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Volumn 1507, Issue , 2013, Pages 125-133

L-carnosine inhibits neuronal cell apoptosis through signal transducer and activator of transcription 3 signaling pathway after acute focal cerebral ischemia

Author keywords

Acute focal cerebral ischemia; l carnosine; Pim 1; STAT3

Indexed keywords

CARNOSINE; CASPASE 3; MESSENGER RNA; PROTEIN BCL 2; PROTEIN KINASE PIM 1; STAT3 PROTEIN;

EID: 84875872293     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.02.032     Document Type: Article
Times cited : (34)

References (27)
  • 1
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • J.B. Bederson, L.H. Pitts, M. Tsuji, M.C. Nishimura, R.L. Davis, and H. Bartkowski Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination Stroke 17 1986 472 476
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.6
  • 2
    • 0032833418 scopus 로고    scopus 로고
    • Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species
    • A. Boldyrev, R. Song, D. Lawrence, and D.O. Carpenter Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species Neuroscience 94 1999 571 577
    • (1999) Neuroscience , vol.94 , pp. 571-577
    • Boldyrev, A.1    Song, R.2    Lawrence, D.3    Carpenter, D.O.4
  • 5
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • J. Bromberg, and J.E. Darnell Jr. The role of STATs in transcriptional control and their impact on cellular function Oncogene 19 2000 2468 2473
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell Jr., J.E.2
  • 6
    • 67649506191 scopus 로고    scopus 로고
    • Tests to assess motor phenotype in mice: A user's guide
    • S.P. Brooks, and S.B. Dunnett Tests to assess motor phenotype in mice: a user's guide Nat. Rev. Neurosci. 10 2009 519 529
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 519-529
    • Brooks, S.P.1    Dunnett, S.B.2
  • 7
    • 84863874277 scopus 로고    scopus 로고
    • BCL-2 family of proteins and mammary cellular fate
    • M. Colitti BCL-2 family of proteins and mammary cellular fate Anat. Histol. Embryol. 41 2012 237 247
    • (2012) Anat. Histol. Embryol. , vol.41 , pp. 237-247
    • Colitti, M.1
  • 8
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • J.E. Darnell Jr. STATs and gene regulation Science 277 1997 1630 1635
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 9
    • 57649098421 scopus 로고    scopus 로고
    • Role of signal transducer and activator of transcription 3 in neuronal survival and regeneration
    • S. Dziennis, and N.J. Alkayed Role of signal transducer and activator of transcription 3 in neuronal survival and regeneration Rev. Neurosci. 19 2008 341 361
    • (2008) Rev. Neurosci. , vol.19 , pp. 341-361
    • Dziennis, S.1    Alkayed, N.J.2
  • 10
    • 67349163720 scopus 로고    scopus 로고
    • Inhibitory effect of carnosine and N-acetyl carnosine on LPS-induced microglial oxidative stress and inflammation
    • S. Fleisher-Berkovich, C. Abramovitch-Dahan, S. Ben-Shabat, R. Apte, and E. Beit-Yannai Inhibitory effect of carnosine and N-acetyl carnosine on LPS-induced microglial oxidative stress and inflammation Peptides 30 2009 1306 1312
    • (2009) Peptides , vol.30 , pp. 1306-1312
    • Fleisher-Berkovich, S.1    Abramovitch-Dahan, C.2    Ben-Shabat, S.3    Apte, R.4    Beit-Yannai, E.5
  • 12
    • 66149171367 scopus 로고    scopus 로고
    • Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia
    • J.E. Jung, G.S. Kim, P. Narasimhan, Y.S. Song, and P.H. Chan Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia J. Neurosci. 29 2009 7003 7014
    • (2009) J. Neurosci. , vol.29 , pp. 7003-7014
    • Jung, J.E.1    Kim, G.S.2    Narasimhan, P.3    Song, Y.S.4    Chan, P.H.5
  • 14
    • 79954459921 scopus 로고    scopus 로고
    • Regulation of mitochondrial metabolism: Yet another facet in the biology of the oncoprotein Bcl-2
    • S. Krishna, I.C. Low, and S. Pervaiz Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2 Biochem. J. 435 2011 545 551
    • (2011) Biochem. J. , vol.435 , pp. 545-551
    • Krishna, S.1    Low, I.C.2    Pervaiz, S.3
  • 15
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • D.E. Levy, and J.E. Darnell Jr. Stats: transcriptional control and biological impact Nat. Rev. Mol. Cell Biol. 3 2002 651 662
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 16
    • 62649101303 scopus 로고    scopus 로고
    • Effect of neuregulin on apoptosis and expressions of STAT3 and GFAP in rats following cerebral ischemic reperfusion
    • Q. Li, R. Zhang, Y.L. Guo, and Y.W. Mei Effect of neuregulin on apoptosis and expressions of STAT3 and GFAP in rats following cerebral ischemic reperfusion J. Mol. Neurosci. 37 2009 67 73
    • (2009) J. Mol. Neurosci. , vol.37 , pp. 67-73
    • Li, Q.1    Zhang, R.2    Guo, Y.L.3    Mei, Y.W.4
  • 17
    • 0033536203 scopus 로고    scopus 로고
    • The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway
    • M. Lilly, J. Sandholm, J.J. Cooper, P.J. Koskinen, and A. Kraft The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway Oncogene 18 1999 4022 4031
    • (1999) Oncogene , vol.18 , pp. 4022-4031
    • Lilly, M.1    Sandholm, J.2    Cooper, J.J.3    Koskinen, P.J.4    Kraft, A.5
  • 20
    • 0033451992 scopus 로고    scopus 로고
    • Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis
    • T. Shirogane, T. Fukada, J.M. Muller, D.T. Shima, M. Hibi, and T. Hirano Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis Immunity 11 1999 709 719
    • (1999) Immunity , vol.11 , pp. 709-719
    • Shirogane, T.1    Fukada, T.2    Muller, J.M.3    Shima, D.T.4    Hibi, M.5    Hirano, T.6
  • 21
    • 0027493650 scopus 로고
    • A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
    • K. Shuai, G.R. Stark, I.M. Kerr, and J.E. Darnell Jr. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma Science 261 1993 1744 1746
    • (1993) Science , vol.261 , pp. 1744-1746
    • Shuai, K.1    Stark, G.R.2    Kerr, I.M.3    Darnell Jr., J.E.4
  • 22
    • 38149072468 scopus 로고    scopus 로고
    • Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke
    • W.C. Shyu, S.Z. Lin, M.F. Chiang, D.C. Chen, C.Y. Su, H.J. Wang, R.S. Liu, C.H. Tsai, and H. Li Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke J. Clin. Invest. 118 2008 133 148
    • (2008) J. Clin. Invest. , vol.118 , pp. 133-148
    • Shyu, W.C.1    Lin, S.Z.2    Chiang, M.F.3    Chen, D.C.4    Su, C.Y.5    Wang, H.J.6    Liu, R.S.7    Tsai, C.H.8    Li, H.9
  • 23
    • 0034221295 scopus 로고    scopus 로고
    • Interactions between carnosine and zinc and copper: Implications for neuromodulation and neuroprotection
    • P.Q. Trombley, M.S. Horning, and L.J. Blakemore Interactions between carnosine and zinc and copper: implications for neuromodulation and neuroprotection Biochemistry (Mosc) 65 2000 807 816
    • (2000) Biochemistry (Mosc) , vol.65 , pp. 807-816
    • Trombley, P.Q.1    Horning, M.S.2    Blakemore, L.J.3
  • 25
    • 1842607295 scopus 로고    scopus 로고
    • Evaluation of murine models of permanent focal cerebral ischemia
    • G.M. Xi, H.Q. Wang, G.H. He, C.F. Huang, and G.Y. Wei Evaluation of murine models of permanent focal cerebral ischemia Chin. Med. J. (Engl) 117 2004 389 394
    • (2004) Chin. Med. J. (Engl) , vol.117 , pp. 389-394
    • Xi, G.M.1    Wang, H.Q.2    He, G.H.3    Huang, C.F.4    Wei, G.Y.5
  • 26
    • 22244468321 scopus 로고    scopus 로고
    • Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: Possible involvement of Stat3 activation in the protection of neurons
    • T. Yamashita, K. Sawamoto, S. Suzuki, N. Suzuki, K. Adachi, T. Kawase, M. Mihara, Y. Ohsugi, K. Abe, and H. Okano Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons J. Neurochem. 94 2005 459 468
    • (2005) J. Neurochem. , vol.94 , pp. 459-468
    • Yamashita, T.1    Sawamoto, K.2    Suzuki, S.3    Suzuki, N.4    Adachi, K.5    Kawase, T.6    Mihara, M.7    Ohsugi, Y.8    Abe, K.9    Okano, H.10
  • 27
    • 80052033130 scopus 로고    scopus 로고
    • Carnosine pretreatment protects against hypoxia-ischemia brain damage in the neonatal rat model
    • X. Zhang, L. Song, X. Cheng, Y. Yang, B. Luan, L. Jia, F. Xu, and Z. Zhang Carnosine pretreatment protects against hypoxia-ischemia brain damage in the neonatal rat model Eur. J. Pharmacol. 667 2011 202 207
    • (2011) Eur. J. Pharmacol. , vol.667 , pp. 202-207
    • Zhang, X.1    Song, L.2    Cheng, X.3    Yang, Y.4    Luan, B.5    Jia, L.6    Xu, F.7    Zhang, Z.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.