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Volumn 9, Issue 1, 2013, Pages

Gender, variation in opioid receptor genes and sensitivity to experimental pain

Author keywords

Gender; Opioid receptor genes; OPRD; OPRK; OPRM; Pain tolerance thresholds

Indexed keywords

DELTA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR;

EID: 84875909950     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-9-20     Document Type: Article
Times cited : (43)

References (54)
  • 1
    • 77955764740 scopus 로고    scopus 로고
    • Pain reporting at different body sites is explained by a single underlying genetic factor
    • Williams FM, Spector TD, MacGregor AJ. Pain reporting at different body sites is explained by a single underlying genetic factor. Rheumatology (Oxford) 2010, 49(9):1753-1755.
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.9 , pp. 1753-1755
    • Williams, F.M.1    Spector, T.D.2    MacGregor, A.J.3
  • 2
    • 80052462548 scopus 로고    scopus 로고
    • Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study
    • 10.1136/ard.2010.137836, 3171106, 21646416
    • Livshits G, Popham M, Malkin I, Sambrook PN, MacGregor AJ, Spector T. Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study. Ann Rheum Dis 2011, 70(10):1740-1745. 10.1136/ard.2010.137836, 3171106, 21646416.
    • (2011) Ann Rheum Dis , vol.70 , Issue.10 , pp. 1740-1745
    • Livshits, G.1    Popham, M.2    Malkin, I.3    Sambrook, P.N.4    MacGregor, A.J.5    Spector, T.6
  • 3
    • 70349759521 scopus 로고    scopus 로고
    • Heritability of spinal pain and consequences of spinal pain: a comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20-71 years
    • 10.1002/art.24607, 19790135
    • Hartvigsen J, Nielsen J, Kyvik KO, Fejer R, Vach W, Iachine I. Heritability of spinal pain and consequences of spinal pain: a comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20-71 years. Arthritis Rheum 2009, 61(10):1343-1351. 10.1002/art.24607, 19790135.
    • (2009) Arthritis Rheum , vol.61 , Issue.10 , pp. 1343-1351
    • Hartvigsen, J.1    Nielsen, J.2    Kyvik, K.O.3    Fejer, R.4    Vach, W.5    Iachine, I.6
  • 4
    • 35648960241 scopus 로고    scopus 로고
    • Heritability of responses to painful stimuli in women: a classical twin study
    • Norbury TA, MacGregor AJ, Urwin J, Spector TD, McMahon SB. Heritability of responses to painful stimuli in women: a classical twin study. Brain 2007, 130(Pt 11):3041-3049.
    • (2007) Brain , vol.130 , Issue.PART 11 , pp. 3041-3049
    • Norbury, T.A.1    MacGregor, A.J.2    Urwin, J.3    Spector, T.D.4    McMahon, S.B.5
  • 5
    • 41749112010 scopus 로고    scopus 로고
    • Individual differences in pain sensitivity: genetic and environmental contributions
    • Nielsen CS, Stubhaug A, Price DD, Vassend O, Czajkowski N, Harris JR. Individual differences in pain sensitivity: genetic and environmental contributions. Pain 2008, 136(1-2):21-29.
    • (2008) Pain , vol.136 , Issue.1-2 , pp. 21-29
    • Nielsen, C.S.1    Stubhaug, A.2    Price, D.D.3    Vassend, O.4    Czajkowski, N.5    Harris, J.R.6
  • 7
    • 33845901486 scopus 로고    scopus 로고
    • An SCN9A channelopathy causes congenital inability to experience pain
    • 10.1038/nature05413, 17167479
    • Cox JJ, Reimann F, Nicholas AK, Thornton G, Roberts E, Springell K. An SCN9A channelopathy causes congenital inability to experience pain. Nature 2006, 444(7121):894-898. 10.1038/nature05413, 17167479.
    • (2006) Nature , vol.444 , Issue.7121 , pp. 894-898
    • Cox, J.J.1    Reimann, F.2    Nicholas, A.K.3    Thornton, G.4    Roberts, E.5    Springell, K.6
  • 8
    • 33847168937 scopus 로고    scopus 로고
    • SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes
    • 10.1016/j.neuron.2006.10.006, 17145499
    • Fertleman CR, Baker MD, Parker KA, Moffatt S, Elmslie FV, Abrahamsen B. SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 2006, 52(5):767-774. 10.1016/j.neuron.2006.10.006, 17145499.
    • (2006) Neuron , vol.52 , Issue.5 , pp. 767-774
    • Fertleman, C.R.1    Baker, M.D.2    Parker, K.A.3    Moffatt, S.4    Elmslie, F.V.5    Abrahamsen, B.6
  • 9
    • 77954173921 scopus 로고    scopus 로고
    • A critical appraisal of human genotyping for pain therapy
    • 10.1016/j.tips.2010.04.002, 20483491
    • Lotsch J, Geisslinger G. A critical appraisal of human genotyping for pain therapy. Trends Pharmacol Sci 2010, 31(7):312-317. 10.1016/j.tips.2010.04.002, 20483491.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.7 , pp. 312-317
    • Lotsch, J.1    Geisslinger, G.2
  • 10
    • 66749154689 scopus 로고    scopus 로고
    • Dissociation of the opioid receptor mechanisms that control mechanical and heat pain
    • 10.1016/j.cell.2009.04.019, 19524516
    • Scherrer G, Imamachi N, Cao YQ, Contet C, Mennicken F, O'Donnell D. Dissociation of the opioid receptor mechanisms that control mechanical and heat pain. Cell 2009, 137(6):1148-1159. 10.1016/j.cell.2009.04.019, 19524516.
    • (2009) Cell , vol.137 , Issue.6 , pp. 1148-1159
    • Scherrer, G.1    Imamachi, N.2    Cao, Y.Q.3    Contet, C.4    Mennicken, F.5    O'Donnell, D.6
  • 11
    • 58149263474 scopus 로고    scopus 로고
    • Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*
    • 10.1111/j.1365-2044.2008.05760.x, 19032295
    • Huang CJ, Liu HF, Su NY, Hsu YW, Yang CH, Chen CC. Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*. Anaesthesia 2008, 63(12):1288-1295. 10.1111/j.1365-2044.2008.05760.x, 19032295.
    • (2008) Anaesthesia , vol.63 , Issue.12 , pp. 1288-1295
    • Huang, C.J.1    Liu, H.F.2    Su, N.Y.3    Hsu, Y.W.4    Yang, C.H.5    Chen, C.C.6
  • 12
    • 14944361565 scopus 로고    scopus 로고
    • The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans
    • 10.1016/j.jpain.2004.11.008, 15772909
    • Fillingim RB, Kaplan L, Staud R, Ness TJ, Glover TL, Campbell CM. The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J Pain 2005, 6(3):159-167. 10.1016/j.jpain.2004.11.008, 15772909.
    • (2005) J Pain , vol.6 , Issue.3 , pp. 159-167
    • Fillingim, R.B.1    Kaplan, L.2    Staud, R.3    Ness, T.J.4    Glover, T.L.5    Campbell, C.M.6
  • 13
    • 1642580560 scopus 로고    scopus 로고
    • Acute pain after endoscopic totally extraperitoneal (TEP) inguinal hernioplasty: multivariate analysis of predictive factors
    • 10.1007/s00464-003-9068-y, 14625741
    • Lau H, Patil NG. Acute pain after endoscopic totally extraperitoneal (TEP) inguinal hernioplasty: multivariate analysis of predictive factors. Surg Endosc 2004, 18(1):92-96. 10.1007/s00464-003-9068-y, 14625741.
    • (2004) Surg Endosc , vol.18 , Issue.1 , pp. 92-96
    • Lau, H.1    Patil, N.G.2
  • 15
    • 70350620288 scopus 로고    scopus 로고
    • Meta-analysis of the relevance of the OPRM1 118A^gt;G genetic variant for pain treatment
    • Dec, 10.1016/j.pain.2009.07.013, 19683391
    • Walter C, Lotsch J. Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment. Pain 2009, 146(3):270-275. Dec, 10.1016/j.pain.2009.07.013, 19683391.
    • (2009) Pain , vol.146 , Issue.3 , pp. 270-275
    • Walter, C.1    Lotsch, J.2
  • 16
    • 2442420245 scopus 로고    scopus 로고
    • Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament
    • 10.1016/j.pain.2004.02.027, 15157710
    • Kim H, Neubert JK, San Miguel A, Xu K, Krishnaraju RK, Iadarola MJ. Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament. Pain 2004, 109(3):488-496. 10.1016/j.pain.2004.02.027, 15157710.
    • (2004) Pain , vol.109 , Issue.3 , pp. 488-496
    • Kim, H.1    Neubert, J.K.2    San Miguel, A.3    Xu, K.4    Krishnaraju, R.K.5    Iadarola, M.J.6
  • 17
    • 33846269106 scopus 로고    scopus 로고
    • Genetic predictors for acute experimental cold and heat pain sensitivity in humans
    • 10.1136/jmg.2005.036079, 2564596, 16882734
    • Kim H, Mittal DP, Iadarola MJ, Dionne RA. Genetic predictors for acute experimental cold and heat pain sensitivity in humans. J Med Genet 2006, 43(8):e40. 10.1136/jmg.2005.036079, 2564596, 16882734.
    • (2006) J Med Genet , vol.43 , Issue.8
    • Kim, H.1    Mittal, D.P.2    Iadarola, M.J.3    Dionne, R.A.4
  • 18
    • 0034975213 scopus 로고    scopus 로고
    • Quantitative trait loci influencing morphine antinociception in four mapping populations
    • 10.1007/s003350020022, 11420618
    • Bergeson SE, Helms ML, O'Toole LA, Jarvis MW, Hain HS, Mogil JS. Quantitative trait loci influencing morphine antinociception in four mapping populations. Mamm Genome 2001, 12(7):546-553. 10.1007/s003350020022, 11420618.
    • (2001) Mamm Genome , vol.12 , Issue.7 , pp. 546-553
    • Bergeson, S.E.1    Helms, M.L.2    O'Toole, L.A.3    Jarvis, M.W.4    Hain, H.S.5    Mogil, J.S.6
  • 19
    • 12244277378 scopus 로고    scopus 로고
    • Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones
    • 10.1046/j.1460-9568.2003.02482.x, 12603260
    • Martin M, Matifas A, Maldonado R, Kieffer BL. Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones. Eur J Neurosci 2003, 17(4):701-708. 10.1046/j.1460-9568.2003.02482.x, 12603260.
    • (2003) Eur J Neurosci , vol.17 , Issue.4 , pp. 701-708
    • Martin, M.1    Matifas, A.2    Maldonado, R.3    Kieffer, B.L.4
  • 20
    • 0036551766 scopus 로고    scopus 로고
    • Opioid receptor genes inactivated in mice: the highlights
    • Gaveriaux-Ruff C, Kieffer BL. Opioid receptor genes inactivated in mice: the highlights. Neuropeptides 2002, 36(2-3):62-71.
    • (2002) Neuropeptides , vol.36 , Issue.2-3 , pp. 62-71
    • Gaveriaux-Ruff, C.1    Kieffer, B.L.2
  • 21
    • 33644958079 scopus 로고    scopus 로고
    • Neuropathic pain is enhanced in delta-opioid receptor knockout mice
    • 10.1111/j.1460-9568.2006.04569.x, 16487163
    • Nadal X, Banos JE, Kieffer BL, Maldonado R. Neuropathic pain is enhanced in delta-opioid receptor knockout mice. Eur J Neurosci 2006, 23(3):830-834. 10.1111/j.1460-9568.2006.04569.x, 16487163.
    • (2006) Eur J Neurosci , vol.23 , Issue.3 , pp. 830-834
    • Nadal, X.1    Banos, J.E.2    Kieffer, B.L.3    Maldonado, R.4
  • 22
    • 0032481350 scopus 로고    scopus 로고
    • Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal
    • 10.1093/emboj/17.4.886, 1170438, 9463367
    • Simonin F, Valverde O, Smadja C, Slowe S, Kitchen I, Dierich A. Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal. EMBO J 1998, 17(4):886-897. 10.1093/emboj/17.4.886, 1170438, 9463367.
    • (1998) EMBO J , vol.17 , Issue.4 , pp. 886-897
    • Simonin, F.1    Valverde, O.2    Smadja, C.3    Slowe, S.4    Kitchen, I.5    Dierich, A.6
  • 23
    • 21144431897 scopus 로고    scopus 로고
    • Diversifying the repertoire of G protein-coupled receptors through oligomerization
    • 10.1073/pnas.0504016102, 1157063, 15956197
    • Park PS, Palczewski K. Diversifying the repertoire of G protein-coupled receptors through oligomerization. Proc Natl Acad Sci USA 2005, 102(25):8793-8794. 10.1073/pnas.0504016102, 1157063, 15956197.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.25 , pp. 8793-8794
    • Park, P.S.1    Palczewski, K.2
  • 24
    • 1842687121 scopus 로고    scopus 로고
    • A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia
    • 10.1073/pnas.0307601101, 387386, 15044695
    • Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, Devi LA. A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proc Natl Acad Sci USA 2004, 101(14):5135-5139. 10.1073/pnas.0307601101, 387386, 15044695.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.14 , pp. 5135-5139
    • Gomes, I.1    Gupta, A.2    Filipovska, J.3    Szeto, H.H.4    Pintar, J.E.5    Devi, L.A.6
  • 26
    • 0742288585 scopus 로고    scopus 로고
    • The complex interplay among factors that influence allelic association
    • Zondervan KT, Cardon LR. The complex interplay among factors that influence allelic association. Nat Rev Genet 2004, 5(2):89-100.
    • (2004) Nat Rev Genet , vol.5 , Issue.2 , pp. 89-100
    • Zondervan, K.T.1    Cardon, L.R.2
  • 27
    • 18844451788 scopus 로고    scopus 로고
    • Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm
    • 10.1016/j.neuroscience.2004.12.033, 15893644
    • Pan L, Xu J, Yu R, Xu MM, Pan YX, Pasternak GW. Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm. Neuroscience 2005, 133(1):209-220. 10.1016/j.neuroscience.2004.12.033, 15893644.
    • (2005) Neuroscience , vol.133 , Issue.1 , pp. 209-220
    • Pan, L.1    Xu, J.2    Yu, R.3    Xu, M.M.4    Pan, Y.X.5    Pasternak, G.W.6
  • 28
    • 28444479463 scopus 로고    scopus 로고
    • Diversity and complexity of the mu opioid receptor gene: alternative pre-mRNA splicing and promoters
    • 10.1089/dna.2005.24.736, 16274294
    • Pan YX. Diversity and complexity of the mu opioid receptor gene: alternative pre-mRNA splicing and promoters. DNA Cell Biol 2005, 24(11):736-750. 10.1089/dna.2005.24.736, 16274294.
    • (2005) DNA Cell Biol , vol.24 , Issue.11 , pp. 736-750
    • Pan, Y.X.1
  • 29
    • 61849086376 scopus 로고    scopus 로고
    • Expansion of the Human {micro}-Opioid Receptor Gene Architecture: Novel Functional Variants
    • Mar 15, 10.1093/hmg/ddn439, 2649019, 19103668
    • Shabalina SA, Zaykin DV, Gris P, Ogurtsov AY, Gauthier J, Shibata K. Expansion of the Human {micro}-Opioid Receptor Gene Architecture: Novel Functional Variants. Hum Mol Genet 2009, 18(6):1037-1051. Mar 15, 10.1093/hmg/ddn439, 2649019, 19103668.
    • (2009) Hum Mol Genet , vol.18 , Issue.6 , pp. 1037-1051
    • Shabalina, S.A.1    Zaykin, D.V.2    Gris, P.3    Ogurtsov, A.Y.4    Gauthier, J.5    Shibata, K.6
  • 30
    • 0342617499 scopus 로고    scopus 로고
    • Detection of opioid receptor mRNA by RT-PCR reveals alternative splicing for the delta- and kappa-opioid receptors
    • 10.1016/S0169-328X(97)00109-5, 9332727
    • Gaveriaux-Ruff C, Peluso J, Befort K, Simonin F, Zilliox C, Kieffer BL. Detection of opioid receptor mRNA by RT-PCR reveals alternative splicing for the delta- and kappa-opioid receptors. Brain Res Mol Brain Res 1997, 48(2):298-304. 10.1016/S0169-328X(97)00109-5, 9332727.
    • (1997) Brain Res Mol Brain Res , vol.48 , Issue.2 , pp. 298-304
    • Gaveriaux-Ruff, C.1    Peluso, J.2    Befort, K.3    Simonin, F.4    Zilliox, C.5    Kieffer, B.L.6
  • 31
  • 32
    • 4444293506 scopus 로고    scopus 로고
    • Differences between male and female responses to painful thermal and mechanical stimulation of the human esophagus
    • Pedersen J, Reddy H, Funch-Jensen P, Arendt-Nielsen L, Gregersen H, Drewes AM. Differences between male and female responses to painful thermal and mechanical stimulation of the human esophagus. Dig Dis Sci 2004, 49(7-8):1065-1074.
    • (2004) Dig Dis Sci , vol.49 , Issue.7-8 , pp. 1065-1074
    • Pedersen, J.1    Reddy, H.2    Funch-Jensen, P.3    Arendt-Nielsen, L.4    Gregersen, H.5    Drewes, A.M.6
  • 33
    • 65349116535 scopus 로고    scopus 로고
    • Sex, gender, and pain: a review of recent clinical and experimental findings
    • 10.1016/j.jpain.2008.12.001, 2677686, 19411059
    • Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL. Sex, gender, and pain: a review of recent clinical and experimental findings. J Pain 2009, 10(5):447-485. 10.1016/j.jpain.2008.12.001, 2677686, 19411059.
    • (2009) J Pain , vol.10 , Issue.5 , pp. 447-485
    • Fillingim, R.B.1    King, C.D.2    Ribeiro-Dasilva, M.C.3    Rahim-Williams, B.4    Riley, J.L.5
  • 34
    • 69549103237 scopus 로고    scopus 로고
    • Predictors of postoperative pain and analgesic consumption: a qualitative systematic review
    • 10.1097/ALN.0b013e3181aae87a, 19672167
    • Ip HY, Abrishami A, Peng PW, Wong J, Chung F. Predictors of postoperative pain and analgesic consumption: a qualitative systematic review. Anesthesiology 2009, 111(3):657-677. 10.1097/ALN.0b013e3181aae87a, 19672167.
    • (2009) Anesthesiology , vol.111 , Issue.3 , pp. 657-677
    • Ip, H.Y.1    Abrishami, A.2    Peng, P.W.3    Wong, J.4    Chung, F.5
  • 35
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • 10.1016/S0301-0082(02)00009-6, 12034378
    • Millan MJ. Descending control of pain. Prog Neurobiol 2002, 66(6):355-474. 10.1016/S0301-0082(02)00009-6, 12034378.
    • (2002) Prog Neurobiol , vol.66 , Issue.6 , pp. 355-474
    • Millan, M.J.1
  • 36
    • 70349663909 scopus 로고    scopus 로고
    • Personality differences affect brainstem autonomic responses to visceral pain
    • 10.1111/j.1365-2982.2009.01348.x, 19538443
    • Paine P, Worthen SF, Gregory LJ, Thompson DG, Aziz Q. Personality differences affect brainstem autonomic responses to visceral pain. Neurogastroenterol Motil 2009, 21(11):1155-e1198. 10.1111/j.1365-2982.2009.01348.x, 19538443.
    • (2009) Neurogastroenterol Motil , vol.21 , Issue.11
    • Paine, P.1    Worthen, S.F.2    Gregory, L.J.3    Thompson, D.G.4    Aziz, Q.5
  • 37
    • 67649506557 scopus 로고    scopus 로고
    • Exploring relationships for visceral and somatic pain with autonomic control and personality
    • 10.1016/j.pain.2009.02.022, 19398272
    • Paine P, Kishor J, Worthen SF, Gregory LJ, Aziz Q. Exploring relationships for visceral and somatic pain with autonomic control and personality. Pain 2009, 144(3):236-244. 10.1016/j.pain.2009.02.022, 19398272.
    • (2009) Pain , vol.144 , Issue.3 , pp. 236-244
    • Paine, P.1    Kishor, J.2    Worthen, S.F.3    Gregory, L.J.4    Aziz, Q.5
  • 38
    • 80052133368 scopus 로고    scopus 로고
    • Neuroticism influences brain activity during the experience of visceral pain
    • 10.1053/j.gastro.2011.06.008, 21699797
    • Coen SJ, Kano M, Farmer AD, Kumari V, Giampietro V, Brammer M. Neuroticism influences brain activity during the experience of visceral pain. Gastroenterology 2011, 141(3):909-917. 10.1053/j.gastro.2011.06.008, 21699797.
    • (2011) Gastroenterology , vol.141 , Issue.3 , pp. 909-917
    • Coen, S.J.1    Kano, M.2    Farmer, A.D.3    Kumari, V.4    Giampietro, V.5    Brammer, M.6
  • 39
    • 79952450991 scopus 로고    scopus 로고
    • Which variables are associated with pain intensity and treatment response in advanced cancer patients? - Implications for a future classification system for cancer pain
    • Mar, 10.1016/j.ejpain.2010.08.001, 20822941
    • Knudsen AK, Brunelli C, Kaasa S, Apolone G, Corli O, Montanari M. Which variables are associated with pain intensity and treatment response in advanced cancer patients? - Implications for a future classification system for cancer pain. Eur J Pain 2011, 15(3):320-327. Mar, 10.1016/j.ejpain.2010.08.001, 20822941.
    • (2011) Eur J Pain , vol.15 , Issue.3 , pp. 320-327
    • Knudsen, A.K.1    Brunelli, C.2    Kaasa, S.3    Apolone, G.4    Corli, O.5    Montanari, M.6
  • 40
    • 0018687264 scopus 로고
    • Baroreceptor activation reduces reactivity to noxious stimulation: implications for hypertension
    • 10.1126/science.472749, 472749
    • Dworkin BR, Filewich RJ, Miller NE, Craigmyle N, Pickering TG. Baroreceptor activation reduces reactivity to noxious stimulation: implications for hypertension. Science 1979, 205(4412):1299-1301. 10.1126/science.472749, 472749.
    • (1979) Science , vol.205 , Issue.4412 , pp. 1299-1301
    • Dworkin, B.R.1    Filewich, R.J.2    Miller, N.E.3    Craigmyle, N.4    Pickering, T.G.5
  • 41
    • 79954571603 scopus 로고    scopus 로고
    • Factor analysis of responses to thermal, electrical, and mechanical painful stimuli supports the importance of multi-modal pain assessment
    • 10.1016/j.pain.2011.01.047, 21396782
    • Neziri AY, Curatolo M, Nuesch E, Scaramozzino P, Andersen OK, Arendt-Nielsen L. Factor analysis of responses to thermal, electrical, and mechanical painful stimuli supports the importance of multi-modal pain assessment. Pain 2011, 152(5):1146-1155. 10.1016/j.pain.2011.01.047, 21396782.
    • (2011) Pain , vol.152 , Issue.5 , pp. 1146-1155
    • Neziri, A.Y.1    Curatolo, M.2    Nuesch, E.3    Scaramozzino, P.4    Andersen, O.K.5    Arendt-Nielsen, L.6
  • 42
    • 2342459714 scopus 로고    scopus 로고
    • Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
    • 10.1200/JCO.2004.07.173, 15007088
    • Innocenti F, Undevia SD, Iyer L, Chen PX, Das S, Kocherginsky M. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 2004, 22(8):1382-1388. 10.1200/JCO.2004.07.173, 15007088.
    • (2004) J Clin Oncol , vol.22 , Issue.8 , pp. 1382-1388
    • Innocenti, F.1    Undevia, S.D.2    Iyer, L.3    Chen, P.X.4    Das, S.5    Kocherginsky, M.6
  • 43
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • 10.1126/science.1109557, 1512523, 15761122
    • Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C. Complement factor H polymorphism in age-related macular degeneration. Science 2005, 308(5720):385-389. 10.1126/science.1109557, 1512523, 15761122.
    • (2005) Science , vol.308 , Issue.5720 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3    Tsai, J.Y.4    Sackler, R.S.5    Haynes, C.6
  • 44
    • 33751011889 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism in wet age-related macular degeneration
    • 10.1126/science.1133807, 17053108
    • Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C. HTRA1 promoter polymorphism in wet age-related macular degeneration. Science 2006, 314(5801):989-992. 10.1126/science.1133807, 17053108.
    • (2006) Science , vol.314 , Issue.5801 , pp. 989-992
    • Dewan, A.1    Liu, M.2    Hartman, S.3    Zhang, S.S.4    Liu, D.T.5    Zhao, C.6
  • 45
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn JN, Daly MJ. Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 2005, 6(2):95-108.
    • (2005) Nat Rev Genet , vol.6 , Issue.2 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 46
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: theoretical and practical concerns
    • 10.1038/nrg1522, 15716907
    • Wang WY, Barratt BJ, Clayton DG, Todd JA. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 2005, 6(2):109-118. 10.1038/nrg1522, 15716907.
    • (2005) Nat Rev Genet , vol.6 , Issue.2 , pp. 109-118
    • Wang, W.Y.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 47
    • 77954505370 scopus 로고    scopus 로고
    • Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study
    • 10.1111/j.1365-2125.2010.03700.x, 2911549, 20653672
    • Olesen AE, Staahl C, rendt-Nielsen L, Drewes AM. Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study. Br J Clin Pharmacol 2010, 70(2):189-200. 10.1111/j.1365-2125.2010.03700.x, 2911549, 20653672.
    • (2010) Br J Clin Pharmacol , vol.70 , Issue.2 , pp. 189-200
    • Olesen, A.E.1    Staahl, C.2    rendt-Nielsen, L.3    Drewes, A.M.4
  • 48
    • 33947331049 scopus 로고    scopus 로고
    • Human experimental pain models in drug development: translational pain research
    • Arendt-Nielsen L, Curatolo M, Drewes A. Human experimental pain models in drug development: translational pain research. Curr Opin Investig Drugs 2007, 8(1):41-53.
    • (2007) Curr Opin Investig Drugs , vol.8 , Issue.1 , pp. 41-53
    • Arendt-Nielsen, L.1    Curatolo, M.2    Drewes, A.3
  • 49
    • 33744511725 scopus 로고    scopus 로고
    • A comparative study of oxycodone and morphine in a multi-modal, tissue-differentiated experimental pain model
    • Staahl C, Christrup LL, Andersen SD, Arendt-Nielsen L, Drewes AM. A comparative study of oxycodone and morphine in a multi-modal, tissue-differentiated experimental pain model. Pain 2006, 123(1-2):28-36.
    • (2006) Pain , vol.123 , Issue.1-2 , pp. 28-36
    • Staahl, C.1    Christrup, L.L.2    Andersen, S.D.3    Arendt-Nielsen, L.4    Drewes, A.M.5
  • 50
    • 69549122425 scopus 로고    scopus 로고
    • Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain
    • 10.1097/ALN.0b013e3181af6356, 19672186
    • Arendt-Nielsen L, Olesen AE, Staahl C, Menzaghi F, Kell S, Wong GY. Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain. Anesthesiology 2009, 111(3):616-624. 10.1097/ALN.0b013e3181af6356, 19672186.
    • (2009) Anesthesiology , vol.111 , Issue.3 , pp. 616-624
    • Arendt-Nielsen, L.1    Olesen, A.E.2    Staahl, C.3    Menzaghi, F.4    Kell, S.5    Wong, G.Y.6
  • 51
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • 10.1086/319501, 1275651, 11254454
    • Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001, 68(4):978-989. 10.1086/319501, 1275651, 11254454.
    • (2001) Am J Hum Genet , vol.68 , Issue.4 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 52
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • 10.1093/bioinformatics/bth457, 15297300
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21(2):263-265. 10.1093/bioinformatics/bth457, 15297300.
    • (2005) Bioinformatics , vol.21 , Issue.2 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 53
    • 7444257916 scopus 로고    scopus 로고
    • Genetics, statistics and human disease: analytical retooling for complexity
    • 10.1016/j.tig.2004.09.007, 15522460
    • Thornton-Wells TA, Moore JH, Haines JL. Genetics, statistics and human disease: analytical retooling for complexity. Trends Genet 2004, 20(12):640-647. 10.1016/j.tig.2004.09.007, 15522460.
    • (2004) Trends Genet , vol.20 , Issue.12 , pp. 640-647
    • Thornton-Wells, T.A.1    Moore, J.H.2    Haines, J.L.3


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