The Rho-Kinase (ROCK) inhibitor Y-27632 protects against excitotoxicity-induced neuronal death in vivo and in vitro

Neurotoxicity Research

Volumn 23, Issue 3, 2013, Pages 238-248

  Jeon, Byeong Tak ^a   Jeong, Eun Ae ^a   Park, Sun Young ^a   Son, Hyeonwi ^a   Shin, Hyun Joo ^a   Lee, Dong Hoon ^a   Kim, Hyun Joon ^a   Kang, Sang Soo ^a   Cho, Gyeong Jae ^a   Choi, Wan Sung ^a   Roh, Gu Seob ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Excitotoxicity; Neuron; Rho kinase; Y 27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PROTEIN KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ROCK2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL DEATH; CONTROLLED STUDY; EXCITOTOXICITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE DEGENERATION; NEURITE; NEURITE DYSTROPHY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

AMIDES; ANIMALS; ANTICONVULSANTS; ASTROCYTES; CELL DEATH; CELLS, CULTURED; CONVULSANTS; GLUTAMIC ACID; HIPPOCAMPUS; KAINIC ACID; MALE; MICE; MICE, INBRED ICR; MYOSIN LIGHT CHAINS; NERVE TISSUE PROTEINS; NEURITES; NEURONS; NEUROTOXINS; PROTEIN KINASE INHIBITORS; PYRIDINES; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SEIZURES; SINGLE-BLIND METHOD;

MUS;

EID: 84876290624     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-012-9339-2     Document Type: Article

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