Molecular signature of disease onset in Granulin mutation carriers: A gene expression analysis study

Neurobiology of Aging

Volumn 34, Issue 7, 2013, Pages 1837-1845

  Milanesi, Elena ^a   Bonvicini, Cristian ^b   Alberici, Antonella ^c   Pilotto, Andrea ^c   Cattane, Nadia ^a   Premi, Enrico ^c   Gazzina, Stefano ^c   Archetti, Silvana ^d   Gasparotti, Roberto ^c   Cancelli, Vanessa ^c   Gennarelli, Massimo ^a,b   Padovani, Alessandro ^c   Borroni, Barbara ^c  

^a UNIVERSITY OF BRESCIA   (Italy)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^c UNIVERSITY OF BRESCIA   (Italy)

^d Department of Paediatrics   (Italy)

Author keywords

Frontotemporal dementia; Frontotemporal lobar degeneration; Gene expression; Granulin; Inflammation; Mutations; Progranulin

Indexed keywords

MESSENGER RNA;

ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BRAIN ATROPHY; BRAIN DAMAGE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GRN GENE; HETEROZYGOTE; HUMAN; INFLAMMATION; LEUKOCYTE; MALE; MICROARRAY ANALYSIS; ONSET AGE; PARIETAL LOBE; PATHOGENESIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIBLING; SUPERIOR FRONTAL GYRUS; VOXEL BASED MORPHOMETRY;

ADULT; AGED; COHORT STUDIES; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; GENE EXPRESSION REGULATION; HETEROZYGOTE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOCYTES; MALE; MIDDLE AGED; MUTATION; PROTEIN ARRAY ANALYSIS;

EID: 84875822759     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.11.016     Document Type: Article

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