EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: Importance in IL-8 transcription

Pulmonary Pharmacology and Therapeutics

Volumn 26, Issue 3, 2013, Pages 318-324

  Li, Ying Ji ^a   Shimizu, Takako ^a   Hirata, Yukiyo ^a   Inagaki, Hirofumi ^a   Takizawa, Hajime ^b   Azuma, Arata ^a   Kawada, Tomoyuki ^a   Sugawara, Isamu ^c   Kudoh, Shoji ^a,d   Sunazuka, Toshiaki ^e   Omura, Satoshi ^e  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b KYORIN UNIVERSITY   (Japan)

^c RESEARCH INSTITUTE OF TUBERCULOSIS   (Japan)

^d Japan Anti Tuberculosis Association   (Japan)

^e KITASATO UNIVERSITY   (Japan)

Author keywords

Diesel exhaust particle (DEP); EM EM703; Human bronchial epithelial cells; IL 8; NF kB; Oxidative stress

Indexed keywords

EM 703; ERYTHROMYCIN; ERYTHROMYCIN DERIVATIVE; INTERLEUKIN 8; MESSENGER RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LINE; DRUG INHIBITION; EPITHELIUM CELL; EXHAUST GAS; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTI-INFLAMMATORY AGENTS; CELL LINE; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; ERYTHROMYCIN; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-8; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PARTICULATE MATTER; VEHICLE EMISSIONS;

EID: 84875933403     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2012.12.010     Document Type: Article

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