Lis1 controls dynamics of neuronal filopodia and spines to impact synaptogenesis and social behaviour

EMBO Molecular Medicine

Volumn 5, Issue 4, 2013, Pages 591-607

  Sudarov, Anamaria ^a   Gooden, Frank ^b   Tseng, Debbie ^a   Gan, Wen Biao ^b   Ross, Margaret Elizabeth ^a  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autism relevant behaviour; Cytoskeletal dynamics; Rho GTPases; Schizophrenia relevant behaviour; Synapse development

Indexed keywords

RHO KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN POLYMERIZATION; ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN NERVE CELL; CELL DENSITY; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DENDRITIC SPINE; FILOPODIUM; GENE; GENE DELETION; HIPPOCAMPUS; LIS1 GENE; MALE; MOLECULAR DYNAMICS; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RECOGNITION; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SYNAPTOGENESIS; TIME LAPSE IMAGING;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; AUTISTIC DISORDER; BEHAVIOR; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; PSEUDOPODIA; SYNAPSES;

EID: 84875810459     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201202106     Document Type: Article

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