Founder effect and estimation of the age of the Progranulin Thr272fs mutation in 14 Italian pedigrees with frontotemporal lobar degeneration

Neurobiology of Aging

Volumn 32, Issue 3, 2011, Pages 555.e1-555.e8

  Borroni, Barbara ^a   Bonvicini, Cristian ^b   Galimberti, Daniela ^c   Tremolizzo, Lucio ^d   Papetti, Alice ^a   Archetti, Silvana ^e   Turla, Marinella ^f   Alberici, Antonella ^a   Agosti, Chiara ^a   Premi, Enrico ^a   Appollonio, Ildebrando ^d   Rainero, Innocenzo ^g   Ferrarese, Carlo ^d   Gennarelli, Massimo ^b,h   Scarpini, Elio ^c   Padovani, Alessandro ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^d UNIVERSITY OF MILANO BICOCCA   (Italy)

^e Department of Paediatrics   (Italy)

^f Vallecamonica Hospital   (Italy)

^g UNIVERSITY OF TURIN   (Italy)

^h UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Common founder; Frontotemporal dementia; Frontotemporal lobar degeneration; Haplotype; Mutation; Progranulin

Indexed keywords

PROGRANULIN;

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE FREQUENCY; GENE MUTATION; HAPLOTYPE; HETEROZYGOSITY; HUMAN; ITALY; MALE; MICROSATELLITE MARKER; NEOLITHIC; ONSET AGE; PATHOGENESIS; PEDIGREE; PGRN GENE; PRIMARY PROGRESSIVE APHASIA; PRIORITY JOURNAL;

EID: 79952899795     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.08.009     Document Type: Article

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