Quantitative grading of a human blastocyst: Optimal inner cell mass size and shape

Fertility and Sterility

Volumn 76, Issue 6, 2001, Pages 1157-1167

  Richter, Kevin S ^a   Harris, Dee C ^a   Daneshmand, Said T ^a,b   Shapiro, Bruce S ^a  

^a Fertility Center Las Vegas   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

Blastocyst expansion; Blastocyst size; Blastocyst transfer; Implantation rate; In vitro fertilization; Inner cell mass size and shape; Pregnancy rate; Quantitative measurements; Trophectoderm cell number

Indexed keywords

ADULT; ARTICLE; BLASTOCYST; CELL SHAPE; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; FEMALE; HUMAN; HUMAN TISSUE; INNER CELL MASS; NIDATION; OOCYTE; PREGNANCY RATE; PRIORITY JOURNAL;

ADULT; BLASTOCYST; CELL SIZE; EMBRYO IMPLANTATION; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; PREGNANCY; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 0035195862     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)02870-9     Document Type: Article

References (48)

1. High implantation and pregnancy rates with transfer of human blastocysts developed in preimplantation stage one and blastocyst media
2. A prospective randomized trial of blastocyst culture and transfer in in-vitro fertilization
3. Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers
4. Evolution of a culture protocol for successful blastocyst development and pregnancy
5. Is blastocyst transfer useful as an alternative treatment for patients with multiple in vitro fertilization failures?
6. Initial experience with extended culture and blastocyst transfer of cryopreserved embryos
7. Comparison of blastocyst transfer with day 3 embryo transfer in similar patient populations
8. Elective transfer of embryos selected on the basis of first polar body morphology is associated with increased rates of implantation and pregnancy
9. The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology
10. Clinical use of a pronuclear stage score following intracytoplasmic sperm injection: Impact on pregnancy rates under the conditions of the German embryo protection law
11. Zygote evaluation: An efficient tool for embryo selection
12. The impact of embryo quality and quantity on implantation and the establishment of viable pregnancies
13. The relationship between embryo quality and the occurrence of multiple pregnancies
14. Embryo growth rate in vitro as an indicator of embryo quality in IVF cycles
15. Embryo score to predict implantation after in-vitro fertilization: Based on 957 single embryo transfers
16. Early cleavage of in-vitro fertilized human embryos to the 2-cell stage: A novel indicator of embryo quality and viability
17. Embryo morphology or cleavage stage: How to select the best embryos for transfer after in-vitro fertilization
18. Elective transfer of one embryo results in an acceptable pregnancy rate and eliminates the risk of multiple birth
19. Morphological evaluation of human embryos and derivation of an embryo quality scoring system specific for day 3 embryos: A preliminary study
20. Human embryo fragmentation in vitro and its implications for pregnancy and implantation
21. Multinucleation in normally fertilized embryos is associated with an accelerated ovulation induction response and lower implantation and pregnancy rates in in vitro fertilization-embryo transfer cycles
22. Zona pellucida thickness variation and occurrence of visible mononucleated blastomers in preembryos are associated with a high pregnancy rate in IVF treatment
23. Embryos cultured in vitro with multinucleated blastomeres have poor implantation potential in human in-vitro fertilization and intracytoplasmic sperm injection
24. Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria: A prospective randomized clinical trial
25. Characterization of a top quality embryo, a step towards single-embryo transfer
26. Selection criteria for human embryo transfer: A comparison of pyruvate uptake and morphology
27. Assessment of embryo quality
28. Use of a bioassay for embryo-derived platelet-activating factor as a means of assessing quality and pregnancy potential of human embryos
29. Human gene expression first occurs between the four- and eight-cell stages of preimplantation development
30. A prospective, randomized study of embryo transfer results after 3 or 5 days of embryo culture in in vitro fertilization
31. Factors affecting the success of human blastocyst development and pregnancy following in vitro fertilization and embryo transfer
32. The predictive value of day 3 embryo morphology regarding blastocyst formation, pregnancy and implantation rate after day 5 transfer following in-vitro fertilization or intracytoplasmic sperm injection
33. The rate of development and time of transfer play different roles in influencing the viability of human blastocysts
34. Implantation rates after in vitro fertilization and transfer of a maximum of two embryos that have undergone three to five days of culture
35. Predictive value of 72-hour blastomere cell number on blastocyst development and success of subsequent transfer based on the degree of blastocyst development
36. A comparison of day 5 and day 6 blastocyst transfers
37. Blastocyst quality affects the success of blastocyst-stage embryo transfer
38. High implantation and pregnancy rates with transfer of human hatching day 6 blastocysts
39. The influence of in-vitro development upon post-thaw survival and implantation of cryopreserved human blastocysts
40. The morphology of human pronuclear embryos is positively related to blastocyst development and implantation
41. Differential regulation of mouse embryo development and viability by amino acids
42. In vitro uptake of glucose by bovine blastocysts
43. Assessment of embryo viability prior to transfer by the noninvasive measurement of glucose uptake
44. Selection of viable mouse blastocysts prior to transfer using a metabolic criterion
45. Blastocyst score affects implantation and pregnancy outcome: Towards a single blastocyst transfer
46. Human blastocyst grading: An indicator of developmental potential?
47. Evaluating the bovine embryo
48. Bovine embryo morphology and evaluation