EM703, a new derivative of erythromycin, inhibits transforming grwth factor-β signaling in human lung fibroblasts

Experimental Lung Research

Volumn 34, Issue 6, 2008, Pages 343-354

  Yu, ChangHe ^a   Azuma, Arata ^a   Li, Yingji ^a   Wang, Chunyan ^a   Abe, Sinji ^a   Usuki, Jiro ^a   Matsuda, Kuniko ^a   Kudoh, Shoji ^a   Sunazuka, Toshiaki ^b   Omura, Satoshi ^b  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b KITASATO INSTITUTE   (Japan)

Author keywords

EM703; Fibroblast; IPF; Macrolides; Smad; TGF

Indexed keywords

EM 703; ERYTHROMYCIN; ERYTHROMYCIN DERIVATIVE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL ASSAY; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTI-BACTERIAL AGENTS; ANTIFIBRINOLYTIC AGENTS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; COLLAGEN; DRUG COMBINATIONS; ERYTHROMYCIN; FIBROBLASTS; GENE EXPRESSION; HUMANS; PHOSPHORYLATION; RNA, MESSENGER; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 46749094189     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140802093238     Document Type: Article

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