Comparative pathology and immunohistology associated with clinical illness after Ehrlichia phagocytophila-group infections

American Journal of Tropical Medicine and Hygiene

Volumn 62, Issue 1, 2000, Pages 29-37

  Lepidi, Hubert ^a   Bunnell, Joseph E ^b   Martin, Mary E ^c   Madigan, John E ^d   Stuen, Snorre ^e   Dumler, J Stephen ^f  

^a AIX MARSEILLE UNIVERSITY   (France)

^b University of Texas Medical Branch School of Medicine   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Norwegian Coll of Vet Science   (Norway)

^f DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE;

ADULT; AGED; ANAPLASMA PHAGOCYTOPHILUM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EHRLICHIOSIS; FEMALE; FEVER; HEADACHE; HORSE; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; LEUKOPENIA; LYMPH NODE HYPERPLASIA; LYMPHOCYTE DEPLETION; MACROPHAGE; MALAISE; MALE; MYALGIA; NEUTROPHIL; NONHUMAN; SCHOOL CHILD; SHEEP; SPLEEN LYMPHOCYTE; THROMBOCYTOPENIA;

ANAPLASMA PHAGOCYTOPHILUM; ANIMALIA; EHRLICHIA; EQUIDAE; EQUUS CABALLUS; OVIS ARIES; RICKETTSIALES;

EID: 0034109478     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2000.62.29     Document Type: Article

References (39)

1. Rikihisa Y, 1991. The tribe Ehrlichieae and ehrlichial diseases. Clin Microbiol Rev 4: 286-308.
2. Foggie A, 1951. Studies on the infectious agent of tick-borne fever in sheep. J Pathol Bacteriol 63: 1-15.
3. Madigan JE, Gribble D, 1987. Equine ehrlichiosis in northern California: 49 cases (1968-1981). J Am Vet Med Assoc 190: 445-448.
4. Lewis GE, Huxsoll DL, Ristic M, Johnson AJ, 1975. Experimentally induced infection of dogs, cats, and nonhuman primates with Ehrlichia equi, etiologic agent of equine ehrlichiosis. Am J Vet Res 36: 85-88.
5. Bakken JS, Krueth J, Wilson-Nordskog C, Tilden RL, Asanovich K, Dumler JS, 1996. Clinical and laboratory characteristics of human granulocytic ehrlichiosis. JAMA 275: 199-205.
6. Chen S-M, Dumler JS, Bakken JS, Walker DH, 1994. Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J Clin Microbiol 32: 589-595.
7. Madigan JE, Barlough JE, Dumler JS, Schankman NS, DeRock E, 1996. Equine granulocytic ehrlichiosis in Connecticut caused by an agent resembling the human granulocytic ehrlichia. J Clin Microbiol 34: 434-435.
8. Sumner JW, Nicholson WL, Massung RF, 1997. PCR amplification and comparison of nucleotide sequences from the groESL heat shock operon of Ehrlichia species. J Clin Microbiol 35: 2087-2092.
9. Dumler JS, Asanovich KM, Bakken JS, Richter P, Kimsey R, Madigan JE, 1995. Serologic cross-reaction among Ehrlichia equi. Ehrlichia phagocytophila, and human granulocytic ehrlichia. J Clin Microbiol 33: 1098-1103.
10. Madigan JE, Richter PJ Jr, Kimsey RB, Barlough JE, Bakken JS, Dumler JS, 1995. Transmission and passage in horses of the agent of human granulocytic ehrlichiosis. J Infect Dis 172: 1141-1144.
11. Barlough JE, Madigan JE, DeRock E, Dumler JS, Bakken JS, 1995. Protection against Ehrlichia equi is conferred by prior infection with the human granulocytotropic ehrlichia (HGE agent). J Clin Microbiol 33: 3333-3334.
12. Gordon WS, Brownlee A, Wilson DR, MacLeod J, 1932. Tick-borne fever. J Comp Pathol Ther 45: 301-307.
13. Stuen S. Sjodogg (tick-borne fever) - a historical review (in Norwegian), 1998. Nor Vet Tidsskr 110: 703-706.
14. Woldehiwet Z, Scott GR, 1993. Tick-borne (pasture) fever. Woldehiwet Z, Ristic M, eds. Rickettsial and Chlamydial Diseases of Domestic Animals. Oxford, United Kingdom: Pergamon Press, 233-254.
15. Gribble DH, 1969. Equine ehrlichiosis. J Am Vet Med Assoc 155: 462-469.
16. Stannard AA, Gribble DH, Smith RS, 1969. Equine ehrlichiosis, a disease with similarities to tick-borne fever and bovine petechial fever. Vet Rec 84: 149-150.
17. Aguero-Rosenfeld ME, Horowitz HW, Wormser GP, McKenna DF, Nowakowski J, Mun̂oz J, Dumler JS, 1996. Human granulocytic ehrlichiosis (HGE): a series from a single medical center in New York state. Ann Intern Med 125: 904-908.
18. Pancholi P, Kolbert CP, Mitchell PD, Reed KD, Dumler JS, Bakken JS, Telford SR, Persing DH, 1995. Ixodes dammini as a potential vector of human granulocytic ehrlichiosis. J Infect Dis 172: 1007-1012.
19. Telford SR, Dawson JE, Katavolos P, Warner CK, Kolbert CP, Persing DH, 1996. Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle. Proc Natl Acad Sci USA 93: 6209-6214.
20. Walls JJ, Greig B, Neitzel DF, Dumler JS, 1997. Natural infection of small mammal species in Minnesota with the agent of human granulocytic ehrlichiosis. J Clin Microbiol 35: 853-855.
21. Belongia EA, Reed KD, Mitchell PD, Kolbert CP, Persing DH, Gill JS, Kazmierczak JJ, 1997. Prevalence of granulocytic Ehrlichia infection among white-tailed deer in Wisconsin. J Clin Microbiol 35: 1465-1468.
22. Bakken JS, Dumler JS, Chen SM, Eckman MR, Van Etta LL, Walker DH, 1994. Human granulocytic ehrlichiosis in the upper midwest United States: a new species emerging? JAMA 272: 212-218.
23. Hardalo C, Quagliarello V, Dumler JS, 1995. Human granulocytic ehrlichiosis in Connecticut: report of a fatal case. Clin Infect Dis 21: 910-914.
24. Walker DH, Dumler JS, 1997. Human monocytic and granulocytic ehrlichioses. Discovery and diagnosis of emerging tick-borne infections and the critical role of the pathologist. Arch Pathol Lab Med 121: 785-791.
25. Goodman JL, Nelson C, Vitale B, Madigan JE, Dumler JS, Kurtti TJ, Munderloh UG, 1996. Direct cultivation of the causative agent of human granulocytic ehrlichiosis. N Engl J Med 334: 209-215.
26. Jahangir A, Kolbert C, Edwards W, Mitchell P, Hall JF, Dumler JS, Persing DH, 1998. Fatal pancarditis associated with granulocytic ehrlichiosis in a 44 year-old man. Clin Infect Dis 27: 1424-1427.
27. Cartun RW, Pederson CA, 1989. An immunocytochemical technique offering increased sensitivity and a lowered cost with a streptavidin horseradish-peroxidase conjugate. J Histotech 12: 273-277.
28. Dumler JS, Bakken JS, 1995. Ehrlichial diseases of humans: emerging tick-borne infections. Clin Infect Dis 20: 1102-1110.
29. Jongejan F, Wassink LA, Thielemans MJC, Perie NM, Uilenberg G, 1989. Serotypes in Cowdria ruminantium and their relationship with Ehrlichia phagocytophila determined by immunofluorescence. Vet Microbiol 21: 31-40.
30. Weiss SJ, 1989. Tissue destruction by neutrophils. N Engl J Med 320: 365-376.
31. Smith A, 1994. Neutrophils, host defense, and inflammation: a double-edged sword. J Leukoc Biol 56: 672-686.
32. Wong SJ, Grady LJ, 1996. Ehrlichia infection as a cause of severe respiratory distress. N Engl J Med 334: 273.
33. Heimer R, van Andel A, Wormser GP, Wilson ML, 1997. Propagation of granulocytic Ehrlichia spp. from human and equine sources in HL-60 cells induced to differentiate into functional granulocytes. J Clin Microbiol 35: 923-927.
34. Klein MB, Miller JS, Nelson CM, Goodman JL, 1997. Primary bone marrow progenitors of both granulocytic and monocytic lineages are susceptible to infection with the agent of human granulocytic ehrlichiosis. J Infect Dis 176: 1405-1409.
35. Marty A, Dumler JS, Imes G, Brusman HP, Smrkovski LL, Frisman DM, 1995. Ehrlichiosis mimicking thrombotic thrombocytopenic purpura. Case report and pathological correlation. Hum Pathol 26: 920-925.
36. Cassatella MA, 1995. The production of cytokines by polymorphonuclear neutrophils. Immunol Today 16: 21-26.
37. Kasama T, Strieter RM, Stantiford TJ, Burdick MD, Kunkel SL, 1993. Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1α. J Exp Med 178: 63-72.
38. Larsen HJS, Øvernes G, Waldeland H, Johansen GM, 1994. Immunosuppression in sheep experimentally infected with Ehrlichia phagocytophila. Res Vet Sci 56: 216-224.
39. Woldehiwet Z, 1987. The effects of tick-borne fever on some functions of polymorphonuclear cells of sheep. J Comp Pathol 97: 481-485.