Identification of novel agonists of the integrin CD11b/CD18

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 24, 2009, Pages 6902-6906

  Faridi, Mohd Hafeez ^a   Maiguel, Dony ^a   Barth, Constantinos J ^a   Stoub, Darren ^b   Day, Ruth ^b   Schürer, Stephan ^c   Gupta, Vineet ^a,d  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b ROLLINS COLLEGE   (United States)

^c UNIVERSITY OF MIAMI   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Agonist; CD11b CD18; Cell adhesion; Cell based assay; High throughput screening; Inflammation; Integrin; Mac 1

Indexed keywords

5 (FURAN 2YLMETHYLENE) 2,4 DI OXO THIAZOLIDONE; CD11B ANTIGEN; CD18 ANTIGEN; COMPLEMENT COMPONENT C3B; FIBRINOGEN; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; COMPUTER MODEL; CONCENTRATION RESPONSE; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR MECHANICS; PROTEIN BINDING; PROTEIN DOMAIN;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD11B; ANTIGENS, CD18; CACO-2 CELLS; CELL ADHESION; FURANS; HUMANS; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINEDIONES;

EID: 71849103682     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.077     Document Type: Article

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