Alginic Acid-Coated Chitosan Nanoparticles Loaded with Legumain DNA Vaccine: Effect against Breast Cancer in Mice

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Liu, Ze ^a   Lv, Dan ^a,b   Liu, Shu ^a   Gong, Junbo ^c   Wang, Da ^a   Xiong, Min ^a   Chen, Xiaoniao ^a   Xiang, Rong ^a   Tan, Xiaoyue ^a  

^a NANKAI UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c TIANJIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; CD3 ANTIGEN; CD8 ANTIGEN; CHITOSAN; COBALT CHLORIDE; DNA VACCINE; ENHANCED GREEN FLUORESCENT PROTEIN; INTERLEUKIN 2 RECEPTOR ALPHA; LEGUMAIN DNA VACCINE; NANOPARTICLE; UNCLASSIFIED DRUG;

ACIDITY; AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; BREAST CANCER; CANCER INHIBITION; CANCER SIZE; CELL MEMBRANE; CELL STIMULATION; COCULTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; CYTOTOXIC T LYMPHOCYTE; DNA DEGRADATION; DRUG COATING; DRUG EFFICACY; DRUG SAFETY; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PARTICLE SIZE; PEYER PATCH; PH; PLASMID; PROTECTION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SALMONELLA TYPHIMURIUM; SPLEEN CELL;

ALGINATES; ANIMALS; ANTIGEN-PRESENTING CELLS; BIOLOGICAL TRANSPORT; CANCER VACCINES; CELL PROLIFERATION; CHITOSAN; CYSTEINE ENDOPEPTIDASES; DRUG CARRIERS; FEMALE; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; MACROPHAGES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NANOPARTICLES; PEYER'S PATCHES; STOMACH; T-LYMPHOCYTES; VACCINES, DNA;

MURINAE; MUS; SALMONELLA TYPHIMURIUM;

EID: 84875928770     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060190     Document Type: Article

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