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Volumn 8, Issue 4, 2013, Pages

Epitope-Based Vaccines with the Anaplasma marginale MSP1a Functional Motif Induce a Balanced Humoral and Cellular Immune Response in Mice

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; BACTERIAL VACCINE; BOVINE SERUM ALBUMIN; EPITOPE; FREUND ADJUVANT; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; MAJOR SURFACE PROTEIN 1; SERYLGLUTAMYLALANYLSERYLTHREONYLSERYLSERYLGLUTAMINYLLEUCYLGLYCYLALANYLGLYCYLGLYCYLGLYCYLSERYLSERYLGLUTAMYLALANYLSERYLTHREONYLSERYLSERYLGLUTAMINYLLEUCYLGLYCYLALANINE; SERYLTHREONYLSERYLSERYLGLUTAMINYLLEUCYLGLYCYLGLYCYLGLYCYLSERYLSERYLTHREONYLSERYLSERYLGLUTAMINYLLEUCYLGLYCYLGLYCYLGLYCYLSERYLSERYLTHREONYLSERYLSERYLGLUTAMINYLLEUCINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

EID: 84876006528     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060311     Document Type: Article
Times cited : (17)

References (51)
  • 3
    • 0032968048 scopus 로고    scopus 로고
    • Biased immunoglobulin G1 isotype responses induced in cattle with DNA expressing msp1a of Anaplasma marginale
    • Arulkanthan A, Brown WC, McGuire TC, Knowles DP, (1999) Biased immunoglobulin G1 isotype responses induced in cattle with DNA expressing msp1a of Anaplasma marginale. Infect Immun 67: 3481-3487.
    • (1999) Infect Immun , vol.67 , pp. 3481-3487
    • Arulkanthan, A.1    Brown, W.C.2    McGuire, T.C.3    Knowles, D.P.4
  • 4
    • 10444257303 scopus 로고    scopus 로고
    • Immunization of bovines using a DNA vaccine (pcDNA3.1/MSP1b) prepared from the Jaboticabal strain of Anaplasma marginale
    • de Andrade GM, Machado RZ, Vidotto MC, Vidotto O, (2004) Immunization of bovines using a DNA vaccine (pcDNA3.1/MSP1b) prepared from the Jaboticabal strain of Anaplasma marginale. Ann N Y Acad Sci 1026: 257-266.
    • (2004) Ann N Y Acad Sci , vol.1026 , pp. 257-266
    • de Andrade, G.M.1    Machado, R.Z.2    Vidotto, M.C.3    Vidotto, O.4
  • 5
    • 34548577406 scopus 로고    scopus 로고
    • Immune response of BALB/c mouse immunized with recombinant MSPs proteins of Anaplasma marginale binding to immunostimulant complex (ISCOM)
    • Kawasaki PM, Kano FS, Tamekuni K, Garcia JL, Marana ER, et al. (2007) Immune response of BALB/c mouse immunized with recombinant MSPs proteins of Anaplasma marginale binding to immunostimulant complex (ISCOM). Res Vet Sci 83: 347-354.
    • (2007) Res Vet Sci , vol.83 , pp. 347-354
    • Kawasaki, P.M.1    Kano, F.S.2    Tamekuni, K.3    Garcia, J.L.4    Marana, E.R.5
  • 6
    • 44749091901 scopus 로고    scopus 로고
    • Induced immune response of DNA vaccine encoding an association MSP1a, MSP1b, and MSP5 antigens of Anaplasma marginale
    • Kano FS, Tamekuni K, Coelho AL, Garcia JL, Vidotto O, et al. (2008) Induced immune response of DNA vaccine encoding an association MSP1a, MSP1b, and MSP5 antigens of Anaplasma marginale. Vaccine 26: 3522-3527.
    • (2008) Vaccine , vol.26 , pp. 3522-3527
    • Kano, F.S.1    Tamekuni, K.2    Coelho, A.L.3    Garcia, J.L.4    Vidotto, O.5
  • 7
    • 84887024017 scopus 로고    scopus 로고
    • Induced immune response of Escherichia coli BL21 expressing recombinant MSP1a and MSP1b proteins of Anaplasma marginale
    • Tamekuni K, Vidotto MC, Felix SR, Igarashi M, Garcia JL, et al. (2009) Induced immune response of Escherichia coli BL21 expressing recombinant MSP1a and MSP1b proteins of Anaplasma marginale. Braz Arch Biol Technol 52: 113-120.
    • (2009) Braz Arch Biol Technol , vol.52 , pp. 113-120
    • Tamekuni, K.1    Vidotto, M.C.2    Felix, S.R.3    Igarashi, M.4    Garcia, J.L.5
  • 8
    • 0027991698 scopus 로고
    • Putative adhesins of Anaplasma marginale: major surface polypeptides 1a and 1b
    • McGarey DJ, Barbet AF, Palmer GH, McGuire TC, Allred DR, (1994) Putative adhesins of Anaplasma marginale: major surface polypeptides 1a and 1b. Infect Immun 62: 4594-4601.
    • (1994) Infect Immun , vol.62 , pp. 4594-4601
    • McGarey, D.J.1    Barbet, A.F.2    Palmer, G.H.3    McGuire, T.C.4    Allred, D.R.5
  • 9
    • 0024450997 scopus 로고
    • Immunization of cattle with the MSP-1 surface protein complex induces protection against a structurally variant Anaplasma marginale isolate
    • Palmer GH, Barbet AF, Cantor GH, McGuire TC, (1989) Immunization of cattle with the MSP-1 surface protein complex induces protection against a structurally variant Anaplasma marginale isolate. Infect Immun 57: 3666-3669.
    • (1989) Infect Immun , vol.57 , pp. 3666-3669
    • Palmer, G.H.1    Barbet, A.F.2    Cantor, G.H.3    McGuire, T.C.4
  • 10
    • 0035114134 scopus 로고    scopus 로고
    • Differential adhesion of major surface proteins 1a and 1b of the ehrlichial cattle pathogen Anaplasma marginale to bovine erythrocytes and tick cells
    • de la Fuente J, Garcia-Garcia JC, Blouin EF, Kocan KM, (2001) Differential adhesion of major surface proteins 1a and 1b of the ehrlichial cattle pathogen Anaplasma marginale to bovine erythrocytes and tick cells. Int J Parasitol 31: 145-153.
    • (2001) Int J Parasitol , vol.31 , pp. 145-153
    • de la Fuente, J.1    Garcia-Garcia, J.C.2    Blouin, E.F.3    Kocan, K.M.4
  • 11
    • 57749094326 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of the MSP1a and MSP1b recombinant proteins from PR1 Anaplasma marginale strain, Brazil
    • Tamekuni K, Kano FS, Ataliba AC, Marana ER, Venancio EJ, et al. (2009) Cloning, expression, and characterization of the MSP1a and MSP1b recombinant proteins from PR1 Anaplasma marginale strain, Brazil. Res Vet Sci 86: 98-107.
    • (2009) Res Vet Sci , vol.86 , pp. 98-107
    • Tamekuni, K.1    Kano, F.S.2    Ataliba, A.C.3    Marana, E.R.4    Venancio, E.J.5
  • 12
    • 0028918513 scopus 로고
    • Molecular basis for vaccine development against anaplasmosis and babesiosis
    • Palmer GH, McElwain TF, (1995) Molecular basis for vaccine development against anaplasmosis and babesiosis. Vet Parasitol 57: 233-253.
    • (1995) Vet Parasitol , vol.57 , pp. 233-253
    • Palmer, G.H.1    McElwain, T.F.2
  • 14
    • 0025800571 scopus 로고
    • Induction of protective immunity by using Anaplasma marginale initial body membranes
    • Tebele N, McGuire TC, Palmer GH, (1991) Induction of protective immunity by using Anaplasma marginale initial body membranes. Infect Immun 59: 3199-3204.
    • (1991) Infect Immun , vol.59 , pp. 3199-3204
    • Tebele, N.1    McGuire, T.C.2    Palmer, G.H.3
  • 15
    • 0034781872 scopus 로고    scopus 로고
    • CD4(+) T lymphocytes from calves immunized with Anaplasma marginale major surface protein 1 (MSP1), a heteromeric complex of MSP1a and MSP1b, preferentially recognize the MSP1a carboxyl terminus that is conserved among strains
    • Brown WC, Palmer GH, Lewin HA, McGuire TC, (2001) CD4(+) T lymphocytes from calves immunized with Anaplasma marginale major surface protein 1 (MSP1), a heteromeric complex of MSP1a and MSP1b, preferentially recognize the MSP1a carboxyl terminus that is conserved among strains. Infect Immun 69: 6853-6862.
    • (2001) Infect Immun , vol.69 , pp. 6853-6862
    • Brown, W.C.1    Palmer, G.H.2    Lewin, H.A.3    McGuire, T.C.4
  • 16
    • 0025255264 scopus 로고
    • Molecular basis for surface antigen size polymorphisms and conservation of a neutralization-sensitive epitope in Anaplasma marginale
    • Allred DR, McGuire TC, Palmer GH, Leib SR, Harkins TM, et al. (1990) Molecular basis for surface antigen size polymorphisms and conservation of a neutralization-sensitive epitope in Anaplasma marginale. Proc Natl Acad Sci U S A 87: 3220-3224.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 3220-3224
    • Allred, D.R.1    McGuire, T.C.2    Palmer, G.H.3    Leib, S.R.4    Harkins, T.M.5
  • 17
    • 0023431652 scopus 로고
    • Characterization of a neutralization-sensitive epitope on the Am 105 surface protein of Anaplasma marginale
    • Palmer GH, Waghela SD, Barbet AF, Davis WC, McGuire TC, (1987) Characterization of a neutralization-sensitive epitope on the Am 105 surface protein of Anaplasma marginale. Int J Parasitol 17: 1279-1285.
    • (1987) Int J Parasitol , vol.17 , pp. 1279-1285
    • Palmer, G.H.1    Waghela, S.D.2    Barbet, A.F.3    Davis, W.C.4    McGuire, T.C.5
  • 18
    • 0032425064 scopus 로고    scopus 로고
    • CD4(+) T-lymphocyte and immunoglobulin G2 responses in calves immunized with Anaplasma marginale outer membranes and protected against homologous challenge
    • Brown WC, Shkap V, Zhu D, McGuire TC, Tuo W, et al. (1998) CD4(+) T-lymphocyte and immunoglobulin G2 responses in calves immunized with Anaplasma marginale outer membranes and protected against homologous challenge. Infect Immun 66: 5406-5413.
    • (1998) Infect Immun , vol.66 , pp. 5406-5413
    • Brown, W.C.1    Shkap, V.2    Zhu, D.3    McGuire, T.C.4    Tuo, W.5
  • 19
    • 0028174222 scopus 로고
    • IFN-gamma stimulates IgG2 production from bovine B cells costimulated with anti-mu and mitogen
    • Estes DM, Closser NM, Allen GK, (1994) IFN-gamma stimulates IgG2 production from bovine B cells costimulated with anti-mu and mitogen. Cell Immunol 154: 287-295.
    • (1994) Cell Immunol , vol.154 , pp. 287-295
    • Estes, D.M.1    Closser, N.M.2    Allen, G.K.3
  • 20
    • 0041402836 scopus 로고    scopus 로고
    • Epitope-based vaccines: an update on epitope identification, vaccine design and delivery
    • Sette A, Fikes J, (2003) Epitope-based vaccines: an update on epitope identification, vaccine design and delivery. Curr Opin Immunol 15: 461-470.
    • (2003) Curr Opin Immunol , vol.15 , pp. 461-470
    • Sette, A.1    Fikes, J.2
  • 21
    • 84863268598 scopus 로고    scopus 로고
    • Functional epitope core motif of the Anaplasma marginale major surface protein 1a and its incorporation onto bioelectrodes for antibody detection
    • doi 10.1371/journal.pone.0033045
    • Santos PS, Nascimento R, Rodrigues LP, Santos FAA, Faria PCB, et al. (2012) Functional epitope core motif of the Anaplasma marginale major surface protein 1a and its incorporation onto bioelectrodes for antibody detection. PLoS One 7: e33045 doi:10.1371/journal.pone.0033045.
    • (2012) PLoS One , vol.7
    • Santos, P.S.1    Nascimento, R.2    Rodrigues, L.P.3    Santos, F.A.A.4    Faria, P.C.B.5
  • 22
    • 65649144613 scopus 로고    scopus 로고
    • Purification of nucleic acids by extraction with phenol:chloroform
    • doi:10.1101/pdb.prot4455
    • Sambrook J, Russell DW (2006) Purification of nucleic acids by extraction with phenol:chloroform. Cold Spring Harb Protoc. doi:10.1101/pdb.prot4455.
    • (2006) Cold Spring Harb Protoc
    • Sambrook, J.1    Russell, D.W.2
  • 23
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK, (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 24
    • 0021154990 scopus 로고
    • Immunoblotting and dot immunobinding-current status and outlook
    • Towbin H, Gordon J, (1984) Immunoblotting and dot immunobinding-current status and outlook. J Immunol Methods 72: 313-340.
    • (1984) J Immunol Methods , vol.72 , pp. 313-340
    • Towbin, H.1    Gordon, J.2
  • 25
    • 11144351704 scopus 로고    scopus 로고
    • Comparison of three oxytetracycline regimes for the treatment of persistent Anaplasma marginale infections in beef cattle
    • Coetzee JF, Apley MD, Kocan KM, Rurangirwa FR, Van Donkersgoed J, (2005) Comparison of three oxytetracycline regimes for the treatment of persistent Anaplasma marginale infections in beef cattle. Vet Parasitol 127: 61-73.
    • (2005) Vet Parasitol , vol.127 , pp. 61-73
    • Coetzee, J.F.1    Apley, M.D.2    Kocan, K.M.3    Rurangirwa, F.R.4    Van Donkersgoed, J.5
  • 26
    • 33846144432 scopus 로고    scopus 로고
    • Experimental infection of C3H/HeJ mice with the NY18 isolate of Anaplasma phagocytophilum
    • Blas-Machado U, de la Fuente J, Blouin EF, Almazán C, Kocan KM, et al. (2007) Experimental infection of C3H/HeJ mice with the NY18 isolate of Anaplasma phagocytophilum. Vet Pathol 44: 64-73.
    • (2007) Vet Pathol , vol.44 , pp. 64-73
    • Blas-Machado, U.1    de la Fuente, J.2    Blouin, E.F.3    Almazán, C.4    Kocan, K.M.5
  • 27
    • 26044474457 scopus 로고    scopus 로고
    • Genetic diversity of Anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development
    • de la Fuente J, Lew A, Lutz H, Meli ML, Hofmann-Lehmann R, et al. (2005) Genetic diversity of Anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development. Anim Health Res Rev 6: 75-89.
    • (2005) Anim Health Res Rev , vol.6 , pp. 75-89
    • de la Fuente, J.1    Lew, A.2    Lutz, H.3    Meli, M.L.4    Hofmann-Lehmann, R.5
  • 28
    • 0037413897 scopus 로고    scopus 로고
    • Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells
    • de la Fuente J, Garcia-Garcia JC, Blouin EF, Kocan KM, (2003) Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells. Vet Microbiol 91: 265-283.
    • (2003) Vet Microbiol , vol.91 , pp. 265-283
    • de la Fuente, J.1    Garcia-Garcia, J.C.2    Blouin, E.F.3    Kocan, K.M.4
  • 29
    • 0028100396 scopus 로고
    • Characterization of hemagglutinating components on the Anaplasma marginale initial body surface and identification of possible adhesins
    • McGarey DJ, Allred DR, (1994) Characterization of hemagglutinating components on the Anaplasma marginale initial body surface and identification of possible adhesins. Infect Immun 62: 4587-4593.
    • (1994) Infect Immun , vol.62 , pp. 4587-4593
    • McGarey, D.J.1    Allred, D.R.2
  • 30
    • 0022461701 scopus 로고
    • Immunization with an isolate-common surface protein protects cattle against anaplasmosis
    • Palmer GH, Barbet AF, Davis WC, McGuire TC, (1986) Immunization with an isolate-common surface protein protects cattle against anaplasmosis. Science 231: 1299-1302.
    • (1986) Science , vol.231 , pp. 1299-1302
    • Palmer, G.H.1    Barbet, A.F.2    Davis, W.C.3    McGuire, T.C.4
  • 31
    • 0031436967 scopus 로고    scopus 로고
    • Immunization against the agent of human granulocytic ehrlichiosis in a murine model
    • JW IJ
    • Sun W, JW IJ, Telford SR 3rd, Hodzic E, Zhang Y, et al (1997) Immunization against the agent of human granulocytic ehrlichiosis in a murine model. J Clin Invest 100: 3014-3018.
    • (1997) J Clin Invest , vol.100 , pp. 3014-3018
    • Sun, W.1    Telford 3rd, S.R.2    Hodzic, E.3    Zhang, Y.4
  • 32
    • 17444446952 scopus 로고    scopus 로고
    • A DNA vaccine encoding Cu,Zn superoxide dismutase of Brucella abortus induces protective immunity in BALB/c mice
    • Onate AA, Cespedes S, Cabrera A, Rivers R, Gonzalez A, et al. (2003) A DNA vaccine encoding Cu,Zn superoxide dismutase of Brucella abortus induces protective immunity in BALB/c mice. Infect Immun 71: 4857-4861.
    • (2003) Infect Immun , vol.71 , pp. 4857-4861
    • Onate, A.A.1    Cespedes, S.2    Cabrera, A.3    Rivers, R.4    Gonzalez, A.5
  • 33
    • 0344915162 scopus 로고    scopus 로고
    • Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response
    • Yip HC, Karulin AY, Tary-Lehmann M, Hesse MD, Radeke H, et al. (1999) Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response. J Immunol 162: 3942-3249.
    • (1999) J Immunol , vol.162 , pp. 3249-3942
    • Yip, H.C.1    Karulin, A.Y.2    Tary-Lehmann, M.3    Hesse, M.D.4    Radeke, H.5
  • 34
    • 0027323473 scopus 로고
    • Opsonization of Anaplasma marginale mediated by bovine antibody against surface protein MSP-1
    • Cantor GH, Pontzer CH, Palmer GH, (1993) Opsonization of Anaplasma marginale mediated by bovine antibody against surface protein MSP-1. Vet Immunol Immunopathol 37: 343-350.
    • (1993) Vet Immunol Immunopathol , vol.37 , pp. 343-350
    • Cantor, G.H.1    Pontzer, C.H.2    Palmer, G.H.3
  • 35
    • 0028365633 scopus 로고
    • Inducible L-arginine-dependent nitric oxide synthase activity in bovine bone marrow-derived macrophages
    • Adler H, Peterhans E, Nicolet J, Jungi TW, (1994) Inducible L-arginine-dependent nitric oxide synthase activity in bovine bone marrow-derived macrophages. Biochem Biophys Res Commun 198: 510-515.
    • (1994) Biochem Biophys Res Commun , vol.198 , pp. 510-515
    • Adler, H.1    Peterhans, E.2    Nicolet, J.3    Jungi, T.W.4
  • 36
    • 0031715666 scopus 로고    scopus 로고
    • Stimulation of nitric oxide production in macrophages by Babesia bovis
    • Stich RW, Shoda LK, Dreewes M, Adler B, Jungi TW, et al. (1998) Stimulation of nitric oxide production in macrophages by Babesia bovis. Infect Immun 66: 4130-4136.
    • (1998) Infect Immun , vol.66 , pp. 4130-4136
    • Stich, R.W.1    Shoda, L.K.2    Dreewes, M.3    Adler, B.4    Jungi, T.W.5
  • 37
    • 0034100619 scopus 로고    scopus 로고
    • Gamma interferon dominates the murine cytokine response to the agent of human granulocytic ehrlichiosis and helps to control the degree of early rickettsemia
    • Akkoyunlu M, Fikrig E, (2000) Gamma interferon dominates the murine cytokine response to the agent of human granulocytic ehrlichiosis and helps to control the degree of early rickettsemia. Infect Immun 68: 1827-1833.
    • (2000) Infect Immun , vol.68 , pp. 1827-1833
    • Akkoyunlu, M.1    Fikrig, E.2
  • 38
    • 0036844617 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of and protection against malaria
    • Angulo I, Fresno M, (2002) Cytokines in the pathogenesis of and protection against malaria. Clin Diagn Lab Immunol 9: 1145-1152.
    • (2002) Clin Diagn Lab Immunol , vol.9 , pp. 1145-1152
    • Angulo, I.1    Fresno, M.2
  • 39
    • 0035014461 scopus 로고    scopus 로고
    • Immunopathology and ehrlichial propagation are regulated by interferon-gamma and interleukin-10 in a murine model of human granulocytic ehrlichiosis
    • Martin ME, Caspersen K, Dumler JS, (2001) Immunopathology and ehrlichial propagation are regulated by interferon-gamma and interleukin-10 in a murine model of human granulocytic ehrlichiosis. Am J Pathol 158: 1881-1888.
    • (2001) Am J Pathol , vol.158 , pp. 1881-1888
    • Martin, M.E.1    Caspersen, K.2    Dumler, J.S.3
  • 40
    • 0034109478 scopus 로고    scopus 로고
    • Comparative pathology, and immunohistology associated with clinical illness after Ehrlichia phagocytophila-group infections
    • Lepidi H, Bunnell JE, Martin ME, Madigan JE, Stuen S, et al. (2000) Comparative pathology, and immunohistology associated with clinical illness after Ehrlichia phagocytophila-group infections. Am J Trop Med Hyg 62: 29-37.
    • (2000) Am J Trop Med Hyg , vol.62 , pp. 29-37
    • Lepidi, H.1    Bunnell, J.E.2    Martin, M.E.3    Madigan, J.E.4    Stuen, S.5
  • 43
    • 0036570015 scopus 로고    scopus 로고
    • The role of IL-18 in blood-stage immunity against murine malaria Plasmodium yoelii 265 and Plasmodium berghei ANKA
    • Singh RP, Kashiwamura S, Rao P, Okamura H, Mukherjee A, et al. (2002) The role of IL-18 in blood-stage immunity against murine malaria Plasmodium yoelii 265 and Plasmodium berghei ANKA. J Immunol 168: 4674-4681.
    • (2002) J Immunol , vol.168 , pp. 4674-4681
    • Singh, R.P.1    Kashiwamura, S.2    Rao, P.3    Okamura, H.4    Mukherjee, A.5
  • 44
    • 0041823567 scopus 로고    scopus 로고
    • Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies
    • Li C, Sanni LA, Omer F, Riley E, Langhorne J, (2003) Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. Infect Immun 71: 4850-4856.
    • (2003) Infect Immun , vol.71 , pp. 4850-4856
    • Li, C.1    Sanni, L.A.2    Omer, F.3    Riley, E.4    Langhorne, J.5
  • 45
    • 77950909696 scopus 로고    scopus 로고
    • Interleukin 12 a key immunoregulatory cytokine in infection applications
    • Hamza T, Barnett JB, Li B, (2010) Interleukin 12 a key immunoregulatory cytokine in infection applications. Int J Mol Sci 11: 789-806.
    • (2010) Int J Mol Sci , vol.11 , pp. 789-806
    • Hamza, T.1    Barnett, J.B.2    Li, B.3
  • 47
    • 0345447697 scopus 로고    scopus 로고
    • Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen
    • Berg RE, Crossley E, Murray S, Forman J, (2003) Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen. J Exp Med 198: 1583-1593.
    • (2003) J Exp Med , vol.198 , pp. 1583-1593
    • Berg, R.E.1    Crossley, E.2    Murray, S.3    Forman, J.4
  • 48
    • 9144235505 scopus 로고    scopus 로고
    • Activation of virus-specific CD8+ T cells by lipopolysaccharide-induced IL-12 and IL-18
    • Raue HP, Brien JD, Hammarlund E, Slifka MK, (2004) Activation of virus-specific CD8+ T cells by lipopolysaccharide-induced IL-12 and IL-18. J Immunol 173: 6873-6881.
    • (2004) J Immunol , vol.173 , pp. 6873-6881
    • Raue, H.P.1    Brien, J.D.2    Hammarlund, E.3    Slifka, M.K.4
  • 49
    • 36248968798 scopus 로고    scopus 로고
    • ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection
    • Pedra JH, Sutterwala FS, Sukumaran B, Ogura Y, Qian F, et al. (2007) ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection. J Immunol 179: 4783-4791.
    • (2007) J Immunol , vol.179 , pp. 4783-4791
    • Pedra, J.H.1    Sutterwala, F.S.2    Sukumaran, B.3    Ogura, Y.4    Qian, F.5
  • 51
    • 0027171012 scopus 로고
    • Impact of persistent Anaplasma marginale rickettsemia on tick infection and transmission
    • Eriks IS, Stiller D, Palmer GH, (1993) Impact of persistent Anaplasma marginale rickettsemia on tick infection and transmission. J Clin Microbiol 31: 2091-2096.
    • (1993) J Clin Microbiol , vol.31 , pp. 2091-2096
    • Eriks, I.S.1    Stiller, D.2    Palmer, G.H.3


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