PL-27 tissue factor proangiogenic signaling in cancer progression

Thrombosis Research

Volumn 129, Issue SUPPL. 1, 2012, Pages

  Schaffner, Florence ^a   Yokota, Naho ^a   Ruf, Wolfram ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Angiogenensis; Coagulation factor VII; Metastasis; Protease activated receptor; Protein C receptor; Tissue factor

Indexed keywords

THROMBIN; THROMBOPLASTIN; BLOOD CLOTTING FACTOR;

ANGIOGENESIS; BLOOD CLOTTING; CANCER CELL; CANCER GROWTH; CELL INTERACTION; CONFERENCE PAPER; HEMOSTASIS; HUMAN; METASTASIS; PRIORITY JOURNAL; ANIMAL; CELL TRANSFORMATION; IMMUNOLOGY; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BLOOD COAGULATION FACTORS; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; THROMBOPLASTIN;

EID: 84862153516     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/S0049-3848(12)70032-4     Document Type: Conference Paper

References (77)

1. BM Mueller, RA Reisfeld, TS Edgington, W Ruf Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis Proc Natl Acad Sci USA 89 24 1992 11832 11836 (Pubitemid 23004738)
2. JS Palumbo, KE Talmage, JV Massari, CM La Jeunesse, MJ Flick, KW Kombrinck et al. Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and -independent mechanisms Blood 110 2007 133 141 (Pubitemid 47026828)
3. ME Bromberg, WH Konigsberg, JF Madison, A Pawashe, A Garen Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation Proc Natl Acad Sci USA 92 1995 8205 8209
4. BM Mueller, W Ruf Requirement for binding of catalytically active factor VIIa in tissue factor dependent experimental metastasis J Clin Invest 101 7 1998 1372 1378 (Pubitemid 28166834)
5. A Amirkhosravi, T Meyer, JY Chang, M Amaya, F Siddiqui, H Desai et al. Tissue factor pathway inhibitor reduces experimental lung metastasis of B16 melanoma Thromb Haemost 87 6 2002 930 936 (Pubitemid 34624872)
6. J Zhao, G Aguilar, S Palencia, E Newton, A Abo rNAPc2 inhibits colorectal cancer in mice through tissue factor Clin Cancer Res 15 1 2009 208 216
7. X Wang, M Wang, M Amarzguioui, F Liu, O Fodstad, H Prydz Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice Int J Cancer 112 6 2004 994 1002 (Pubitemid 39507005)
8. N Esumi, D Fan, IJ Fidler Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor Cancer Res 51 1991 4549 4556
9. E Camerer, AA Qazi, DN Duong, I Cornelissen, R Advincula, SR Coughlin Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis Blood 104 2 2004 397 401 (Pubitemid 38900020)
10. ML Nierodzik, S Karpatkin Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated dormant tumor phenotype Cancer Cell 10 5 2006 355 362 (Pubitemid 44693468)
11. B Nieswandt, M Hafner, B Echtenacher, DN Mannel Lysis of tumor cells by natural killer cells in mice is impeded by platelets Cancer Res 59 6 1999 1295 1300 (Pubitemid 29136261)
12. JS Palumbo, KE Talmage, JV Massari, CM La Jeunesse, MJ Flick, KW Kombrinck et al. Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer-mediated elimination of tumor cells Blood 105 1 2004 178 185 (Pubitemid 40053080)
13. GL Van Sluis, LW Bruggemann, CT Esmon, PW Kamphuisen, DJ Richel, HR Buller et al. Endogenous activated protein C is essential for immune-mediated cancer cell elimination from the circulation Cancer Lett 306 1 2011 106 110
14. NA Horowitz, EA Blevins, WM Miller, AR Perry, KE Talmage, ES Mullins et al. Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain Blood 118 10 2011 2889 2895
15. GL Van Sluis, TM Niers, CT Esmon, W Tigchelaar, DJ Richel, HR Buller et al. Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement Blood 114 9 2009 1968 1973
16. M Bezuhly, R Cullen, CT Esmon, SF Morris, KA West, B Johnston et al. Role of activated protein C and its receptor in inhibition of tumor metastasis Blood 113 14 2009 3371 3374
17. H Weiler-Guettler, PD Christie, DL Beeler, AM Healy, WW Hancock, H Rayburn et al. A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state J Clin Invest 101 9 1998 1983 1991 (Pubitemid 28226118)
18. M Shipitsin, LL Campbell, P Argani, S Weremowicz, N Bloushtain-Qimron, J Yao et al. Molecular definition of breast tumor heterogeneity Cancer Cell 11 3 2007 259 273 (Pubitemid 46349843)
19. WW Hwang-Verslues, WH Kuo, PH Chang, CC Pan, HH Wang, ST Tsai et al. Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers PLoS ONE 4 12 2009 e8377
20. LM Beaulieu, FC Church Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1 Exp Cell Res 313 4 2007 677 687 (Pubitemid 46198814)
21. C Feistritzer, M Riewald Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation Blood 105 8 2005 3178 3184
22. JH Finigan, SM Dudek, PA Singleton, ET Chiang, JR Jacobson, SM Camp et al. Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation J Biol Chem 280 17 2005 17286 17293 (Pubitemid 41389197)
23. GL Van Sluis, HR Buller, CA Spek The role of activated protein C in cancer progression Thromb Res 125 Suppl 2 2010 S138 S142
24. JH Im, W Fu, H Wang, SK Bhatia, DA Hammer, MA Kowalska et al. Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation Cancer Res 64 23 2004 8613 8619 (Pubitemid 39552074)
25. H Wang, W Fu, JH Im, Z Zhou, SA Santoro, V Iyer et al. Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis J Cell Biol 164 6 2004 935 941 (Pubitemid 38366904)
26. LJ Gay, B Felding-Habermann Contribution of platelets to tumour metastasis Nat Rev Cancer 11 2 2011 123 134
27. S Sabrkhany, AW Griffioen, MG oude Egbrink The role of blood platelets in tumor angiogenesis Biochim Biophys Acta 1815 2 2011 189 196
28. CA St Hill Interactions between endothelial selectins and cancer cells regulate metastasis Front Biosci 17 2011 3233 3251
29. B Shao, MG Wahrenbrock, L Yao, T David, SR Coughlin, L Xia et al. Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome Blood 118 15 2011 4015 4023
30. SR Barthel, JD Gavino, L Descheny, CJ Dimitroff Targeting selectins and selectin ligands in inflammation and cancer Expert Opin Ther Targets 11 11 2007 1473 1491 (Pubitemid 350200482)
31. M Chen, JG Geng P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis Arch Immunol Ther Exp (Warsz) 54 2 2006 75 84 (Pubitemid 44257345)
32. YJ Kim, L Borsig, NM Varki, A Varki P-selectin deficiency attenuates tumor growth and metastasis Proc Natl Acad Sci U S A 95 16 1998 9325 9330 (Pubitemid 28506230)
33. L Borsig, R Wong, RO Hynes, NM Varki, A Varki Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis Proc Natl Acad Sci U S A 99 4 2002 2193 2198 (Pubitemid 34169037)
34. B Monzavi-Karbassi, TL Whitehead, F Jousheghany, C Artaud, L Hennings, S Shaaf et al. Deficiency in surface expression of E-selectin ligand promotes lung colonization in a mouse model of breast cancer Int J Cancer 117 3 2005 398 408 (Pubitemid 41429563)
35. H Laubli, JL Stevenson, A Varki, NM Varki, L Borsig L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest Cancer Res 66 3 2006 1536 1542 (Pubitemid 43259935)
36. H Laubli, L Borsig Selectins as mediators of lung metastasis Cancer Microenviron 3 1 2010 97 105
37. L Biancone, M Araki, K Araki, P Vassalli, I Stamenkovic Redirection of tumor metastasis by expression of E-selectin in vivo J Exp Med 183 2 1996 581 587 (Pubitemid 26060792)
38. S Karpatkin, E Pearlstein, C Ambrogio, BS Coller Role of adhesive protein in platelet tumor interaction in vitro and metastasis formation in vivo J Clin Invest 81 1988 1012 1019
39. A Amirkhosravi, SA Mousa, M Amaya, S Blaydes, H Desai, T Meyer et al. Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb/IIIa antagonist XV454 Thromb Haemost 90 3 2003 549 554 (Pubitemid 37138780)
40. B Felding-Habermann, TE O'Toole, JW Smith, E Fransvea, ZM Ruggeri, MH Ginsberg et al. Integrin activation controls metastasis in human breast cancer Proc Natl Acad Sci U S A 98 4 2001 1853 1858 (Pubitemid 32165587)
41. C Cerletti, C Tamburrelli, B Izzi, F Gianfagna, GG de Platelet-leukocyte interactions in thrombosis Thromb Res 2011
42. P Zhang, T Ozdemir, CY Chung, GP Robertson, C Dong Sequential binding of alphaVbeta3 and ICAM-1 determines fibrin-mediated melanoma capture and stable adhesion to CD11b/CD18 on neutrophils J Immunol 186 1 2011 242 254
43. S Liang, M Hoskins, C Dong Tumor cell extravasation mediated by leukocyte adhesion is shear rate dependent on IL-8 signaling Mol Cell Biomech 7 2 2010 77 91
44. H Laubli, KS Spanaus, L Borsig Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes Blood 114 20 2009 4583 4591
45. BZ Qian, J Li, H Zhang, T Kitamura, J Zhang, LR Campion et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis Nature 475 7355 2011 222 225
46. EM Conn, MA Madsen, BF Cravatt, W Ruf, EI Deryugina, JP Quigley Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation J Biol Chem 283 39 2008 26518 26527
47. M Labelle, S Begum, RO Hynes Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis Cancer Cell 20 5 2011 576 590
48. Y Zhang, Y Deng, T Luther, M Müller, R Ziegler, R Waldherr et al. Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice J Clin Invest 94 1994 1320 1327 (Pubitemid 24286478)
49. JL Yu, L May, V Lhotak, S Shahrzad, S Shirasawa, JI Weitz et al. Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis Blood 105 4 2005 1734 1741 (Pubitemid 40223697)
50. AK Kakkar, V Chinswangwatanakul, NR Lemoine, S Tebbutt, RCN Williamson Role of tissue factor expression on tumour cell invasion and growth of experimental pancreatic adenocarcinoma Br J Surg 86 1999 890 894 (Pubitemid 29333012)
51. Y Liu, P Jiang, K Capkova, D Xue, L Ye, SC Sinha et al. Tissue factor-activated coagulation cascade in the tumor microenvironment is critical for tumor progression and an effective target for therapy Cancer Res 71 20 2011 6492 6502
52. W Ruf, J Disse, TC Carneiro-Lobo, N Yokota, F Schaffner Tissue factor and cell signalling in cancer progression and thrombosis J Thromb Haemost 9 Suppl 1 2011 306 315
53. S Koizume, M-S Jin, E Miyagi, F Hirahara, Y Nakamura, J-H Piao et al. Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII Cancer Res 66 19 2006 9453 9460 (Pubitemid 44623642)
54. S Koizume, N Yokota, E Miyagi, F Hirahara, Y Nakamura, Y Sakuma et al. Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases Mol Cancer Res 7 12 2009 1928 1936
55. N Magnus, D Garnier, J Rak Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells Blood 116 5 2010 815 818
56. GM Hjortoe, LC Petersen, T Albrektsen, BB Sorensen, PL Norby, SK Mandal et al. Tissue factor-factor VIIa specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated via PAR-2 and results in increased cell migration Blood 103 8 2004 3029 3037 (Pubitemid 38451676)
57. T Albrektsen, BB Sorensen, GM Hjortoe, J Fleckner, LVM Rao, LC Petersen Transcriptional program induced by factor VIIa-tissue factor, PAR1 and PAR2 in MDA-MB-231 cells J Thromb Haemost 5 2007 1588 1597 (Pubitemid 47091396)
58. HH Versteeg, F Schaffner, M Kerver, HH Petersen, J Ahamed, B Felding-Habermann et al. Inhibition of tissue factor signaling suppresses tumor growth Blood 111 1 2008 190 199
59. Y Liu, BM Mueller Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways Biochem Biophys Res Commun 344 4 2006 1263 1270
60. TC Carneiro-Lobo, S Konig, DE Machado, LE Nasciutti, MF Forni, IM Francischetti et al. Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model J Thromb Haemost 7 11 2009 1855 1864
61. F Gessler, V Voss, S Dutzmann, V Seifert, R Gerlach, D Kogel Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells Neuroscience 165 4 2010 1312 1322
62. KJ Svensson, P Kucharzewska, HC Christianson, S Skold, T Lofstedt, MC Johansson et al. Hypoxia triggers a pro-angiogenic pathway involving cancer cell microvesicles and PAR-2 mediated HB-EGF signaling in endothelial cells Proc Natl Acad Sci USA 108 2011 13147 13152
63. L Trusolino, A Bertotti, PM Comoglio MET signalling: principles and functions in development, organ regeneration and cancer Nat Rev Mol Cell Biol 11 12 2010 834 848
64. C Boccaccio, G Sabatino, E Medico, F Girolami, A Follenzi, G Reato et al. The MET oncogene drives a genetic programme linking cancer to haemostasis Nature 434 7031 2005 396 400 (Pubitemid 40469184)
65. EY Lin, JF Li, L Gnatovskiy, Y Deng, L Zhu, DA Grzesik et al. Macrophages regulate the angiogenic switch in a mouse model of breast cancer Cancer Res 66 23 2006 11238 11246 (Pubitemid 46009952)
66. HH Versteeg, F Schaffner, M Kerver, LG Ellies, P Andrade-Gordon, BM Mueller et al. Protease activated receptor (PAR)2, but not PAR1 signaling promotes the development of mammary adenocarcinoma in PyMT mice Cancer Res 68 17 2008 7219 7227
67. F Schaffner, HH Versteeg, A Schillert, N Yokota, LC Petersen, BM Mueller et al. Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development Blood 116 26 2010 6106 6113
68. L Ryden, D Grabau, F Schaffner, PE Jonsson, W Ruf, M Belting Evidence for tissue factor phosphorylation and its correlation with protease activated receptor expression and the prognosis of primary breast cancer Int J Cancer 126 10 2010 2330 2340
69. M Belting, MI Dorrell, S Sandgren, E Aguilar, J Ahamed, A Dorfleutner et al. Regulation of angiogenesis by tissue factor cytoplasmic domain signaling Nature Med 10 5 2004 502 509 (Pubitemid 38667909)
70. H Uusitalo-Jarvinen, T Kurokawa, BM Mueller, P Andrade-Gordon, M Friedlander, W Ruf Role of Protease Activated Receptor 1 and 2 Signaling in Hypoxia-Induced Angiogenesis Arterioscler Thromb Vasc Biol 27 6 2007 1456 1462 (Pubitemid 46809438)
71. J Ahamed, HH Versteeg, M Kerver, VM Chen, BM Mueller, PJ Hogg et al. Disulfide isomerization switches tissue factor from coagulation to cell signaling Proc Natl Acad Sci USA 103 38 2006 13932 13937 (Pubitemid 44452960)
72. MA Gimbrone Jr., SB Leapman, RS Cotran, J Folkman Tumor dormancy in vivo by prevention of neovascularization J Exp Med 136 2 1972 261 276
73. C Fischer, B Jonckx, M Mazzone, S Zacchigna, S Loges, L Pattarini et al. Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels Cell 131 3 2007 463 475 (Pubitemid 350007692)
74. L Witte, DJ Hicklin, Z Zhu, B Pytowski, H Kotanides, P Rockwell et al. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy Cancer Metastasis Rev 17 2 1998 155 161 (Pubitemid 28391949)
75. R Srinivasan, E Ozhegov, YW van den Berg, BJ Aronow, RS Franco, MB Palascak et al. Splice Variants of Tissue Factor Promote Monocyte-Endothelial Interactions by Triggering the Expression of Cell Adhesion Molecules via Integrin-Mediated Signaling J Thromb Haemost 2011 in press.
76. YW van den Berg, LG van den Hengel, HR Myers, O Ayachi, E Jordanova, W Ruf et al. Alternatively spliced tissue factor induces angiogenesis through integrin ligation Proc Natl Acad Sci U S A 106 46 2009 19497 19502
77. Y Saito, Y Hashimoto, J Kuroda, M Yasunaga, Y Koga, A Takahashi et al. The inhibition of pancreatic cancer invasion-metastasis cascade in both cellular signal and blood coagulation cascade of tissue factor by its neutralisation antibody Eur J Cancer 47 14 2011 2230 2239