Trophectoderm grade predicts outcomes of single-blastocyst transfers

Fertility and Sterility

Volumn 99, Issue 5, 2013, Pages

  Hill, Micah J ^a,b   Richter, Kevin S ^a   Heitmann, Ryan J ^a,b   Graham, James R ^a   Tucker, Michael J ^a   Decherney, Alan H ^a,b   Browne, Paulette E ^a   Levens, Eric D ^a,b  

^a Shady Grove Fertility Reproductive Science Center   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

ART; embryo stage; inner cell mass; live birth; Trophectoderm

Indexed keywords

CHORIONIC GONADOTROPIN; GANIRELIX; LEUPRORELIN;

ARTICLE; BIRTH RATE; BLASTOCYST; CELL EXPANSION; CELL STRUCTURE; COHORT ANALYSIS; DRUG DOSE REDUCTION; ECTODERM; EMBRYO TRANSFER; FEMALE; HUMAN; HUMAN CELL; INFERTILITY THERAPY; INNER CELL MASS; LIVE BIRTH; NIDATION; PREDICTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TROPHECTODERM;

EID: 84875732513     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.12.003     Document Type: Article

References (29)

1. J.M. Csokmay, M.J. Hill, R.J. Chason, S. Hennessy, A.N. James, and J. Cohen Experience with a patient-friendly, mandatory, single-blastocyst transfer policy: the power of one Fertil Steril 96 2011 580 584
2. G.L. Ryan, A.E. Sparks, C.S. Sipe, C.H. Syrop, A. Dokras, and B.J. van Voorhis A mandatory single blastocyst transfer policy with educational campaign in a United States IVF program reduces multiple gestation rates without sacrificing pregnancy rates Fertil Steril 88 2007 354 360
3. J.D. Kresowik, B.J. Stegmann, A.E. Sparks, G.L. Ryan, and B.J. van Voorhis Five-years of a mandatory single-embryo transfer (mSET) policy dramatically reduces twinning rate without lowering pregnancy rates Fertil Steril 96 2011 1367 1369
4. D.K. Gardner, and W.B. Schoolcraft In vitro culture of human blastocyst J.R. Mortimer, Toward Reproductive Certainty: Infertility and Genetics Beyond 1999 1999 Parthenon Press Carnforth, UK 378 388
5. D.K. Gardner, M. Lane, J. Stevens, T. Schlenker, and W.B. Schoolcraft Blastocyst score affects implantation and pregnancy outcome: toward a single blastocyst transfer Fertil Steril 73 2000 1155 1158
6. D.K. Gardner, E. Surrey, D. Minjarez, A. Leitz, J. Stevens, and W.B. Schoolcraft Single blastocyst transfer: a prospective randomized trial Fertil Steril 81 2004 551 555
7. B. Balaban, B. Urman, A. Sertac, C. Alatas, S. Aksoy, and R. Mercan Blastocyst quality affects the success of blastocyst-stage embryo transfer Fertil Steril 74 2000 282 287
8. B. Balaban, K. Yakin, and B. Urman Randomized comparison of two different blastocyst grading systems Fertil Steril 85 2006 559 563
9. S. Goto, T. Kadowaki, S. Tanaka, H. Hashimoto, S. Kokeguchi, and M. Shiotani Prediction of pregnancy rate by blastocyst morphological score and age, based on 1,488 single frozen-thawed blastocyst transfer cycles Fertil Steril 95 2011 948 952
10. K.S. Richter, D.C. Harris, S.T. Daneshmand, and B.S. Shapiro Quantitative grading of a human blastocyst: optimal inner cell mass size and shape Fertil Steril 76 2001 1157 1167
11. B. Kovacic, V. Vlaisavljevic, M. Reljic, and M. Cizek-Sajko Developmental capacity of different morphological types of day 5 human morulae and blastocysts Reprod Biomed Online 8 2004 687 694
12. A. Ahlstrom, C. Westin, E. Reismer, M. Wikland, and T. Hardarson Trophectoderm morphology: an important parameter for predicting live birth after single blastocyst transfer Hum Reprod 26 2011 3289 3296
13. H. Honnma, T. Baba, M. Sasaki, Y. Hashiba, H. Ohno, and T. Fukunaga Trophectoderm morphology significantly affects the rates of ongoing pregnancy and miscarriage in frozen-thawed single-blastocyst transfer cycle in vitro fertilization Fertil Stertil 98 2012 361 367
14. R.J. Stillman, K.S. Richter, N.K. Banks, and J.R. Graham Elective single embryo transfer: a 6-year progressive implementation of 784 single blastocyst transfers and the influence of payment method on patient choice Fertil Steril 92 2009 1895 1906
15. J. Liebermann, and M.J. Tucker Comparison of vitrification and conventional cryopreservation of day 5 and day 6 blastocysts during clinical application Fertil Steril 86 2006 20 26
16. E.D. Levens, B.W. Whitcomb, J.D. Kort, D. Materia-Hoover, and F.W. Larsen Microdose follicular flare: a viable alternative for normal-responding patients undergoing in vitro fertilization? Fertil Steril 91 2009 110 114
17. M.J. Hill, G.D. McWilliams, K.A. Miller, R.T. Scott Jr., and J.L. Frattarelli A luteal estradiol protocol for anticipated poor-responder patients may improve delivery rates Fertil Steril 91 2009 739 743
18. K. Kirkegaard, I.E. Agerholm, and H.J. Ingerslev Time-lapse monitoring as a tool for clinical embryo assessment Hum Reprod 27 2012 1277 1285
19. E.R. Norwitz, D.J. Schust, and S.J. Fisher Implantation and the survival of early pregnancy N Engl J Med 345 2001 1400 1408
20. M. Tsampalas, V. Gridelet, S. Berndt, J.M. Foidart, V. Geenen, and S. Perrier d'Hauterive Human chorionic gonadotropin: a hormone with immunological and angiogenic properties J Reprod Immunol 85 2010 93 98
21. P. Licht, V. Russu, S. Lehmeyer, and L. Wildt Molecular aspects of direct LH/hCG effects on human endometrium - lessons from intrauterine microdialysis in the human female in vivo Reprod Biol 1 2001 10 19
22. P. Licht, V. Russu, and L. Wildt On the role of human chorionic gonadotropin (hCG) in the embryo-endometrial microenvironment: implications for differentiation and implantation Semin Reprod Med 19 2001 37 47
23. A. Lopata Implantation of the human embryo Hum Reprod 11 Suppl 1 1996 175 184 discussion 193-5
24. A. Dokras, I.L. Sargent, and D.H. Barlow Human blastocyst grading: an indicator of developmental potential? Hum Reprod 8 1993 2119 2127
25. S. Alfarawati, E. Fragouli, P. Colls, J. Stevens, C. Gutierrez-Mateo, and W.B. Schoolcraft The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender Fertil Steril 95 2011 520 524
26. M. Meseguer, I. Rubio, M. Cruz, N. Basile, J. Marcos, and A. Requena Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study Fertil Steril 98 2012 1481 1489
27. E.S. Filho, J.A. Noble, M. Poli, T. Griffiths, G. Emerson, and D. Wells A method for semi-automatic grading of human blastocyst microscope images Hum Reprod 27 2012 2641 2648
28. A. Uyar, and E. Seli Embryo assessment strategies and their validation for clinical use: a critical analysis of methodology Curr Opin Obstet Gynecol 24 2012 141 150
29. G. Paternot, J. Devroe, S. Debrock, T.M. d'Hooghe, and C. Spiessens Intra- and inter-observer analysis in the morphological assessment of early-stage embryos Reprod Biol Endocrinol 7 2009 105