Early growth response gene-1 and hypoxia-inducible factor-1α affect tumor metastasis via regulation of tissue factor

Acta Oncologica

Volumn 52, Issue 4, 2013, Pages 842-851

  Sun, Li ^a   Liu, Yang ^a   Lin, Sensen ^a   Shang, Jing ^a   Liu, Jin ^a   Li, Ji ^b   Yuan, Shengtao ^a   Zhang, Luyong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; SMALL INTERFERING RNA; THROMBOPLASTIN; TRANSCRIPTION FACTOR EGR 1; TRANSCRIPTION FACTOR SP1; VASCULOTROPIN; EARLY GROWTH RESPONSE GENE 1; PROTEIN; STIMULATING PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HYPOXIA; METASTASIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; TRANSIENT EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANGIOGENESIS; BREAST CANCER CELL LINE; CELL ADHESION; COCULTURE; GENETIC TRANSFECTION; MOLECULAR BIOLOGY; MOUSE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; BREAST NEOPLASMS; CARCINOMA; CELL HYPOXIA; CELLS, CULTURED; COCULTURE TECHNIQUES; EARLY GROWTH RESPONSE PROTEIN 1; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, NUDE; NEOPLASM METASTASIS; THROMBOPLASTIN;

EID: 84875964911     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2013.705890     Document Type: Article

References (31)

1. Hu ZW, G aren A. T argeting tissue factor on tumor vasculaRendothelial cellSand tumor cells for immunotherapy in mouse models of prostatic cancer. Proc NatLacad Sci USA 2001; 98: 12180-5.
2. Huang X, M olema G, K ing S. T umor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature. Science 1997; 275: 547-50.
3. Versteeg HH, Schaffner F, K erver M. I nhibition of tissue factor signaling suppresses tumor growth. Blood 2008; 111: 190-9.
4. Mackman N. G ene targeting in hemostasis: Tissue factor. Front Biosci 2001; 6: 208-15.
5. R ong Y, H u F, H uang RP, M ackman N, H orowitz JM, Jensen RL, et al. Early growth response gene-1 regulates hypoxia-induceDexpression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res 2006; 66: 7067-74.
6. Yan S F, Z ou Y S, G ao Y. T issue factor transcription driven by Egr-1 iSa critical mechanism of murine pulmonary fi brin deposition in hypoxia. Proc NatLacad Sci USA 1998; 95: 8298-303.
7. Cui MZ, Parry GC, O eth P. T ranscriptional regulation of the tissue factor gene in human epithelial cells is mediated by Sp1 anDegr-1. J Biol Chem 1996; 271: 2731-9.
8. Lin SS, S un L, H u JL, et al. C hemokine C-X-C motiFreceptor 6 contributes to cell migration during hypoxia. Cancer Lett 2009; 279: 108-17.
9. Shen BQ, L ee DY, C ortopassi KM, D amico LA, Z ioncheck TF. VasculaRendothelial growth factor KDR receptor signaling potentiates tumor necrosis factor-induced tissue factoRexpression in endothelial cells. J Biol Chem 2001; 276: 5281-6.
10. Sloan EK, P ouliot N, S tanley KL, C hia J, M oseley JM, H ards DK, et al. Tumor-specific expression of α v ? 3 integrin promotes spontaneous metastasis of breast cancer to bone. Breast Cancer Res 2006; 8: R20-34.
11. Guo K, L i J, W ang HH, O sato M, T ang JP, Q uah SY, et al. PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo. Cancer Res 2006; 66: 9625-35.
12. Miura M, S eki N, K oike T, I shihara T, N iimi T, H irayama F, et al. Design, synthesiSand biologicaLactivity of selective and orally available TF/FVIIa complex inhibitors containing non-amidine P1 ligands. Bioorg Med Chem 2007; 15: 160-73.
13. Yong J. A quaporin-1 activity of plasma membrane affects HT20 colon cancer cell migration. IUBMB Life 2009; 61: 1001-9.
14. Semenza L. H IF-1 and tumor progression: Pathophysiology G and therapeutics. Trends Mol Med 2002; 8: S62-7.
15. Haque I, B anerjee S, M ehta S, De A, M ajumder M, Mayo MS, et al. Cysteine-rich 61-connective tissue growth factor-nephroblastoma-overexpressed 5 (CCN5)/Wnt-1-induced signaling protein-2 (WISP-2) regulates microRNA-10b via hypoxia-inducible factor-1 a-TWISTsignaling networks in human breast cancer cells. J Biol Chem 2011; 286: 43475-85.
16. Du J, X u R, H u Z, T ian Y, Z hu Y, G u L, et a l. P I3K anDeRK-induced Rac1 activation mediates hypoxia-induced HIF-1 a expression in MCF-7 breast cancer cells. PLoS One 2011; 6: e25213.
17. Rong Y, P ost DE, P ieper RO, D urden DL, van MeiReG, Brat DJ. PTEN and hypoxia regulate tissue factoRexpression and plasma coagulation by glioblastoma. Cancer Res 2005; 65: 1406-13.
18. Shimoyamada H, Y azawa T, Sato H, O kudela K, I shii J, Sakaeda M, et al. Early growth response-1 induceSanDenhances vasculaRendothelial growth factor-A expression in lung cancer cells. Am J Pathol 2010; 177: 70-83.
19. Shin S Y, K im J H, B aker A, L im Y, L ee Y H. Transcription factoRegr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha. Mol Cancer Res 2010; 8: 507-19.
20. Schaffner F, Y okota N, R uf W. P L-27 Tissue factor proangiogenic signaling in cancer progression. Thromb Res 2012; 129: S127-31.
21. de Oliveira A D, L ima LG, M ariano-Oliveira A, Machado DE, Nasciutti LE, Andersen JF, et al. Inhibition of tissue factor by ixolaris reduces primary tumor growth anDexperimental metastasis in a murine model of melanoma. Thromb Res Epub 2012 Jun 9.
22. Ma Z, Z hang T, W ang R, C heng Z, X u H, L i W, et al. T issue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanism. Int J Gynecol Cancer 2011; 21: 616-24.
23. Rong Y, H u F, H uang R, M ackman N, H orowitz JM, Jensen RL, et al. Early growth response gene-1 regulates hypoxia-induceDexpression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res 2006; 66: 7067-74.
24. Kim J, M in JK, Park JA, D oh HJ, C hoi YS, R ho J, et al. Receptor activator of nuclear factor kappaB ligand iSa novel inducer of tissue factor in macrophages. Circ Res 2010; 107: 871-6.
25. Hu C, H uang L, G est C, X i X, J anin A, S oria C, et al. Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factoRexpression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells. J Hematol Oncol 2012; 5: 16.
26. Mechtcheriakova D, W lachoSa, H olzmuller H, B inder BR, HofeRe. VasculaRendothelial cell growth factor-induced tissue factoRexpression in endothelial cells is mediated by EGR-1. Blood 1999; 93: 3811-23.
27. Sarraj A, Day RM, T hiel G. S pecificity of transcriptional regulation by the zinc fi nger factors Sp1, Sp3, anDegr-1. J Cell Biochem 2005; 94: 153-67.
28. Rak J, Milsom C, Magnus N, Y u J. T issue factor in tumor progression. Best Pract Res Clin Haematol 2009; 22: 71-83.
29. White DE, Muller WJ. Multifaceted roles of integrins in breast cancer. J Mammary Gland Biol Neoplasia 2007; 12: 135-42.
30. Zhao W, W ang YS, H ui YN, Z hu J, Z hang P, L i X, et al. Inhibition of proliferation, migration and tube formation of choroidal microvasculaRendothelial cells by targeting HIF-1 alpha with short hairpin RNA-expressing plasmid DNA in human RPE cells in a coculture system. GraefeSarch Clin Exp Ophthalmol 2008; 246: 1413-22.
31. Forstera Y, Meyeb A l, A lbrechTs, K otzsch M, F ü ssel S, Wirth MP, et al. Tissue specific expression and serum levels of human tissue factor in patients with urological cancer. Cancer Lett 2003; 193: 65-73.