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Volumn 14, Issue 1, 2013, Pages

Side chain requirements for affinity and specificity in D5, an HIV-1 antibody derived from the VH1-69 germline segment

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; D5 ANTIBODY; HISTIDINE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; PROLINE; SERINE; TYROSINE; UNCLASSIFIED DRUG;

EID: 84875825670     PISSN: None     EISSN: 14712091     Source Type: Journal    
DOI: 10.1186/1471-2091-14-9     Document Type: Article
Times cited : (3)

References (45)
  • 1
    • 64949085560 scopus 로고    scopus 로고
    • Therapeutic antibodies: Current state and future trends - Is a paradigm change coming soon?
    • 10.1007/978-1-59745-554-1-1 19252861
    • Therapeutic antibodies: current state and future trends-is a paradigm change coming soon? Dimitrov DS, Marks JD, Methods Mol Biol 2009 525 1 27 10.1007/978-1-59745-554-1-1 19252861
    • (2009) Methods Mol Biol , vol.525 , pp. 1-27
    • Dimitrov, D.S.1    Marks, J.D.2
  • 3
    • 33751080719 scopus 로고    scopus 로고
    • Synthetic therapeutic antibodies
    • 10.1038/nchembio843 17108986
    • Synthetic therapeutic antibodies. Sidhu SS, Fellouse FA, Nat Chem Biol 2006 2 682 686 10.1038/nchembio843 17108986
    • (2006) Nat Chem Biol , vol.2 , pp. 682-686
    • Sidhu, S.S.1    Fellouse, F.A.2
  • 4
    • 49549102657 scopus 로고    scopus 로고
    • Understanding mechanisms governing protein-protein interactions from synthetic binding interfaces
    • 10.1016/j.sbi.2008.06.004 18638552
    • Understanding mechanisms governing protein-protein interactions from synthetic binding interfaces. Kossiakoff AA, Koide S, Curr Opin Struct Biol 2008 18 499 506 10.1016/j.sbi.2008.06.004 18638552
    • (2008) Curr Opin Struct Biol , vol.18 , pp. 499-506
    • Kossiakoff, A.A.1    Koide, S.2
  • 5
    • 77954204655 scopus 로고    scopus 로고
    • Contribution of light chain residues to high affinity binding in an HIV-1 antibody explored by combinatorial scanning mutagenesis
    • 10.1021/bi100293q 20518570
    • Contribution of light chain residues to high affinity binding in an HIV-1 antibody explored by combinatorial scanning mutagenesis. Da Silva GF, Harrison JS, Lai JR, Biochemistry 2010 49 5464 5472 10.1021/bi100293q 20518570
    • (2010) Biochemistry , vol.49 , pp. 5464-5472
    • Da Silva, G.F.1    Harrison, J.S.2    Lai, J.R.3
  • 12
    • 34848868199 scopus 로고    scopus 로고
    • Acharya, P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CR, and Kwong PD: Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
    • 10.1126/science.1145373 17901336
    • Acharya, P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CR, and Kwong PD: Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Huang CC, Lam SN, Science 2007 317 1930 1934 10.1126/science.1145373 17901336
    • (2007) Science , vol.317 , pp. 1930-1934
    • Huang, C.C.1    Lam, S.N.2
  • 13
    • 65749107719 scopus 로고    scopus 로고
    • HIV-1 and influenza antibodies: Seeing antigens in new ways
    • 10.1038/ni.1746 19448659
    • HIV-1 and influenza antibodies: seeing antigens in new ways. Kwong PD, Wilson IA, Nat Immunol 2009 10 573 578 10.1038/ni.1746 19448659
    • (2009) Nat Immunol , vol.10 , pp. 573-578
    • Kwong, P.D.1    Wilson, I.A.2
  • 15
    • 79952640176 scopus 로고    scopus 로고
    • Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire
    • 10.1039/c0mb00310g 21298133
    • Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire. Lerner RA, Mol Biosyst 2011 7 1004 1012 10.1039/c0mb00310g 21298133
    • (2011) Mol Biosyst , vol.7 , pp. 1004-1012
    • Lerner, R.A.1
  • 18
    • 77953591801 scopus 로고    scopus 로고
    • The functional capacity of the natural amino acids for molecular recognition
    • 10.1039/b927393j 20383388
    • The functional capacity of the natural amino acids for molecular recognition. Birtalan S, Fisher RD, Sidhu SS, Mol Biosyst 2010 6 1186 1194 10.1039/b927393j 20383388
    • (2010) Mol Biosyst , vol.6 , pp. 1186-1194
    • Birtalan, S.1    Fisher, R.D.2    Sidhu, S.S.3
  • 19
    • 80053596391 scopus 로고    scopus 로고
    • Synthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions
    • 10.1016/j.bbrc.2011.09.012
    • Synthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions. Liu Y, Regula LK, Stewart A, Lai JR, Biophys Biochem Res Commun 2011 413 611 615 10.1016/j.bbrc.2011.09.012
    • (2011) Biophys Biochem Res Commun , vol.413 , pp. 611-615
    • Liu, Y.1    Regula, L.K.2    Stewart, A.3    Lai, J.R.4
  • 20
    • 33845726659 scopus 로고    scopus 로고
    • Manufacturing immunity to disease in a test tube: The magic bullet realized
    • Manufacturing immunity to disease in a test tube: the magic bullet realized. Lerner RA, Angew Chem Intl Ed 2006 45 8105 8125
    • (2006) Angew Chem Intl Ed , vol.45 , pp. 8105-8125
    • Lerner, R.A.1
  • 21
    • 0032560552 scopus 로고    scopus 로고
    • Synthetic human antibodies and a strategy for protein engineering
    • 10.1016/S0014-5793(98)00628-0 9678601
    • Synthetic human antibodies and a strategy for protein engineering. Winter G, FEBS Lett 1998 430 92 94 10.1016/S0014-5793(98)00628-0 9678601
    • (1998) FEBS Lett , vol.430 , pp. 92-94
    • Winter, G.1
  • 22
    • 62549093913 scopus 로고    scopus 로고
    • Two-state selection of conformation-specific antibodies
    • 10.1073/pnas.0812952106 19208804
    • Two-state selection of conformation-specific antibodies. Gao J, Sidhu SS, Wells JA, Proc Natl Acad Sci USA 2009 106 3071 3076 10.1073/pnas.0812952106 19208804
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3071-3076
    • Gao, J.1    Sidhu, S.S.2    Wells, J.A.3
  • 23
    • 79956340760 scopus 로고    scopus 로고
    • Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design
    • 10.1073/pnas.1102294108 21518904
    • Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Gilbreth RN, Truong K, Madu I, Koide A, Wojcik JB, Li NS, Piccirilli JA, Chen Y, Koide S, Proc Natl Acad Sci USA 2011 108 7751 7756 10.1073/pnas.1102294108 21518904
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 7751-7756
    • Gilbreth, R.N.1    Truong, K.2    Madu, I.3    Koide, A.4    Wojcik, J.B.5    Li, N.S.6    Piccirilli, J.A.7    Chen, Y.8    Koide, S.9
  • 24
    • 78649737276 scopus 로고    scopus 로고
    • Characterization of engineered actin binding proteins that control filament assembly and structure
    • Characterization of engineered actin binding proteins that control filament assembly and structure. Brawley CM, Uysal S, Kossiakoff AA, Rock RS, PLoS One 2010 12 13960
    • (2010) PLoS One , vol.12 , pp. 513960
    • Brawley, C.M.1    Uysal, S.2    Kossiakoff, A.A.3    Rock, R.S.4
  • 25
    • 84869465815 scopus 로고    scopus 로고
    • Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the Ebola virus envelope glycoprotein
    • 10.1002/cbic.201200493 23111988
    • Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the Ebola virus envelope glycoprotein. Koellhoffer JF, Chen G, Sandesara RG, Bale S, Saphire EO, Chandran K, Sidhu SS, Lai JR, Chembiochem 2012 13 2549 2557 10.1002/cbic.201200493 23111988
    • (2012) Chembiochem , vol.13 , pp. 2549-2557
    • Koellhoffer, J.F.1    Chen, G.2    Sandesara, R.G.3    Bale, S.4    Saphire, E.O.5    Chandran, K.6    Sidhu, S.S.7    Lai, J.R.8
  • 26
    • 4344714933 scopus 로고    scopus 로고
    • Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition
    • 10.1073/pnas.0401786101
    • Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition. Fellouse FA, Wiesmann C, Sidhu SS, Proc Natl Acad USA 2004 101 12467 12472 10.1073/pnas.0401786101
    • (2004) Proc Natl Acad USA , vol.101 , pp. 12467-12472
    • Fellouse, F.A.1    Wiesmann, C.2    Sidhu, S.S.3
  • 27
    • 3242760800 scopus 로고    scopus 로고
    • High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold
    • 10.1016/j.jmb.2004.05.051
    • High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold. Lee CV, Liang WC, Dennis MS, Eigenbrot C, Sidhu SS, Fuh G, J Mol Bio 2004 340 1073 1093 10.1016/j.jmb.2004. 05.051
    • (2004) J Mol Bio , vol.340 , pp. 1073-1093
    • Lee, C.V.1    Liang, W.C.2    Dennis, M.S.3    Eigenbrot, C.4    Sidhu, S.S.5    Fuh, G.6
  • 28
    • 80052740699 scopus 로고    scopus 로고
    • Humoral immune response to Keyhole Limpet Haemocyanin, the protein carrier in cancer vaccines
    • 21716728
    • Humoral immune response to Keyhole Limpet Haemocyanin, the protein carrier in cancer vaccines. Kantele A, Hakkinen MP, Zivny J, Elson CO, Mestecky J, Katele JM, Clin Dev Immunol 2011 2011 614383 21716728
    • (2011) Clin Dev Immunol , vol.2011 , pp. 614383
    • Kantele, A.1    Hakkinen, M.P.2    Zivny, J.3    Elson, C.O.4    Mestecky, J.5    Katele, J.M.6
  • 29
    • 33749032790 scopus 로고    scopus 로고
    • Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion
    • 10.1073/pnas.0601036103 16963566
    • Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion. Frey G, Rits-Volloch S, Zhang XQ, Schooley RT, Chen B, Harrison SC, Proc Natl Acad Sci USA 2006 103 13938 13943 10.1073/pnas. 0601036103 16963566
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13938-13943
    • Frey, G.1    Rits-Volloch, S.2    Zhang, X.Q.3    Schooley, R.T.4    Chen, B.5    Harrison, S.C.6
  • 30
    • 0035793406 scopus 로고    scopus 로고
    • Protein design of an HIV-1 entry inhibitor
    • 10.1126/science.1057453 11229405
    • Protein design of an HIV-1 entry inhibitor. Root MJ, Kay MS, Kim PS, Science 2001 291 884 888 10.1126/science.1057453 11229405
    • (2001) Science , vol.291 , pp. 884-888
    • Root, M.J.1    Kay, M.S.2    Kim, P.S.3
  • 31
    • 46449100666 scopus 로고    scopus 로고
    • Viral membrane fusion
    • 10.1038/nsmb.1456 18596815
    • Viral membrane fusion. Harrison SC, Nat Struct Mol Biol 2008 15 690 698 10.1038/nsmb.1456 18596815
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 690-698
    • Harrison, S.C.1
  • 32
    • 0034924823 scopus 로고    scopus 로고
    • Mechanisms of viral membrane fusion and its inhibition
    • 10.1146/annurev.biochem.70.1.777 11395423
    • Mechanisms of viral membrane fusion and its inhibition. Eckert DM, Kim PS, Annu Rev Biochem 2001 70 777 810 10.1146/annurev.biochem.70.1.777 11395423
    • (2001) Annu Rev Biochem , vol.70 , pp. 777-810
    • Eckert, D.M.1    Kim, P.S.2
  • 33
    • 77955275844 scopus 로고    scopus 로고
    • Novel recombinant engineered gp41 N-terminal heptad repeat trimers and their potential as anti-HIV-1 therapeutics or microbicides
    • 10.1074/jbc.M110.101170 20538590
    • Novel recombinant engineered gp41 N-terminal heptad repeat trimers and their potential as anti-HIV-1 therapeutics or microbicides. Chen X, Lu L, Qi Z, Lu H, Wang J, Yu X, Chen Y, Jiang S, J Biol Chem 2010 285 25506 25515 10.1074/jbc.M110.101170 20538590
    • (2010) J Biol Chem , vol.285 , pp. 25506-25515
    • Chen, X.1    Lu, L.2    Qi, Z.3    Lu, H.4    Wang, J.5    Yu, X.6    Chen, Y.7    Jiang, S.8
  • 34
    • 0034255454 scopus 로고    scopus 로고
    • Rapid mapping of protein functional epitopes by combinatorial alanine scanning
    • 10.1073/pnas.160252097 10908667
    • Rapid mapping of protein functional epitopes by combinatorial alanine scanning. Weiss GA, Watanabe CK, Zhong A, Goddard A, Sidhu SS, Proc Natl Acad Sci USA 2000 97 8950 8954 10.1073/pnas.160252097 10908667
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8950-8954
    • Weiss, G.A.1    Watanabe, C.K.2    Zhong, A.3    Goddard, A.4    Sidhu, S.S.5
  • 35
    • 24344495780 scopus 로고    scopus 로고
    • Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis
    • 10.1110/ps.051519805 16131663
    • Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis. Pál G, Fong S-Y, Kossiakoff AA, Sidhu SS, Protein Sci 2005 14 2405 2413 10.1110/ps.051519805 16131663
    • (2005) Protein Sci , vol.14 , pp. 2405-2413
    • Pál, G.1    Fong, S.-Y.2    Kossiakoff, A.A.3    Sidhu, S.S.4
  • 36
    • 0036295439 scopus 로고    scopus 로고
    • Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis
    • 10.1016/S0022-2836(02)00264-4 12079396
    • Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis. Vajdos FF, Adams CW, Breece TN, Presta LG, de Vos AM, Sidhu SS, J Mol Biol 2002 320 415 428 10.1016/S0022-2836(02)00264-4 12079396
    • (2002) J Mol Biol , vol.320 , pp. 415-428
    • Vajdos, F.F.1    Adams, C.W.2    Breece, T.N.3    Presta, L.G.4    De Vos, A.M.5    Sidhu, S.S.6
  • 37
    • 33746799726 scopus 로고    scopus 로고
    • Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning
    • 10.1074/jbc.M603826200 16762925
    • Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning. Pál G, Kouadio JL, Artis DR, Kossiakoff AA, Sidhu SS, J Biol Chem 2006 281 22378 22385 10.1074/jbc.M603826200 16762925
    • (2006) J Biol Chem , vol.281 , pp. 22378-22385
    • Pál, G.1    Kouadio, J.L.2    Artis, D.R.3    Kossiakoff, A.A.4    Sidhu, S.S.5
  • 39
    • 0030821164 scopus 로고    scopus 로고
    • Structural insights into the evolution of an antibody combining site
    • 10.1126/science.276.5319.1665 9180069
    • Structural insights into the evolution of an antibody combining site. Wedemayer GJ, Patten PA, Wang LH, Schultz PG, Stevens RC, Science 1997 276 1665 1669 10.1126/science.276.5319.1665 9180069
    • (1997) Science , vol.276 , pp. 1665-1669
    • Wedemayer, G.J.1    Patten, P.A.2    Wang, L.H.3    Schultz, P.G.4    Stevens, R.C.5
  • 41
    • 0042744723 scopus 로고    scopus 로고
    • Structural plasticity and the evolution of antibody affinity and specificity
    • 10.1016/S0022-2836(03)00631-4 12850137
    • Structural plasticity and the evolution of antibody affinity and specificity. Yin J, Beuscher AE 4th, Andryski SE, Stevens RC, Schultz PG, J Mol Biol 2003 330 651 656 10.1016/S0022-2836(03)00631-4 12850137
    • (2003) J Mol Biol , vol.330 , pp. 651-656
    • Yin, J.1    Beuscher VI, A.E.2    Andryski, S.E.3    Stevens, R.C.4    Schultz, P.G.5
  • 42
    • 0038103565 scopus 로고    scopus 로고
    • X-ray snapshots of the maturation of an antibody response to a protein antigen
    • 10.1038/nsb930
    • X-ray snapshots of the maturation of an antibody response to a protein antigen. Li Y, Li H, Yang F, Smith-Gill SJ, Mariuzza RA, Nat Struct Mol Biol 2003 10 482 488 10.1038/nsb930
    • (2003) Nat Struct Mol Biol , vol.10 , pp. 482-488
    • Li, Y.1    Li, H.2    Yang, F.3    Smith-Gill, S.J.4    Mariuzza, R.A.5
  • 43
    • 13844272064 scopus 로고    scopus 로고
    • Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
    • 10.1016/j.str.2004.12.012 15698573
    • Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces. Li Y, Huang Y, Swaminathan CP, Smith-Gill SJ, Mariuzza RA, Structure 2005 13 297 307 10.1016/j.str.2004.12.012 15698573
    • (2005) Structure , vol.13 , pp. 297-307
    • Li, Y.1    Huang, Y.2    Swaminathan, C.P.3    Smith-Gill, S.J.4    Mariuzza, R.A.5
  • 45
    • 2942727133 scopus 로고    scopus 로고
    • Chapter 2: Constructing phage display libraries by oligonucleotide- directed mutagenesis
    • New York, NY: Oxford University Press Clackson T, Lowman HB
    • Chapter 2: Constructing phage display libraries by oligonucleotide- directed mutagenesis. Sidhu SS, Weiss GA, Phage display: a practical approach New York, NY: Oxford University Press, Clackson T, Lowman HB, 27 41
    • Phage Display: A Practical Approach , pp. 27-41
    • Sidhu, S.S.1    Weiss, G.A.2


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