Complement receptor 3 influences toll-like receptor 7/8-dependent inflammation: Implications for autoimmune diseases characterized by antibody reactivity to ribonucleoproteins

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 9077-9083

  Reed, Joanne H ^a   Jain, Manish ^a   Lee, Kristen ^a   Kandimalla, Ekambar R ^b   Faridi, Mohd Hafeez ^c   Buyon, Jill P ^a   Gupta, Vineet ^c   Clancy, Robert M ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HYBRIDON INC   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC ACTIVATION; AUTOIMMUNE DISEASE; GENETIC VARIANTS; HUMAN MACROPHAGES; INFLAMMATORY RESPONSE; RIBONUCLEOPROTEINS; SYSTEMIC LUPUS ERYTHEMATOSUS; TOLL-LIKE RECEPTORS;

MACROPHAGES; OLIGONUCLEOTIDES; PHYSIOLOGY; RNA;

ANTIBODIES;

CD11B ANTIGEN; CHEMICAL COMPOUND; COMPLEMENT COMPONENT C3 RECEPTOR; LEUKADHEDRIN 1; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLELE; ALLOSTERISM; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; GENOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD11B; AUTOIMMUNE DISEASES; CELL ADHESION; DOWN-REGULATION; GENE EXPRESSION REGULATION; HETEROZYGOTE; HUMANS; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MODELS, GENETIC; MYELOID DIFFERENTIATION FACTOR 88; RNA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

MURINAE;

EID: 84875973489     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.403303     Document Type: Article

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