Delivery of a cocktail DNA vaccine encoding cysteine proteinases type I, II and III with solid lipid nanoparticles potentiate protective immunity against Leishmania major infection

Journal of Controlled Release

Volumn 153, Issue 2, 2011, Pages 154-162

  Doroud, Delaram ^a,b   Zahedifard, Farnaz ^a   Vatanara, Alireza ^b   Najafabadi, Abdolhossein Rouholamini ^b   Taslimi, Yasaman ^a   Vahabpour, Rouholah ^a   Torkashvand, Fatemeh ^a   Vaziri, Behrooz ^a   Rafati, Sima ^a  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cationic solid lipid nanoparticles; Cocktail DNA vaccine; Cysteine proteinases; Delivery system; Leishmania

Indexed keywords

COCKTAIL DNA VACCINE; CYSTEINE PROTEINASE; DELIVERY SYSTEMS; LEISHMANIA; SOLID LIPID NANOPARTICLES;

AMINO ACIDS; ENCODING (SYMBOLS); IMMUNOLOGY; MAMMALS; NANOPARTICLES;

VACCINES;

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE I; CYSTEINE PROTEINASE II; CYSTEINE PROTEINASE III; DNA VACCINE; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA IMMUNIZATION; FEMALE; FOOT PAD; INJECTION SITE; LEISHMANIA MAJOR; LEISHMANIASIS; MOUSE; NANOPHARMACEUTICS; NONHUMAN; PRIORITY JOURNAL; TH1 CELL;

ANIMALS; ANTIBODY FORMATION; CYSTEINE ENDOPEPTIDASES; FEMALE; IMMUNOGLOBULIN G; INTERFERON-GAMMA; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LIPIDS; MICE; MICE, INBRED BALB C; NANOPARTICLES; VACCINATION; VACCINES, DNA;

EID: 79960109323     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.04.011     Document Type: Article

References (26)

1. C.B. Palatnik-de-Sousa Vaccines for leishmaniasis in the fore coming 25 years Vaccine 26 2008 1709 1724
2. J.A. Carvalho, J. Rodgers, J. Atouguia, D.M. Prazeres, and G.A. Monteiro DNA vaccines: a rational design against parasitic diseases Expert Rev. Vaccines 9 2 2010 175 191
3. G.H. Coombs, and J.C. Mottram Proteinases of trypanosomes and Leishmania Trypanosomiasis and Leishmaniasis: Biology and Control 1997 CAB International Oxford 177
4. J.A. Sakanari, S.A. Nadler, V.J. Chan, J.C. Engel, C. Leptak, and J. Bouvier Leishmania major: comparison of the cathepsin L- and B-like cysteine protease genes with those of other trypanosomatids Exp. Parasitol. 85 1997 63 67
5. C.D. Robertson, G.H. Coombs, M.J. North, and J.C. Mottram Parasite cysteine proteinases J.H. McKerrow, M.N.G. James, Perspectives in Drug Discovery and Design 6 1996 ESCOM Science Publisher 99
6. S. Rafati, N. Fasel, and S. Masina Leishmania cysteine proteinases: from gene to subunit vaccine Curr. Genomics 4 2003 253 261 (Pubitemid 36348202)
7. N. Khoshgoo, F. Zahedifard, H. Azizi, Y. Taslimi, M. Jiménez Alonso, and S. Rafati Cysteine proteinase type III is protective against Leishmania infantum infection in BALB/c mice and highly antigenic in visceral leishmaniasis in individuals Vaccine 26 46 2008 5822 5829
8. S. Rafati, A. Nakhaee, T. Taheri, Y. Taslimi, H. Darabi, and D. Eravani Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum Vaccine 23 2005 3716 3725 (Pubitemid 40692418)
9. S. Rafati, F. Zahedifard, and F. Nazgouee Prime-boost vaccination using cysteine proteinases types I and II of Leishmania infantum confers protective immunity in murine visceral leishmaniasis Vaccine 24 2006 2169 2175 (Pubitemid 43255160)
10. S. Rafati, A.H. Salmanian, T. Taheri, M. Vafa, and N. Fasel A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major Vaccine 19 2001 3369 3375 (Pubitemid 32710285)
11. A. Zadeh-Vakili, T. Taheri, Y. Taslimi, F. Doustdari, A.H. Salmanian, and S. Rafati Immunization with the hybrid protein vaccine, consisting of Leishmania major cysteine proteinases Type I (CPB) and Type II (CPA), partially protects against leishmaniasis Vaccine 22 2004 1930 1940 (Pubitemid 38581062)
12. R.H. Muller, K. Mader, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery-a review of the state of the art Eur. J. Pharm. Biopharm. 50 2000 161 177 (Pubitemid 30326695)
13. D. Doroud, A. Vatanara, F. Zahedifard, E. Gholami, R. Vahabpour, A.H. Rouholamini Najafabadi, and S. Rafati Cationic solid lipid nanoparticles loaded by cysteine proteinase genes as a novel anti-leishmaniasis DNA vaccine delivery system: characterization and in vitro evaluations J. Pharm. Pharm. Sci. 13 3 2010 320 335
14. J.M. Mutiso, J.C. Macharia, and M.M. Gicheru A review of adjuvants for Leishmania vaccine candidates J. Biomed. Res. 24 1 2010 16 25
15. S.G. Reed, S. Bertholet, R.N. Coler, and M. Friede New horizons in adjuvants for vaccine development Trends Immunol. 30 2009 23 32
16. S. Bhowmick, and N. Ali Recent developments in leishmaniasis vaccine delivery systems Expert Opin. Drug Deliv. 5 7 2008 789 803
17. S. Ben Hadj Ahmed, L. Touihri, Y. Chtourou, K. Dellagi, and C. Bahloul DNA based vaccination with a cocktail of plasmids encoding immunodominant Leishmania (Leishmania) major antigens confers full protection in BALB/c mice Vaccine 27 2009 99 106
18. M.D. Joshi, and R.H. Müller Lipid nanoparticles for parenteral delivery of actives Eur. J. Pharm. Biopharm. 71 2009 161 172
19. R.S. Mehta, R. Huang, M. Yang, X.Q. Zhang, B. Kolli, K.P. Chang, R.M. Hoffman, Y. Goto, R. Badaro, and R.T. Schooley Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery Clin. Vaccine Immunol. 15 2008 1764 1770
20. A. Bolhassani, T. Taheri, Y. Taslimi, S. Zamanilui, F. Zahedifard, N. Seyed, F. Torkashvand, B. Vaziri, and S. Rafati Fluorescent Leishmania species: Development of stable GFP expression and its application for in vitro and in vivo studies Exp. Parasitol. 127 2011 637 645
21. J.M. Brewer, L. Tetley, J. Richmond, F.Y. Liew, and J. Alexander Cellular immunology and immune regulation: lipid vesicle size determines the Th1 or Th2 response to entrapped antigen J. Immunol. 161 1998 4000 4007 (Pubitemid 28468977)
22. L. Xu, and T.J. Anchordoquy Cholesterol domains in cationic lipid/DNA complexes improve transfection Biochim. Biophys. Acta (BBA) Biomembr. 1778 10 2008 2177 2181
23. F. Seeballuck, E. Lawless, M.B. Ashford, and C.M. O'Driscoll Stimulation of triglyceride-rich lipoprotein secretion by polysorbate 80: in vitro and in vivo correlation using caco-2 cells and a cannulated rat intestinal lymphatic model Pharm. Res. 21 2004 2320 2326 (Pubitemid 40568446)
24. D.P. Vangasseri, Z. Cui, W. Chen, D.A. Hokey, L.D. Falo, and L. Huang Immuno stimulation of dendritic cells by cationic liposomes Mol. Membr. Biol. 23 5 2006 385 395 (Pubitemid 44630022)
25. W. Yan, W. Chen, and L. Huang Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokines Mol. Immunol. 44 15 2007 3672 3681 (Pubitemid 46817670)
26. D. Doroud, F. Zahedifard, A. Vatanara, A.R. Najafabadi, and S. Rafati Cysteine proteinase type I, encapsulated in Solid Lipid Nanoparticles induces substantial protection against L. major infection in C57BL/6 mice Parasite Immunol. 33 6 2011 335 348