Piwnica-Worms H (2001) ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 21(13):4129-4139.
    • (2001) Mol Cell Biol , vol.21 , Issue.13 , pp. 4129-4139
    • Zhao, H.1    Piwnica-Worms, H.2
  • 12
    • 4444298849 scopus 로고    scopus 로고
    • DNA damage checkpoint maintenance through sustained Chk1 activity
    • Latif C, den Elzen NR, O'Connell MJ (2004) DNA damage checkpoint maintenance through sustained Chk1 activity. J Cell Sci 117(Pt 16):3489-3498.
    • (2004) J Cell Sci , vol.117 , Issue.PART 16 , pp. 3489-3498
    • Latif, C.1    Den Elzen, N.R.2    O'Connell, M.J.3
  • 13
    • 77956472414 scopus 로고    scopus 로고
    • Chk1 suppressed cell death
    • Meuth M (2010) Chk1 suppressed cell death. Cell Div 5:21.
    • (2010) Cell Div , vol.5 , pp. 21
    • Meuth, M.1
  • 14
    • 30044440857 scopus 로고    scopus 로고
    • Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress
    • Rodriguez R, Meuth M (2006) Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress. Mol Biol Cell 17(1):402-412.
    • (2006) Mol Biol Cell , vol.17 , Issue.1 , pp. 402-412
    • Rodriguez, R.1    Meuth, M.2
  • 15
    • 70349329673 scopus 로고    scopus 로고
    • U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint
    • Carrassa L, Sanchez Y, Erba E, Damia G (2009) U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint. J Cell Mol Med 13(8 A):1565-1576.
    • (2009) J Cell Mol Med , vol.13 , Issue.8 A , pp. 1565-1576
    • Carrassa, L.1    Sanchez, Y.2    Erba, E.3    Damia, G.4
  • 16
    • 33846636785 scopus 로고    scopus 로고
    • Chk1 is required for spindle checkpoint function
    • Zachos G, et al. (2007) Chk1 is required for spindle checkpoint function. Dev Cell 12(2):247-260.
    • (2007) Dev Cell , vol.12 , Issue.2 , pp. 247-260
    • Zachos, G.1
  • 17
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan MB, Bartek J (2004) Cell-cycle checkpoints and cancer. Nature 432(7015):316-323.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 18
    • 33749998118 scopus 로고    scopus 로고
    • Mutation analysis and characterization of ATR sequence variants in breast cancer cases from high-risk French Canadian breast/ovarian cancer families
    • Durocher F, et al. (2006) Mutation analysis and characterization of ATR sequence variants in breast cancer cases from high-risk French Canadian breast/ovarian cancer families. BMC Cancer 6:230.
    • (2006) BMC Cancer , vol.6 , pp. 230
    • Durocher, F.1
  • 20
    • 0032859695 scopus 로고    scopus 로고
    • CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
    • Bertoni F, et al. (1999) CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers. Genes Chromosomes Cancer 26(2):176-180.
    • (1999) Genes Chromosomes Cancer , vol.26 , Issue.2 , pp. 176-180
    • Bertoni, F.1
  • 21
    • 13844251972 scopus 로고    scopus 로고
    • Lack of PTEN sequesters CHK1 and initiates genetic instability
    • Puc J, et al. (2005) Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell 7(2):193-204.
    • (2005) Cancer Cell , vol.7 , Issue.2 , pp. 193-204
    • Puc, J.1
  • 22
    • 25444480531 scopus 로고    scopus 로고
    • PTEN loss inhibits CHK1 to cause double stranded-DNA breaks in cells
    • Puc J, Parsons R (2005) PTEN loss inhibits CHK1 to cause double stranded-DNA breaks in cells. Cell Cycle 4(7):927-929.
    • (2005) Cell Cycle , vol.4 , Issue.7 , pp. 927-929
    • Puc, J.1    Parsons, R.2
  • 23
    • 24044476837 scopus 로고    scopus 로고
    • Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway
    • Zhang YW, et al. (2005) Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol Cell 19(5):607-618.
    • (2005) Mol Cell , vol.19 , Issue.5 , pp. 607-618
    • Zhang, Y.W.1
  • 24
    • 68949221708 scopus 로고    scopus 로고
    • The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress
    • Zhang YW, et al. (2009) The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Mol Cell 35(4):442-453.
    • (2009) Mol Cell , vol.35 , Issue.4 , pp. 442-453
    • Zhang, Y.W.1
  • 25
    • 65549090186 scopus 로고    scopus 로고
    • DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress
    • Leung-Pineda V, Huh J, Piwnica-Worms H (2009) DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress. Cancer Res 69(6):2630-2637.
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2630-2637
    • Leung-Pineda, V.1    Huh, J.2    Piwnica-Worms, H.3
  • 26
    • 33847727050 scopus 로고    scopus 로고
    • Ubiquitin proteasome system (UPS): What can chromatin do for you?
    • O'Connell BC, Harper JW (2007) Ubiquitin proteasome system (UPS): What can chromatin do for you? Curr Opin Cell Biol 19(2):206-214.
    • (2007) Curr Opin Cell Biol , vol.19 , Issue.2 , pp. 206-214
    • O'Connell, B.C.1    Harper, J.W.2
  • 27
    • 59649086030 scopus 로고    scopus 로고
    • Nonproteolytic functions of ubiquitin in cell signaling
    • Chen ZJ, Sun LJ (2009) Nonproteolytic functions of ubiquitin in cell signaling. Mol Cell 33(3):275-286.
    • (2009) Mol Cell , vol.33 , Issue.3 , pp. 275-286
    • Chen, Z.J.1    Sun, L.J.2
  • 28
    • 14044252680 scopus 로고    scopus 로고
    • Interaction of 14-3-3 protein with Chk1 affects localization and checkpoint function
    • Dunaway S, Liu H-Y, Walworth NC (2005) Interaction of 14-3-3 protein with Chk1 affects localization and checkpoint function. J Cell Sci 118(Pt 1):39-50.
    • (2005) J Cell Sci , vol.118 , Issue.PART 1 , pp. 39-50
    • Dunaway, S.1    Liu, H.-Y.2    Walworth, N.C.3
  • 29
    • 65249182632 scopus 로고    scopus 로고
    • The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis
    • Peddibhotla S, Lam MH, Gonzalez-Rimbau M, Rosen JM (2009) The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis. Proc Natl Acad Sci USA 106(13):5159-5164.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.13 , pp. 5159-5164
    • Peddibhotla, S.1    Lam, M.H.2    Gonzalez-Rimbau, M.3    Rosen, J.M.4
  • 30
    • 33747083495 scopus 로고    scopus 로고
    • Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1)
    • Tang J, Erikson RL, Liu X (2006) Checkpoint kinase 1(Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1). Proc Natl Acad Sci USA 103 (32):11964-11969.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.32 , pp. 11964-11969
    • Tang, J.1    Erikson, R.L.2    Liu, X.3
  • 31
    • 84864111648 scopus 로고    scopus 로고
    • Coupling cellular localization and function of checkpoint kinase 1 (Chk1) in checkpoints and cell viability
    • Wang J, Han X, Feng X, Wang Z, Zhang Y (2012) Coupling cellular localization and function of checkpoint kinase 1(Chk1) in checkpoints and cell viability. J Biol Chem 287 (30):25501-25509.
    • (2012) J Biol Chem , vol.287 , Issue.30 , pp. 25501-25509
    • Wang, J.1    Han, X.2    Feng, X.3    Wang, Z.4    Zhang, Y.5
  • 32
    • 84859708296 scopus 로고    scopus 로고
    • P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation
    • Li P, et al. (2012) P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation. Mol Biol Cell 23(8):1582-1592.
    • (2012) Mol Biol Cell , vol.23 , Issue.8 , pp. 1582-1592
    • Li, P.1
  • 33
    • 28544453333 scopus 로고    scopus 로고
    • Chromosome alignment and segregation regulated by ubiquitination of survivin
    • Vong QP, Cao K, Li HY, Iglesias PA, Zheng Y (2005) Chromosome alignment and segregation regulated by ubiquitination of survivin. Science 310(5753):1499-1504.
    • (2005) Science , vol.310 , Issue.5753 , pp. 1499-1504
    • Vong, Q.P.1    Cao, K.2    Li, H.Y.3    Iglesias, P.A.4    Zheng, Y.5
  • 34
    • 0034677597 scopus 로고    scopus 로고
    • The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: Implications for Chk1 regulation
    • Chen P, et al. (2000) The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: Implications for Chk1 regulation. Cell 100(6):681-692.
    • (2000) Cell , vol.100 , Issue.6 , pp. 681-692
    • Chen, P.1
  • 35
    • 80054762706 scopus 로고    scopus 로고
    • Aneuploidy and tumorigenesis
    • Fang X, Zhang P (2011) Aneuploidy and tumorigenesis. Semin Cell Dev Biol 22(6):595-601.
    • (2011) Semin Cell Dev Biol , vol.22 , Issue.6 , pp. 595-601
    • Fang, X.1    Zhang, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.