-
1
-
-
49649093757
-
Role of endocrine-genotoxic switchings in cancer and other human diseases: basic triad
-
Bernstein L.M. Role of endocrine-genotoxic switchings in cancer and other human diseases: basic triad. Adv Exp Med Biol 2008, 630:35-51.
-
(2008)
Adv Exp Med Biol
, vol.630
, pp. 35-51
-
-
Bernstein, L.M.1
-
2
-
-
34249699540
-
Non-alcoholic steatohepatitis and cancer
-
Bugianesi E. Non-alcoholic steatohepatitis and cancer. Clin Liver Dis 2007, 11:191-207.
-
(2007)
Clin Liver Dis
, vol.11
, pp. 191-207
-
-
Bugianesi, E.1
-
3
-
-
66749091560
-
Role of nonalcoholic fatty liver disease in hepatocellular carcinoma
-
Chávez-Tapia N.C., Méndez-Sánchez N., Uribe M. Role of nonalcoholic fatty liver disease in hepatocellular carcinoma. Ann Hepatol 2009, 8:S34-S39.
-
(2009)
Ann Hepatol
, vol.8
-
-
Chávez-Tapia, N.C.1
Méndez-Sánchez, N.2
Uribe, M.3
-
4
-
-
33750617327
-
Oncongene-specific gene expression signatures at preneoplastic state in mice define distinct mechanisms of hepatocarcinogenesis
-
Coulouarn C., Gomez-Quiroz L.E., Lee J.S., Kaposi-Novak P., Conner E.A., Goldina T.A., et al. Oncongene-specific gene expression signatures at preneoplastic state in mice define distinct mechanisms of hepatocarcinogenesis. Hepatology 2006, 44:1003-1011.
-
(2006)
Hepatology
, vol.44
, pp. 1003-1011
-
-
Coulouarn, C.1
Gomez-Quiroz, L.E.2
Lee, J.S.3
Kaposi-Novak, P.4
Conner, E.A.5
Goldina, T.A.6
-
5
-
-
84875895935
-
Lessons from animal models
-
Diehl A.M. Lessons from animal models. Hepatol Res 2005, 33:137-144.
-
(2005)
Hepatol Res
, vol.33
, pp. 137-144
-
-
Diehl, A.M.1
-
6
-
-
33745570822
-
Southern Europe as an example of interaction between various environmental factors: a systematic review of the epidemiologic evidence
-
Donato F., Gelatti U., Limina R.M., Fattovich G. Southern Europe as an example of interaction between various environmental factors: a systematic review of the epidemiologic evidence. Oncogene 2006, 25:3756-3770.
-
(2006)
Oncogene
, vol.25
, pp. 3756-3770
-
-
Donato, F.1
Gelatti, U.2
Limina, R.M.3
Fattovich, G.4
-
7
-
-
0009663357
-
A multiple comparison procedure for comparing several treatments with a control
-
Dunnett C.W. A multiple comparison procedure for comparing several treatments with a control. J Am Stat Assoc 1955, 50:1096-1121.
-
(1955)
J Am Stat Assoc
, vol.50
, pp. 1096-1121
-
-
Dunnett, C.W.1
-
8
-
-
0348134733
-
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice
-
Feldstein A.E., Canbay A., Guicciardi M.E., Higuchi H., Bronk S.F., Gores G.J. Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. J Hepatol 2003, 39:978-983.
-
(2003)
J Hepatol
, vol.39
, pp. 978-983
-
-
Feldstein, A.E.1
Canbay, A.2
Guicciardi, M.E.3
Higuchi, H.4
Bronk, S.F.5
Gores, G.J.6
-
9
-
-
0019949179
-
Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide
-
Fossati P., Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 1982, 28(10):2077-2080.
-
(1982)
Clin Chem
, vol.28
, Issue.10
, pp. 2077-2080
-
-
Fossati, P.1
Prencipe, L.2
-
10
-
-
0020771382
-
Spontaneous lesions in virgin and retired breeder BALB/c and C57BL/6 mice
-
Frith C.H., Highman B., Burger G., Sheldon W.D. Spontaneous lesions in virgin and retired breeder BALB/c and C57BL/6 mice. Lab Anim Sci 1983, 33:273-286.
-
(1983)
Lab Anim Sci
, vol.33
, pp. 273-286
-
-
Frith, C.H.1
Highman, B.2
Burger, G.3
Sheldon, W.D.4
-
11
-
-
33846473612
-
Nonalcoholic fatty liver disease in severely obese subjects
-
Gholam P.M., Flancbaum L., Machan J.T., Charney D.A., Kotler D.P. Nonalcoholic fatty liver disease in severely obese subjects. Am J Gastroenterol 2007, 102:399-408.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 399-408
-
-
Gholam, P.M.1
Flancbaum, L.2
Machan, J.T.3
Charney, D.A.4
Kotler, D.P.5
-
12
-
-
0020334611
-
32P-postlabeling analysis of non-radioactive aromatic carcinogen - DNA adducts
-
32P-postlabeling analysis of non-radioactive aromatic carcinogen - DNA adducts. Carcinogenesis 1982, 3:1081-1092.
-
(1982)
Carcinogenesis
, vol.3
, pp. 1081-1092
-
-
Gupta, R.C.1
Reddy, M.V.2
Randerath, K.3
-
13
-
-
68049107481
-
Diet-inducted hepatocellular carcinoma in genetically predisposed mice
-
Hill-Baskin A.E., Markiewski M.M., Buchner D.A., Shao H., DeSantis D., Hsiao G., et al. Diet-inducted hepatocellular carcinoma in genetically predisposed mice. Hum Mol Genet 2009, 18(16):2975-2988.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.16
, pp. 2975-2988
-
-
Hill-Baskin, A.E.1
Markiewski, M.M.2
Buchner, D.A.3
Shao, H.4
DeSantis, D.5
Hsiao, G.6
-
15
-
-
39749173966
-
Metabolic syndrome is related to nonalcoholic steatohepatitis in severely obese subjects
-
Huang H.L., Lin W.Y., Lee L.T., Wang H.H., Lee W.J., Huang K.C. Metabolic syndrome is related to nonalcoholic steatohepatitis in severely obese subjects. Obes Surg 2007, 17:1457-1463.
-
(2007)
Obes Surg
, vol.17
, pp. 1457-1463
-
-
Huang, H.L.1
Lin, W.Y.2
Lee, L.T.3
Wang, H.H.4
Lee, W.J.5
Huang, K.C.6
-
17
-
-
0036170952
-
Lack of DNA binding on the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline
-
Jeffrey A.M., Luo FlQ, Amin S., Krzeminski J., Zech K., Williams G.M. Lack of DNA binding on the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline. Drug Chem Toxicol 2002, 25:93-107.
-
(2002)
Drug Chem Toxicol
, vol.25
, pp. 93-107
-
-
Jeffrey, A.M.1
Luo, F.Q.2
Amin, S.3
Krzeminski, J.4
Zech, K.5
Williams, G.M.6
-
18
-
-
56649083495
-
Mechanisms of disease progression in nonalcoholic fatty liver disease
-
Jou J., Choi S.S., Diehl A.M. Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin Liver Dis 2008, 28:370-379.
-
(2008)
Semin Liver Dis
, vol.28
, pp. 370-379
-
-
Jou, J.1
Choi, S.S.2
Diehl, A.M.3
-
20
-
-
20344387386
-
Comparative functional genomics for identifying model of human cancer
-
Lee J.S., Grisham J.W., Thorgeirsson S.S. Comparative functional genomics for identifying model of human cancer. Carcinogenesis 2005, 26:1013-1020.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1013-1020
-
-
Lee, J.S.1
Grisham, J.W.2
Thorgeirsson, S.S.3
-
21
-
-
0037428819
-
Antitumour 2-(4-aminophenyl)benzothiasoles generate DNA adducts in sensitive tumour cells in vitro and in vivo
-
Leong C.O., Gaskell M., Martin E.A., Heydon R.T., Farmer P.B., Bibby M.C., et al. Antitumour 2-(4-aminophenyl)benzothiasoles generate DNA adducts in sensitive tumour cells in vitro and in vivo. Br J Cancer 2003, 88:470-477.
-
(2003)
Br J Cancer
, vol.88
, pp. 470-477
-
-
Leong, C.O.1
Gaskell, M.2
Martin, E.A.3
Heydon, R.T.4
Farmer, P.B.5
Bibby, M.C.6
-
22
-
-
33846839443
-
Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
Luedde T., Beraza N., Kotsikoris V., van Loo G., Nenci A., De Vos R., et al. Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 2007, 11:119-132.
-
(2007)
Cancer Cell
, vol.11
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
van Loo, G.4
Nenci, A.5
De Vos, R.6
-
23
-
-
34547993608
-
Nonalcoholic fatty pancreas disease
-
Mathur A., Marine M., Lu D., Swartz-Basile D.A., Saxena R., Zyromski N.J. Nonalcoholic fatty pancreas disease. HPB 2007, 9:312-318.
-
(2007)
HPB
, vol.9
, pp. 312-318
-
-
Mathur, A.1
Marine, M.2
Lu, D.3
Swartz-Basile, D.A.4
Saxena, R.5
Zyromski, N.J.6
-
24
-
-
29244444549
-
Nonalcoholic steatohepatitis and the metabolic syndrome
-
Neuschwander-Tetri B.A. Nonalcoholic steatohepatitis and the metabolic syndrome. Am J Med Sci 2005, 330:326-335.
-
(2005)
Am J Med Sci
, vol.330
, pp. 326-335
-
-
Neuschwander-Tetri, B.A.1
-
25
-
-
54949115804
-
The effect of fasting on hepatic lipid accumulation and transcriptional regulation of lipid metabolism differs between C57BL/6J and BALB/cA mice fed a high-fat diet
-
Nishikawa S., Doi K., Nakayama H., Uetsuka K. The effect of fasting on hepatic lipid accumulation and transcriptional regulation of lipid metabolism differs between C57BL/6J and BALB/cA mice fed a high-fat diet. Toxicol Pathol 2008, 36:850-857.
-
(2008)
Toxicol Pathol
, vol.36
, pp. 850-857
-
-
Nishikawa, S.1
Doi, K.2
Nakayama, H.3
Uetsuka, K.4
-
26
-
-
34249729341
-
Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns
-
Otu H.H., Naxerova K., Ho K., Nesbitt N., Libermann T.A., Karp S.J. Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns. J Biol Chem 2007, 282:11197-11204.
-
(2007)
J Biol Chem
, vol.282
, pp. 11197-11204
-
-
Otu, H.H.1
Naxerova, K.2
Ho, K.3
Nesbitt, N.4
Libermann, T.A.5
Karp, S.J.6
-
27
-
-
33746268320
-
Molecular pathways in hepatocellular carcinoma
-
Pang R., Tse E., Poon R.T. Molecular pathways in hepatocellular carcinoma. Cancer Lett 2006, 240:157-169.
-
(2006)
Cancer Lett
, vol.240
, pp. 157-169
-
-
Pang, R.1
Tse, E.2
Poon, R.T.3
-
28
-
-
33646413672
-
The global health burden of infection-associated cancers in the year 2002
-
Parkin D.M. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006, 118:3030-3044.
-
(2006)
Int J Cancer
, vol.118
, pp. 3030-3044
-
-
Parkin, D.M.1
-
29
-
-
0032892630
-
Standardization and validation of DNA adduct postlabeling methods: report of interlaboratory trials and production of recommended protocols
-
Phillips D.H., Castegnaro M. Standardization and validation of DNA adduct postlabeling methods: report of interlaboratory trials and production of recommended protocols. Mutagenesis 1999, 14:301-315.
-
(1999)
Mutagenesis
, vol.14
, pp. 301-315
-
-
Phillips, D.H.1
Castegnaro, M.2
-
31
-
-
0022774562
-
32P-postlabeling test for structurally diverse DNA adducts
-
32P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis 1986, 7:1543-1551.
-
(1986)
Carcinogenesis
, vol.7
, pp. 1543-1551
-
-
Reddy, M.Y.1
Randerath, K.2
-
32
-
-
33747356154
-
Adipose tissue: from lipid storage compartment to endocrine organ
-
Scherer P.E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 2006, 55:1537-1545.
-
(2006)
Diabetes
, vol.55
, pp. 1537-1545
-
-
Scherer, P.E.1
-
33
-
-
37349053667
-
Identification of specific DNA-adduct patterns in organic chemical structures in outdoor air [in German]
-
Available at: [accessed 15.06.08].
-
Schmeiser HH, Bieler C., Wiessler M, Fried M, Erdinger L. Identification of specific DNA-adduct patterns in organic chemical structures in outdoor air [in German]; 1999. Available at: [accessed 15.06.08]. http://bwplus.fzk.de/berichte/ZberL96011.pdf.
-
(1999)
-
-
Schmeiser, H.H.1
Bieler, C..2
Wiessler, M.3
Fried, M.4
Erdinger, L.5
-
34
-
-
67650938576
-
Hepatocellular carcinoma-epidemiological trends and risk factors
-
Schütte K., Bornschein J., Malfertheiner P. Hepatocellular carcinoma-epidemiological trends and risk factors. Digest Dis 2009, 27:80-92.
-
(2009)
Digest Dis
, vol.27
, pp. 80-92
-
-
Schütte, K.1
Bornschein, J.2
Malfertheiner, P.3
-
35
-
-
84875886647
-
Predisposition of diet-induced obese C57BL/6J mice to liver and lung neoplasms
-
Stedman N.L., Hayes A.N., Leach M.W. Predisposition of diet-induced obese C57BL/6J mice to liver and lung neoplasms. Vet Pathol 2009, 46(5):1060.
-
(2009)
Vet Pathol
, vol.46
, Issue.5
, pp. 1060
-
-
Stedman, N.L.1
Hayes, A.N.2
Leach, M.W.3
-
36
-
-
0042150359
-
Diet-induced obesity and diabetes in C57BL/6J and C57BL/KsJ mice
-
Surwit R.S., Seldin M.F., Kuhn C.M., Secor C., Feinglos M.N. Diet-induced obesity and diabetes in C57BL/6J and C57BL/KsJ mice. Mouse Genome 1994, 92:523-525.
-
(1994)
Mouse Genome
, vol.92
, pp. 523-525
-
-
Surwit, R.S.1
Seldin, M.F.2
Kuhn, C.M.3
Secor, C.4
Feinglos, M.N.5
-
37
-
-
0029065480
-
Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice
-
Surwit R.S., Feinglos M.N., Rodin J., Sutherland A., Petro A.E., Opara E.C., et al. Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 1995, 44:645-651.
-
(1995)
Metabolism
, vol.44
, pp. 645-651
-
-
Surwit, R.S.1
Feinglos, M.N.2
Rodin, J.3
Sutherland, A.4
Petro, A.E.5
Opara, E.C.6
-
38
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit R.S., Kuhn C.M., Cochrane C., McCubbin J.A., Feinglos M.N. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 1998, 37:1163-1167.
-
(1998)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
39
-
-
84875877126
-
-
Systat Software Inc.
-
Systat Software Inc.; 2004.
-
(2004)
-
-
-
40
-
-
38849184816
-
PPAR alpha activation is essential for HCV core protein induced hepatic steatosis and hepatocellular carcinoma in mice
-
Tanaka N., Moriya K., Kiyosawa K., Koike K., Gonzalez F.J., Aoyama T. PPAR alpha activation is essential for HCV core protein induced hepatic steatosis and hepatocellular carcinoma in mice. J Clin Invest 2008, 188:683-694.
-
(2008)
J Clin Invest
, vol.188
, pp. 683-694
-
-
Tanaka, N.1
Moriya, K.2
Kiyosawa, K.3
Koike, K.4
Gonzalez, F.J.5
Aoyama, T.6
-
41
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson S.S., Grisham J.W. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002, 31:339-346.
-
(2002)
Nat Genet
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
42
-
-
35548966020
-
Distinct pathways of genomic progression to benign and malignant tumors of the liver
-
Tward A.D., Jones K.D., Yant S., Cheung S.T., Fan S.T., Chen X., et al. Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci USA 2007, 104:14771-14776.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14771-14776
-
-
Tward, A.D.1
Jones, K.D.2
Yant, S.3
Cheung, S.T.4
Fan, S.T.5
Chen, X.6
-
43
-
-
0029746045
-
2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation
-
Verna L., Whysner J., Williams G.M. 2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation. Pharmacol Ther 1996, 71:83-105.
-
(1996)
Pharmacol Ther
, vol.71
, pp. 83-105
-
-
Verna, L.1
Whysner, J.2
Williams, G.M.3
-
44
-
-
58149316646
-
Nonalcoholic steatohepatitis induced by high-fat diet promotes diethylnitrosamine initiated early hepatocarcinogenesis in rats
-
Wang Y., Ausman L.M., Greenberg A.S., Russell R.M., Wang X.D. Nonalcoholic steatohepatitis induced by high-fat diet promotes diethylnitrosamine initiated early hepatocarcinogenesis in rats. Int J Cancer 2009, 124(3):540-546.
-
(2009)
Int J Cancer
, vol.124
, Issue.3
, pp. 540-546
-
-
Wang, Y.1
Ausman, L.M.2
Greenberg, A.S.3
Russell, R.M.4
Wang, X.D.5
-
45
-
-
84875883851
-
-
Website, [accessed March 2011].
-
Website, [accessed March 2011]. http://jaxmice.jax.org/diomice/diets.html.
-
-
-
-
46
-
-
85012852237
-
Chemicals with carcinogenic activity in rodent liver
-
Academic Press, Oxford
-
Williams G.M. Chemicals with carcinogenic activity in rodent liver. Comprehensive Toxicology 2010, vol. 9:221-250. Academic Press, Oxford.
-
(2010)
Comprehensive Toxicology
, vol.9
, pp. 221-250
-
-
Williams, G.M.1
-
47
-
-
0036186764
-
Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity
-
Williams G.M., Iatropoulos M.J. Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity. Toxicol Pathol 2002, 30:41-53.
-
(2002)
Toxicol Pathol
, vol.30
, pp. 41-53
-
-
Williams, G.M.1
Iatropoulos, M.J.2
-
48
-
-
0031769971
-
Non-linearities in 2-acetylaminofluorene exposure-responses for genotoxic and epigenetic effects leading to initiation of carcinogenesis in rat liver
-
Williams G.M., Iatropoulos M.J., Wang C.X., Jeffrey A.M., Thompson S., Pittman B., et al. Non-linearities in 2-acetylaminofluorene exposure-responses for genotoxic and epigenetic effects leading to initiation of carcinogenesis in rat liver. Toxicol Sci 1998, 45:152-161.
-
(1998)
Toxicol Sci
, vol.45
, pp. 152-161
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Wang, C.X.3
Jeffrey, A.M.4
Thompson, S.5
Pittman, B.6
-
49
-
-
3342962424
-
Thresholds for the effects of 2-acetylaminofluorene in rat liver
-
Williams G.M., Iatropoulos M.J., Jeffrey A.M. Thresholds for the effects of 2-acetylaminofluorene in rat liver. Toxicol Pathol 2004, 32(Suppl. 2):85-91.
-
(2004)
Toxicol Pathol
, vol.32
, Issue.SUPPL. 2
, pp. 85-91
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Jeffrey, A.M.3
-
51
-
-
4043094220
-
Retinoic acid receptor α dominant negative form causes steatohepatitis and liver tumors in transgenic mice
-
Yanagitani A., Yamada S., Yasui S., Shinomura T., Murai R., Murawaki Y., et al. Retinoic acid receptor α dominant negative form causes steatohepatitis and liver tumors in transgenic mice. Hepatology 2004, 40:366-375.
-
(2004)
Hepatology
, vol.40
, pp. 366-375
-
-
Yanagitani, A.1
Yamada, S.2
Yasui, S.3
Shinomura, T.4
Murai, R.5
Murawaki, Y.6
-
52
-
-
0035392939
-
Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?
-
Yang S., Lin H.Z., Hwang J., Chacko V.P., Diehl A.M. Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?. Cancer Res 2001, 61:5016-5023.
-
(2001)
Cancer Res
, vol.61
, pp. 5016-5023
-
-
Yang, S.1
Lin, H.Z.2
Hwang, J.3
Chacko, V.P.4
Diehl, A.M.5
|