Valsartan attenuates oxidative stress and NF-κB activation and reduces myocardial apoptosis after ischemia and reperfusion

European Journal of Pharmacology

Volumn 705, Issue 1-3, 2013, Pages 140-147

  Wu, Bing ^a   Lin, Rong ^a   Dai, Ruozhu ^a   Chen, Chengbo ^a   Wu, Haiyun ^a   Hong, Meiman ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin II; Apoptosis; Ischemia reperfusion; Nicotinamide Adenine Dinucleotide phosphate oxidase; Nuclear factor kappa B

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; VALSARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; INTRACELLULAR TRANSPORT; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REPERFUSION INJURY; TRANSCRIPTION INITIATION; TREATMENT DURATION; TUMOR NECROSIS FACTOR ALPHA BLOOD LEVEL;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; APOPTOSIS; CASPASE 3; MALE; MALONDIALDEHYDE; MYOCARDIAL REPERFUSION INJURY; NADPH OXIDASE; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TETRAZOLES; TUMOR NECROSIS FACTOR-ALPHA; VALINE;

EID: 84875944140     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.036     Document Type: Article

References (33)

1. A. Abbate, C. Morales, M. De Falco, V. Fedele, G.G. Biondi Zoccai, D. Santini, J. Palleiro, F. Vasaturo, S. Scarpa, G. Liuzzo, A. Severino, F. Baldi, F. Crea, L.M. Biasucci, G.W. Vetrovec, R.J. Gelpi, and A. Baldi Ischemia and apoptosis in an animal model of permanent infarct-related artery occlusion Int. J. Cardiol. 121 2007 109 111
2. P. Anversa, W. Cheng, Y. Liu, A. Leri, G. Redaelli, and J. Kajstura Apoptosis and myocardial infarction Basic Res. Cardiol. 93 Supplement 3 1998 S8 S12
3. C. Berthonneche, T. Sulpice, F. Boucher, L. Gouraud, J. de Leiris, S.E. O'Connor, J.M. Herbert, and P. Janiak New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats Am. J. Physiol. Heart Circ. Physiol. 287 2004 H340 350
4. C. Berthonneche, T. Sulpice, S. Tanguy, S. O'Connor, J.M. Herbert, P. Janiak, J. de Leiris, and F. Boucher AT1 receptor blockade prevents cardiac dysfunction after myocardial infarction in rats Cardiovasc. Drugs Ther. 19 2005 251 259
5. J. Chandra, A. Samali, and S. Orrenius Triggering and modulation of apoptosis by oxidative stress Free Radical Biol. Med. 29 2000 323 333
6. Y. Chandrashekhar, S. Sen, Ruth. Anway, A. Shuros, and I. Anand Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction J. Am. Coll. Cardiol. 43 2004 295 301
7. P. Dandona, V. Kumar, A. Aljada, H. Ghanim, T. Syed, D. Hofmayer, P. Mohanty, D. Tripathy, and R. Garg Angiotensin II receptor blocker valsartan suppresses reactive oxygen species generation in leukocytes, nuclear factor-kappa B, in mononuclear cells of normal subjects: evidence of an antiinflammatory action J. Clin. Endocrinol. Metab. 88 2003 4496 4501
8. Q. Du, S. Jovanovic, A. Clelland, A. Sukhodub, G. Budas, K. Phelan, V. Murray-Tait, L. Malone, and A. Jovanovic Overexpression of SUR2A generates a cardiac phenotype resistant to ischemia FASEB J. 20 2006 1131 1141
9. L. Flohe, R. Brigelius-Flohe, C. Saliou, M.G. Traber, and L. Packer Redox regulation of NF-kappa B activation Free Radical Biol. Med. 22 1997 1115 1126
10. R.A. Gottlieb, K.O. Burleson, R.A. Kloner, B.M. Babior, and R.L. Engler Reperfusion injury induces apoptosis in rabbit cardiomyocytes J. Clin. Invest. 94 1994 1621 1628
11. K.K. Griendling, D. Sorescu, and M. Ushio-Fukai NAD(P)H oxidase: role in cardiovascular biology and disease Circ. Res. 86 2000 494 501
12. P.A. MacCarthy, and A.M. Shah Oxidative stress and heart failure Coron. Artery Dis. 14 2003 109 113
13. K. Matsumura, R.W. Jeremy, J. Schaper, and L.C. Becker Progression of myocardial necrosis during reperfusion of ischemic myocardium Circulation 97 1998 795 804
14. D. Ma, L. Fu, J. Shen, P. Zhou, Y. Gao, R. Xie, Y. Li, Y. Han, Y. Wang, and F. Wang Intervential effect of valsartan on expression of inducible cAMP early repressor and phosphodiesterase 3A in rats after myocardial infarction Eur. J. Pharmacol. 602 2009 348 354
15. D.R. Meldrum Tumor necrosis factor in the heart Am. J. Physiol. 274 1998 R577 595
16. E. Messadi-Laribi, V. Griol-Charhbili, A. Pizard, M.P. Vincent, D. Heudes, P. Meneton, F. Alhenc-Gelas, and C. Richer Tissue kallikrein is involved in the cardioprotective effect of AT1-receptor blockade in acute myocardial ischemia J. Pharmacol. Exp. Ther. 323 2007 210 216
17. M.M. Mocanu, G.F. Baxter, and D.M. Yellon Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury Br. J. Pharmacol. 130 2000 197 200
18. M.K. Ozer, E. Sahna, M. Birincioglu, and A. Acet Effects of captopril and losartan on myocardial ischemia-reperfusion induced arrhythmias and necrosis in rats Pharmacol. Res. 45 2002 257 263
19. S. Rajagopalan, S. Kurz, T. Munzel, M. Tarpey, B.A. Freeman, K.K. Griendling, and D.G. Harrison Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone J. Clin. Invest. 97 1996 1916 1923
20. M. Sato, R.M. Engelman, H. Otani, N. Maulik, J.A. Rousou, J.E. Flack 3rd, D.W. Deaton, and D.K. Das Myocardial protection by preconditioning of heart with losartan, an angiotensin II type 1-receptor blocker: implication of bradykinin-dependent and bradykinin-independent mechanisms Circulation 102 2000 III346 III351
21. G. Sawicki, and B.I. Jugdutt Valsartan reverses post-translational modifications of the delta-subunit of ATP synthase during in vivo canine reperfused myocardial infarction Proteomics 7 2007 2100 2110
22. T. Scarabelli, A. Stephanou, N. Rayment, E. Pasini, L. Comini, S. Curello, R. Ferrari, R. Knight, and D. Latchman Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury Circulation 104 2001 253 256
23. J.P. Schmitt, J. Schroder, H. Schunkert, D.E. Birnbaum, and H. Aebert Role of apoptosis in myocardial stunning after open heart surgery Ann. Thorac. Surg. 73 2002 1229 1235
24. A. Sukhodub, S. Jovanovi, Q. Du, G. Budas, A.K. Clelland, M. Shen, K. Sakamoto, R. Tian, and A. Jovanovic AMP-activated protein kinase mediates preconditioning in cardiomyocytes by regulating activity and trafficking of sarcolemmal ATP-sensitive K+ channels J. Cell Physiol. 210 2007 224 236
25. A. Sukhodub, R. Sudhir, Q. Du, S. Jovanovic, and A. Jovanovic Nicotinamide-rich diet improves physical endurance by upregulating SUR2A in the heart J. Cell Mol. Med. 15 2010 1703 1712
26. Y. Suzuki, O. Lopez-Franco, D. Gomez-Garre, N. Tejera, C. Gomez-Guerrero, T. Sugaya, R. Bernal, J. Blanco, L. Ortega, and J. Egido Renal tubulointerstitial damage caused by persistent proteinuria is attenuated in AT1-deficient mice: role of endothelin-1 Am. J. Pathol. 159 2001 1895 1904
27. J.E. Thompson, R.J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B Cell 80 1995 573 582
28. M. Wang, B.M. Tsai, P.R. Crisostomo, and D.R. Meldrum Tumor necrosis factor receptor 1 signaling resistance in the female myocardium during ischemia Circulation 114 2006 I282 289
29. J. Yang, H. Jiang, J. Yang, J.W. Ding, L.H. Chen, S. Li, and X.D. Zhang Valsartan preconditioning protects against myocardial ischemia-reperfusion injury through TLR4/FN-kabbaB signaling pathway Mol. Cell Biochem. 330 2009 39 46
30. G.X. Zhang, S. Kimura, A. Nishiyama, T. Shokoji, M. Rahman, and Y. Abe ROS during the acute phase of Ang II hypertension participates in cardiovascular MAPK activation but not vasoconstriction Hypertension 43 2004 117 124
31. Z.Q. Zhao, C.D. Morris, J.M. Budde, N.P. Wang, S. Muraki, H.Y. Sun, and R.A. Guyton Inhibition of myocardial apoptosis reduces infarct size and improves regional contractile dysfunction during reperfusion Cardiovasc. Res. 59 2003 132 142
32. Z.Q. Zhao, M. Nakamura, N.P. Wang, J.N. Wilcox, S. Shearer, R.S. Ronson, R.A. Guyton, and J. Vinten-Johansen Reperfusion induces myocardial apoptotic cell death Cardiovasc. Res. 45 2000 651 660
33. J.L. Zweier, and M.A. Talukder The role of oxidants and free radicals in reperfusion injury Cardiovasc. Res. 70 2006 181 190