메뉴 건너뛰기




Volumn 190, Issue 8, 2013, Pages 4205-4214

Altered T-bet dominance in IFN-γ-decoupled CD4+ T cells with attenuated cytokine storm and preserved memory in influenza

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GAMMA INTERFERON; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RETINOID RELATED ORPHAN RECEPTOR GAMMA T; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

EID: 84875983691     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202434     Document Type: Article
Times cited : (29)

References (35)
  • 1
    • 53749084847 scopus 로고    scopus 로고
    • Insights into inflammation and influenza
    • Simmons, C., and J. Farrar. 2008. Insights into inflammation and influenza. N. Engl. J. Med. 359: 1621-1623.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 1621-1623
    • Simmons, C.1    Farrar, J.2
  • 3
    • 0037038866 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: A mechanism for the unusual severity of human disease?
    • Cheung, C. Y., L. L. Poon, A. S. Lau, W. Luk, Y. L. Lau, K. F. Shortridge, S. Gordon, Y. Guan, and J. S. Peiris. 2002. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 360: 1831-1837.
    • (2002) Lancet , vol.360 , pp. 1831-1837
    • Cheung, C.Y.1    Poon, L.L.2    Lau, A.S.3    Luk, W.4    Lau, Y.L.5    Shortridge, K.F.6    Gordon, S.7    Guan, Y.8    Peiris, J.S.9
  • 8
    • 62049085168 scopus 로고    scopus 로고
    • Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10
    • Sun, J., R. Madan, C. L. Karp, and T. J. Braciale. 2009. Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat. Med. 15: 277-284.
    • (2009) Nat. Med. , vol.15 , pp. 277-284
    • Sun, J.1    Madan, R.2    Karp, C.L.3    Braciale, T.J.4
  • 9
    • 0017817193 scopus 로고
    • Antibody production and protection against influenza virus in immunodeficient mice
    • Lucas, S. J., D. W. Barry, and P. Kind. 1978. Antibody production and protection against influenza virus in immunodeficient mice. Infect. Immun. 20: 115-119.
    • (1978) Infect. Immun. , vol.20 , pp. 115-119
    • Lucas, S.J.1    Barry, D.W.2    Kind, P.3
  • 10
    • 0028177650 scopus 로고
    • Administration of anti-IFN-gamma antibody to beta 2-microglobulin- deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype
    • Sarawar, S. R., M. Sangster, R. L. Coffman, and P. C. Doherty. 1994. Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype. J. Immunol. 153: 1246-1253.
    • (1994) J. Immunol. , vol.153 , pp. 1246-1253
    • Sarawar, S.R.1    Sangster, M.2    Coffman, R.L.3    Doherty, P.C.4
  • 12
    • 0037037542 scopus 로고    scopus 로고
    • CD4 effector T cell subsets in the response to influenza: Heterogeneity, migration, and function
    • Román, E., E. Miller, A. Harmsen, J. Wiley, U. H. Von Andrian, G. Huston, and S. L. Swain. 2002. CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function. J. Exp. Med. 196: 957-968.
    • (2002) J. Exp. Med. , vol.196 , pp. 957-968
    • Román, E.1    Miller, E.2    Harmsen, A.3    Wiley, J.4    Von Andrian, U.H.5    Huston, G.6    Swain, S.L.7
  • 13
    • 24344435571 scopus 로고    scopus 로고
    • Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation
    • Jelley-Gibbs, D. M., D. M. Brown, J. P. Dibble, L. Haynes, S. M. Eaton, and S. L. Swain. 2005. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J. Exp. Med. 202: 697-706.
    • (2005) J. Exp. Med. , vol.202 , pp. 697-706
    • Jelley-Gibbs, D.M.1    Brown, D.M.2    Dibble, J.P.3    Haynes, L.4    Eaton, S.M.5    Swain, S.L.6
  • 14
    • 0021243967 scopus 로고
    • In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific
    • Lukacher, A. E., V. L. Braciale, and T. J. Braciale. 1984. In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J. Exp. Med. 160: 814-826.
    • (1984) J. Exp. Med. , vol.160 , pp. 814-826
    • Lukacher, A.E.1    Braciale, V.L.2    Braciale, T.J.3
  • 15
    • 0036911130 scopus 로고    scopus 로고
    • Dominant transplantation tolerance impairs CD8+ T cell function but not expansion
    • Lin, C. Y., L. Graca, S. P. Cobbold, and H. Waldmann. 2002. Dominant transplantation tolerance impairs CD8+ T cell function but not expansion. Nat. Immunol. 3: 1208-1213.
    • (2002) Nat. Immunol. , vol.3 , pp. 1208-1213
    • Lin, C.Y.1    Graca, L.2    Cobbold, S.P.3    Waldmann, H.4
  • 16
    • 2442456683 scopus 로고    scopus 로고
    • Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen
    • Chen, T. C., S. P. Cobbold, P. J. Fairchild, and H. Waldmann. 2004. Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen. J. Immunol. 172: 5900-5907.
    • (2004) J. Immunol. , vol.172 , pp. 5900-5907
    • Chen, T.C.1    Cobbold, S.P.2    Fairchild, P.J.3    Waldmann, H.4
  • 17
    • 4344657757 scopus 로고    scopus 로고
    • CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
    • Sarween, N., A. Chodos, C. Raykundalia, M. Khan, A. K. Abbas, and L. S. Walker. 2004. CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J. Immunol. 173: 2942-2951.
    • (2004) J. Immunol. , vol.173 , pp. 2942-2951
    • Sarween, N.1    Chodos, A.2    Raykundalia, C.3    Khan, M.4    Abbas, A.K.5    Walker, L.S.6
  • 21
    • 0033730069 scopus 로고    scopus 로고
    • T cell differentiation: A mechanistic view
    • Avni, O., and A. Rao. 2000. T cell differentiation: a mechanistic view. Curr. Opin. Immunol. 12: 654-659.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 654-659
    • Avni, O.1    Rao, A.2
  • 23
    • 12344269852 scopus 로고    scopus 로고
    • T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
    • Hwang, E. S., S. J. Szabo, P. L. Schwartzberg, and L. H. Glimcher. 2005. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science 307: 430-433.
    • (2005) Science , vol.307 , pp. 430-433
    • Hwang, E.S.1    Szabo, S.J.2    Schwartzberg, P.L.3    Glimcher, L.H.4
  • 24
    • 0037342749 scopus 로고    scopus 로고
    • GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet
    • Usui, T., R. Nishikomori, A. Kitani, and W. Strober. 2003. GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet. Immunity 18: 415-428.
    • (2003) Immunity , vol.18 , pp. 415-428
    • Usui, T.1    Nishikomori, R.2    Kitani, A.3    Strober, W.4
  • 25
    • 77951920474 scopus 로고    scopus 로고
    • The transcription factor GATA3 actively represses RUNX3 proteinregulated production of interferon-gamma
    • Yagi, R., I. S. Junttila, G. Wei, J. F. Urban, Jr., K. Zhao, W. E. Paul, and J. Zhu. 2010. The transcription factor GATA3 actively represses RUNX3 proteinregulated production of interferon-gamma. Immunity 32: 507-517.
    • (2010) Immunity , vol.32 , pp. 507-517
    • Yagi, R.1    Junttila, I.S.2    Wei, G.3    Urban Jr., J.F.4    Zhao, K.5    Paul, W.E.6    Zhu, J.7
  • 26
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver, C. T., R. D. Hatton, P. R. Mangan, and L. E. Harrington. 2007. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 27
    • 35348960243 scopus 로고    scopus 로고
    • Th17: The third member of the effector T cell trilogy
    • Bettelli, E., T. Korn, and V. K. Kuchroo. 2007. Th17: the third member of the effector T cell trilogy. Curr. Opin. Immunol. 19: 652-657.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 652-657
    • Bettelli, E.1    Korn, T.2    Kuchroo, V.K.3
  • 28
    • 33748174156 scopus 로고    scopus 로고
    • T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype
    • Mathur, A. N., H. C. Chang, D. G. Zisoulis, R. Kapur, M. L. Belladonna, G. S. Kansas, and M. H. Kaplan. 2006. T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 108: 1595-1601.
    • (2006) Blood , vol.108 , pp. 1595-1601
    • Mathur, A.N.1    Chang, H.C.2    Zisoulis, D.G.3    Kapur, R.4    Belladonna, M.L.5    Kansas, G.S.6    Kaplan, M.H.7
  • 30
    • 70349735887 scopus 로고    scopus 로고
    • Encephalitogenic T cells that stably express both T-bet and RORgt consistently produce IFN-gamma but have a spectrum of IL-17 profiles
    • Abromson-Leeman, S., R. T. Bronson, and M. E. Dorf. 2009. Encephalitogenic T cells that stably express both T-bet and RORgt consistently produce IFN-gamma but have a spectrum of IL-17 profiles. J. Neuroimmunol. 215: 10-24.
    • (2009) J. Neuroimmunol. , vol.215 , pp. 10-24
    • Abromson-Leeman, S.1    Bronson, R.T.2    Dorf, M.E.3
  • 31
    • 70350541521 scopus 로고    scopus 로고
    • T-bet inhibits the in vivo differentiation of parasite-specific CD4+ Th17 cells in a T cell-intrinsic manner
    • Guo, S., D. Cobb, and R. B. Smeltz. 2009. T-bet inhibits the in vivo differentiation of parasite-specific CD4+ Th17 cells in a T cell-intrinsic manner. J. Immunol. 182: 6179-6186.
    • (2009) J. Immunol. , vol.182 , pp. 6179-6186
    • Guo, S.1    Cobb, D.2    Smeltz, R.B.3
  • 32
    • 79951707725 scopus 로고    scopus 로고
    • Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation
    • Rivera, A., T. M. Hohl, N. Collins, I. Leiner, A. Gallegos, S. Saijo, J. W. Coward, Y. Iwakura, and E. G. Pamer. 2011. Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation. J. Exp. Med. 208: 369-381.
    • (2011) J. Exp. Med. , vol.208 , pp. 369-381
    • Rivera, A.1    Hohl, T.M.2    Collins, N.3    Leiner, I.4    Gallegos, A.5    Saijo, S.6    Coward, J.W.7    Iwakura, Y.8    Pamer, E.G.9
  • 33
    • 18944370055 scopus 로고    scopus 로고
    • Regulation of IFN-gamma production by B effector 1 cells: Essential roles for T-bet and the IFN-gamma receptor
    • Harris, D. P., S. Goodrich, A. J. Gerth, S. L. Peng, and F. E. Lund. 2005. Regulation of IFN-gamma production by B effector 1 cells: essential roles for T-bet and the IFN-gamma receptor. J. Immunol. 174: 6781-6790.
    • (2005) J. Immunol. , vol.174 , pp. 6781-6790
    • Harris, D.P.1    Goodrich, S.2    Gerth, A.J.3    Peng, S.L.4    Lund, F.E.5
  • 34
    • 33750439839 scopus 로고    scopus 로고
    • Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor
    • Haring, J. S., and J. T. Harty. 2006. Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor. Infect. Immun. 74: 6252-6263.
    • (2006) Infect. Immun. , vol.74 , pp. 6252-6263
    • Haring, J.S.1    Harty, J.T.2
  • 35
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
    • Joshi, N. S., W. Cui, A. Chandele, H. K. Lee, D. R. Urso, J. Hagman, L. Gapin, and S. M. Kaech. 2007. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27: 281-295.
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1    Cui, W.2    Chandele, A.3    Lee, H.K.4    Urso, D.R.5    Hagman, J.6    Gapin, L.7    Kaech, S.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.