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Volumn 8, Issue , 2009, Pages

PIK3CA alterations in Middle Eastern ovarian cancers

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; GENOMIC DNA; K RAS PROTEIN; KI 67 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P53; SERINE; BRAF PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PIK3CA PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; RAS PROTEIN; TP53 PROTEIN, HUMAN; TUMOR MARKER;

EID: 68949212362     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-8-51     Document Type: Article
Times cited : (33)

References (46)
  • 1
    • 0036361955 scopus 로고    scopus 로고
    • The scientific basis of early detection of epithelial ovarian cancer: The national ovarian cancer early detection program (NOCEDP)
    • Boston: Kluwer Academic Publishers Stack MS, Fishman DA
    • Fishman DA Bozorgi K The scientific basis of early detection of epithelial ovarian cancer: The national ovarian cancer early detection program (NOCEDP) Cancer Treatment and Research: Ovarian Cancer Boston: Kluwer Academic Publishers Stack MS, Fishman DA 2001, 3:28.
    • (2001) Cancer Treatment and Research: Ovarian Cancer , pp. 3-28
    • Fishman, D.A.1    Bozorgi, K.2
  • 2
    • 34447560089 scopus 로고    scopus 로고
    • Role of surgery in ovarian carcinoma
    • 10.1200/JCO.2007.11.0932 17617518
    • Fader AN Rose PG Role of surgery in ovarian carcinoma J Clin Oncol 2007, 25:2873-2883. 10.1200/JCO.2007.11.0932 17617518
    • (2007) J Clin Oncol , vol.25 , pp. 2873-2883
    • Fader, A.N.1    Rose, P.G.2
  • 3
  • 4
    • 19744368302 scopus 로고    scopus 로고
    • Medical progress: Cancer of the ovary
    • 10.1056/NEJMra041842 15590954
    • Cannistra SA Medical progress: Cancer of the ovary New England Journal of Medicine 2004, 351:2519-2529. 10.1056/NEJMra041842 15590954
    • (2004) New England Journal of Medicine , vol.351 , pp. 2519-2529
    • Cannistra, S.A.1
  • 6
    • 2342439646 scopus 로고    scopus 로고
    • Comparison between primary peritoneal and epithelial ovarian carcinoma: A population-based study
    • 10.1016/j.ajog.2003.09.073 15118638
    • Barda G Menczer J Chetrit A Lubin F Beck D Piura B Glezerman M Modan B Sadetzki S Comparison between primary peritoneal and epithelial ovarian carcinoma: A population-based study Am J Obstet Gynecol 2004, 190:1039-45. 10.1016/j.ajog.2003.09.073 15118638
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 1039-1045
    • Barda, G.1    Menczer, J.2    Chetrit, A.3    Lubin, F.4    Beck, D.5    Piura, B.6    Glezerman, M.7    Modan, B.8    Sadetzki, S.9
  • 7
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • 10.1126/science.296.5573.1655 12040186
    • Cantley LC The phosphoinositide 3-kinase pathway Science 2002, 296:1655-1657. 10.1126/science.296.5573.1655 12040186
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 8
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase AKT pathway in human cancer
    • 10.1038/nrc839 12094235
    • Vivanco I Sawyers CL The phosphatidylinositol 3-kinase AKT pathway in human cancer Nat Rev Cancer 2002, 2:489-501. 10.1038/nrc839 12094235
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 10
    • 33947184242 scopus 로고    scopus 로고
    • Alternate molecular genetic pathways in ovarian carcinomas of common histological types
    • 10.1016/j.humpath.2006.10.007 17258789
    • Willner J Wurz K Allison KH Galic V Garcia RL Goff BA Swisher EM Alternate molecular genetic pathways in ovarian carcinomas of common histological types Hum Pathol 2007, 38:607-13. 10.1016/ j.humpath.2006.10.007 17258789
    • (2007) Hum Pathol , vol.38 , pp. 607-613
    • Willner, J.1    Wurz, K.2    Allison, K.H.3    Galic, V.4    Garcia, R.L.5    Goff, B.A.6    Swisher, E.M.7
  • 12
    • 34848891922 scopus 로고    scopus 로고
    • Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer
    • 10.1158/1078-0432.CCR-06-2660 17875760
    • Zhang L Huang J Yang N Greshock J Liang S Hasegawa K Giannakakis A Poulos N O'Brien-Jenkins A Katsaros D Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer Clin Cancer Res 2007, 13:5314-21. 10.1158/1078-0432.CCR-06-2660 17875760
    • (2007) Clin Cancer Res , vol.13 , pp. 5314-5321
    • Zhang, L.1    Huang, J.2    Yang, N.3    Greshock, J.4    Liang, S.5    Hasegawa, K.6    Giannakakis, A.7    Poulos, N.8    O'Brien-Jenkins, A.9    Katsaros, D.10
  • 13
    • 33947514699 scopus 로고    scopus 로고
    • Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer
    • 10.1007/s00428-006-0358-3 17377809
    • Woenckhaus J Steger K Sturm K Münstedt K Franke FE Fenic I Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer Virchows Arch 2007, 450:387-95. 10.1007/s00428-006-0358-3 17377809
    • (2007) Virchows Arch , vol.450 , pp. 387-395
    • Woenckhaus, J.1    Steger, K.2    Sturm, K.3    Münstedt, K.4    Franke, F.E.5    Fenic, I.6
  • 15
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • 10.1677/erc.1.0978 15947100
    • Xing M BRAF mutation in thyroid cancer Endocr Relat Cancer 2005, 12:245-62. 10.1677/erc.1.0978 15947100
    • (2005) Endocr Relat Cancer , vol.12 , pp. 245-262
    • Xing, M.1
  • 16
    • 0037454224 scopus 로고    scopus 로고
    • Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma
    • 12644542
    • Singer G Oldt R 3rd Cohen Y Wang BG Sidransky D Kurman RJ Shihe M Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma JNCI 2003, 95:484-486. 12644542
    • (2003) JNCI , vol.95 , pp. 484-486
    • Singer, G.1    Oldt III, R.2    Cohen, Y.3    Wang, B.G.4    Sidransky, D.5    Kurman, R.J.6    Shihe, M.7
  • 20
    • 0001833641 scopus 로고
    • Surface epithelial-stromal tumors of the ovary
    • New York: Springer-Verlag Kurman RJ
    • Russel P Surface epithelial-stromal tumors of the ovary Blaustein's Pathology of the Female Genital Tract New York: Springer-Verlag Kurman RJ 1995, 705-782.
    • (1995) Blaustein's Pathology of the Female Genital Tract , pp. 705-782
    • Russel, P.1
  • 22
    • 35548956906 scopus 로고    scopus 로고
    • PIK3CA mutations are mutually exclusive with PTEN loss in diffuse large B-cell lymphoma
    • 10.1038/sj.leu.2404873 17657213
    • Abubaker J Bavi PP Al-Harbi S Siraj AK Al-Dayel F Uddin S Al-Kuraya K PIK3CA mutations are mutually exclusive with PTEN loss in diffuse large B-cell lymphoma Leukemia 2007, 21:2368-70. 10.1038/sj.leu.2404873 17657213
    • (2007) Leukemia , vol.21 , pp. 2368-2370
    • Abubaker, J.1    Bavi, P.P.2    Al-Harbi, S.3    Siraj, A.K.4    Al-Dayel, F.5    Uddin, S.6    Al-Kuraya, K.7
  • 23
    • 20144387695 scopus 로고    scopus 로고
    • PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
    • 10.1158/0008-5472-CAN-04-3913 15805248
    • Saal LH Holm K Maurer M Memeo L Su T Wang X Yu JS Malmström PO Mansukhani M Enoksson J Hibshoosh H Borg A PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma Cancer Res 2005, 65:2554-2559. 10.1158/0008-5472-CAN-04-3913 15805248
    • (2005) Cancer Res , vol.65 , pp. 2554-2559
    • Saal, L.H.1    Holm, K.2    Maurer, M.3    Memeo, L.4    Su, T.5    Wang, X.6    Yu, J.S.7    Malmström, P.O.8    Mansukhani, M.9    Enoksson, J.10    Hibshoosh, H.11    Borg, A.12
  • 27
    • 8444244786 scopus 로고    scopus 로고
    • X-tile: A new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization
    • 10.1158/1078-0432.CCR-04-0713 15534099
    • Camp RL Dolled-Filhart M Rimm DL X-tile: A new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization Clin Cancer Res 2004, 10:7252-7259. 10.1158/1078-0432.CCR-04-0713 15534099
    • (2004) Clin Cancer Res , vol.10 , pp. 7252-7259
    • Camp, R.L.1    Dolled-Filhart, M.2    Rimm, D.L.3
  • 28
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST(C)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • 113859 11972351 10.1093/nar/30.9.e36
    • Pfaffl MW Horgan GW Dempfle L Relative expression software tool (REST(C)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR Nucl Acids Res 2002, 30:e36. 113859 11972351 10.1093/nar/30.9.e36
    • (2002) Nucl Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 32
    • 53749098937 scopus 로고    scopus 로고
    • Expression of phosphorylated protein kinase B and PTEN protein in ovarian epithelial cancer
    • 17673045
    • Qiao YH Cheng J Guo RX Expression of phosphorylated protein kinase B and PTEN protein in ovarian epithelial cancer Zhonghua Fu Chan Ke Za Zhi 2007, 42:325-9. 17673045
    • (2007) Zhonghua Fu Chan Ke Za Zhi , vol.42 , pp. 325-329
    • Qiao, Y.H.1    Cheng, J.2    Guo, R.X.3
  • 34
    • 0034976644 scopus 로고    scopus 로고
    • Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
    • 1891985 11395387
    • Kurose K Zhou XP Araki T Cannistra SA Maher ER Eng C Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas Am J Pathol 2001, 158:2097-106. 1891985 11395387
    • (2001) Am J Pathol , vol.158 , pp. 2097-2106
    • Kurose, K.1    Zhou, X.P.2    Araki, T.3    Cannistra, S.A.4    Maher, E.R.5    Eng, C.6
  • 35
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • 10.1038/nrc1819 16453012
    • Cully M You H Levine AJ Mak TW Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis Nat Rev Cancer 2006, 6:184-92. 10.1038/nrc1819 16453012
    • (2006) Nat Rev Cancer , vol.6 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 36
    • 19944374798 scopus 로고    scopus 로고
    • Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
    • 10.1038/sj.onc.1208463 15806173
    • Wang HQ Altomare DA Skele KL Poulikakos PI Kuhajda FP Di Cristofano A Testa JR Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells Oncogene 2005, 24:3574-82. 10.1038/sj.onc.1208463 15806173
    • (2005) Oncogene , vol.24 , pp. 3574-3582
    • Wang, H.Q.1    Altomare, D.A.2    Skele, K.L.3    Poulikakos, P.I.4    Kuhajda, F.P.5    Di Cristofano, A.6    Testa, J.R.7
  • 37
    • 42149102636 scopus 로고    scopus 로고
    • Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer
    • 10.1242/jcs.013029 18270270
    • Astanehe A Arenillas D Wasserman WW Leung PC Dunn SE Davies BR Mills GB Auersperg N Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer J Cell Sci 2008, 121:664-74. 10.1242/jcs.013029 18270270
    • (2008) J Cell Sci , vol.121 , pp. 664-674
    • Astanehe, A.1    Arenillas, D.2    Wasserman, W.W.3    Leung, P.C.4    Dunn, S.E.5    Davies, B.R.6    Mills, G.B.7    Auersperg, N.8
  • 38
    • 33846854921 scopus 로고    scopus 로고
    • Clinicopathologic analysis of breast cancers with PIK3CA mutations in Japanese women
    • 10.1158/1078-0432.CCR-06-0267 17202311
    • Maruyama N Miyoshi Y Taguchi T Tamaki Y Monden M Noguchi S Clinicopathologic analysis of breast cancers with PIK3CA mutations in Japanese women Clin Cancer Res 2007, 13:408-414. 10.1158/ 1078-0432.CCR-06-0267 17202311
    • (2007) Clin Cancer Res , vol.13 , pp. 408-414
    • Maruyama, N.1    Miyoshi, Y.2    Taguchi, T.3    Tamaki, Y.4    Monden, M.5    Noguchi, S.6
  • 45
    • 1542510675 scopus 로고    scopus 로고
    • B-Raf is dispensable for KRAS-mediated oncogenesis in human cancer cells
    • 10.1158/0008-5472.CAN-03-3862 15026326
    • Kim JS Lee C Foxworth A Waldman T B-Raf is dispensable for KRAS-mediated oncogenesis in human cancer cells Cancer Res 2004, 64:1932-7. 10.1158/ 0008-5472.CAN-03-3862 15026326
    • (2004) Cancer Res , vol.64 , pp. 1932-1937
    • Kim, J.S.1    Lee, C.2    Foxworth, A.3    Waldman, T.4


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